triprolidine hydrochloride monohydrate, 6138-79-0

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CODE129476 CODE129476
Product(s):
TRPJIP Triprolidine HCI

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CODE129476 CODE129476
Product(s):
6138-79-0 Triprolidine hydrochloride 98%
Triprolidine hydrochloride is a potent H1 histamine receptor antagonist. It is used in allergic rhinitis, urticaria and asthma. It is an over-the-counter antihistamine with anticholinergic properties. Triprolidine hydrochloride is used in allergic rhinitis, urticaria and asthma.

Name:	2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ium-1-ylprop-1-enyl]pyridine;chloride
CAS Number:	6138-79-0	3D/inchi
FDA UNII:	YAN7R5L890
MDL:	MFCD00039044
Molecular Weight:	332.87345000
Formula:	C19 H25 Cl N2 O
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:pharmaceuticals / chemical synthisis

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
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Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Appearance:	white crystalline powder (est)
Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Boiling Point:	435.40 °C. @ 760.00 mm Hg (est)
Vapor Pressure:	0.000000 mmHg @ 25.00 °C. (est)
Flash Point:	423.00 °F. TCC ( 217.10 °C. ) (est)
logP (o/w):	4.223 (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

American International Chemical, LLC.

Triprolidine HCI

Axsyn

For experimental / research use only.

Triprolidine hydrochloride monohydrate

BOC Sciences

For experimental / research use only.

Triprolidine hydrochloride 98%

Odor: characteristic

Use: Triprolidine hydrochloride is a potent H1 histamine receptor antagonist. It is used in allergic rhinitis, urticaria and asthma. It is an over-the-counter antihistamine with anticholinergic properties. Triprolidine hydrochloride is used in allergic rhinitis, urticaria and asthma.

Sigma-Aldrich: Sigma

For experimental / research use only.

Triprolidine hydrochloride ≥99%

sds

Safety Information:

Preferred SDS: View

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50 163 mg/kg National Center for Toxicology Research Technical Report. Office of Associate Director for Scientific Coordination, Jefferson, Arkansas 72079Vol. #414/415, Pg. 1991 oral-rat LD50 840 mg/kg National Center for Toxicology Research Technical Report. Office of Associate Director for Scientific Coordination, Jefferson, Arkansas 72079Vol. #414/415, Pg. 1991
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
pharmaceuticals / chemical synthisis
Recommendation for triprolidine hydrochloride monohydrate usage levels up to:
	not for fragrance use.

Recommendation for triprolidine hydrochloride monohydrate flavor usage levels up to:
	not for flavor use.

Safety References:

Daily Med:search

Chemical Carcinogenesis Research Information System:Search

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

Carcinogenic Potency Database:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :6433473

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:3

2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ium-1-ylprop-1-enyl]pyridine;chloride

Chemidplus:0006138790

EPA/NOAA CAMEO:hazardous materials

RTECS:UT7658000 for cas# 6138-79-0

References:

	2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-ium-1-ylprop-1-enyl]pyridine;chloride
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	6433473
Pubchem (sid):	134986897

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
HMDB (The Human Metabolome Database):	Search
Export Tariff Code:	2933.90.8000
ChemSpider:	View
Wikipedia:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

not found in nature

Synonyms:

	actidil
	actidilon
2-[(1E)-1-(4-	methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl]pyridine hydrochloride hydrate
2-(1-(4-	methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)pyridine monohydrochloride hydrate
2-[(1E)-1-(4-	methylphenyl)-3-(pyrrolidin-1-yl)prop-1-en-1-yl]pyridine hydrochloride hydrate
2-[(E)-1-(4-	methylphenyl)-3-pyrrolidin-1-ium-1-ylprop-1-enyl]pyridine;chloride
2-[(1E)-1-(4-	methylphenyl)-3-pyrrolidin-1-ylprop-1-en-1-yl]pyridine hydrochloride hydrate
2-[(1E)-1-(4-	methylphenyl)-3-pyrrolidinylprop-1-enyl]pyridine, chloride, hydrate
	pro-actidil
	pro-entra
	pyridine, 2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl]-, hydrochloride, hydrate (1:1:1)
	pyridine, 2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, monohydrochloride, monohydrate
(E)-2-(3-(1-	pyrrolidinyl)-1-p-tolylpropenyl)pyridine monohydrochloride monohydrate
(E)-2-[3-(1-	pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride
trans-2-[3-(1-	pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride
	triprolidine HCl
	triprolidine hydrochloride
	triprolidine hydrochloride USP
	triprolidine.HCl monohydrate
	venen

Articles:

PubMed:Microbial transformation of the antihistaminic drug triprolidine hydrochloride.

PubMed:Pseudoephedrine and triprolidine in plasma and breast milk of nursing mothers.

PubMed:Trace analysis of the antihistamines methapyrilene hydrochloride, pyrilamine maleate and triprolidine hydrochloride monohydrate in animal feed, human urine and wastewater by high-performance liquid chromatography and gas chromatography with nitrogen-phosphorus detection.

Notes:

None found

triprolidine hydrochloride monohydrate pyridine, 2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl]-, hydrochloride, hydrate (1:1:1)

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Articles:

triprolidine hydrochloride monohydrate
pyridine, 2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl]-, hydrochloride, hydrate (1:1:1)