Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Assay: | 95.00 to 100.00
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Food Chemicals Codex Listed: | No |
Soluble in: |
| water, 5066 mg/L @ 25 °C (est) |
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
intravenous-dog LD50 50 mg/kg Journal of Medicinal Chemistry. Vol. 19, Pg. 918, 1976.
intravenous-human TDLo 1044 mg/kg/5D KIDNEY, URETER, AND BLADDER: OTHER CHANGES
LIVER: LIVER FUNCTION TESTS IMPAIRED
GASTROINTESTINAL: NAUSEA OR VOMITING Cancer Vol. 34, Pg. 993, 1974.
intraperitoneal-mouse LD50 360 mg/kg Journal of Medicinal Chemistry. Vol. 19, Pg. 918, 1976.
intravenous-mouse LD50 275 mg/kg Journal of Medicinal Chemistry. Vol. 19, Pg. 918, 1976.
parenteral-mouse LD50 264 mg/kg Cancer Chemotherapy Reports. Vol. 48, Pg. 1, 1965.
intravenous-rat LD50 138 mg/kg Cancer Chemotherapy Reports. Vol. 29, Pg. 91, 1963.
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Dermal Toxicity: |
subcutaneous-mouse LD50 335 mg/kg National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | natural substances and extractives |
Recommendation for streptozocin usage levels up to: | | not for fragrance use.
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Recommendation for streptozocin flavor usage levels up to: |
| not for flavor use.
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Safety References:
References:
| 1-methyl-1-nitroso-3-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea |
NIST Chemistry WebBook: | Search Inchi |
Canada Domestic Sub. List: | 18883-66-4 |
Pubchem (cid): | 29327 |
Pubchem (cas): | 18883-66-4 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
2- | deoxy-2-(3-methyl-3-nitrosoureido)-alpha(and beta)-D-glucopyranose | D- | glucopyranose, 2-deoxy-2-(((methylnitrosoamino)carbonyl)amino)- | 1- | methyl-1-nitroso-3-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea | | zanosar |
Articles:
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