sodium oxide
disodium monoxide
None found
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disodium;oxygen(2-) (Click)
CAS Number: 1313-59-3Picture of molecule
Other: 1242458-86-1
ECHA EINECS - REACH Pre-Reg: 215-208-9
FDA UNII: 3075U8R23D
MDL: MFCD00046201
Molecular Weight: 61.97873856
Formula: Na2 O
NMR Predictor: Predict (works with chrome or firefox)
Category: buffering agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 2.27000 @  25.00 °C.
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Organoleptic Properties:
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: buffering agents
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American Elements
Sodium Oxide
Santa Cruz Biotechnology
For experimental / research use only.
Sodium Oxide 80%
Sigma-Aldrich: Aldrich
For experimental / research use only.
Sodium Oxide 80%
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Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: buffering agents
Recommendation for sodium oxide usage levels up to:
 not for fragrance use.
Recommendation for sodium oxide flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
NIOSH International Chemical Safety Cards: search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 1313-59-3
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 73971
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
Chemidplus: 0001313593
RTECS: WC4800000 for cas# 1313-59-3
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NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 1313-59-3
Pubchem (cid): 73971
Pubchem (sid): 135032341
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2825.90.6000
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
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Potential Blenders and core components note
None Found
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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 disodium monoxide
 sodium oxide (Na2O)
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PubMed: Adhesion phenomena between particles according to the content of organic binder in core for thin-wall casting.
PubMed: Structure, biodegradation behavior and cytotoxicity of alkali-containing alkaline-earth phosphosilicate glasses.
PubMed: An effective utilization of the slag from acid leaching of coal-waste: preparation of water glass with a low-temperature co-melting reaction.
PubMed: Sol-gel derived bioactive glasses with low tendency to crystallize: synthesis, post-sintering bioactivity and possible application for the production of porous scaffolds.
PubMed: Enzyme-based biosilica and biocalcite: biomaterials for the future in regenerative medicine.
PubMed: Reduction-melting combined with a Na₂CO₃ flux recycling process for lead recovery from cathode ray tube funnel glass.
PubMed: Investigating the effect of SiO2-TiO 2-CaO-Na 2O-ZnO bioactive glass doped hydroxyapatite: characterisation and structural evaluation.
PubMed: Effects of blended-cement paste chemical composition changes on some strength gains of blended-mortars.
PubMed: Phosphate-based glass fiber vs. bulk glass: Change in fiber optical response to probe in vitro glass reactivity.
PubMed: Safety evaluation of a bioglass-polylactic acid composite scaffold seeded with progenitor cells in a rat skull critical-size bone defect.
PubMed: Influence of sodium content on the properties of bioactive glasses for use in air abrasion.
PubMed: Nanoscale chains control the solubility of phosphate glasses for biomedical applications.
PubMed: Effect of various additives on microstructure, mechanical properties, and in vitro bioactivity of sodium oxide-calcium oxide-silica-phosphorus pentoxide glass-ceramics.
PubMed: Effects of biosilicate(®) scaffolds and low-level laser therapy on the process of bone healing.
PubMed: DFT modeling of 45S5 and 77S soda-lime phospho-silicate glass surfaces: clues on different bioactivity mechanism.
PubMed: A correlation study between multiple sclerosis and type 1 diabetes incidences and geochemical data in Europe.
PubMed: Alkali oxide containing mesoporous bioactive glasses: synthesis, characterization and in vitro bioactivity.
PubMed: Biosilica aging: from enzyme-driven gelation via syneresis to chemical/biochemical hardening.
PubMed: Structural study of Al2O3-Na2O-CaO-P2O5 bioactive glasses as a function of aluminium content.
PubMed: Histopathological, cytotoxicity and genotoxicity evaluation of Biosilicate® glass-ceramic scaffolds.
PubMed: A comparative study on oxidative and antioxidative markers of serum and follicular fluid in GnRH agonist and antagonist cycles.
PubMed: Intense 2.7 µm emission and structural origin in Er3+-doped bismuthate (Bi2O3-GeO2-Ga2O3-Na2O) glass.
PubMed: Flower-like Na2O nanotip synthesis via femtosecond laser ablation of glass.
PubMed: Development and bioactivity evaluation of bioglasses with low Na2O content based on the system Na 2O-CaO-MgO-P 2O 5-SiO 2.
PubMed: Biocompatibility analysis of bioglass® 45S5 and biosilicate® implants in the rabbit eviscerated socket.
PubMed: A novel bioactive vitroceramic presents similar biological responses as autogenous bone grafts.
PubMed: Structural investigations on sodium-lead borophosphate glasses doped with vanadyl ions.
PubMed: Effects of CaO/P2O5 ratio on the structure and elastic properties of SiO2-CaO-Na2O-P2O5 bioglasses.
PubMed: Compositional and microstructural design of highly bioactive P2O5-Na2O-CaO-SiO2 glass-ceramics.
PubMed: Structural characterization and physical properties of P2O5-CaO-Na2O-TiO2 glasses by Fourier transform infrared, Raman and solid-state magic angle spinning nuclear magnetic resonance spectroscopies.
PubMed: Low-level laser therapy, at 60 J/cm2 associated with a Biosilicate(®) increase in bone deposition and indentation biomechanical properties of callus in osteopenic rats.
PubMed: Effect of Fe2O3 concentration on the structure of the SiO2-Na2O-Al2O3-B2O3 glass system.
PubMed: Mixed alkali effect and optical properties of Ni2+ doped 20ZnO+xLi2O+(30-x)Na2O+50B2O3 glasses.
PubMed: Assessment of antimicrobial effect of Biosilicate® against anaerobic, microaerophilic and facultative anaerobic microorganisms.
PubMed: Preparation and characterization of antibacterial P₂O5-CaO-Na₂O-Ag₂O glasses.
PubMed: Synthesis, bioactivity and preliminary biocompatibility studies of glasses in the system CaO-MgO-SiO2-Na2O-P2O5-CaF2.
PubMed: Exercise training enhances the skeletal muscle response to radiation-induced oxidative stress.
PubMed: Biosilicate® and low-level laser therapy improve bone repair in osteoporotic rats.
PubMed: A new sol-gel process for producing Na(2)O-containing bioactive glass ceramics.
PubMed: Titanium and strontium-doped phosphate glasses as vehicles for strontium ion delivery to cells.
PubMed: The biocompatibility of silver-containing Na2O.CaO.2SiO2 glass prepared by sol-gel method: in vitro studies.
PubMed: Extraction of alumina and sodium oxide from red mud by a mild hydro-chemical process.
PubMed: Effect of preparation conditions on the properties of bioactive glasses for testing SBF.
PubMed: Quantitative structure-property relationships of potentially bioactive fluoro phospho-silicate glasses.
PubMed: [Determination of major elements in soil from cancer village by X-ray fluorescence spectrometry].
PubMed: [Determination of major elements in superphosphate by X-ray fluorescence spectrometry].
PubMed: State-selective energy transfer from Er3+ to Eu3+ in Bi2O3-GeO2-Ga2O3-Na2O glasses.
PubMed: Structure and properties of strontium-doped phosphate-based glasses.
PubMed: Evaluation of CaO-SiO2-P2O5-Na2O-Fe2O3 bioglass-ceramics for hyperthermia application.
PubMed: Do bioactive glasses convey a disinfecting mechanism beyond a mere increase in pH?
PubMed: Evaluation of physical-chemical properties and biocompatibility of a microrough and smooth bioactive glass particles.
PubMed: Silicate release from glass for pharmaceutical preparations.
PubMed: Direct correlation between nonrandom ion hopping and network structure in ion-conducting borophosphate glasses.
PubMed: Ti K-edge XANES study of the local environment of titanium in bioresorbable TiO2-CaO-Na2O-P2O5 glasses.
PubMed: Adsorption removal of phosphate from aqueous solution by active red mud.
PubMed: A combination of soy isoflavone supplementation and exercise improves lipid profiles and protects antioxidant defense-systems against exercise-induced oxidative stress in ovariectomized rats.
PubMed: Removal of lead ions from solution by phosphosilicate glass.
PubMed: In vivo behavior of bioactive phosphate glass-ceramics from the system P2O5-Na2O-CaO containing TiO2.
PubMed: Crystallization kinetics of bioactive glasses in the ZnO-Na2O-CaO-SiO2 system.
PubMed: Quantum chemical and vibrational investigation of sodium exchanged gamma-alumina surfaces.
PubMed: In vitro study of dentinal tubule occlusion with sol-gel DP-bioglass for treatment of dentin hypersensitivity.
PubMed: Influence of hydropower dams on the composition of the suspended and riverbank sediments in the Danube.
PubMed: Compositional dependence on the in vitro bioactivity of invert or conventional bioglasses in the Si-Ca-Na-P system.
PubMed: Use of laterite for the removal of fluoride from contaminated drinking water.
PubMed: Enhancement of luminescence properties in Er3+ doped TeO2-Na2O-PbX (X=O and F) ternary glasses.
PubMed: Effect of water and alkali modifications on ETS-10 for the cycloaddition of CO2 to propylene oxide.
PubMed: Upconversion and fluorescence spectral studies of Er3+/Yb3+-codoped Bi2Q3-GeO2-Ga2Q3-Na2O glasses.
PubMed: Co(3)O(4) nanoparticles produced by mechanochemical reactions.
PubMed: Interfacial reactions of glasses for biomedical application by scanning transmission electron microscopy and microanalysis.
PubMed: Formation of hydroxyapatite onto glasses of the CaO-MgO-SiO2 system with B2O3, Na2O, CaF2 and P2O5 additives.
PubMed: Final report on the safety assessment of potassium silicate, sodium metasilicate, and sodium silicate.
PubMed: The crystallization of an aluminosilicate glass in the K2O-Al2O3-SiO2 system.
PubMed: Cation environments and spatial distribution in Na2O-B2O3 glasses: new results from solid state NMR.
PubMed: Cation diffusion and ionic conductivity in soda-lime silicate glasses.
PubMed: Effects of MgO-CaO-P2O5-Na2O-based additives on mechanical and biological properties of hydroxyapatite.
PubMed: Influence of sodium oxide content on bioactive glass properties.
PubMed: [Effect of nitric oxide donor (NaNO2) on the stability of non-transformed and malignant cells to ultraviolet and gamma-radiation].
PubMed: CaO--P2O5--Na2O-based sintering additives for hydroxyapatite (HAp) ceramics.
PubMed: Phosphate glasses for tissue engineering: Part 2. Processing and characterisation of a ternary-based P2O5-CaO-Na2O glass fibre system.
PubMed: Phosphate glasses for tissue engineering: Part 1. Processing and characterisation of a ternary-based P2O5-CaO-Na2O glass system.
PubMed: [Na and Mg K-edge XANES study in silicate glasses].
PubMed: Microstructural dependence on relevant physical-mechanical properties on SiO2-Na2O-CaO-P2O5 biological glasses.
PubMed: Effect of sodium content on the crystallization behavior of fluoramphibole glass-ceramics.
PubMed: Mechanical properties of glass-only porcelains prepared by the use of two feldspathic frits with different thermal properties.
PubMed: Investigation of the solubility and ion release in the glass system K2O-Na2O-CaO-P2O5.
PubMed: 'Fluxes' and chemical solubility in dental porcelains.
PubMed: Investigation of thermal parameters and crytallisation in a ternary CaO-Na2O-P2O5-based glass system.
PubMed: The effect of moisture on compressional and shear wave speeds in unconsolidated granular material
PubMed: Initial events at the bioactive glass surface in contact with protein-containing solutions.
PubMed: Characterization of bioactive glass-reinforced HAP-polymer composites.
PubMed: Gel-derived materials of a CaO-P(2)O(5)-SiO(2) system modified by boron, sodium, magnesium, aluminum, and fluorine compounds.
PubMed: Determination of the (Na+) Sternheimer antishielding factor by 23Na NMR spectroscopy on sodium oxide chloride, Na3OCl.
PubMed: Treatment of tooth fracture by medium energy CO2 laser and DP-bioactive glass paste: compositional, structural, and phase changes of DP-bioglass paste after irradiation by CO2 laser.
PubMed: Apatite formation on PDMS-modified CaO-SiO2-TiO2 hybrids prepared by sol-gel process.
PubMed: [Study on antimutagenic effect of lanthanum carbonate in CA test, UDS test and MN test].
PubMed: [External quality control of the laboratory determination of glucose in the urine and material for its realization].
PubMed: Properties and cytotoxicity of water soluble Na2O-CaO-P2O5 glasses.
PubMed: Influence of modification of Na2O in a glass matrix on the strength of leucite-containing porcelains.
PubMed: Glass transition temperatures of dental porcelains determined by DSC measurement.
PubMed: Compositional dependence of bioactivity of glasses in the system Na2O-K2O-MgO-CaO-B2O3-P2O5-SiO2.
PubMed: In vitro induction of abnormal anaphases by contaminating atmospheric dust from the City of Mexicali, Baja California, Mexico.
PubMed: Facile Preparation of 3,7-Diazabicyclo[3.3.0]octane and 3,7,10-Triheterocyclic [3.3.3]Propellane Ring Systems from 1,5-Diazacyclooctane 3,7-Derivatives(1).
PubMed: Detection of multiple boron sites in glasses by 11B satellite transition nuclear magnetic resonance spectroscopy.
PubMed: Measurements of spin-lattice relaxation times, T1, in Na2O-MgO-SiO2 glasses doped with MnO.
PubMed: [The effect of phenazine methosulfate on human erythrocytes].
PubMed: A method for investigating the metabolism of the transportable fraction of plutonium aerosols.
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