sodium tetraborate
2,4,6,8,9-pentaoxa-1,3,5,7-tetraborabicyclo[3.3.1]nonane-3,7-diolate, sodium salt (1:2)
 
Notes:
Listed in the EAFUS Food Additive Database (Jan. 2001) but with no reported use
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disodium;3,7-dioxido-2,4,6,8,9-pentaoxa-1,3,5,7-tetraborabicyclo[3.3.1]nonane (Click)
CAS Number: 1330-43-4Picture of molecule
Other: 1039387-27-3
ECHA EINECS - REACH Pre-Reg: 215-540-4
FDA UNII: 8191EN8ZMD
MDL: MFCD00081185
Molecular Weight: 201.21793856
Formula: B4 Na2 O7
NMR Predictor: Predict (works with chrome or firefox)
Category: buffering agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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 FDA/DG SANTE Petitions, Reviews, Notices:
EU SANCO Sodium tetraborate (borax) View-review
DG SANTE Food Additives: sodium tetraborate
DG SANTE Food Contact Materials: sodium tetraborate
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Physical Properties:
Appearance: white crystalline powder (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 2.36700 @  25.00 °C.
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: buffering agents
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Suppliers:
American Elements
Sodium Tetraborate, Anhydrous 99%
Odor: characteristic
Use: Sodium Tetraborate, Anhydrous is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
EMD Millipore
For experimental / research use only.
di-Sodium tetraborate
Santa Cruz Biotechnology
For experimental / research use only.
Borax Anhydrous ≥99%
Sigma-Aldrich: Aldrich
For experimental / research use only.
Sodium Tetraborate 99%
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: buffering agents
Recommendation for sodium tetraborate usage levels up to:
 not for fragrance use.
 
Recommendation for sodium tetraborate flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Scientific Opinion on the re-evaluation of boric acid (E 284) and sodium tetraborate (borax) (E 285) as food additives
View page or View pdf
ECHA (ESR): View
ClinicalTrials.gov: search
NIOSH International Chemical Safety Cards: search
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NLM Hazardous Substances Data Bank: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 1330-43-4
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 10219853
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 disodium;3,7-dioxido-2,4,6,8,9-pentaoxa-1,3,5,7-tetraborabicyclo[3.3.1]nonane
Chemidplus: 0001330434
EPA/NOAA CAMEO: hazardous materials
RTECS: 1330-43-4
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References:
 disodium;3,7-dioxido-2,4,6,8,9-pentaoxa-1,3,5,7-tetraborabicyclo[3.3.1]nonane
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 1330-43-4
Pubchem (cid): 10219853
Pubchem (sid): 135263547
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
FooDB: FDB015387
Export Tariff Code: 2840.11.0000
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ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 buffering agents 
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 disodium bicyclo[3.3.1]tetraboroxane-3,7-diolate
 disodium tetraborate
 disodium tetraborate anhydrous
 disodium;3,7-dioxido-2,4,6,8,9-pentaoxa-1,3,5,7-tetraborabicyclo[3.3.1]nonane
2,4,6,8,9-pentaoxa-1,3,5,7-tetraborabicyclo[3.3.1]nonane-3,7-diolate, sodium salt (1:2)
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Articles:
PubMed: Development and Validation of a Micellar Capillary Electrophoresis Method for Determination of IFN╬▓-1b in Lyophilized Formulation of a Biosimilar Product.
PubMed: Determination of alditols by capillary electrophoresis with indirect laser-induced fluorescence detection.
PubMed: Polyamidoamine dendrimers as off-column binding agent and in-column pseudostationary phase for efficient and sensitive capillary electrophoretic analysis of fluoroquinolones in chicken muscles.
PubMed: Estimation of tea catechin levels using micellar electrokinetic chromatography: a quantitative approach.
PubMed: Separation of steroids using vegetable oils in microemulsion electrokinetic capillary chromatography.
PubMed: Merging a sensitive capillary electrophoresis-ultraviolet detection method with chemometric exploratory data analysis for the determination of phenolic acids and subsequent characterization of avocado fruit.
PubMed: Microchip electrophoresis with amperometric detection for a novel determination of phenolic compounds in olive oil.
PubMed: A rapid sample screening method for authenticity control of whiskey using capillary electrophoresis with online preconcentration.
PubMed: Differentiation of organic goat's milk based on its hippuric acid content as determined by capillary electrophoresis.
PubMed: Multivariant optimization, validation, and application of capillary electrophoresis for simultaneous determination of polyphenols and phenolic acids in Brazilian wines.
PubMed: Separation and determination of nitrofuran antibiotics in turbot fish by microemulsion electrokinetic chromatography.
PubMed: Analysis of potential adulteration in herbal medicines and dietary supplements for the weight control by capillary electrophoresis.
PubMed: Development and validation of a microemulsion electrokinetic chromatography method for patulin quantification in commercial apple juice.
PubMed: Phenolic composition in grape (Vitis vinifera L. cv. Malbec) ripened with different solar UV-B radiation levels by capillary zone electrophoresis.
PubMed: Pesticide analysis in rose wines by micellar electrokinetic chromatography.
PubMed: Multiple pesticide analysis in wine by MEKC combined with solid-phase microextraction and sample stacking.
PubMed: Enantioseparation of chiral tropa alkaloids by means of cyclodextrin-modified microemulsion electrokinetic chromatography.
PubMed: MEKC combined with SPE and sample stacking for multiple analysis of pesticides in water samples at the ng/L level.
PubMed: Capillary electrophoretic analysis of gamma-aminobutyric acid and alanine in tea with in-capillary derivatization and fluorescence detection.
PubMed: On the effect of tetraborate ions in the generation of colored products in thermally processed glycine-carbohydrate solutions.
PubMed: Determination of phenolic compounds in grape skin by capillary electrophoresis with simultaneous dual fluorescence and diode array absorption detection after dynamic superheated liquid leaching.
PubMed: Impurity profiling of atropine sulfate by microemulsion electrokinetic chromatography.
PubMed: Chiral MEKC-LIF of amino acids in foods: analysis of vinegars.
PubMed: The influence of oxidation on proteolysis in raw milk.
PubMed: High-performance capillary electrophoresis with indirect UV detection for determination of alpha-galactosides in Leguminosae and Brassicaceae.
PubMed: A new micellar electrokinetic capillary chromatography method for separation of the components of the aminoglycoside antibiotics.
PubMed: Effects of boron foliar applications on vegetative and reproductive growth of sunflower.
PubMed: [Studies on the determination of serum thymic factor by capillary zone electrophoresis].
PubMed: Simultaneous determination of ingredients in a vitamin-enriched drink by micellar electrokinetic chromatography.
PubMed: Sodium tetraborate effects on mortality and reproduction of Anastrepha suspensa (Diptera: Tephritidae).
PubMed: A method for determining fumonisin B1 in corn using immunoaffinity column clean-up and thin layer chromatography/densitometry.
PubMed: The analysis of aminoglycoside antibiotics by capillary electrophoresis.
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