Category:indirect food additives: adhesives and components of coatings
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Assay: | 95.00 to 100.00
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Food Chemicals Codex Listed: | No |
Specific Gravity: | 1.22500 @ 25.00 °C.
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Flash Point: | 250.00 °F. TCC ( 121.11 °C. )
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Soluble in: |
| water, 37.57 mg/L @ 25 °C (est) |
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
Preferred SDS: View |
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
oral-bird - wild LD50 100 mg/kg Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
intravenous-mouse LD50 56 mg/kg U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#07807
oral-rat LD50 5800 mg/kg GASTROINTESTINAL: OTHER CHANGES AMA Archives of Industrial Health. Vol. 15, Pg. 324, 1957.
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Dermal Toxicity: |
skin-rabbit LD50 > 16 mL/kg Union Carbide Data Sheet. Vol. 3/8/1973
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Inhalation Toxicity: |
inhalation-guinea pig LC50 13 ppm/4H LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI
LUNGS, THORAX, OR RESPIRATION: PLEURAL EFFUSION
LUNGS, THORAX, OR RESPIRATION: CHANGES IN PULMONARY VASCULAR RESISTANCE American Industrial Hygiene Association Journal. Vol. 23, Pg. 447, 1962.
inhalation-human TCLo 20 ppb/2Y LUNGS, THORAX, OR RESPIRATION: COUGH
LUNGS, THORAX, OR RESPIRATION: SPUTUM Proceedings of the Royal Society of Medicine. Vol. 63, Pg. 372, 1970.
inhalation-human TCLo 80 ppb LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE
SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION Archiv fuer Toxikologie. Vol. 19, Pg. 364, 1962.
inhalation-human TCLo 500 ppb LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION Journal of Occupational Medicine. Vol. 1, Pg. 448, 1959.
inhalation-mouse LC50 10 ppm/4H LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI
LUNGS, THORAX, OR RESPIRATION: CHANGES IN PULMONARY VASCULAR RESISTANCE American Industrial Hygiene Association Journal. Vol. 23, Pg. 447, 1962.
inhalation-rabbit LC50 11 ppm/4H BEHAVIORAL: EXCITEMENT
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS American Industrial Hygiene Association Journal. Vol. 23, Pg. 447, 1962.
inhalation-rat LC50 14 ppm/4H SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: EXCITEMENT American Industrial Hygiene Association Journal. Vol. 23, Pg. 447, 1962.
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Safety in Use Information:
Category: | indirect food additives: adhesives and components of coatings |
Recommendation for tolylene 2,4-diisocyanate usage levels up to: | | not for fragrance use.
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Recommendation for tolylene 2,4-diisocyanate flavor usage levels up to: |
| not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| benzene, 2,4-diisocyanato-1-methyl- | iso | cyanic acid, 4-methyl-m-phenylene ester (8CI) | 2,4- | diisocyanato-1-methylbenzene | 2,4- | diisocyanato-1-methylbenzene [toluenediisocyanates] | | hylene T | 4- | methyl-m-phenylene diisocyanate | | nacconate IOO | 2,4- | toluene diisocyanate |
Articles:
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