EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

tert-butyl hydroperoxide
hydroperoxide, 1,1-dimethylethyl-

Supplier Sponsors

CAS Number: 75-91-2Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:200-915-7
FDA UNII: 955VYL842B
Nikkaji Web:J2.397C
Beilstein Number:1098280
MDL:MFCD00002130
XlogP3-AA:0.60 (est)
Molecular Weight:90.12210000
Formula:C4 H10 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:indirect food additives: adhesives and components of coatings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
FDA Mainterm (IAUFC):75-91-2 ; TERT-BUTYL HYDROPEROXIDE
FDA Regulation:
FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.
 
Physical Properties:
Appearance:colorless clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.90100 @ 25.00 °C.
Melting Point: -8.00 °C. @ 760.00 mm Hg
Boiling Point: 120.00 to 121.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:5.470000 mmHg @ 25.00 °C.
Vapor Density:2.07 ( Air = 1 )
Flash Point: 95.00 °F. TCC ( 35.00 °C. )
logP (o/w): 1.230 (est)
Soluble in:
 water, 1.965e+004 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Charkit Chemical
BUTYL HYDROPEROXIDE, TERT- 70%
EMD Millipore
For experimental / research use only.
tert-Butyl Hydroperoxide
sds
Santa Cruz Biotechnology
For experimental / research use only.
tert-Butyl Hydroperoxide
Sigma-Aldrich: Aldrich
For experimental / research use only.
Luperox® TBH70X, tert-Butyl hydroperoxide solution 70 wt. % in H2O
sds
TCI AMERICA
For experimental / research use only.
tert-Butyl Hydroperoxide (70% in Water)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 370 mg/kg
BLOOD: HEMORRHAGE GASTROINTESTINAL: ALTERATION IN GASTRIC SECRETION BEHAVIORAL: IRRITABILITY
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 15, Pg. 90, 1979.

intraperitoneal-rat LD50 87 mg/kg
BEHAVIORAL: ATAXIA BEHAVIORAL: MUSCLE WEAKNESS
American Industrial Hygiene Association Journal. Vol. 19, Pg. 205, 1958.

oral-mouse LD50 320 mg/kg
BLOOD: HEMORRHAGE GASTROINTESTINAL: ALTERATION IN GASTRIC SECRETION BEHAVIORAL: IRRITABILITY
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 15, Pg. 90, 1979.

intraperitoneal-mouse LD50 246 mg/kg
"Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 30, 1982.

Dermal Toxicity:
skin-rat LD50 790 mg/kg
SPI Bulletin. Vol. 1/75-19B

skin-rabbit LD50 460 ul/kg
LIVER: OTHER CHANGES KIDNEY, URETER, AND BLADDER: OTHER CHANGES IN URINE COMPOSITION LUNGS, THORAX, OR RESPIRATION: CYANOSIS
ARCO Chemical Company Report. Vol. JUN1982

Inhalation Toxicity:
inhalation-mouse LC50 350 ppm/4H
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
American Industrial Hygiene Association Journal. Vol. 19, Pg. 205, 1958.

inhalation-rat LC50 500 ppm/4H
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
American Industrial Hygiene Association Journal. Vol. 19, Pg. 205, 1958.
 
Safety in Use Information:
Category:
indirect food additives: adhesives and components of coatings
Recommendation for tert-butyl hydroperoxide usage levels up to:
 not for fragrance use.
 
Recommendation for tert-butyl hydroperoxide flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NIOSH International Chemical Safety Cards:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):75-91-2
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :6410
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
2-hydroperoxy-2-methylpropane
Chemidplus:0000075912
EPA/NOAA CAMEO:hazardous materials
RTECS:75-91-2
 
References:
 2-hydroperoxy-2-methylpropane
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:75-91-2
Pubchem (cid):6410
Pubchem (sid):134971225
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2909.60.5000
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
•grades: 70%, 90% pure •the commercial product is a 70% solution in water
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
t-butyl hydroperoxide
tertiary-butyl hydroperoxide
tert-butylhydrogenperoxide
t-butylhydroperoxide
tert-butylhydroperoxide
tertiary-butylhydroperoxide
 cadox TBH
1,1-dimethyl ethyl hydroperoxide
 dimethylethyl hydroperoxide
1,1-dimethylethyl hydroperoxide
1,1-dimethylethylhydroperoxide
 hydroperoxide, 1,1-dimethylethyl
 hydroperoxide, 1,1-dimethylethyl-
 hydroperoxide, t-butyl
 hydroperoxide, tert-butyl
2-hydroperoxy-2-methylpropane
2-methyl-2-propanyl hydroperoxide
 perbutyl H
 trigonox A-75
 

Articles:

PubMed:Inhibitory effect of aqueous extracts from Miracle Fruit leaves on mutation and oxidative damage.
PubMed:Agent orange herbicides, organophosphate and triazinic pesticides analysis in olive oil and industrial oil mill waste effluents using new organic phase immunosensors.
PubMed:Antioxidant activity and protective effect of extract of Celosia cristata L. flower on tert-butyl hydroperoxide-induced oxidative hepatotoxicity.
PubMed:Chemical and cellular antioxidative properties of threadfin bream (Nemipterus spp.) surimi byproduct hydrolysates fractionated by ultrafiltration.
PubMed:Schisandra Chinensis Baillon regulates the gene expression of phase II antioxidant/detoxifying enzymes in hepatic damage induced rats.
PubMed:Black rice extract protected HepG2 cells from oxidative stress-induced cell death via ERK1/2 and Akt activation.
PubMed:Essential role of PH domain and leucine-rich repeat protein phosphatase 2 in Nrf2 suppression via modulation of Akt/GSK3β/Fyn kinase axis during oxidative hepatocellular toxicity.
PubMed:Assessment of the antioxidant and antiproliferative effects of sesquiterpenic compounds in in vitro Caco-2 cell models.
PubMed:Antioxidant effects of whey protein on muscle C2C12 cells.
PubMed:Hepatoprotective effects of fermented field water-dropwort (Oenanthe javanica) extract and its major constituents.
PubMed:Microbial phenolic metabolites improve glucose-stimulated insulin secretion and protect pancreatic beta cells against tert-butyl hydroperoxide-induced toxicity via ERKs and PKC pathways.
PubMed:Carotenoids inhibit lipid peroxidation and hemoglobin oxidation, but not the depletion of glutathione induced by ROS in human erythrocytes.
PubMed:IscR is a global regulator essential for pathogenesis of Vibrio vulnificus and induced by host cells.
PubMed:Inhibition of oxidative stress and lipid peroxidation by anthocyanins from defatted Canarium odontophyllum pericarp and peel using in vitro bioassays.
PubMed:Antioxidant activity and protective effects of peptide lunasin against oxidative stress in intestinal Caco-2 cells.
PubMed:Luteolin and luteolin-7-O-glucoside strengthen antioxidative potential through the modulation of Nrf2/MAPK mediated HO-1 signaling cascade in RAW 264.7 cells.
PubMed:An aqueous pomegranate seed extract ameliorates oxidative stress of human hepatoma HepG2 cells.
PubMed:Cytotoxic effects of procyanidins from Castanea mollissima Bl. shell on human hepatoma G2 cells in vitro.
PubMed:Antioxidant activity and protective effects of Trapa japonica pericarp extracts against tert-butylhydroperoxide-induced oxidative damage in Chang cells.
PubMed:The protective effect of eicosapentaenoic acid-enriched phospholipids from sea cucumber Cucumaria frondosa on oxidative stress in PC12 cells and SAMP8 mice.
PubMed:Influence of cysteine and methionine availability on protein peroxide scavenging activity and phenolic stability in emulsions.
PubMed:Gymnaster koraiensis and its major components, 3,5-di-O-caffeoylquinic acid and gymnasterkoreayne B, reduce oxidative damage induced by tert-butyl hydroperoxide or acetaminophen in HepG2 cells.
PubMed:DHA sensitizes FaO cells to tert-BHP-induced oxidative effects. Protective role of EGCG.
PubMed:Cocoa flavonoid epicatechin protects pancreatic beta cell viability and function against oxidative stress.
PubMed:Antioxidant activity of phenolics in leaves of three red pepper (Capsicum annuum) cultivars.
PubMed:Antigenotoxic effect of Tartary (Fagopyrum tataricum) and common (Fagopyrum esculentum) buckwheat flour.
PubMed:Protective effects of alkaloid compounds from Nelumbinis Plumula on tert-butyl hydroperoxide-induced oxidative stress.
PubMed:Protection of H9c2 rat cardiomyoblasts against oxidative insults by total paeony glucosides from Radix Paeoniae Rubrae.
PubMed:Protective effects of cerebrosides from sea cucumber and starfish on the oxidative damage in PC12 cells.
PubMed:Cocoa phenolic extract protects pancreatic beta cells against oxidative stress.
PubMed:Protective effect of Pinus koraiensis needle water extract against oxidative stress in HepG2 cells and obese mice.
PubMed:Anti-inflammatory activity of edible brown alga Eisenia bicyclis and its constituents fucosterol and phlorotannins in LPS-stimulated RAW264.7 macrophages.
PubMed:Wine extracts from Sardinian grape varieties attenuate membrane oxidative damage in Caco-2 cell monolayers.
PubMed:Chalcones from the flowers of Coreopsis lanceolata and their in vitro antioxidative activity.
PubMed:Protective effect of Paeonia anomala extracts and constituents against tert-butylhydroperoxide-induced oxidative stress in HepG2 cells.
PubMed:The hepatoprotection of caffeic acid and rosmarinic acid, major compounds of Perilla frutescens, against t-BHP-induced oxidative liver damage.
PubMed:Separation of the antioxidant compound quercitrin from Lindera obtusiloba Blume and its antimelanogenic effect on B16F10 melanoma cells.
PubMed:Protective effect of ganodermanondiol isolated from the Lingzhi mushroom against tert-butyl hydroperoxide-induced hepatotoxicity through Nrf2-mediated antioxidant enzymes.
PubMed:Synthesis and bioactivity profile of 5-s-lipoylhydroxytyrosol-based multidefense antioxidants with a sizeable (poly)sulfide chain.
PubMed:Protective effect of 70% ethanolic extract of Lindera obtusiloba Blume on tert-butyl hydroperoxide-induced oxidative hepatotoxicity in rats.
PubMed:Protective effects of oligomeric and polymeric procyanidin fractions from defatted grape seeds on tert-butyl hydroperoxide-induced oxidative damage in HepG2 cells.
PubMed:Modulatory effect of methanolic extract of Vernonia amygdalina (MEVA) on tert-butyl hydroperoxide-induced erythrocyte haemolysis.
PubMed:Assessment of the ability of seaweed extracts to protect against hydrogen peroxide and tert-butyl hydroperoxide induced cellular damage in Caco-2 cells.
PubMed:Phenolic extracts of brewers' spent grain (BSG) as functional ingredients - assessment of their DNA protective effect against oxidant-induced DNA single strand breaks in U937 cells.
PubMed:Cellular assessment of the extract of bambangan (Mangifera pajang) as a potential cytoprotective agent for the human hepatocellular HepG2 cell line.
PubMed:C-Phycocyanin protects SH-SY5Y cells from oxidative injury, rat retina from transient ischemia and rat brain mitochondria from Ca2+/phosphate-induced impairment.
PubMed:Differential oxidative stress induction and lethality of rat embryos after maternal exposure to t-butyl hydroperoxide during postimplantation period.
PubMed:In vitro protective effects of Thymus quinquecostatus Celak extracts on t-BHP-induced cell damage through antioxidant activity.
PubMed:Roles for SKN7 response regulator in stress resistance, conidiation and virulence in the citrus pathogen Alternaria alternata.
PubMed:Exposure of Pseudomonas aeruginosa to green tea polyphenols enhances the tolerance to various environmental stresses.
PubMed:Nitroderivatives of olive oil phenols protect HepG2 cells against oxidative stress.
PubMed:Anti-inflammatory activity of Korean thistle Cirsium maackii and its major flavonoid, luteolin 5-O-glucoside.
PubMed:Synthesis, characterization and in-vitro antitubercular activity of isoniazid-gelatin conjugate.
PubMed:Evaluation of hepatotoxicity and oxidative stress in rats treated with tert-butyl hydroperoxide.
PubMed:Optimisation of hydrolysis of purple sea urchin (Strongylocentrotus nudus) gonad by response surface methodology and evaluation of in vitro antioxidant activity of the hydrolysate.
PubMed:Anti-tumorigenic activity of sophoflavescenol against Lewis lung carcinoma in vitro and in vivo.
PubMed:Youngia denticulata protects against oxidative damage induced by tert-butylhydroperoxide in HepG2 cells.
PubMed:Isolation of phlorotannins from Eisenia bicyclis and their hepatoprotective effect against oxidative stress induced by tert-butyl hyperoxide.
PubMed:Comparative antioxidant capacities of quercetin and butylated hydroxyanisole in cholesterol-modified erythrocytes damaged by tert-butylhydroperoxide.
PubMed:Phlorhizin protects against erythrocyte cell membrane scrambling.
PubMed:Copper ability to induce premature senescence in human fibroblasts.
PubMed:Protective effects of three smoke flavouring phenols on oxidative damage and nitric oxide production.
PubMed:Protective mechanisms of anthocyanins from purple sweet potato against tert-butyl hydroperoxide-induced hepatotoxicity.
PubMed:Antimutagenic constituents of adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) with potential cancer chemopreventive activity.
PubMed:Alkyl hydroxytyrosyl ethers show protective effects against oxidative stress in HepG2 cells.
PubMed:Antioxidant effects of the chestnut (Castanea crenata) inner shell extract in t-BHP-treated HepG2 cells, and CCl4- and high-fat diet-treated mice.
PubMed:A tocotrienol-rich fraction from grape seeds inhibits oxidative stress induced by tert-butyl hydroperoxide in HepG2 cells.
PubMed:Antioxidant and hepatoprotective activities of five eggplant varieties.
PubMed:Protective effect of simple phenols from extravirgin olive oil against lipid peroxidation in intestinal Caco-2 cells.
PubMed:Protective effects of hesperidin against oxidative stress of tert-butyl hydroperoxide in human hepatocytes.
PubMed:Analysis of phosphorothionate pesticides using a chloroperoxidase pretreatment and acetylcholinesterase biosensor detection.
PubMed:Antioxidant effectiveness of coffee extracts and selected constituents in cell-free systems and human colon cell lines.
PubMed:5-Hydroxytrytophan inhibits tert-butylhydroperoxide (t-BHP)-induced oxidative damage via the suppression of reactive species (RS) and nuclear factor-kappaB (NF-kappaB) activation on human fibroblast.
PubMed:Hydroxytyrosol induces antioxidant/detoxificant enzymes and Nrf2 translocation via extracellular regulated kinases and phosphatidylinositol-3-kinase/protein kinase B pathways in HepG2 cells.
PubMed:Synergistic chondroprotective effect of alpha-tocopherol, ascorbic acid, and selenium as well as glucosamine and chondroitin on oxidant induced cell death and inhibition of matrix metalloproteinase-3--studies in cultured chondrocytes.
PubMed:Antioxidant properties of raisins (Vitis vinifera L.).
PubMed:Cellular DNA breakage by soy isoflavone genistein and its methylated structural analogue biochanin A.
PubMed:Synergic effects of alpha-tocopherol and beta-carotene on tert-butylhydroperoxide-induced HepG2 cell injury.
PubMed:Inhibition of suicidal erythrocyte death by xanthohumol.
PubMed:Antihepatotoxic effect of corn peptides against Bacillus Calmette-Guerin/lipopolysaccharide-induced liver injury in mice.
PubMed:Protectivity of blue honeysuckle extract against oxidative human endothelial cells and rat hepatocyte damage.
PubMed:Impact of gamma-irradiation on the antioxidative properties of sage, thyme, and oregano.
PubMed:The anti-inflammatory effect of kaempferol in aged kidney tissues: the involvement of nuclear factor-kappaB via nuclear factor-inducing kinase/IkappaB kinase and mitogen-activated protein kinase pathways.
PubMed:Protective role of myricetin on markers of oxidative stress in human erythrocytes subjected to oxidative stress.
PubMed:Cytoprotective and antioxidant activity of seabuckthorn (Hippophae rhamnoides L.) flavones against tert-butyl hydroperoxide-induced cytotoxicity in lymphocytes.
PubMed:Crude cacao Theobroma cacao extract reduces mutagenicity induced by benzo[a]pyrene through inhibition of CYP1A activity in vitro.
PubMed:[Oxidative stress modulation using polyphenol-rich blueberries: application on a human retinal cell model].
PubMed:Glycyrrhizic acid modulates t-BHP induced apoptosis in primary rat hepatocytes.
PubMed:Purification and antioxidant properties of bigeye tuna (Thunnus obesus) dark muscle peptide on free radical-mediated oxidative systems.
PubMed:Protective effect of linalool, myrcene and eucalyptol against t-butyl hydroperoxide induced genotoxicity in bacteria and cultured human cells.
PubMed:Protective mechanisms of Aralia continentalis extract against tert-butyl hydroperoxide-induced hepatotoxicity: in vivo and in vitro studies.
PubMed:Inhibition of lactoperoxidase-catalyzed 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) and tyrosine oxidation by tyrosine-containing random amino acid copolymers.
PubMed:Protection of human HepG2 cells against oxidative stress by cocoa phenolic extract.
PubMed:Pre- and co-treatment with xanthophyll enhances the anti-leukemic activity of adriamycin.
PubMed:Protective effect of caffeic acid phenethyl ester on tert-butyl hydroperoxide-induced oxidative hepatotoxicity and DNA damage.
PubMed:Re-evaluation of the antioxidant prenylated flavonoids from the roots of Sophora flavescens.
PubMed:Protective effect of vanilloids against tert-butyl hydroperoxide-induced oxidative stress in vero cells culture.
PubMed:Cancer chemoprotective effects of Curcuma xanthorrhiza.
PubMed:Cytotoxic and antioxidant activity of 4-methylthio-3-butenyl isothiocyanate from Raphanus sativus L. (Kaiware Daikon) sprouts.
PubMed:Mycotoxins in edible tree nuts.
PubMed:Evaluation of the probe dihydrocalcein acetoxymethylester as an indicator of reactive oxygen species formation and comparison with oxidative DNA base modification determined by modified alkaline elution technique.
PubMed:Inhibition of gap junctional intercellular communication and activation of mitogen-activated protein kinase by tumor-promoting organic peroxides and protection by resveratrol.
PubMed:Protective effect of aqueous extract of Perilla frutescens on tert-butyl hydroperoxide-induced oxidative hepatotoxicity in rats.
PubMed:Effect of coffee melanoidin on human hepatoma HepG2 cells. Protection against oxidative stress induced by tert-butylhydroperoxide.
PubMed:The potential antimutagenic and antioxidant effects of Maillard reaction products used as "natural antibrowning" agents.
PubMed:Free radical-mediated pre-hemolytic injury in human red blood cells subjected to lead acetate as evaluated by chemiluminescence.
PubMed:Phenolic-rich juice prevents DNA single-strand breakage and cytotoxicity caused by tert-butylhydroperoxide in U937 cells: the role of iron chelation.
PubMed:Isolation of chebulic acid from Terminalia chebula Retz. and its antioxidant effect in isolated rat hepatocytes.
PubMed:Modulatory effects of resveratrol, citroflavan-3-ol, and plant-derived extracts on oxidative stress in U937 cells.
PubMed:Involvement of ryanodine-operated channels in tert-butylhydroperoxide-evoked Ca2+ mobilisation in pancreatic acinar cells.
PubMed:Development of analytical procedures to study changes in the composition of meat phospholipids caused by induced oxidation.
PubMed:Flavonoids protect U-937 macrophages against tert-butylhydroperoxide induced oxidative injury.
PubMed:Involvement of p38 MAPK and Nrf2 in phenolic acid-induced P-form phenol sulfotransferase expression in human hepatoma HepG2 cells.
PubMed:Protective effects of synthetic hydroxytyrosol acetyl derivatives against oxidative stress in human cells.
PubMed:Investigation into the resistance of lactoperoxidase tolerant Escherichia coli mutants to different forms of oxidative stress.
PubMed:Antioxidant effects of aqueous extract of Terminalia chebula in vivo and in vitro.
PubMed:Radical scavenging and anti-lipoperoxidative activities of Smallanthus sonchifolius leaf extracts.
PubMed:Evaluation of antioxidant activity of Brazilian plants.
PubMed:Mechanism underlying oxidative stress-mediated lipotoxicity: exposure of J774.2 macrophages to triacylglycerols facilitates mitochondrial reactive oxygen species production and cellular necrosis.
PubMed:Protective role of tea catechins against oxidation-induced damage of type 2 diabetic erythrocytes.
PubMed:The drinking of a Salvia officinalis infusion improves liver antioxidant status in mice and rats.
PubMed:Protective effect of Mesona procumbens against tert-butyl hydroperoxide-induced acute hepatic damage in rats.
PubMed:Commonly consumed and naturally occurring dietary substances affect biomarkers of oxidative stress and DNA damage in healthy rats.
PubMed:Anti-genotoxic effects of tea catechins against reactive oxygen species in human lymphoblastoid cells.
PubMed:Selenite activates caspase-independent necrotic cell death in Jurkat T cells and J774.2 macrophages by affecting mitochondrial oxidant generation.
PubMed:Anthocyanins protect against DNA damage induced by tert-butyl-hydroperoxide in rat smooth muscle and hepatoma cells.
PubMed:Polymeric procyanidins as radical-scavenging components in red-hulled rice.
PubMed:Oxidative stress response of rat testis to model prooxidants in vitro and its modulation.
PubMed:Membrane depolarization of isolated rat liver mitochondria attenuates permeability transition pore opening and oxidant production.
PubMed:Physiological concentrations of (-)-epigallocatechin-3-O-gallate (EGCg) prevent chromosomal damage induced by reactive oxygen species in WIL2-NS cells.
PubMed:Detection of oxidant-induced slight chromosomal damage in cells by subsequent exposure to X-rays.
PubMed:In vivo protective effect of protocatechuic acid on tert-butyl hydroperoxide-induced rat hepatotoxicity.
PubMed:[The antioxidant activity of wild jujubi, crataegus and grape in vitro].
PubMed:Chronic exposure of HepG2 cells to excess copper results in depletion of glutathione and induction of metallothionein.
PubMed:Sedanolide, a natural phthalide from celery seed oil: effect on hydrogen peroxide and tert-butyl hydroperoxide-induced toxicity in HepG2 and CaCo-2 human cell lines.
PubMed:Two OPEEs (organic phase enzyme electrodes) used to check the percentage water content in hydrophobic foods and drugs.
PubMed:Black tea polyphenols, theaflavins, prevent cellular DNA damage by inhibiting oxidative stress and suppressing cytochrome P450 1A1 in cell cultures.
PubMed:Imaging of hydroperoxide and hydrogen peroxide-scavenging substances by photon emission.
PubMed:Effects of organosulfur compounds from garlic oil on the antioxidation system in rat liver and red blood cells.
PubMed:Influence of prenylated and non-prenylated flavonoids on liver microsomal lipid peroxidation and oxidative injury in rat hepatocytes.
PubMed:Antagonism of free-radical-induced damage of adlay seed and its antiproliferative effect in human histolytic lymphoma U937 monocytic cells.
PubMed:Sesquiterpene lactones with potential use as natural herbicide models. 2. guaianolides.
PubMed:Inhibition of tert-butyl hydroperoxide-induced cell membrane bleb formation by alpha-tocopherol and glutathione.
PubMed:Mechanism of protection by the flavonoids, quercetin and rutin, against tert-butylhydroperoxide- and menadione-induced DNA single strand breaks in Caco-2 cells.
PubMed:Protective effect of Hibiscus anthocyanins against tert-butyl hydroperoxide-induced hepatic toxicity in rats.
PubMed:Inhibition of lipid peroxidation by Lactobacillus acidophilus and Bifidobacterium longum.
PubMed:Alkylperoxyl radical-scavenging activity of various flavonoids and other phenolic compounds: implications for the anti-tumor-promoter effect of vegetables.
PubMed:Reactive oxygen species and lipid peroxidation product-scavenging ability of yogurt organisms.
PubMed:Male-mediated dominant lethal mutations in mice following prooxidant treatment.
PubMed:Effects of oleic acid, docosahexaenoic acid and eicosapentaenoic acid on background and genotoxin-induced frequencies of SCEs in Indian muntjac fibroblasts.
PubMed:Effect of caffeic acid on tert-butyl hydroperoxide-induced oxidative stress in U937.
PubMed:Fluorometric detection of paralytic shellfish poisoning toxins.
PubMed:Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes--reversal with (R)-alpha-lipoic acid supplementation.
PubMed:Toxicity of linoleic acid hydroperoxide to Saccharomyces cerevisiae: involvement of a respiration-related process for maximal sensitivity and adaptive response.
PubMed:Protective effects of dried flower extracts of Hibiscus sabdariffa L. against oxidative stress in rat primary hepatocytes.
PubMed:Glutathione synthetase is dispensable for growth under both normal and oxidative stress conditions in the yeast Saccharomyces cerevisiae due to an accumulation of the dipeptide gamma-glutamylcysteine.
PubMed:Admixture of a multivitamin preparation to parenteral nutrition: the major contributor to in vitro generation of peroxides.
PubMed:Beta-carotene and lutein protect HepG2 human liver cells against oxidant-induced damage.
PubMed:Glutathione is an essential metabolite required for resistance to oxidative stress in the yeast Saccharomyces cerevisiae.
PubMed:Correlation of the OSR/ZRCI gene product and the intracellular glutathione levels in Saccharomyces cerevisiae.
PubMed:Singlet oxygen and peroxyl radicals regulate carotenoid biosynthesis in Phaffia rhodozyma.
PubMed:Selenium deficiency suppresses the S-glutathiolation of carbonic anhydrase III in rat hepatocytes under oxidative stress.
PubMed:Oxidation of heme proteins as a measure of oxidative damage to liver tissue slices.
PubMed:Protection by vitamin E, selenium, and beta-carotene against oxidative damage in rat liver slices and homogenate.
PubMed:Phenotypic character of the lipid hydroperoxide-resistant mutant: Positive relationship between flocculation and resistance against lipid hydroperoxide inSaccharomyces cerevisiae.
PubMed:The role of NADPH in the regulation of glucose-6-phosphate and 6-phosphogluconate dehydrogenases in rat adipose tissue.
PubMed:Comparison of the cytotoxicity of different hydroperoxides to V79 cells.
PubMed:Lipid peroxidation in rat tissue slices: effect of dietary vitamin E, corn oil-lard and menhaden oil.
PubMed:Lability of red blood cell membranes to lipid peroxidation: application to humans fed polyunsaturated lipids.
PubMed:Rapid headspace gas chromatography of hexanal as a measure of lipid peroxidation in biological samples.
PubMed:Damage to protein synthesis concurrent with lipid peroxidation in rat liver slices: effect of halogenated compounds, peroxides, and vitamin E1.
PubMed:Deterioration of membrane morphology, phospholipids, and cytoskeletal protein in rat erythrocytes exposed to tert-butyl hydroperoxide: protection by exogenous glutathione fails in selenium deficiency.
PubMed:tert-butyl hydroperoxide-induced hemolysis of alpha-tocopherol-decreased erythrocytes from selenium-deficient and selenium-adequate rats.
PubMed:Zinc suppression of free radicals induced in cultures of rat hepatocytes by iron, t-butyl hydroperoxide, and 3-methylindole.
PubMed:Damage to DNA concurrent with lipid peroxidation in rat liver slices.
PubMed:Lipid peroxidation measured as thiobarbituric acid-reactive substances in tissue slices: characterization and comparison with homogenates and microsomes.
PubMed:Peroxides, genes and cancer.
PubMed:The pentose phosphate cycle is regulated by NADPH/NADP ratio in rat liver.
PubMed:Formation of long-lived hydroxyl free radical adducts of proline and hydroxyproline in a Fenton reaction.
 
Notes:
a direct-acting oxidative stress-inducing agent used to examine the effects of oxidant stress on ca(2+)-dependent signal transduction in vascular endothelial cells. it is also used as a catalyst in polymerization reactions and to introduce peroxy groups into organic molecules.
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2021 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy