EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

tetramethylammonium chloride
methanaminium, N,N,N-trimethyl-, chloride (1:1)

Supplier Sponsors

CAS Number: 75-57-0Picture of molecule3D/inchi
Other(deleted CASRN):251459-49-1
ECHA EINECS - REACH Pre-Reg:200-880-8
Beilstein Number:3911201
Molecular Weight:109.59864000
Formula:C4 H12 Cl N
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:viscosity controlling agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Pubchem Patents:Search
Physical Properties:
Appearance:white crystalline solid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 420.00 °C. @ 760.00 mm Hg
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: viscosity controlling agents
BOC Sciences
For experimental / research use only.
Tetramethylammonium chloride 98 % (TLC).
Odor: characteristic
Use: Non-selective K+ channel blocker. ADCs Cytotoxin
Charkit Chemical
Charkit Chemical
EMD Millipore
For experimental / research use only.
Tetramethylammonium Chloride
Glentham Life Sciences
Tetramethylammonium chloride
Santa Cruz Biotechnology
For experimental / research use only.
Tetramethylammonium Chloride ≥99%
Sigma-Aldrich: Sigma
For experimental / research use only.
Tetramethylammonium Chloride BioUltra, for molecular biology, ≥99.0% (AT)
For experimental / research use only.
Tetramethylammonium Chloride >98.0%(T)
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
unreported-guinea pig LDLo 20 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 7, Pg. 183, 1900.

intraperitoneal-mouse LD50 10 mg/kg
National Technical Information Service. Vol. OTS0536975

oral-mouse LDLo 125 mg/kg
Journal of Pharmaceutical Sciences. Vol. 69, Pg. 327, 1980.

unreported-mouse LDLo 20 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 7, Pg. 183, 1900.

intraperitoneal-rat LD50 10 mg/kg
National Technical Information Service. Vol. OTS0536975

oral-rat LD50 50 mg/kg
National Technical Information Service. Vol. OTS0536975

Dermal Toxicity:
subcutaneous-frog LDLo 2000 mg/kg
Skandinavisches Archiv fuer Physiologie. Vol. 10, Pg. 201, 1900.

subcutaneous-mouse LD50 40 mg/kg
National Technical Information Service. Vol. ORNL-5576

subcutaneous-rabbit LDLo 6 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 7, Pg. 183, 1900.

Inhalation Toxicity:
Not determined
Safety in Use Information:
viscosity controlling agents
Recommendation for tetramethylammonium chloride usage levels up to:
 not for fragrance use.
Recommendation for tetramethylammonium chloride flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
NIOSH International Chemical Safety Cards:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):75-57-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :6379
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:75-57-0
Pubchem (cid):6379
Pubchem (sid):134970909
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C11335
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2923.90.0000
Potential Blenders and core components note
None Found
Potential Uses:
 viscosity controlling agents
Occurrence (nature, food, other):note
 not found in nature
 ammonium, tetramethyl-, chloride
 methanaminium, N,N,N-trimethyl-, chloride
 methanaminium, N,N,N-trimethyl-, chloride (1:1)
 tetramethyl ammonium chloride
 tetramine chloride
N,N,N-trimethylmethanaminium chloride


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None found
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