EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

sodium phosphate tribasic
phosphoric acid sodium salt (1:3)

Sponsors

CAS Number: 7601-54-9Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:231-509-8
FDA UNII:SX01TZO3QZ
Nikkaji Web:J3.742G
MDL:MFCD00003510
Molecular Weight:163.93986984
Formula:Na3 O4 P
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:buffering agents, emulsion stabilizers, sequestrants, acidity regulators
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
1975 Sodium phosphate tribasic View-review
EU SANCO Sodium phosphates View-review
JECFA Food Additive: Trisodium phosphate
GSFA Codex: Trisodium phosphate (339(iii))
FDA Mainterm: SODIUM PHOSPHATE, TRIBASIC
FDA Regulation:
FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.169 Pasteurized process cheese.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.173 Pasteurized process cheese food.


FDA PART 133 -- CHEESES AND RELATED CHEESE PRODUCTS
Subpart B--Requirements for Specific Standardized Cheese and Related Products
Sec. 133.179 Pasteurized process cheese spread.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.141 Artificially sweetened fruit jelly.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.161 Artificially sweetened fruit preserves and jams.


FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart D--Specific Usage Additives
Sec. 173.310 Boiler water additives.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart B--Substances Utilized To Control the Growth of Microorganisms
Sec. 178.1010 Sanitizing solutions.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart B--Multiple Purpose GRAS Food Substances
Sec. 182.1778 Sodium phosphate.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart G--Sequestrants1
Sec. 182.6778 Sodium phosphate.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart I--Nutrients
Sec. 182.8778 Sodium phosphate.


FDA PART 73 -- LISTING OF COLOR ADDITIVES EXEMPT FROM CERTIFICATION
Subpart A--Foods
Sec. 73.85 Caramel.
 
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 97.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Insoluble in:
 alcohol
 
Organoleptic Properties:
Odor Description:at 100.00 %. odorless
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: buffering agents
chelating agents
 
Suppliers:
American Elements
Sodium Phosphate Tribasic Anhydrous 99%
Odor: characteristic
Use: Sodium Phosphate Tribasic Anhydrous is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
TRISODIUM PHOSPHATE ANHYDROUS GRANULAR FCC
BOC Sciences
For experimental / research use only.
Trisodium phosphate tribasic, technical
Covalent Chemical
Trisodium Phosphate
ECSA Chemicals
Trisodium Phosphate
Company Profile
Foodchem International
Trisodium Phosphate
Graham Chemical
Trisodium Phosphate
Penta International
SODIUM PHOSPHATE TRIBASIC ANHYDROUS
Sigma-Aldrich: Aldrich
For experimental / research use only.
Sodium phosphate 96%
Silver Fern Chemical
Trisodium Phosphate
Odor: characteristic
Use: Trisodium Phosphate is commonly used in cleaning agents and detergents, water softeners, textiles, papers, photography, paint removers, food additives, dietary supplements, and as an emulsifier.
SINOTEC
Trisodium phosphate (TSP)
Odor: characteristic
Use: Used as soft water agent, cleaning agent for electroplating color fixer for fabric dyeing, flux for fabric dyeing , flux for enamel ware manufacturing
Zhong Ya Chemical
Sodium Phosphate, Tri
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-rabbit LDLo 1580 mg/kg
"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.

Dermal Toxicity:
skin-rabbit LD > 300 mg/kg
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 47, 1990.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: buffering agents, emulsion stabilizers, sequestrants, acidity regulators
Recommendation for sodium phosphate tribasic usage levels up to:
 not for fragrance use.
 
Recommendation for sodium phosphate tribasic flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Treatment of poultry carcasses with chlorine dioxide, acidified sodium chlorite, trisodium phosphate and peroxyacids
View page or View pdf

Assessment of one published review on health risks associated with phosphate additives in food
View page or View pdf

EPI System: View
NIOSH International Chemical Safety Cards:search
NLM Hazardous Substances Data Bank:Search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):7601-54-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24243
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
trisodium phosphate
Chemidplus:0007601549
EPA/NOAA CAMEO:hazardous materials
RTECS:7601-54-9
 
References:
 trisodium phosphate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:7601-54-9
Pubchem (cid):24243
Pubchem (sid):134987258
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):D09000
HMDB (The Human Metabolome Database):Search
FooDB:FDB013349
Export Tariff Code:2835.23.0000
Haz-Map:View
Household Products:Search
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
Formulations/Preparations:
•trisodium phosphate, 1-4% in crest fluoride gel and crest fluoride toothpaste. •anhydrous, technical grades: anhydrous and crystalline, granular and powder food grades. •grade: commercial, high purity, cp chemically pure - a grade designation signifying a minimum of impurities, but not 100% purity, fcc (anhydrous), anhydrous salt
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 buffering agents
 chelating agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 phosphoric acid sodium salt (1:3)
 phosphoric acid trisodium salt
 sodium phosphate tribasic
 sodium phosphate, tribasic
 sodium tertiary phosphate
 trisodium orthophosphate
 trisodium phosphate
 TSP
 

Articles:

PubMed:Impact of sertraline salt form on the oxidative stability in powder blends.
PubMed:Effect of repeated sodium phosphate loading on cycling time-trial performance and VO2peak.
PubMed:Capillary electrophoresis with laser-induced fluorescence detection for ATP quantification in spermatozoa and oocytes.
PubMed:Taurine determination by capillary electrophoresis with laser-induced fluorescence detection: from clinical field to quality food applications.
PubMed:Sodium phosphate loading improves laboratory cycling time-trial performance in trained cyclists.
PubMed:In vitro dissolution studies of sodium diclofenac granules coated with Eudragit L-30D-55 by fluidized-bed system.
PubMed:Improved method for the storage of groundwater samples containing volatile organic analytes
PubMed:Polymeric calcium phosphate cements: setting reaction modifiers.
PubMed:Effects of phosphate loading on metabolic and myocardial responses to maximal and endurance exercise.
PubMed:Effects of phosphate loading on oxygen uptake, ventilatory anaerobic threshold, and run performance.
PubMed:GLC determination of aprindine in human plasma using a nitrogen--phosphorus flame-ionization detector.
PubMed:High pressure liquid chromatographic determination of vitamin D3 in instant nonfat dried milk.
PubMed:On the relation of inflammation to the chemical constitution of injurious agents. On the pharmacology of inflammation.
PubMed:Dissolution rate of mixtures of weak acids and tribasic sodium phosphate.
 
Notes:
Nutrient supplement, pH control agent, sequestrant, stabiliser, protein modifier, emulsifier in production of processed cheeses, indirect food additive arising from use as a boiler water additive
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