EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

potassium phosphate monobasic
phosphoric acid, potassium salt (1:1)

Sponsors

Name:potassium dihydrogen phosphate
CAS Number: 7778-77-0Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:231-913-4
FDA UNII:4J9FJ0HL51
MDL:MFCD00011401
Molecular Weight:136.08480200
Formula:H2 K O4 P
NMR Predictor:Predict (works with chrome or firefox)
Category:buffering agents, neutralizing agents, color fixatives, acidity regulators
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
1975 Potassium phosphate monobasic View-review
EU SANCO Potassium phosphates View-review
JECFA Food Additive: Potassium Dihydrogen Phosphate
GSFA Codex: Potassium dihydrogen phosphate (340(i))
DG SANTE Food Additives:potassium phosphate monobasic
FDA Mainterm: POTASSIUM PHOSPHATE, MONOBASIC
FDA Regulation:
FDA PART 101 -- FOOD LABELING
Subpart A--General Provisions
Sec. 101.9 Nutrition labeling of food.


FDA PART 160 -- EGGS AND EGG PRODUCTS
Subpart B--Requirements for Specific Standardized Eggs and Egg Products
Sec. 160.110 Frozen eggs.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.
 
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Insoluble in:
 alcohol
 
Organoleptic Properties:
Odor Description:at 100.00 %. odorless
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: buffering agents
 
Suppliers:
Allan Chemical
Potassium Phosphate Monobasic
American Elements
Potassium Phosphate 99%
Odor: characteristic
Use: Potassium Phosphate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
Monopotassium Phosphate
BOC Sciences
For experimental / research use only.
Buffer Salt, pH 6.86 95%
Charkit Chemical
POTASSIUM PHOSPHATE MONOBASIC ACS,USP-NF/FCC
Charkit Chemical
POTASSIUM PHOSPHATE, MONOBASIC
Covalent Chemical
Mono-potassium Phosphate
ECSA Chemicals
monoPotassium Phosphate
Company Profile
Foodchem International
Monopotassium Phosphate
Graham Chemical
MonoPotassium Phosphate
Jost Chemical
Potassium Phosphate Monobasic ACS Crystals
Jost Chemical
Potassium Phosphate Monobasic ACS Powder
Jost Chemical
Potassium Phosphate Monobasic NF Crystals
Jost Chemical
Potassium Phosphate Monobasic NF Powder
Penta International
POTASSIUM PHOSPHATE MONOBASIC CRYSTAL
Prinova
Monopotassium Phosphate
Qingdao Dacon Trading
Monopotassium Phosphate
Sigma-Aldrich: Aldrich
For experimental / research use only.
Potassium phosphate monobasic 99.99%
Wedor Corporation
POTASSIUM PHOSPHATE - MONOBASIC
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LDLo 4640 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: OTHER CHANGES
National Technical Information Service. Vol. OTS0571153

Dermal Toxicity:
skin-rabbit LD50 > 4640 mg/kg
National Technical Information Service. Vol. OTS0571153

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: buffering agents, neutralizing agents, color fixatives, acidity regulators
Recommendation for potassium phosphate monobasic usage levels up to:
 not for fragrance use.
 
Recommendation for potassium phosphate monobasic flavor usage levels up to:
 not for flavor use.
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Assessment of one published review on health risks associated with phosphate additives in food
View page or View pdf

EPI System: View
ClinicalTrials.gov:search
Daily Med:search
NIOSH International Chemical Safety Cards:search
NLM Hazardous Substances Data Bank:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):7778-77-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :516951
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
potassium dihydrogen phosphate
Chemidplus:0007778770
RTECS:7778-77-0
 
References:
 potassium dihydrogen phosphate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:7778-77-0
Pubchem (cid):516951
Pubchem (sid):134990611
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
FooDB:FDB013364
Export Tariff Code:2835.24.0000
Haz-Map:View
Household Products:Search
ChemSpider:View
Formulations/Preparations:
•injection, 4.4 meq of potassium ion and 3 mm of phosphorus (provided by potassium phosphate, monobasic 224 mg and potassium phosphate, dibasic 236 mgml. •grades: technical, cp, fcc (food chemicals codex) •first choice foliar supreme fungucide (loveland products, inc.) potassium phosphate, monobasic 31.1%, sulfur 31.1% •ekspunge (lidochem, inc.) potassium phosphate, monobasic 100% •first choice phortress fungicide (loveland products, inc.) potassium phosphate, monobasic 40.8%, mono- and di- potassium salts of phosphorous acid 28.1%
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 buffering agents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 phosphoric acid potassium salt (1:1)
 phosphoric acid, monopotassium salt
 phosphoric acid, potassium salt
 phosphoric acid, potassium salt (1:1)
 potassium dihydrogen orthophosphate
 potassium dihydrogen phosphate
monopotassium dihydrogen phosphate
 potassium dihydrogenorthophosphate
 potassium hydrogen phosphate (KH2PO4)
monopotassium monophosphate
monopotassium orthophosphate
monobasic potassium phosphate
 potassium phosphate, monobasic
 sorensen's potassium phosphate
 

Articles:

PubMed:Pharmacokinetics of dronedarone in rat using a newly developed high-performance liquid chromatographic assay method.
PubMed:Mobility and bioavailability reduction of soil TNT via sorption enhancement using monopotassium phosphate.
PubMed:[Validation of a liquid chromatography method for rifampicin determination in human plasma].
PubMed:Bromination of aromatic compounds by residual bromide in sodium chloride matrix modifier salt during heated headspace GC/MS analysis.
PubMed:A Single Gradient Stability-Indicating Reversed-Phase LC Method for the Estimation of Impurities in Omeprazole and Domperidone Capsules.
PubMed:Development and validation of a stability-indicating size-indicating size-exclusion LC method for the determination of rhIFN-alpha2a in pharmaceutical formulations.
PubMed:Estimation of standardized phosphorus retention for inorganic phosphate sources in broilers.
PubMed:Simultaneous determination of morniflumate and its major active metabolite, niflumic acid, in human plasma by high-performance liquid chromatography in stability and pharmacokinetic studies.
PubMed:Vacuum foam drying: an alternative to lyophilization for biomolecule preservation.
PubMed:Photodegradation kinetics, cytotoxicity assay and determination by stability-indicating HPLC method of mianserin hydrochloride.
PubMed:Cloning, purification, crystallization and preliminary X-ray crystallographic analysis of a cyclophilin A-like protein from Piriformospora indica.
PubMed:Development and validation of a rapid HPLC method for simultaneous analysis of budesonide and its novel synthesized hemiesters in colon specific formulations.
PubMed:Development and validation of a reversed-phase column liquid chromatographic method for the determination of five cephalosporins in pharmaceutical preparations.
PubMed:Intrinsically fluorescent carbon dots with tunable emission derived from hydrothermal treatment of glucose in the presence of monopotassium phosphate.
PubMed:Development and validation of an HPLC method for mefloquine hydrochloride determination in tablet dosage form.
PubMed:Partition Efficiency of High-Pitch Locular Multilayer Coil for Countercurrent Chromatographic Separation of Proteins Using Small-Scale Cross-Axis Coil Planet Centrifuge and Application to Purification of Various Collagenases with Aqueous-Aqueous Polymer Phase Systems.
PubMed:Application of liquid-liquid-liquid microextraction and high-performance liquid chromatography for the determination of alkylphenols and bisphenol-A in water.
PubMed:Rapid determination of paeoniflorin from Paeonia sinjiang K. Y. Pan. by rapid resolution liquid chromatography.
PubMed:Chitosan-dibasic orthophosphate hydrogel: a potential drug delivery system.
PubMed:Countercurrent chromatographic separation and purification of various ribonucleases using a small-scale cross-axis coil planet centrifuge with aqueous-aqueous polymer phase systems.
PubMed:[Effects of different forms of P fertilizers on phytoremediation for As-contaminated soils using As-hyperaccumulator Pteris vittata L].
PubMed:Validation of a model for growth of Lactococcus lactis and Listeria innocua in a structured gel system: effect of monopotassium phosphate.
PubMed:HPLC detection of marker compounds during buccal permeation enhancement studies.
PubMed:Determination of pitavastatin from human plasma using high performance liquid chromatography with fluorescence detection.
PubMed:New small-scale cross-axis coil planet centrifuge. Partition efficiency and application to purification of bullfrog ribonuclease.
PubMed:Determination of olanzapine in human plasma by reversed-phase high-performance liquid chromatography with ultraviolet detection.
PubMed:Doubling calcium and phosphate concentrations in neonatal parenteral nutrition solutions using monobasic potassium phosphate.
PubMed:Simultaneous determination of chlorpheniramine maleate and dexamethasone in a tablet dosage form by liquid chromatography.
PubMed:Determination of albuterol sulfate and its related substances in albuterol sulfate inhalation solution, 0.5% by RP-HPLC.
PubMed:Development and validation of a new HPLC method for determination of lamotrigine and related compounds in tablet formulations.
PubMed:A stability-indicating HPLC assay for metronidazole benzoate.
PubMed:Occlusion of dentin tubules by desensitizing agents.
PubMed:Assay for the simultaneous determination of acetaminophen-caffeine-butalbital in human serum using a monolithic column.
PubMed:[Determination of synthetic food dyes in food by capillary electrophoresis].
PubMed:Liquid chromatography determination of the anti-androgen vinclozolin and its metabolites in rat serum.
PubMed:Mineralization of dentin induced by treatment with bioactive glass S53P4 in vitro.
PubMed:Validation of a simple liquid chromatography assay for creatine suitable for pharmacokinetic applications, determination of plasma protein binding and verification of percent labeled claim of various creatine products.
PubMed:Development of a HPLC method for the determination of cyclosporin-A in rat blood and plasma using naproxen as an internal standard.
PubMed:LC method for the determination of oxcarbazepine in pharmaceutical preparations.
PubMed:The Ca/P range of nanoapatitic calcium phosphate cements.
PubMed:[RP-HPLC determination of adenosine in fermented Cordyceps].
PubMed:Optimization of nisin production by Lactococcus lactis.
PubMed:[Determination of nitidine in different parts of Zanthoxylum nitidum].
PubMed:High-performance liquid chromatography assay of amiodarone in rat plasma.
PubMed:Experimental study of phosphopeptide in promoting tooth remineralization.
PubMed:Adsorption characteristics of proteins on calcium phosphates using liquid chromatography.
PubMed:Validation of a method for the determination of zolpidem in human plasma using LC with fluorescence detection.
PubMed:Determination of histidine and related compounds in rumen fluid by liquid chromatography.
PubMed:Inositol hexaphosphate (IP6) as an anti-neoplastic and lipid-lowering agent.
PubMed:Stability-indicating high-performance liquid chromatographic assay of buspirone HCl.
PubMed:Bacillus stearothermophilus sporulation response to different composition media.
PubMed:A split-mouth placebo-controlled study to determine the effect of amorphous calcium phosphate in the treatment of dentine hypersensitivity.
PubMed:Determination of a new polymer-bound paclitaxel derivative (PNU 166945), free paclitaxel and 7-epipaclitaxel in dog plasma and urine by reversed-phase high-performance liquid chromatography with UV detection.
PubMed:High performance liquid chromatographic determination of folic acid and its photodegradation products in the presence of riboflavin.
PubMed:Simultaneous determination of the new anticancer agent amidox and its metabolites in rat bile and plasma by high-performance liquid chromatography.
PubMed:Determination of metronidazole in vaginal tissue by high-performance liquid chromatography using solid-phase extraction.
PubMed:Adsorption of [3H]-lipoteichoic acid to hydroxyapatite and its effect on crystal growth.
PubMed:Development and validation of a high-performance liquid chromatographic method for the determination of methocarbamol in human plasma.
PubMed:Determination of 5-fluorouracil and its main metabolites in plasma by high-performance liquid chromatography.
PubMed:Simple high-performance liquid chromatographic method for the determination of PGT/1A, a new immunostimulating drug, in biological fluids.
PubMed:Quantitation of urinary chlorobenzene metabolites by HPLC: concentrations of 4-chlorocatechol and chlorophenols in urine and of chlorobenzene in biological specimens of subjects exposed to chlorobenzene.
PubMed:Role of the source of phosphate salt in improving the mineral balance of parenterally fed low birth weight infants.
PubMed:High-performance liquid chromatographic analysis of doxacurium, a new long-acting neuromuscular blocker.
PubMed:Liquid chromatographic determination of penicillin V potassium in tablets: collaborative study.
PubMed:Assay of free and total tocainide by high performance liquid chromatography (HPLC) with ultraviolet (UV) detection.
PubMed:Simple and rapid reversed-phase high-performance liquid chromatographic determination of baclofen in human plasma with ultraviolet detection. Application to a pharmacokinetic study.
PubMed:High-performance liquid chromatographic assay of the aldose reductase inhibitor spiro-(2-fluoro-9H-fluorene-9,4'-imidazolidine)-2',5'-dione (AL01567) in plasma and urine and its pharmacokinetics in humans.
PubMed:A simple, fast and reliable method for obtaining dopamine histofluorescence from mesencephalic cultures.
PubMed:Simultaneous determination of urinary creatinine and metabolites of toluene, xylene, styrene, ethylbenzene and phenol by automated high performance liquid chromatography.
PubMed:Determination of terbutaline sulfate in dosage forms by liquid chromatography with electrochemical detection.
PubMed:Calcium and phosphate solubility in neonatal parenteral nutrient solutions containing Aminosyn PF.
PubMed:Effect of buffers on testing of Candida species susceptibility to flucytosine.
PubMed:Quantitation of urinary metabolites of toluene, xylene, styrene, ethylbenzene, benzene and phenol by automated high performance liquid chromatography.
PubMed:Liquid chromatographic determination of penicillin V potassium in tablets and powders for oral solution.
PubMed:Calcium and phosphate solubility in neonatal parenteral nutrient solutions containing TrophAmine.
PubMed:Reverse phase liquid chromatographic determination of sulfathiazole residues in honey.
PubMed:Simultaneous high-performance liquid chromatographic determination of theophylline, ephedrine hydrochloride, and phenobarbital in tablets.
PubMed:Efficacy of intravenous phosphorus therapy in the severely hypophosphatemic patient.
PubMed:Limulus amoebocyte lysate assay for detection and quantitation of endotoxin in a small-volume parenteral product.
PubMed:A liquid medium for the production of Kabatiella zeae conidia.
PubMed:Reverse phase high pressure liquid chromatographic determination of some iodoamino acid contaminants in sodium liothyronine or sodium levothyroxine.
PubMed:Balance of net base in the rat. IV. Effects of oral calcium and phosphate loading.
PubMed:Fluoride content of dental plaque before, during and after ingestion of sucrose modified with fluoride or bicarbonate-phosphate.
PubMed:Bacterial growth inhibition by amniotic fluid. IV. Studies on the nature of bacterial inhibition with the use of plate-count determinations.
PubMed:[Studies on murine leprosy bacillus. V. Growth in relation to concentrations of monopotassium phosphate, sodium glutamate and glycerol in the 1 per cent egg yolk medium, and in relation to pH of the medium].
PubMed:Studies on the murine leprosy bacillus. V. Growth in relation to concentrations of monopotassium phosphate, sodium glutamate, and glycerol in the 1 per cent egg yolk medium, and relation to pH of the medium.
 
Notes:
Buffering agent; acidulant; leavening agent; nutrient source
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