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polydimethylsiloxanes

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Name:dimethyl-bis(trimethylsilyloxy)silane
CAS Number: 63148-62-9Picture of molecule3D/inchi
Other(deleted CASRN):12648-49-6
FDA UNII: 9G1ZW13R0G
Nikkaji Web:J99.786B
Molecular Weight:236.53358000
Formula:C8 H24 O2 Si3
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:indirect food additives: adhesives and components of coatings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
FCN 643 Siloxanes and silicones, di-Me View - notice
DG SANTE Food Contact Materials:polydimethylsiloxane (Mw > 6 800 Da)
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.96300 @ 25.00 °C.
Refractive Index:1.40400 @ 20.00 °C.
Flash Point: 600.00 °F. TCC ( 315.56 °C. )
Soluble in:
 water, 0.002918 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
ECSA Chemicals
DIMETHICONE 10 CST
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
ECSA Chemicals
DIMETHICONE 350
Glentham Life Sciences
Silicone oil, 350 cSt
Glentham Life Sciences
Silicone oil, 500 cSt
Mosselman
Silicone Oil 350
OQEMA
LanCos SI20-350
OQEMA
LanCos SI20-50
Shiva Chemicals and Pharmaceuticals
Silicone oil
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-guinea pig LD > 10000 mg/kg
National Technical Information Service. Vol. OTS0590148

intraperitoneal-mouse LDLo 16 mL/kg
IMMUNOLOGICAL INCLUDING ALLERGIC: DECREASE IN HUMORAL IMMUNE RESPONSE GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" IMMUNOLOGICAL INCLUDING ALLERGIC: DECREASE IN CELLULAR IMMUNE RESPONSE
National Technical Information Service. Vol. OTS0572697

intramuscular-rat LD > 1200 uL/kg
IMMUNOLOGICAL INCLUDING ALLERGIC: INCREASE IN HUMORAL IMMUNE RESPONSE
National Technical Information Service. Vol. OTS0572813

oral-rat LD > 50 mL/kg
Union Carbide Data Sheet. Vol. 1/14/1972

oral-rat LD > 5000 mg/kg
National Technical Information Service. Vol. OTS0572658

oral-rat LD50 > 17000 mg/kg
KIDNEY, URETER, AND BLADDER: OTHER CHANGES
National Technical Information Service. Vol. OTS0537687

oral-rat LD50 > 24000 mg/kg
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
National Technical Information Service. Vol. LMF-69

Dermal Toxicity:
skin-rabbit LD > 20 mL/kg
Union Carbide Data Sheet. Vol. 1/14/1972

skin-rabbit LD > 10200 mg/kg
National Technical Information Service. Vol. OTS0572436

skin-rabbit LD50 > 2000 mg/kg
BEHAVIORAL: FOOD INTAKE (ANIMAL) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"
National Technical Information Service. Vol. OTS0537687

Inhalation Toxicity:
inhalation-rabbit LC > 978000 mg/m3/7.5
National Technical Information Service. Vol. OTS0590149

 
Safety in Use Information:
Category:
indirect food additives: adhesives and components of coatings
Recommendation for polydimethylsiloxanes usage levels up to:
 not for fragrance use.
 
Recommendation for polydimethylsiloxanes flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):63148-62-9
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24705
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
dimethyl-bis(trimethylsilyloxy)silane
Chemidplus:0063148629
RTECS:JT6484500 for cas# 63148-62-9
 
References:
 dimethyl-bis(trimethylsilyloxy)silane
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:63148-62-9
Pubchem (cid):24705
Pubchem (sid):135263283
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C07261
HMDB (The Human Metabolome Database):Search
Export Tariff Code:3910.00.0000
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 baysilon
 dimethyl-bis(trimethylsilyloxy)silane
 polydimethylsiloxane (Mw > 6 800 Da)
 silicone oil for mp & bp apparatus
 
 
Notes:
None found
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