PubMed:Evaluation of co-solvent fraction, pressure and temperature effects in analytical and preparative supercritical fluid chromatography. |
PubMed:Switchable enantioseparation based on macromolecular memory of a helical polyacetylene in the solid state. |
PubMed:Three versus five micrometer chlorinated polysaccharide-based packings in chiral capillary electrochromatography: efficiency and precision evaluation. |
PubMed:Experiment and modeling for the separation of trans-stilbene oxide enantiomers on Chiralcel OD preparative column. |
PubMed:Cloning and characterization of a microsomal epoxide hydrolase from Heliothis virescens. |
PubMed:Enantioselective ultra-high and high performance liquid chromatography: a comparative study of columns based on the Whelk-O1 selector. |
PubMed:Evaluation of injection conditions for preparative supercritical fluid chromatography. |
PubMed:Controlled synthesis and chiral recognition of immobilized cellulose and amylose tris(cyclohexylcarbamate)s/3-(triethoxysilyl)propylcarbamates as chiral packing materials for high-performance liquid chromatography. |
PubMed:Determinants of reactivity and selectivity in soluble epoxide hydrolase from quantum mechanics/molecular mechanics modeling. |
PubMed:A test to determine the nature and presence of the memory effect columns packed with the amylose tris(3,5-dimethylphenylcarbamate) stationary phase. |
PubMed:The influence of the memory effect on preparative separations using the amylose tris(3,5-dimethylphenylcarbamate) stationary phase. |
PubMed:Antiviral stilbene 1,2-diamines prevent initiation of hepatitis C virus RNA replication at the outset of infection. |
PubMed:The influence of water on the memory effect of the amylose tris(3,5-dimethylphenyl carbamate) stationary phase. |
PubMed:Aerobic methylcyclohexane-promoted epoxidation of stilbene over gold nanoparticles supported on Gd-doped titania. |
PubMed:Modular, active, and robust Lewis acid catalysts supported on a metal-organic framework. |
PubMed:Characterizing the Memory Effect on the amylose tris(3,5-dimethylphenyl) carbamate stationary phase. |
PubMed:Substrate-dependent hysteretic behavior in StEH1-catalyzed hydrolysis of styrene oxide derivatives. |
PubMed:Biomimetic iron-catalyzed asymmetric epoxidation of aromatic alkenes by using hydrogen peroxide. |
PubMed:In vitro evaluation of the cytotoxic and anti-proliferative properties of resveratrol and several of its analogs. |
PubMed:Removal of distal protein-water hydrogen bonds in a plant epoxide hydrolase increases catalytic turnover but decreases thermostability. |
PubMed:Preparation of novel beta-cyclodextrin chiral stationary phase based on click chemistry. |
PubMed:Chiral recyclable dimeric and polymeric Cr(III) salen complexes catalyzed aminolytic kinetic resolution of trans-aromatic epoxides under microwave irradiation. |
PubMed:Active site of epoxide hydrolases revisited: a noncanonical residue in potato StEH1 promotes both formation and breakdown of the alkylenzyme intermediate. |
PubMed:Direct synthesis of well-ordered and unusually reactive MnSBA-15 mesoporous molecular sieves with high manganese content. |
PubMed:An evaluation of four commercial HPLC chiral detectors: a comparison of three polarimeters and a circular dichroism detector. |
PubMed:Induction of genes for metabolism and transport by trans-stilbene oxide in livers of Sprague-Dawley and Wistar-Kyoto rats. |
PubMed:trans-Stilbene oxide induces expression of genes involved in metabolism and transport in mouse liver via CAR and Nrf2 transcription factors. |
PubMed:Implications for an ionized alkyl-enzyme intermediate during StEH1-catalyzed trans-stilbene oxide hydrolysis. |
PubMed:Catalysis of potato epoxide hydrolase, StEH1. |
PubMed:Design of sulfides with a locked conformation as promoters of catalytic and asymmetric sulfonium ylide epoxidation. |
PubMed:[Preparation of covalently bonded cellulose tris (4-methylbenzoate) derivative chiral stationary phases through a polymerization reaction]. |
PubMed:Regio- and stereoselective ring opening of 2,3-diaryl oxiranes by LiBr/Amberlyst 15: a new stereocontrolled access to 1,2-diaryl-2-bromo alcohols. |
PubMed:Parallel mechanistic studies on the counterion effect of manganese salen and porphyrin complexes on olefin epoxidation by iodosylarenes. |
PubMed:Separation of racemic trans-stilbene oxide by sub-/supercritical fluid chromatography. |
PubMed:Characterization and cDNA cloning of a clofibrate-inducible microsomal epoxide hydrolase in Drosophila melanogaster. |
PubMed:Induction of multidrug resistance protein 3 (mrp3) in vivo is independent of constitutive androstane receptor. |
PubMed:Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites. |
PubMed:Polymorphisms in human soluble epoxide hydrolase. |
PubMed:Single route to chiral syn- and anti-2-amino-1,2-diphenylethanols via a new stereodivergent opening of trans-1,2-diphenyloxirane. |
PubMed:Identification of residues in glutathione transferase capable of driving functional diversification in evolution. A novel approach to protein redesign. |
PubMed:Stabilization of nontoxic PVC formulation for gamma irradiation sterilization, II. Effect of antioxidants. |
PubMed:Brassica napus soluble epoxide hydrolase (BNSEH1). |
PubMed:Overexpression of Arabidopsis thaliana soluble epoxide hydrolase 1 in Pichia pastoris and characterisation of the recombinant enzyme. |
PubMed:Anionic ligand effect on the nature of epoxidizing intermediates in iron porphyrin complex-catalyzed epoxidation reactions. |
PubMed:Separation of enantiomers by nanoliquid chromatography and capillary electrochromatography using a bonded cellulose trisphenylcarbamate stationary phase. |
PubMed:Loss of glutathione S-transferase (GST) mu phenotype in colorectal adenocarcinomas from patients with a GSTM1 positive genotype. |
PubMed:Trans-stilbene oxide-induced sister chromatid exchange in cultured human lymphocytes: influence of GSTM1 and GSTT1 genotypes. |
PubMed:Inhibition of platelet function by GSTM1-null human peripheral lymphocytes exposed to benzo(a)pyrene-induced challenge. |
PubMed:Evaluation of fish models of soluble epoxide hydrolase inhibition. |
PubMed:First success of catalytic epoxidation of olefins by an electron-rich iron(III) porphyrin complex and H2O2: imidazole effect on the activation of H2O2 by iron porphyrin complexes in aprotic solvent. |
PubMed:Modulation of human glutathione S-transferases by botanically defined vegetable diets. |
PubMed:Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers. |
PubMed:Metabolic activation of the proestrogens trans-stilbene and trans-stilbene oxide by rat liver microsomes. |
PubMed:Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms. |
PubMed:Reductive metabolism of stilbene oxide and styrene oxide to the olefins in rats. |
PubMed:Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the glutathione S-transferase A5 and P1 subunits, and NAD(P)H:quinone oxidoreductase in rat liver. |
PubMed:Glutathione S-transferase-catalyzed conjugation of bioactivated aflatoxin B(1) in human lung: differential cellular distribution and lack of significance of the GSTM1 genetic polymorphism. |
PubMed:Potent urea and carbamate inhibitors of soluble epoxide hydrolases. |
PubMed:Decreased expression of glutathione S-transferase M1 in HPV16-transfected human cervical keratinocytes in culture. |
PubMed:Cloning and expression of a novel juvenile hormone-metabolizing epoxide hydrolase during larval-pupal metamorphosis of the cabbage looper, Trichoplusia ni. |
PubMed:Regulation of rat glutathione S-transferase A5 by cancer chemopreventive agents: mechanisms of inducible resistance to aflatoxin B1. |
PubMed:Regulation of rat olfactory glutathione S-transferase expression. Investigation of sex differences, induction, and ontogenesis. |
PubMed:Methods for purification of glutathione transferases in the earthworm genus Eisenia, and their characterization. |
PubMed:Suppressed expression of phenobarbital-inducible hepatic cytochrome P-450s in Eisai-hyperbilirubinuria rats (EHBR/Eis). |
PubMed:Dioxomolybdenum(VI) Complexes with New Enantiomerically Pure Amino Diol Ligands. |
PubMed:Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase. |
PubMed:Development of an in situ toxicity assay system using recombinant baculoviruses. |
PubMed:Radiation effects on polypropylene for sterilization. |
PubMed:Glutathione S-transferases in the Japanese quail: tissue distribution and purification of the liver isozymes. |
PubMed:Induction of metallothionein synthesis by glutathione depletion after trans- and cis-stilbene oxide administration in rats. |
PubMed:Improved radiolabeled substrates for soluble epoxide hydrolase. |
PubMed:Human leukocyte glutathione S-transferase isozyme (class mu) and susceptibility to smoking-related cancers. |
PubMed:Human variability in hepatic glutathione S-transferase-mediated conjugation of aflatoxin B1-epoxide and other substrates. |
PubMed:Evaluation of the generation of genotoxic and cytotoxic metabolites of benzo[a]pyrene, aflatoxin B1, naphthalene and tamoxifen using human liver microsomes and human lymphocytes. |
PubMed:Computational studies on chiral discrimination mechanism of cellulose trisphenylcarbamate. |
PubMed:Induction of rat liver microsomal epoxide hydrolase by its endogenous substrate 16 alpha, 17 alpha-epoxyestra-1,3,5-trien-3-ol. |
PubMed:A glutathione depletion selectively imposed on mu glutathione S-transferase overproducing cells increases nitrogen mustard toxicity. |
PubMed:Correlation of the response to nitroglycerin in rabbit aorta with the activity of the mu class glutathione S-transferase. |
PubMed:Microsomal glutathione S-transferase (GST) isozymes in Aspergillus ochraceus TS: induction by 3-methylcholanthrene. |
PubMed:Glutathione S-transferase M1 and its variants A and B as host factors of bladder cancer susceptibility: a case-control study. |
PubMed:The expression of glutathione transferase mu in patients with inflammatory bowel disease. |
PubMed:Characterization of an Arabidopsis cDNA for a soluble epoxide hydrolase gene that is inducible by auxin and water stress. |
PubMed:NADPH cytochrome P-450 oxidoreductase gene: identification and characterization of the promoter region. |
PubMed:Epoxide reductase activity of mammalian liver cytosols and aldehyde oxidase. |
PubMed:Photoaffinity labeling of Arabidopsis thaliana plasma membrane vesicles by 5-azido-[7-3H]indole-3-acetic acid: identification of a glutathione S-transferase. |
PubMed:Affinity labeling of glutathione S-transferase, isozyme 4-4, by 4-(fluorosulfonyl)benzoic acid reveals Tyr115 to be an important determinant of xenobiotic substrate specificity. |
PubMed:Glutathione transferase activity in human vessels and in cultured arterial smooth muscle cells. |
PubMed:Some substrates and inhibitors of cytosolic epoxide hydrolase induce sister-chromatid exchanges in mammalian cells, but do not induce gene mutations in Salmonella typhimurium and V79 cells. |
PubMed:Chiral HPLC versus chiral SFC: evaluation of long-term stability and selectivity of Chiralcel OD using various eluents. |
PubMed:Measurement and characterization of the denitrosation of tauromustine and related nitrosoureas by glutathione transferases in liver cytosol from various species. |
PubMed:Cloning and characterization of the major hepatic glutathione S-transferase from a marine teleost flatfish, the plaice (Pleuronectes platessa), with structural similarities to plant, insect and mammalian Theta class isoenzymes. |
PubMed:The glutathione S-transferase mu polymorphism as a marker for susceptibility to lung carcinoma. |
PubMed:Purification and characterization of class mu glutathione S-transferase isozymes from rabbit hepatic tissue. |
PubMed:Genotype and phenotype of glutathione S-transferase class mu isoenzymes mu and psi in lung cancer patients and controls. |
PubMed:Effect of P-450 inducers on biliary excretion of glutathione and its hydrolysis products. Correlation between hepatic gamma-glutamyltranspeptidase activity and the proportion of glutathione hydrolysis products in bile. |
PubMed:Inhibition of human and murine cytosolic epoxide hydrolase by group-selective reagents. |
PubMed:Effects of selenium deficiency on xenobiotic-metabolizing and other enzymes in rat liver. |
PubMed:Effect of inducers on the activity of glutathione S-transferase and other enzymes of the glutathione pathway in cultured human keratinocytes. |
PubMed:Genetic monitoring of human polymorphic cancer susceptibility genes by polymerase chain reaction: application to glutathione transferase mu. |
PubMed:Effects of microsomal enzyme inducers upon UDP-glucuronic acid concentration and UDP-glucuronosyltransferase activity in the rat intestine and liver. |
PubMed:Oxygen transfer reactions by synthetic analogues of iron-bleomycin. |
PubMed:Human fibroblasts lacking trans-stilbene oxide active glutathione transferase exhibit increased cell death when exposed to polycyclic aromatic hydrocarbons. |
PubMed:Mutant genes of cytochrome P-450IID6, glutathione S-transferase class Mu, and arylamine N-acetyltransferase in lung cancer patients. |
PubMed:Cigarette smoke inhibits cytosolic but not microsomal epoxide hydrolase of human lung. |
PubMed:Correlation between trans-stilbene oxide-glutathione conjugation activity and the deletion mutation in the glutathione S-transferase class mu gene detected by polymerase chain reaction. |
PubMed:Glutathione S-transferase mu in human lymphocyte and liver: role in modulating formation of carcinogen-derived DNA adducts. |
PubMed:Glutathione S-transferase mu locus: use of genotyping and phenotyping assays to assess association with lung cancer susceptibility. |
PubMed:Altered metabolic hormones, impaired nitrogen retention, and hepatotoxicosis in lambs fed Kochia scoparia hay. |
PubMed:Nutritional and toxicological evaluations of kochia hay (Kochia scoparia) fed to lambs. |
PubMed:Effect of chemicals on glutathione peroxidase of chick liver. |
PubMed:Effects of environmentally encountered epoxides on mouse liver epoxide-metabolizing enzymes. |
PubMed:Purification and characterization of an epoxide hydrolase from the peroxisomal fraction of mouse liver. |
PubMed:Comparative studies of the effects of stilbene compounds on hepatic ornithine decarboxylase and S-adenosylmethionine decarboxylase induction in rats. |
PubMed:Expression of arylhydrocarbon hydroxylase, epoxide hydrolases, glutathione S-transferase and UDP-glucuronosyltransferases in H5-6 hepatoma cells. |
PubMed:An epoxysuccinic acid derivative(loxistatin)-induced hepatic injury in rats and hamsters. |
PubMed:Quantification of human hepatic glutathione S-transferases. |
PubMed:Rat and human liver cytosolic epoxide hydrolases: evidence for multiple forms at level of protein and mRNA. |
PubMed:Lack of glutathione transferase activity in intermittent claudication. |
PubMed:Human glutathione S-transferase deficiency as a marker of susceptibility to epoxide-induced cytogenetic damage. |
PubMed:Production of monospecific antiserum to a cytosolic epoxide hydrolase from human liver. |
PubMed:Isoenzyme(s) of glutathione transferase (class Mu) as a marker for the susceptibility to lung cancer: a follow up study. |
PubMed:Increase in the amount of glutathione transferase 4-4 in the rat adrenal gland after hypophysectomy and down-regulation by subsequent treatment with adrenocorticotrophic hormone. |
PubMed:Effects of inducers of drug metabolism on basic hepatic forms of mouse glutathione transferase. |
PubMed:Characterization of distinct forms of cytochromes P-450, epoxide metabolizing enzymes and UDP-glucuronosyltransferases in rat skin. |
PubMed:Identification of the trans-stilbene oxide-active glutathione transferase in human mononuclear leukocytes and in liver as GST1. |
PubMed:Microsomal and cytosolic epoxide hydrolase and glutathione S-transferase activities in the gill, liver, and kidney of the rainbow trout, Salmo gairdneri. Baseline levels and optimization of assay conditions. |
PubMed:Inducibility of glutathione S-transferases in hamsters. |
PubMed:Immunochemical comparison of human and rhesus monkey liver microsomal and the hepatocellular carcinoma-induced human serum epoxide hydrolases (preneoplastic antigens): basis for an enzyme-linked immunoabsorbent assay. |
PubMed:Rapid [14C]heptachlor clearance from body stores of ovines: ingested mineral oil and parenteral trans-stilbene oxide lack effects. |
PubMed:Glutathione transferases in rat hepatoma cells. Effects of ascites cells on the isoenzyme pattern in liver and induction of glutathione transferases in the tumour cells. |
PubMed:Similarities between catalase and cytosolic epoxide hydrolase. |
PubMed:Selective inhibition of cytosolic epoxide hydrolase activity in vitro by compounds that inhibit catalase. |
PubMed:Comparative induction of drug-metabolizing enzymes by hypolipidaemic compounds. |
PubMed:Valpromide is a poor inhibitor of the cytosolic epoxide hydrolase. |
PubMed:Antimutagenesis by shift in monooxygenase isoenzymes and induction of epoxide hydrolase. |
PubMed:[Comparative characteristics of microsomal epoxide hydrolase in the rat liver and small intestine mucosa]. |
PubMed:Organ distribution of epoxide hydrolases in cytosolic and microsomal fractions of normal and nafenopin-treated male DBA/2 mice. |
PubMed:Continuous spectrophotometric assays for cytosolic epoxide hydrolase. |
PubMed:Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion. |
PubMed:Human liver cytosolic epoxide hydrolases. |
PubMed:Purification and characterization of rat-liver cytosolic epoxide hydrolase. |
PubMed:Epoxide-metabolizing enzymes in mammary gland and liver from BALB/c mice and effects of inducers on enzyme activity. |
PubMed:Cytosolic epoxide hydrolase. |
PubMed:Cytosolic epoxide hydrolase in humans: development and tissue distribution. |
PubMed:The genetic variation and the expression of human glutathione transferase mu. |
PubMed:Biological effects in a chemical factory with mutagenic exposure. II. Analysis of unscheduled DNA synthesis and adenosine diphosphate ribosyl transferase, epoxide hydrolase, and glutathione transferase in resting mononuclear leukocytes. |
PubMed:Oxene transfer, electron abstraction, and cooxidation in the epoxidation of stilbene and 7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene by hemoglobin. |
PubMed:Hepatic epoxide hydrolase activities and their induction by clofibrate and diethylhexylphthalate in various strains of mice. |
PubMed:Differential induction of cytochrome P-450 by the enantiomers of trans-stilbene oxide. |
PubMed:Metabolism of tridiphane (2-(3,5-dichlorophenyl)-2(2,2,2-trichloroethyl)oxirane) by hepatic epoxide hydrolases and glutathione S-transferases in mouse. |
PubMed:Purification of microsomal epoxide hydrolase from liver of rhesus monkey: partial separation of cis- and trans-stilbene oxide hydrolase. |
PubMed:The trans-stilbene oxide-active glutathione transferase in human mononuclear leucocytes is identical with the hepatic glutathione transferase mu. |
PubMed:Comparison of the sex and subcellular distributions, catalytic and immunochemical reactivities of hepatic epoxide hydrolases in seven mammalian species. |
PubMed:The effect of tridiphane (2-(3,5-dichlorophenyl)-2-(2,2,2-trichloroethyl)oxirane) on hepatic epoxide-metabolizing enzymes: indications of peroxisome proliferation. |
PubMed:Inhibition of epoxide hydrolases and glutathione S-transferases by 2-, 3-, and 4-substituted derivatives of 4'-phenylchalcone and its oxide. |
PubMed:Dibenz [a,j]acridine: distributions of metabolites formed by liver and lung microsomes from control and pretreated rats. |
PubMed:Stereoselectivity and enantioselectivity of glutathione S-transferase toward stilbene oxide substrates. |
PubMed:Hepatic levels of cytosolic, microsomal and 'mitochondrial' epoxide hydrolases and other drug-metabolizing enzymes after treatment of mice with various xenobiotics and endogenous compounds. |
PubMed:DT-diaphorase-catalyzed two-electron reduction of quinone epoxides. |
PubMed:Effect of microsomal enzyme inducers and inhibitors on the toxicity of tunicamycin and corynetoxin, the causal agent of annual ryegrass toxicity. |
PubMed:cis- and trans-1,2-diphenylaziridines: induction of xenobiotic-metabolizing enzymes in rat liver and mutagenicity in Salmonella typhimurium. |
PubMed:Immunochemical characterization of human lung epoxide hydrolases. |
PubMed:Distribution and inducibility of cytosolic epoxide hydrolase in male Sprague-Dawley rats. |
PubMed:Characterization of multiple epoxide hydrolase activities in mouse liver nuclear envelope. |
PubMed:Substrate-selective induction of rabbit hepatic UDP-glucuronyltransferases by ethanol and other xenobiotics. |
PubMed:Oxidative microsomal metabolism of 1-nitropyrene and DNA-binding of oxidized metabolites following nitroreduction. |
PubMed:Epoxide hydrolysis in the cytosol of rat liver, kidney, and testis. Measurement in the presence of glutathione and the effect of dietary clofibrate. |
PubMed:Suppression of glutathione S-transferases in rat seminal vesicles or pituitary glands. |
PubMed:Distribution and nature of epoxide hydrolase activity in subcellular organelles of mouse liver. |
PubMed:Selective inhibition and selective induction of multiple microsomal epoxide hydrolases. |
PubMed:Multiple epoxide hydrolases in human lung. |
PubMed:Effect of aging on testicular epoxide hydrolase and glutathione-S-transferase activities in mice. |
PubMed:Demonstration of cell sidedness in hepatic transfer of morphine and morphine glucuronide in the rat. |
PubMed:Comparison of crude and affinity purified cytosolic epoxide hydrolases from hepatic tissue of control and clofibrate-fed mice. |
PubMed:Rat cytosolic epoxide hydrolase. |
PubMed:Differential regulation of hepatic glutathione transferase and glutathione peroxidase activities in the rat. |
PubMed:Enzymatic hydration of leukotriene A4. Purification and characterization of a novel epoxide hydrolase from human erythrocytes. |
PubMed:Inhibition of epoxide metabolism by alpha,beta-epoxyketones and isosteric analogs. |
PubMed:Metabolism of benzo(a)pyrene by subcellular fractions of rat liver: evidence for similar patterns of cytochrome P-450 in rough and smooth endoplasmic reticulum but not in nuclei and plasma membrane. |
PubMed:Properties of liver microsomal cholesterol 5,6-oxide hydrolase. |
PubMed:Hereditary interindividual differences in the glutathione transferase activity towards trans-stilbene oxide in resting human mononuclear leukocytes are due to a particular isozyme(s). |
PubMed:Properties of cytosolic epoxide hydrolase purified from the liver of untreated and clofibrate-treated mice. Characterization of optimal assay conditions, substrate specificity and effects of modulators on the catalytic activity. |
PubMed:Effect of dietary clofibrate on epoxide hydrolase activity in tissues of mice. |
PubMed:Role of glutathione and hepatic glutathione S-transferase in the biliary excretion of methyl mercury, cadmium and zinc: a study with enzyme inducers and glutathione depletors. |
PubMed:Induction of epoxide hydrolase in cultured rat hepatocytes and hepatoma cell lines. |
PubMed:Effects of mixed-function oxidase modifiers on neurotoxicity of acrylamide in rats. |
PubMed:Cyclopropyl oxiranes: reversible inhibitors of cytosolic and microsomal epoxide hydrolases. |
PubMed:Interindividual variations in the activities of cytosolic and microsomal epoxide hydrolase in human liver. |
PubMed:The dependence of biliary methylmercury secretion on liver GSH and ligandin. |
PubMed:The hereditary transmission of high glutathione transferase activity towards trans-stilbene oxide in human mononuclear leukocytes. |
PubMed:Stereoselective glucuronidation as a probe of induced forms of UDP-glucuronyltransferase in rabbits. |
PubMed:Age-development and inducibility of hepatic glutathione S-transferase activities in mice, rats, rabbits and guinea-pigs. |
PubMed:Glutathione S-transferase activity during pregnancy in the mouse: effects of trans-stilbene oxide pretreatment. |
PubMed:Characterization of soluble glutathione transferase activity in resting mononuclear leukocytes from human blood. |
PubMed:Ethanol and isoniazid induce a hepatic microsomal cytochrome P-450-dependent activity with similar properties towards substrate and inhibitors and different properties from those induced by classical inducers. |
PubMed:Measurement and characterization of membrane-bound and soluble epoxide hydrolase activities in resting mononuclear leukocytes from human blood. |
PubMed:Purification and characterization of the major microsomal cytochrome P-450 form induced by trans-stilbene oxide in rat liver. |
PubMed:Immunological similarity of epoxide hydrolase activity in the mitochondrial and cytosolic fractions of mouse liver. |
PubMed:A mechanism for epoxidation of cholesterol by hepatic microsomal lipid hydroperoxides. |
PubMed:Characterization, localization and regulation of a novel phenobarbital-inducible form of cytochrome P450, compared with three further P450-isoenzymes, NADPH P450-reductase, glutathione transferases and microsomal epoxide hydrolase. |
PubMed:Characteristics of renal UDP-glucuronyltransferase. |
PubMed:Rat liver DT-diaphorase: regulation of functional mRNA levels by 3-methylcholanthrene, trans-stilbene oxide, and phenobarbital. |
PubMed:Induction of cytosolic glutathione transferase and microsomal epoxide hydrolase activities in extrahepatic organs of the rat by phenobarbital, 3-methylcholanthrene and trans-stilbene oxide. |
PubMed:Induction of xenobiotic-metabolizing enzymes by trans-stilbene oxide and 2-acetylaminofluorene: observations on enzyme induction by drugs. |
PubMed:Effect of dietary trans-stilbene oxide on hepatic and renal drug-metabolizing enzyme activities and bromobenzene-induced toxicity in male Sprague-Dawley rats. |
PubMed:Human fetal liver cultures: basal activities and inducibility of epoxide hydrolases and aryl hydrocarbon hydroxylase. |
PubMed:Identification and characterization of a new epoxide hydrolase from mouse liver microsomes. |
PubMed:Differential induction of cytosolic epoxide hydrolase, microsomal epoxide hydrolase, and glutathione S-transferase activities. |
PubMed:Expression of microsomal and cytosolic epoxide hydrolases in cultured rat hepatocytes and hepatoma cell lines. |
PubMed:Nonadditive effects of combined in vivo hepatic microsomal enzyme inducers in the Wistar rat. |
PubMed:Epoxide hydrolase activity in isolated peroxisomes of mouse liver. |
PubMed:Effects of phenobarbital, trans-stilbene oxide, and 3-methylcholanthrene on epoxide hydrolase within centrilobular, midzonal, and periportal regions of rat liver. |
PubMed:Microsomal epoxide hydrolase in different rat strains. |
PubMed:Purification of mouse liver cytosolic epoxide hydrolase. |
PubMed:Identification and partial purification of hamster microsomal cytochrome P-450 isoenzymes. |
PubMed:Comparison of trans-stilbene oxide, phenobarbital and 3-methylcholanthrene as inducers of steroid metabolism by the rat liver microsomal cytochrome P-450 system. |
PubMed:Variations in induction of drug-metabolizing enzymes by trans-Stilbene oxide in rodent species. |
PubMed:Species differences in cytochromes P-450 and epoxide hydrolase: comparisons of xenobiotic-induced hepatic microsomal polypeptides in hamsters and rats. |
PubMed:Identification of the isozymes of glutathione transferase induced by trans-stilbene oxide. |
PubMed:Chemically-induced alteration of UDP-glucuronic acid concentration in rat liver. |
PubMed:Characterization of the microsomal cytochrome P-450 species induced in rat liver by trans-stilbene oxide. |
PubMed:Polypeptide patterns of hepatic microsomes from Long-Evans rats treated with different xenobiotics. |
PubMed:Purification of human liver cytosolic epoxide hydrolase and comparison to the microsomal enzyme. |
PubMed:Binding of metyrapone to dithionite-reduced cytochrome P-450 from rats treated with xenobiotics. |
PubMed:Trans-stilbene oxide administration increased hepatic glucuronidation of morphine but decreased biliary excretion of morphine glucuronide in rats. |
PubMed:Effects of trans-stilbene oxide treatment on biliary excretion of xenobiotics in the rat. |
PubMed:Oxygen transfer from bleomycin-metal complexes. |
PubMed:Endogenous role of microsomal epoxide hydrolase. Ontogenesis, induction inhibition, tissue distribution, immunological behaviour and purification of microsomal epoxide hydrolase with 16 alpha, 17 alpha-epoxyandrostene-3-one as substrate. |
PubMed:Spectrophotometric assay for mammalian cytosolic epoxide hydrolase using trans-stilbene oxide as the substrate. |
PubMed:The effect of trans-stilbene oxide and other structurally related inducers of drug-metabolizing enzymes on the pentose phosphate pathway and other enzymes of carbohydrate metabolism. |
PubMed:The effect of trans-stilbene oxide and other structurally related inducers of drug-metabolizing enzymes on glucuronidation. |
PubMed:Role of ligandin as a binding protein and as an enzyme in the biliary excretion of sulfobromophthalein. |
PubMed:Differential induction of rat liver microsomal UDP-glucuronosyltransferase activites by various inducing agents. |
PubMed:Differential inducibility of nuclear envelope epoxide hydratase by trans-stilbene oxide and phenobarbital. |
PubMed:Rat glutathione S-transferase. Cloning of double-stranded cDNA and induction of its mRNA. |
PubMed:Soluble glutathione S-transferases from rat testes: isoenzyme pattern and lack of inducibility by drug metabolizing enzyme inducers. |
PubMed:Effects of drug-metabolizing enzyme inducers on cephaloridine toxicity in Fischer 344 rats. |
PubMed:The nuclear envelope as a site of glucuronyltransferase in rat liver: properties of and effect of inducers on enzyme activity. |
PubMed:Effect of inducers of drug-metabolizing enzymes on glutathione reductase and glutathione peroxidase in rat liver. |
PubMed:Responses of the hepatic enzymes of a teleost fish to trans-stilbene oxide treatment. |
PubMed:Cloning of epoxide hydratase complementary DNA. |
PubMed:A comparative study of benzo[a]pyrene hydroxylase and epoxide hydrolase derived from isolated rat hepatic nuclei and microsomes. |
PubMed:Characterization of the induction of drug-metabolizing enzymes by 2-acetylaminofluorene. |
PubMed:Induction of drug-metabolizing systems and related enzymes with metabolites and structural analogues of stilbene. |
PubMed:Changes in the matabolism of steroid hormones by the rat liver cytochrome P-450 system after induction with trans-stilbene oxide. |
PubMed:The effects of modulation of microsomal epoxide hydrolase activity on microsome-catalyzed activation of benzo[alpha]pyrene and its covalent binding to DNA. |
PubMed:Induction of drug-metabolizing enzymes and toxicity of trans-stilbene oxide in rat liver and kidney. |
PubMed:Modulation of the covalent binding of aryl hydrocarbon metabolites to DNA in vitro after treatment of rats and mice with trans-stilbene oxide. |
PubMed:Benzil, a potent activator of microsomal epoxide hydrolase in vitro. |
PubMed:Sex and age dependence of the "selective" induction of rat hepatic microsomal epoxide hydratase following trans-stilbene oxide, l-alpha-acetylmethadol, or phenobarbital treatment. |
PubMed:The proliferation of hepatocytes and the lipid composition of the endoplasmic reticulum after induction of drug-metabolizing enzymes with trans-stilbene oxide. |
PubMed:Induction of glutathione S-transferases A, B and C in rat liver cytosol by trans-stilbene oxide. |
PubMed:Induction of hepatic cytosolic DT diaphorase in rats treated with trans-stilbene oxide. |
PubMed:Epoxide hydrolase activity in native and in mitogen-stimulated lymphocytes of various human donors. |
PubMed:Comparison of aryl hydrocarbon hydroxylase and epoxide hydratase. Induction in primary fetal rat liver cell culture. |
PubMed:Specificity of mouse liver cytosolic epoxide hydrolase for K-region epoxides derived from polycyclic aromatic hydrocarbons. |
PubMed:Characterization of rat-liver microsomal glutathione S-transferase activity. |
PubMed:Increased activity of hepatic UDP-glucose dehydrogenase after treatment of rats with trans-stilbene oxide. |
PubMed:Characterization of the cytochrome P-450 species induced by trans-stilbene oxide. |
PubMed:Dose-response relationship of rat aryl hydrocarbon hydroxylase and epoxide hydratase induction. |
PubMed:The epoxide hydratase inducer trans-stilbene oxide shifts the metabolic epoxidation of benzo(a)pyrene from the bay- to the K-region and reduces its mutagenicity. |
PubMed:Species and organ specificity of the trans-stilbene oxide induced effects on epoxide hydratase and benzo(a)pyrene monooxygenase activity in rodents. |
PubMed:Organ specificity of induction of activating and inactivating enzymes by cigarette smoke and cigarette smoke condensate. |
PubMed:trans-Stilbene oxide: a new inducer of rat liver microsomal UDP-glucuronyltransferase. |
PubMed:trans-Stilbene oxide: an inducer of rat hepatic microsomal and nuclear epoxide hydrase and mixed-function oxidase activities. |
PubMed:Trans-stilbene oxide: a selective inducer of rat liver epoxide hydratase. |