tripropylene glycol
propanol, ((1-methyl-1,2-ethanediyl)bis(oxy))bis-
 
Notes:
None found
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      Product(s):
      T0523 Tripropylene Glycol (mixture of isomers) >98.0%(GC)
       
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2-[2-(2-hydroxypropoxy)propoxy]propan-1-ol (Click)
CAS Number: 24800-44-0Picture of molecule
Other: 1293291-02-7
ECHA EINECS - REACH Pre-Reg: 246-466-0
Nikkaji Web: J47.851B
Beilstein Number: 2235421
MDL: MFCD00014405
XlogP3: -0.40 (est)
Molecular Weight: 192.25520000
Formula: C9 H20 O4
NMR Predictor: Predict (works with chrome or firefox)
Category: emulsifiers, humectants
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
DG SANTE Food Contact Materials: tripropyleneglycol
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Physical Properties:
Appearance: colorless to pale yellow clear liquid (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 1.02100 @  25.00 °C.
Refractive Index: 1.44400 @  20.00 °C.
Boiling Point: 271.00 °C. @ 760.00 mm Hg
Vapor Density: 6.63 ( Air = 1 )
Flash Point: > 230.00 °F. TCC ( > 110.00 °C. )
logP (o/w): -0.586 (est)
Soluble in:
 water, 1.269e+005 mg/L @ 25 °C (est)
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antioxidants
emulsion stabilisers
humectants
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Suppliers:
LyondellBasell Industries
Tripropylene Glycol
Sigma-Aldrich: Aldrich
For experimental / research use only.
Tripropylene Glycol 97%
Silver Fern Chemical
Tripropylene Glycol
Odor: characteristic
Use: Tripropylene Glycol is a versatile chemical intermediate in resins, plastics, pharmaceuticals, insecticides, dyestuffs, and mold lubricants. It has a high solvent power with low volatility and high boiling point so it is often favorable.
TCI AMERICA
For experimental / research use only.
Tripropylene Glycol (mixture of isomers) >98.0%(GC)
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  3000 mg/kg
"Industrial Hygiene and Toxicology," 2nd ed., Patty, F.A., ed., New York, John Wiley & Sons, Inc., 1958-63Vol. 2, Pg. 1522, 1963.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: emulsifiers, humectants
Recommendation for tripropylene glycol usage levels up to:
 not for fragrance use.
 
Recommendation for tripropylene glycol flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
NIOSH International Chemical Safety Cards: search
NLM Hazardous Substances Data Bank: Search
EPA Substance Registry Services (TSCA): 24800-44-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 32611
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 2-[2-(2-hydroxypropoxy)propoxy]propan-1-ol
Chemidplus: 0024800440
EPA/NOAA CAMEO: hazardous materials
RTECS: 24800-44-0
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References:
 2-[2-(2-hydroxypropoxy)propoxy]propan-1-ol
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 24800-44-0
Pubchem (cid): 32611
Pubchem (sid): 134994526
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2909.49.6000
Haz-Map: View
ChemSpider: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
2-(2-(2-hydroxypropoxy)propoxy)-1-propanol
2-[2-(2-hydroxypropoxy)propoxy]propan-1-ol
((1-methyl-1,2-ethanediyl)bis(oxy))bispropanol
 propanol, ((1-methyl-1,2-ethanediyl)bis(oxy))bis-
1-propanol, 2-[2-(2-hydroxypropoxy)propoxy]-
 tri(propylene glycol)
1,4,7-trimethyl-3,6-dioxaoctane-1,8-diol
 tripropyleneglycol
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Articles:
PubMed: Synthesis of Fullerene-Fused Dioxanes/Dioxepanes: Ferric Perchlorate-Mediated One-Step Reaction of [60]Fullerene with Diols.
PubMed: Photoswitchable hydrogel surface topographies by polymerisation-induced diffusion.
PubMed: A toxicological review of the propylene glycols.
PubMed: Safety assessment of propylene glycol, tripropylene glycol, and PPGs as used in cosmetics.
PubMed: Shear and dielectric responses of propylene carbonate, tripropylene glycol, and a mixture of two secondary amides.
PubMed: Dermal penetration of propylene glycols: measured absorption across human abdominal skin in vitro and comparison with a QSAR model.
PubMed: Effects of water contamination on the supercooled dynamics of a hydrogen-bonded model glass former.
PubMed: Polymerization of electric field-centered double emulsion droplets to create polyacrylate shells.
PubMed: Electrochemical sensor for parabens based on molecular imprinting polymers with dual-templates.
PubMed: Final report on the safety assessment of PPG-2 methyl ether, PPG-3 methyl ether, and PPG-2 methyl ether acetate.
PubMed: Paramagnetic ultrasmall gadolinium oxide nanoparticles as advanced T1 MRI contrast agent: account for large longitudinal relaxivity, optimal particle diameter, and in vivo T1 MR images.
PubMed: A novel polyurethane-based root canal-obturation material and urethane-acrylate-based root canal sealer-part 2: evaluation of push-out bond strengths.
PubMed: A novel polyurethane-based root canal-obturation material and urethane acrylate-based root canal sealer--part I: synthesis and evaluation of mechanical and thermal properties.
PubMed: Bio-oxidation of tripropylene glycol under aerobic conditions.
PubMed: Dielectric secondary relaxations in polypropylene glycols.
PubMed: Water dynamics in n-propylene glycol aqueous solutions.
PubMed: Dielectric and shear mechanical alpha and beta relaxations in seven glass-forming liquids.
PubMed: Dielectric relaxation processes in water mixtures of tripropylene glycol.
PubMed: Soot emissions from spherical droplet flames for mixtures of JP8 and tripropylene glycol monomethyl ether.
PubMed: Minimal model for Beta relaxation in viscous liquids.
PubMed: Biodegradation of potential diesel oxygenate additives: dibutyl maleate (DBM), and tripropylene glycol methyl ether (TGME).
PubMed: Binding efficiency and transport properties of molecularly imprinted polymer thin films.
PubMed: A method for measuring dermal exposure to multifunctional acrylates.
PubMed: Comparative in vitro cytotoxicity of ethyl acrylate and tripropylene glycol diacrylate to normal human skin and lung cells.
PubMed: A tape-stripping method for measuring dermal exposure to multifunctional acrylates.
PubMed: Workers' dermal exposure to UV-curable acrylates in the furniture and Parquet industry.
PubMed: Occupational dermatitis to ultraviolet-cured acrylic-based inks in computer hard disc manufacturing.
PubMed: Tripropylene glycol diacrylate but not ethyl acrylate induces skin tumors in a twenty-week short-term tumorigenesis study in Tg.AC (v-Ha-ras) mice.
PubMed: Absence of systemic in vivo genotoxicity after dermal exposure to ethyl acrylate and tripropylene glycol diacrylate in Tg.AC (v-Ha-ras) mice.
PubMed: Occupational allergic contact dermatitis caused by photobonded sculptured nails and a review of (meth) acrylates in nail cosmetics.
PubMed: Occupational allergic contact dermatitis caused by epoxy diacrylate in ultraviolet-light-cured paint, and bisphenol A in dental composite resin.
PubMed: Lemna minor membranes affected by adjuvants.
PubMed: Allergic contact dermatitis due to an amino-substituted diacrylate in a UV-cured lacquer.
PubMed: Allergic contact dermatitis to ultra violet cured inks.
PubMed: The sensitizing capacity of multifunctional acrylates in the guinea pig.
PubMed: The pharmacology of the mono methyl ethers of mono-, di-, and tripropylene glycol in the dog with observations on the auricular fibrillation produced by these compounds.
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