EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

sodium ethoxide
ethanol, sodium salt (1:1)

Supplier Sponsors

Name:sodium;ethanolate
CAS Number: 141-52-6Picture of molecule3D/inchi
Other(deleted CASRN):24448-24-6
ECHA EINECS - REACH Pre-Reg:205-487-5
FDA UNII: 1I9504387J
Nikkaji Web:J91.259J
Beilstein Number:3593646
MDL:MFCD00012417
Molecular Weight:68.05081928
Formula:C2 H5 Na O
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Sigma-Aldrich
For experimental / research use only.
Sodium Ethoxide technical, ≥95% (T)
TCI AMERICA
For experimental / research use only.
Sodium Ethoxide (ca. 20% in Ethanol)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for sodium ethoxide usage levels up to:
 not for fragrance use.
 
Recommendation for sodium ethoxide flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NIOSH International Chemical Safety Cards:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):141-52-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :2723922
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
sodium;ethanolate
Chemidplus:0000141526
 
References:
 sodium;ethanolate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:141-52-6
Pubchem (cid):2723922
Pubchem (sid):134975417
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2905.19.9090
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 caustic alcohol
 ethanol, sodium salt
 ethanol, sodium salt (1:1)
 ethoxysodium
 ethyl alcohol, sodium salt
 sodium ethanolate
 sodium ethylate
 sodium;ethanolate
 

Articles:

US Patents:7,927,643 - Compositions of oxo-terpene derivatives and process for preparing the same
PubMed:Heat-induced Antigen Retrieval in Conventionally Processed Epon-embedded Specimens: Procedures and Mechanisms.
PubMed:Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1,5-a][1,3,5]triazines as thymidine phosphorylase inhibitors.
PubMed:Synthesis and antimicrobial evaluation of some novel bis-α,β-unsaturated ketones, nicotinonitrile, 1,2-dihydropyridine-3-carbonitrile, fused thieno[2,3-b]pyridine and pyrazolo[3,4-b]pyridine derivatives.
PubMed:A solvent free, four-component synthesis and 1,3-dipolar cycloaddition of 4(H)-pyrans with nitrile oxides: synthesis and discovery of antimycobacterial activity of enantiomerically pure 1,2,4-oxadiazoles.
PubMed:Catalytic enantioselective N-nitroso aldol reaction of γ,δ-unsaturated δ-lactones.
PubMed:The evaluation of various kinetic models for base-catalyzed ethanolysis of palm oil.
PubMed:A green expedient synthesis of pyridopyrimidine-2-thiones and their antitubercular activity.
PubMed:Synthesis and biological activity of 2-(bis((1,3,4-oxadiazolyl/1,3,4-thiadiazolyl)methylthio)methylene)malononitriles.
PubMed:Rapid synthesis of flavor compound 4-ethyloctanoic acid under microwave irradiation.
PubMed:Synthesis of 3-(quinolin-2-yl)- and 3,6-bis(quinolin-2-yl)-9H-carbazoles.
PubMed:Synthesis and pharmacological evaluation of novel substituted and unsubstituted N-(benzoylphenyl)-1H-indole-2-carboxamides as potent antihypertriglyceridemic agents.
PubMed:9,10-Dioxa-1,2-diaza-anthracene derivatives from tetrafluoropyridazine.
PubMed:Chemical synthesis and characterization of palm oil-based difatty acyl thiourea.
PubMed:Ethanolysis of N-substituted norbornane epoxyimides: discovery of diverse pathways depending on substituent's character.
PubMed:Synthesis, X-ray crystal structure study and antitumoral evaluations of 5,6-disubstituted pyrimidine derivatives.
PubMed:Difatty acyl urea from corn oil: synthesis and characterization.
PubMed:Catalytic asymmetric three-component Mannich-type reaction of alkenyl trichloroacetates.
PubMed:Bifunctional heterogeneous catalysis of silica-alumina-supported tertiary amines with controlled acid-base interactions for efficient 1,4-addition reactions.
PubMed:Synthesis and characterization of N,N'-carbonyl difatty amides from palm oil.
PubMed:Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities.
PubMed:Self-assembly and characterization of a novel 2D network polymer containing a 60-membered organotin macrocycle.
PubMed:Tuning of chemo- and regioselectivities in multicomponent condensations of 5-aminopyrazoles, dimedone, and aldehydes.
PubMed:Synthesis of an isomeric mixture (24RS,25RS) of sodium scymnol sulfate.
PubMed:Unusual condensation of 3-Thia[5](1,1')ferrocenophane-1,5-dione with glyoxal. Formation of [1.1](2,3)thiopheno(1,1')ferrocenophane-1,7-dione.
PubMed:Surface roughness analysis of fiber post conditioning processes.
PubMed:Nitric oxide reacts with methoxide.
PubMed:A general stereoselective method for the synthesis of cyclopropanecarboxylates. A new version of the homologous Horner-Wadsworth-Emmons reaction.
PubMed:Regioselective synthesis and antitumor screening of some novel N-phenylpyrazole derivatives.
PubMed:An atom efficient, solvent-free, green synthesis and antimycobacterial evaluation of 2-amino-6-methyl-4-aryl-8-[(E)-arylmethylidene]-5,6,7,8-tetrahydro-4H-pyrano[3,2-c]pyridine-3-carbonitriles.
PubMed:First example of 5/6-O-linked pseudosaccharides: synthesis of bicyclic nucleosides containing azido or extended carbohydrate moiety.
PubMed:Novel regioselective formation of S- and N-hydroxyl-alkyls of 5-(3-chlorobenzo[b]thien-2-yl)-3-mercapto-4H-1,2,4-triazole and a facile synthesis of triazolo-thiazoles and thiazolo-triazoles. Role of catalyst and microwave.
PubMed:Novel regioselective hydroxyl-alkylation of 4,5-diphenylimidazole-2-thione and a competitive intramolecular ring closure of the S-hydroxyalkyl-imidazoles to imidazo[2,1-b]thiazines and thiazoles. Role of catalyst, microwave irradiation, and solid support.
PubMed:The intensity of immunogold labeling of deplasticized acrylic sections compared to deplasticized epoxy sections-Theoretical deductions and experimental data.
PubMed:Optimization of biodiesel production from castor oil.
PubMed:Synthesis and characterization of alkoxide-derived pt nanoparticles.
PubMed:Synthesis of 3-hydroxy-6-oxo[1,2,4]triazin-1-yl alaninamides, a new class of cyclic dipeptidyl ureas.
PubMed:Improving the quality of the quartz fiber postcore bond using sodium ethoxide etching and combined silane/adhesive coupling.
PubMed:Use of anti-fluorophore antibody to achieve high-sensitivity immunolocalizations of transporters and ion channels.
PubMed:Improved access to 2-O-monobenzyl ethers of beta-cyclodextrin as precursors of catalysts for organophosphoryl esters hydrolysis.
PubMed:Novel immobilization of titanium dioxide (TiO2) on the fluidizing carrier and its application to the degradation of azo-dye.
PubMed:Post-surface conditioning improves interfacial adhesion in post/core restorations.
PubMed:Aminoparathion: a highly reactive metabolite of parathion. 1. Reactions with polyphenols and polyphenol oxidase.
PubMed:Self-assembly of dialkyltin moieties and mercaptobenzoic acid into macrocyclic complexes with hydrophobic "pseudo-cage" or double-cavity structures: supramolecular infrastructures involving intermolecular C-H...S weak hydrogen bonds and pi-pi interactions.
PubMed:Extractive spectrofluorometric determination of quinalphos using fluorescein in environmental samples.
PubMed:Immunohistochemical staining of epoxy resin sections of peripheral nerve.
PubMed:Susceptibility of a polycaprolactone-based root canal filling material to degradation. I. Alkaline hydrolysis.
PubMed:Synthesis of new triazolopyrimidines and substituted pyrimidines.
PubMed:Investigations of a novel process to the framework of benzo[c]cinnoline.
PubMed:Antibacterial and bioactive silver-containing Na2O x CaO x 2SiO2 glass prepared by sol-gel method.
PubMed:Self-assembly of diorganotin(IV) moieties and 2-pyrazinecarboxylic acid: syntheses, characterizations and crystal structures of monomeric, polymeric or trinuclear macrocyclic compounds.
PubMed:Synthesis and in vitro antimicrobial activities of 2-hydroxy-6-methyl-7-(arylamino)-1,7-dihydropurin-8-ones.
PubMed:Fluorometric variable-temperature kinetics investigations of the transesterification reaction of procaine with aliphatic alcohols.
PubMed:Regioselective enzyme-catalyzed synthesis of sophorolipid esters, amides, and multifunctional monomers.
PubMed:Alkylation of the inverted porphyrin nickel(II) complex by dihalogenalkanes: formation of monomeric and dimeric derivatives.
PubMed:Electronic effects and the stereochemistries in rearrangement-displacement reactions of triaryl(halomethyl)silanes with fluoride and with alkoxide ions.
PubMed:Immunofluorescence technique for 100-nm-thick semithin sections of Epon-embedded tissues.
PubMed:Multiplicity control in the polygeminal diazeniumdiolation of active hydrogen bearing carbons: chemistry of a new type of trianionic molecular propeller.
PubMed:Synthesis of 1,2-unsaturated pyranosylphosphonate nucleosides from 3,4,6-tri-O-acetyl-D-glycal.
PubMed:Re-evaluation of epoxy resin sections for light and electron microscopic immunostaining.
PubMed:Synthesis, reactions and antimicrobial activity of new cyclopenta[e]thieno[2,3-b]pyridines and related heterocyclic systems.
PubMed:Deplasticizing or etching of epoxy sections with different concentrations of sodium ethoxide to enhance the immunogold labeling.
PubMed:Bioactivation mechanisms of haloalkene cysteine S-conjugates modeled by gas-phase, ion-molecule reactions.
PubMed:Comparison of the immunolabeling of heated and deplasticized epoxy sections on the electron microscopical level.
PubMed:Diaminobenzidine as a myelin stain in semithin plastic sections.
PubMed:Antigen detection on resin sections and methods for improving the immunogold labeling by manipulating the resin.
PubMed:Effective GC-MS procedure for detecting iso-LSD in urine after base-catalyzed conversion to LSD.
PubMed:Pre-osteoblastic proliferation assessed with BrdU in undecalcified, Epon-embedded adult rat trabecular bone.
PubMed:Synthesis and antiproliferative and antiviral activity of carbohydrate-modified pyrrolo[2,3-d]pyridazin-7-one nucleosides.
PubMed:How to examine the antigen-damaging effect of sodium ethoxide on deplasticized epoxy sections.
PubMed:Preparation and characterization of alkylated poly(vinyl alcohol) hydrogels using alkyl halides.
PubMed:Furanfurin and thiophenfurin: two novel tiazofurin analogues. Synthesis, structure, antitumor activity, and interactions with inosine monophosphate dehydrogenase.
PubMed:Antigen unmasking for immunoelectron microscopy: labeling is improved by treating with sodium ethoxide or sodium metaperiodate, then heating on retrieval medium.
PubMed:Mechanism for antigen detection on deplasticized epoxy sections.
PubMed:Protein-ubiquinone interaction: synthesis and biological properties of ethoxy ubiquinone derivatives.
PubMed:Immunocytochemical localization of delta 3, delta 2-enoyl-CoA isomerase and NADPH-dependent-2,4-dienoyl-CoA reductase in rat kidney.
PubMed:Synthesis of some new 3-(2'-heterocyclicethyl)-2-methyl-3,4- dihydroquinazolin-4-one derivatives as antimicrobial agents.
PubMed:Comparison of lectin reactivity in the vessel beds of the rat eye.
PubMed:Photometric determination of malathion with molybdenum.
PubMed:Bromodeoxyuridine (BrdUrd) immunohistochemistry in undecalcified plastic-embedded tissue. Elimination of the DNA denaturation step.
PubMed:[Structure correction and synthesis of subspinosin].
PubMed:Ultrastructural immunogold labeling of glial filaments in osmicated and unosmicated epoxy-embedded tissue.
PubMed:Application of the avidin-biotin-peroxidase complex (ABC-peroxidase) technique to the identification of human papillomavirus antigens on semithin sections by electron microscopy.
PubMed:Xanthine oxidase inhibition: effect of an N-alkyl substituent on C-2 of the nucleus of 8-azahypoxanthine.
PubMed:On-grid immunogold labeling of glial intermediate filaments in epoxy-embedded tissue.
PubMed:[Detection of fibronectin and collagen types I, III, IV and V in semithin sections of the human aorta].
PubMed:Immunocytochemical localization of peroxisomal enzymes in human liver biopsies.
PubMed:Partial characterization of lectin binding sites of retinal photoreceptor outer segments and interphotoreceptor matrix.
PubMed:Immunocytochemical localization of the myelin-associated glycoprotein. Fact or artifact?
PubMed:Light microscopic immunocytochemical demonstration of peroxisomal enzymes in epon sections.
PubMed:Immunohistochemical localization of the delta antigen associated with hepatitis B virus in liver biopsy sections embedded in Araldite.
PubMed:Immunohistochemistry of types I and II collagen in undecalcified skeletal tissues.
PubMed:Differentiation of A-, B- and D-cells of guinea-pig pancreas using semi-thin epoxy-resin sections.
PubMed:Retrospective demonstration of endogenous peroxidase activity in plastic-embedded tissues conventionally prepared for electron microscopy.
PubMed:Post-embedding immunoperoxidase staining of glial fibrillary acidic protein for light and electron microscopy.
PubMed:Analytical scanning electron microscopy and x-ray microdiffractometry of renal calculi using etched plastic sections.
PubMed:New cyclopenta[a]naphthalene derivatives. Synthesis of 2-(carbamylmethyl)-8-hydroxy-3H-cyclopental[a]naphthalene as a possible deoxyribonucleic acid binding agent.
PubMed:Total synthesis of stereospecific sphingosine and ceramide.
PubMed:Immuno-electron-cytochemical localization of the somatostatin cells in the human antral mucosa.
PubMed:Synthesis of certain 4-oxo-1.2.3.4-tetrahydroquinoline and benzazocine derivatives likely to possess analgesic activity.
PubMed:[Determination of hexachlorocyclohexane by direct titration with sodium ethoxide in anhydrous medium].
PubMed:[Research on nitrogen heterocyclic compounds. IX. Synthesis of 5-hydroxy-2,4-dicarbethoxypyrroles].
PubMed:Reaction mechanism in aromatic heterocyclic compounds. X. Kinetics of the reaction of carcinogenic 4-nitroquinoline 1-oxide and its derivatives with sodium ethoxide.
PubMed:Nucleosides. X. The action of sodium ethoxide on 3'-0-tosyl-2'-deoxyadenosine.
PubMed:[A METHOD FOR ISOLATING SODIUM ETHOXIDE FROM ALCOHOL AND SOLID SODIUM HYDROXIDE].
PubMed:[Studies on the syntheses of 4, 5-disubstituted isoxazoles and their cleavage reaction with sodium ethoxide. V. On the reactions of isoxazole and alpha-cyanoketone possessing furan ring].
PubMed:On the preparation of optically active phenyl-p-tolyl-methanesulphonic acid and its racemisation by sodium ethoxide.
 
Notes:
a clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. it has bactericidal activity and is used often as a topical disinfectant. it is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages.
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