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(E)-traumatic acid
(E)-2-dodecenedioic acid

Supplier Sponsors

Name:(E)-dodec-2-enedioic acid
CAS Number: 6402-36-4Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:229-019-4
Nikkaji Web:J5.789D
Beilstein Number:1725762
XlogP3:3.00 (est)
Molecular Weight:228.28820000
Formula:C12 H20 O4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
FEMA Number:4944
FDA:No longer provide for the use of these seven synthetic flavoring substances
Physical Properties:
Appearance:white solid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 165.50 °C. @ 760.00 mm Hg
Boiling Point: 376.00 to 377.00 °C. @ 760.00 mm Hg (est)
Flash Point: 384.00 °F. TCC ( 195.60 °C. ) (est)
logP (o/w): 2.686 (est)
Soluble in:
 water, 229.1 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
BOC Sciences
For experimental / research use only.
Santa Cruz Biotechnology
For experimental / research use only.
Traumatic Acid
Sigma-Aldrich: Sigma
For experimental / research use only.
(E)-Traumatic Acid
For experimental / research use only.
Traumatic Acid >90.0%(GC)
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
natural substances and extractives
Recommendation for (E)-traumatic acid usage levels up to:
 not for fragrance use.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 30
Click here to view publication 30
 average usual ppmaverage maximum ppm
baked goods: 40.00000200.00000
beverages(nonalcoholic): 10.0000050.00000
beverages(alcoholic): 15.0000050.00000
breakfast cereal: 50.00000200.00000
cheese: 50.00000200.00000
chewing gum: 100.00000500.00000
condiments / relishes: 30.00000200.00000
confectionery froastings: 40.00000200.00000
egg products: 40.00000300.00000
fats / oils: 40.00000100.00000
fish products: 50.00000300.00000
frozen dairy: 40.00000300.00000
fruit ices: 15.00000100.00000
gelatins / puddings: 15.00000100.00000
granulated sugar: 40.00000200.00000
gravies: 40.00000200.00000
hard candy: 50.00000300.00000
imitation dairy: 40.00000200.00000
instant coffee / tea: 15.00000100.00000
jams / jellies: 15.00000100.00000
meat products: 50.00000300.00000
milk products: 40.00000100.00000
nut products: 40.00000200.00000
other grains: 50.00000200.00000
poultry: 50.00000300.00000
processed fruits: 50.00000200.00000
processed vegetables: 50.00000300.00000
reconstituted vegetables: 50.00000300.00000
seasonings / flavors: 50.00000300.00000
snack foods: 50.00000300.00000
soft candy: 50.00000300.00000
soups: 50.00000200.00000
sugar substitutes: 30.00000100.00000
sweet sauces: 40.00000100.00000
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5283028
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(E)-dodec-2-enedioic acid
 (E)-dodec-2-enedioic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5283028
Pubchem (sid):134987338
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C16308
HMDB (The Human Metabolome Database):HMDB00933
Export Tariff Code:2917.19.7050
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 pea pod
Search Trop Picture
(E)-dodec-2-ene dioic acid
(2E)-dodec-2-enedioic acid
(E)-dodec-2-enedioic acid
(E)-2-dodecene dioic acid
(2E)-2-dodecenedioic acid
(E)-2-dodecenedioic acid
trans-2-dodecenedioic acid
2-dodecenedioic acid, (2E)-
2-dodecenedioic acid, trans-
trans-traumatic acid


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PubMed:Hydroperoxide lyase cascade in pea seedlings: Non-volatile oxylipins and their age and stress dependent alterations.
PubMed:The effect of traumatic acid on tyrosine phosphorylation of proteins in pea seedlings.
PubMed:A fatty acid alpha-ketol, a product of the plant lipoxygenase pathway, is oxidized to 3(Z)-dodecendioic acid by a bacterial monooxygenase.
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PubMed:Identification of Traumatin, a Wound Hormone, as 12-Oxo-trans-10-dodecenoic Acid.
PubMed:Suberization: inhibition by washing and stimulation by abscisic Acid in potato disks and tissue culture.
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PubMed:[Filatov's tissue therapy. II. The detection of a wound hormone effect of Filatov's preserved tissues, aloe and of cod liver oil as tested on traumatic acid-bean test in Petri dish].
PubMed:Traumatic Acid and Thiamin as Growth Factors for Algae.
None found
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