EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

tin(ii) fluoride
difluoro-lamda2-stannane

Supplier Sponsors

Name:difluorotin
CAS Number: 7783-47-3Picture of molecule3D/inchi
Other(deleted CASRN):12324-56-0
ECHA EINECS - REACH Pre-Reg:231-999-3
FDA UNII: 3FTR44B32Q
MDL:MFCD00042540
Molecular Weight:156.70680640
Formula:F2 Sn
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:cosmetic agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:white crystalline solid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:4.57000 @ 25.00 °C.
Boiling Point: 19.50 °C. @ 760.00 mm Hg (est)
Vapor Pressure:922.000000 mmHg @ 25.00 °C. (est)
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -1.357 (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antiplaque agents
oral care agents
 
Suppliers:
American International Chemical, LLC.
STANNOUS FLUORIDE
Penta International
STANNOUS FLUORIDE USP
Sigma-Aldrich: Aldrich
For experimental / research use only.
Tin(II) fluoride 99%
sds
Universal Preserv-A-Chem Inc.
STANNOUS FLUORIDE USP
Odor: characteristic
Use: It is used as an ingredient in toothpastes that are typically more expensive than those that use sodium fluoride. Stannous fluoride converts the calcium mineral apatite into fluorapatite, which makes tooth enamel more resistant to bacteria-generated acid attacks. In toothpastes containing calcium minerals, sodium fluoride becomes ineffective over time, while stannous fluoride remains effective in strengthening tooth enamel.
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 16150 ug/kg
Deutsche Zahnaerztliche Zeitschrift. Vol. 34, Pg. 484, 1979.

oral-mouse LD50 184 mg/kg
Oyo Yakuri. Pharmacometrics. Vol. 2, Pg. 411, 1968.

oral-rat LD50 360 mg/kg
BEHAVIORAL: FOOD INTAKE (ANIMAL)
National Technical Information Service. Vol. OTS0555162

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
cosmetic agents
Recommendation for tin(ii) fluoride usage levels up to:
 not for fragrance use.
 
Recommendation for tin(ii) fluoride flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
Daily Med:search
NIOSH International Chemical Safety Cards:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):7783-47-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24550
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
difluorotin
Chemidplus:0007783473
EPA/NOAA CAMEO:hazardous materials
RTECS:7783-47-3
 
References:
 difluorotin
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:7783-47-3
Pubchem (cid):24550
Pubchem (sid):134990925
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
KEGG (GenomeNet):D05919
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2826.19.0000
MedlinePlusSupp:View
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•grade: nf (national formulary) •stannous fluoride is available as a usp grade containing a min of 71.2% stannous tin and 22.3-25.5% fluoride on an anhydrous basis, and a max of 0.5% weight loss on drying, 0.2% insoluble substances and 50 mgkg antimony. •stannous fluoride for oral topical use comes in the following 0.4% (0.1% fluoride ion) gels: easygel (with glycerin), du-more; gel-kam (with glycerin), scherer; gel-tin (with glycerin), young dental; omnii-gel (with glycerin), dunhall; stop home treatment 0.4% (with glycerin). a 30% (7.2% fluoride ion) solution is available as oral-b rinsing solution, concentrate. •-4 mesh, 99.9% purity grades. •available in an over the counter preparation, aim toothpaste, yielding 0.40% fluoride ion. available in the prescription preparations, iradicav stannous fluoride gel and iradicav rinse, each yielding 0.09% fluoride ion. •available topical application products take the form of tablets, capsules .
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 oral care agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 cap-tin mouthrinse
 crest
 difluoro-lamda2-stannane
 difluorotin
 easygel
 fluoristan
 gel-kam
 gel-tin
 iradicar SnF2
 iradicav SnF2
 king's gel-tin
 omnii-gel
 stancare
 stannane, difluoro-
 stop home treatment
 tin bifluoride
 tin difluoride
 tin fluoride
 tin(II) fluoride
 

Articles:

PubMed:Erosion protection comparison of stabilised SnF2 , mixed fluoride active and SMFP/arginine-containing dentifrices.
PubMed:Introduction. Stabilized stannous fluoride and dental erosion.
PubMed:The anticaries effect of a food extract (shiitake) in a short-term clinical study.
PubMed:Enamel protection: a comparison of marketed dentifrice performance against dental erosion.
PubMed:Effect of a stannous fluoride dentifrice on plaque formation and removal: a digital plaque imaging study.
PubMed:Influence of dentifrices and dietary components in saliva on wettability of pellicle-coated enamel in vitro and in vivo.
PubMed:Studies on stannous fluoride toothpaste and gel (1). Antimicrobial properties and staining potential in vitro.
PubMed:Clinical efficacy of an optimized stannous fluoride dentifrice, Part 5: A 3-month study of extrinsic tooth staining, northeast USA.
PubMed:Extrinsic tooth discoloration by metals and chlorhexidine. I. Surface protein denaturation or dietary precipitation?
PubMed:[Effects of pre-test food uptake and the use of stannous fluoride dentifrice on the biopsy method for the acid-resistance of surface enamel (author's transl)].
PubMed:Demineralizing effects of cooked food-saliva mixtures on fluoride-treated and nontreated enamel.
PubMed:Chairside procedures for using fluorides for preventing dental caries.
PubMed:Effect of stannous fluoride in food and in drinking water on caries prevention in rats on high sucrose and coarse corn diets.
 
Notes:
None found
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