sodium fluorosilicate
silicate(2-), hexafluoro-, sodium (1:2)
None found
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disodium;hexafluorosilicon(2-) (Click)
CAS Number: 16893-85-9Picture of molecule
Other: 1202391-51-2
ECHA EINECS - REACH Pre-Reg: 240-934-8
FDA UNII: 806AV2E065
MDL: MFCD00003491
Molecular Weight: 188.05525776
Formula: F6 Na2 Si
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: antiplaque agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Appearance: white granular powder (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 2.68000 @  25.00 °C.
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
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Organoleptic Properties:
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antiplaque agents
oral care agents
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American Elements
Sodium Silicofluoride 99%
Odor: characteristic
Use: Sodium Silicofluoride is a water insoluble Silicon source for use in oxygen-sensitive applications, such as metal production. Fluoride compounds have diverse applications in current technologies and science, from oil refining and etching to synthetic organic chemistry and the manufacture of pharmaceuticals. Magnesium Fluoride, for example, was used by researchers at the Max Planck Institute for Quantum Optics in 2013 to create a novel mid-infrared optical frequency comb composed of crystalline microresonators, a development that may lead to future advances in molecular spectroscopy. Fluorides are also commonly used to alloy metals and for optical deposition. Certain fluoride compounds can be produced at nanoscale and in ultra high purity forms. Sodium Silicofluoride is generally immediately available in most volumes. Ultra high purity and high purity compositions improve both optical quality and usefulness as scientific standards. Nanoscale (See also Nanotechnology Information and Quantum Dots) elemental powders and suspensions, as alternative high surface area forms, may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
Graham Chemical
Sodium Silicofluoride
Santa Cruz Biotechnology
For experimental / research use only.
Sodium hexafluorosilicate ≥99%
Sigma-Aldrich: Aldrich
For experimental / research use only.
Sodium hexafluorosilicate
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Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD50  70 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 53(11), Pg. 80, 1988.

oral-rabbit LD50  125 mg/kg
Farm Chemicals Handbook. Vol. -, Pg. C268, 1991.

oral-rat LD50  125 mg/kg
Agricultural Research Service, USDA Information Memorandum. Vol. 20, Pg. 21, 1966.

Dermal Toxicity:
subcutaneous-frog LDLo 448 mg/kg
Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 124, Pg. 133, 1937.

subcutaneous-rat LDLo 70 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 39, Pg. 246, 1930.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: antiplaque agents
Recommendation for sodium fluorosilicate usage levels up to:
 not for fragrance use.
Recommendation for sodium fluorosilicate flavor usage levels up to:
 not for flavor use.
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Safety References:
NIOSH International Chemical Safety Cards: search
NLM Hazardous Substances Data Bank: Search
Toxicology Citations: Search
EPA GENetic TOXicology: Search
Env. Mutagen Info. Center: Search
EPA Substance Registry Services (TSCA): 16893-85-9
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 28127
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
Chemidplus: 0016893859
EPA/NOAA CAMEO: hazardous materials
RTECS: 16893-85-9
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NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 16893-85-9
Pubchem (cid): 28127
Pubchem (sid): 134993609
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
KEGG (GenomeNet): C19040
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2826.20.0000
Haz-Map: View
Household Products: Search
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
•granular bait •grades: technical; c.p. •the average grade of commerce is approx. 98% pure.
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Potential Blenders and core components note
None Found
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Potential Uses:
 oral care agents 
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Occurrence (nature, food, other): note
 not found in nature
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 disodium hexafluorosilicate
 disodium hexafluorosilicate (2-)
 disodium hexafluorosilicate (8CI)(9CI)
 disodium hexafluorosilicate(2-)
 disodium silicofluoride
 silicate(2-), hexafluoro-, disodium
 silicate(2-), hexafluoro-, sodium (1:2)
 sodium fluorosilicate [UN2674] [Poison]
 sodium hexafluorosilicate
 sodium hexafluosilicate
 sodium silicofluoride
 sodium silicon fluoride
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PubMed: Na2SiF6:Cu,P: a new OSL phosphor for the radiation dosimetric applications.
PubMed: Effect of sodium fluorosilicate on the properties of Portland cement.
PubMed: Fatal cases of acute suicidal sodium and accidental zinc fluorosilicate poisoning. Review of acute intoxications due to fluoride compounds.
PubMed: Ice analog halos.
PubMed: Induction of apoptosis by sodium fluorosilicate treatment in human osteogenic sarcoma (HOS) cells.
PubMed: Effect of a two-solution fluoride mouth rinse on deposition of loosely bound fluoride on sound root tissue and remineralization of root lesions in vitro.
PubMed: Deposition of fluoride on tooth surfaces by a two-solution mouthrinse in vitro.
PubMed: Diffusion of fluorides in human dental enamel in vitro.
PubMed: [Effect of rations containing fluorine ion on biochemical and hematological indices of body status].
PubMed: [''Alumbrin'' (sodium fluorosilicate) as a drug against swine ascaridosis].
PubMed: [Possibility of health impairment in workers conserving hides with sodium fluorosilicate].
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