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tetraethyl orthosilicate
orthosilicic acid, tetraethyl ester

Supplier Sponsors

Name:tetraethyl silicate
CAS Number: 78-10-4Picture of molecule3D/inchi
Other(deleted CASRN):827300-06-1
ECHA EINECS - REACH Pre-Reg:201-083-8
FDA UNII: 42064KRE49
Nikkaji Web:J5.506I
Beilstein Number:1422225
MDL:MFCD00009062
Molecular Weight:208.32950000
Formula:C8 H20 O4 Si
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:food contact resinous and polymeric coatings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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DG SANTE Food Contact Materials:tetraethyl orthosilicate
 
Physical Properties:
Appearance:colorless to pale yellow clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.93300 to 0.93700 @ 20.00 °C.
Pounds per Gallon - (est).: 7.773 to 7.806
Refractive Index:1.38100 to 1.38500 @ 20.00 °C.
Boiling Point: 168.80 °C. @ 760.00 mm Hg
Vapor Pressure:1.880000 mmHg @ 25.00 °C.
Flash Point: 116.00 °F. TCC ( 46.67 °C. )
Soluble in:
 water, 3.691e+004 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Achiewell
For experimental / research use only.
Tetraethoxysilane
ECSA Chemicals
TETRAETHYL ORTHOSILICATE
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
EMD Millipore
For experimental / research use only.
Tetraethyl Orthosilicate
Glentham Life Sciences
Tetraethoxysilane
Sigma-Aldrich: Aldrich
For experimental / research use only.
Tetraethyl orthosilicate 99.999% trace metals basis
Strem Chemicals
For experimental / research use only.
Tetraethoxysilane, min. 98% TEOS
TCI AMERICA
For experimental / research use only.
Tetraethyl Orthosilicate >96.0%(GC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LDLo 830 mg/kg
BLOOD: CHANGES IN SPLEEN KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
Nippon Eiseigaku Zasshi. Japanese Journal of Hygiene. Vol. 46, Pg. 231, 1991.

intravenous-rabbit LDLo 400 mg/kg
KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS LUNGS, THORAX, OR RESPIRATION: PLEURAL EFFUSION BLOOD: OTHER HEMOLYSIS WITH OR WITHOUT ANEMIA
Industrial Medicine. Vol. 6, Pg. 660, 1937.

oral-rat LD50 6270 mg/kg
Journal of Industrial Hygiene and Toxicology. Vol. 31, Pg. 60, 1949.

Dermal Toxicity:
skin-rabbit LD50 6300 uL/kg
Union Carbide Data Sheet. Vol. 7/23/1970

Inhalation Toxicity:
inhalation-guinea pig LCLo 700 ppm/6H
LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS BEHAVIORAL: GENERAL ANESTHETIC
Journal of Industrial Hygiene and Toxicology. Vol. 22, Pg. 288, 1940.

inhalation-mammal (species unspecified) LCLo 4500 mg/m3
LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA LIVER: FATTY LIVER DEGERATION BLOOD: OTHER CHANGES
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 3, Pg. 81, 1961.

inhalation-mouse LCLo 1000 mg/m3/2H
LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI BEHAVIORAL: GENERAL ANESTHETIC KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 5, Pg. 192, 1963.

inhalation-rat LCLo 1000 ppm/4H
Journal of Industrial Hygiene and Toxicology. Vol. 31, Pg. 343, 1949.

 
Safety in Use Information:
Category:
food contact resinous and polymeric coatings
Recommendation for tetraethyl orthosilicate usage levels up to:
 not for fragrance use.
 
Recommendation for tetraethyl orthosilicate flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the safety assessment of the substances tetraethyl orthosilicate, CAS No. 78-10-4, and hexamethyldisilazane, CAS No. 999 97 3, for use in food contact materials
View page or View pdf

EPI System: View
NIOSH International Chemical Safety Cards:search
NIOSH Pocket Guide:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):78-10-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :6517
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
tetraethyl silicate
Chemidplus:0000078104
EPA/NOAA CAMEO:hazardous materials
RTECS:78-10-4
 
References:
 tetraethyl silicate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:78-10-4
Pubchem (cid):6517
Pubchem (sid):134972962
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2931.90.9010
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 orthosilicic acid tetraethyl ester
 orthosilicic acid, tetraethyl ester
 silicon tetraethoxide
 tetraethyl ortho-silicate
 tetraethyl silicate
 
 
Notes:
None found
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