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Category:special dietary and nutritional additives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white crystalline (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 710.00 °C. @ 760.00 mm Hg
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| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est)
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| | moisture Sensitive. |
| Soluble in: |
| | water, 1e+006 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 7 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Toxicology and Applied Pharmacology. Vol. 20, Pg. 89, 1971.
intravenous-rat LD50 3 mg/kg
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
oral-rabbit LD50 2.25 mg/kg
Hygiene and Sanitation Vol. 35(1-3), Pg. 176, 1970.
oral-mouse LD50 7.08 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(2), Pg. 14, 1970.
intravenous-mouse LD50 5 mg/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
CARDIAC: OTHER CHANGES
PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)
Neurotoxicology. Vol. 2, Pg. 383, 1981.
oral-guinea pig LD50 5.06 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(2), Pg. 14, 1970.
oral-cattle LDLo 9900 ug/kg
Journal of the American College of Toxicology. Vol. 5(1), Pg. 45, 1986.
parenteral-chicken LD50 8500 ug/kg
Neuropharmacology. Vol. 25, Pg. 493, 1990.
intravenous-dog LD50 1916 ug/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
CARDIAC: ARRHYTHMIAS (INCLUDING CHANGES IN CONDUCTION)
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Proceedings of the South Dakota Academy of Science. Vol. 36, Pg. 173, 1957.
oral-guinea pig LD50 5060 ug/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(2), Pg. 14, 1970.
oral-man TDLo 24 mg/kg
GASTROINTESTINAL: NAUSEA OR VOMITING
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Veterinary and Human Toxicology. Vol. 39, Pg. 304, 1997.
oral-mouse LD50 7080 ug/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 35(2), Pg. 14, 1970.
intramuscular-rabbit LD50 2530 ug/kg
Archiv fuer Experimentelle Veterinaermedizin. Vol. 30, Pg. 627, 1976.
oral-rabbit LD50 2250 ug/kg
Hygiene and Sanitation Vol. 35(1-3), Pg. 176, 1970.
intraperitoneal-rabbit LDLo 4 mg/kg
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
intravenous-rabbit LDLo 1971 ug/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 33, Pg. 270, 1928.
parenteral-rabbit LDLo 1971 ug/kg
Clinical Toxicology. Vol. 17, Pg. 171, 1980.
parenteral-rat LD50 6570 ug/kg
Clinical Toxicology. Vol. 17, Pg. 171, 1980.
intraperitoneal-rat LDLo 5476 ug/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY)
LUNGS, THORAX, OR RESPIRATION: CYANOSIS
Journal of Pharmacology and Experimental Therapeutics. Vol. 58, Pg. 454, 1936.
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| Dermal Toxicity: |
subcutaneous-mouse LD50 13 mg/kg
Sangyo Igaku. Japanese Journal of Industrial Health. Vol. 17, Pg. 491, 1975.
subcutaneous-dog LDLo 4 mg/kg
Environmental Quality and Safety, Supplement. Vol. 1, Pg. 1, 1975.
subcutaneous-rabbit LDLo 6 mg/kg
ENDOCRINE: HYPOGLYCEMIA
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Proceedings of the Society for Experimental Biology and Medicine. Vol. 24, Pg. 251, 1926.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | special dietary and nutritional additives |
| Recommendation for sodium selenite usage levels up to: | | | not for fragrance use.
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| Recommendation for sodium selenite flavor usage levels up to: |
| | not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
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Scientific Opinion on the safety and efficacy of selenium compounds (E8) as feed additives for all animal species: sodium selenite (coated granulated preparation), based on a dossier submitted by Doxal Italia S.p.A
View page or View pdf
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Safety and efficacy of selenium compounds (E8) as feed additives for all animal species: sodium selenite, based on a dossier submitted by Retorte GmbH Selenium Chemicals and Metals
View page or View pdf
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Safety and efficacy of selenium compounds (E8) as feed additives for all animal species: sodium selenite, based on a dossier submitted by Todini and Co SpA
View page or View pdf
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| EPI System: View |
| ClinicalTrials.gov:search |
| Daily Med:search |
| NIOSH International Chemical Safety Cards:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA GENetic TOXicology:Search |
| EPA Substance Registry Services (TSCA):10102-18-8 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :24934 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:2 |
| disodium selenite |
| Chemidplus:0010102188 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:10102-18-8 |
References:
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | D10530 |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2842.90.0000 |
| FDA Listing of Food Additive Status: | View |
| ChemSpider: | View |
| Wikipedia: | View |
Formulations/Preparations:
•bo-se liquid (sc, im injections) (schering-plough animal health corp): sodium selenite, 2.19 mgml (1 mg seml); vitamin e, 50 mg (68 u.s.p. units)ml
•l-se liquid (sc, im injections) (schering-plough animal health corp): sodium selenite, 2.19 mgml (1 mg seml); vitamin e, 50 mg (68 u.s.p. units)ml
•seletoc minicaps and caps capsules (oral) (schering-plough animal health corp): sodium selenite, 2.19 mg (1 mg se); vitamin e, 56.2 mg (68 i.u.) or sodium selenite, 0.548 mg (0.25 mg se); vitamin e, 14 mg (17.1 i.u.)
•mu-se liquid (im, sc injection) (schering-plough animal health corp): sodium selenite, 10.95 mg (5 mg se)ml; vitamin e, 50 mg (68 u.s.p units)ml
•e-se emulsion (iv, im injection) (schering-plough animal health corp): sodium selenite, 5.48 mg (2.5 mg se)ml; vitamin e, 50 mg (68 i.u.)ml; 250 mg polyoxyethylated vegetable oil, and water for injection.
•seletoc injection (im, sc injection) (schering-plough animal health corp): sodium selenite, 2.19 mg (1 mg se)ml; vitamin e, 50 mg (68 i.u.)ml; 100 mg of polyoxyethylated vegetable oil, 1:10,000 thimerosal, and water for injection.
•velenium emulsion (im, sc injection) (fort dodge animal health, division of wyeth): sodium selenite, 10.95 mg (5 mg se)ml; vitamin e, 50 mg (68 u.s.p. units)ml
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Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | disodium selenite | | | disodium selenium trioxide | | | natriumselenit | | | selenious acid (H2SeO3), disodium salt | | | selenious acid disodium salt | | | selenious acid, disodium salt | | | selenious acid, sodium salt (2:1) | | | sodium biselenite | | | sodium selenite [NA2630] [Poison] | | | sodium selenium oxide | | | sodiumselenite |
Articles:
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3D/inchi
