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Category:buffering agents, neutralizing agents, color fixatives, acidity regulators
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white crystalline powder (est) |
| Assay: | 98.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 1e+006 mg/L @ 25 °C (est) |
| Insoluble in: |
| | alcohol |
Organoleptic Properties:
| Odor Description:at 100.00 %. odorless |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LDLo 4640 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: OTHER CHANGES
National Technical Information Service. Vol. OTS0571153
|
| Dermal Toxicity: |
skin-rabbit LD50 > 4640 mg/kg
National Technical Information Service. Vol. OTS0571153
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| Inhalation Toxicity: |
|
Not determined
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Safety in Use Information:
| Category: | buffering agents, neutralizing agents, color fixatives, acidity regulators |
| Recommendation for potassium phosphate monobasic usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for potassium phosphate monobasic flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
European Food Safety Authority (EFSA) reference(s):
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Assessment of one published review on health risks associated with phosphate additives in food
View page or View pdf
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Re-evaluation of phosphoric acid–phosphates – di-, tri- and polyphosphates (E 338–341, E 343, E 450–452) as food additives and the safety of proposed extension of use
View page or View pdf
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| EPI System: View |
| ClinicalTrials.gov:search |
| Daily Med:search |
| NIOSH International Chemical Safety Cards:search |
| NLM Hazardous Substances Data Bank:Search |
| Env. Mutagen Info. Center:Search |
| NLM Developmental and Reproductive Toxicity:Search |
| EPA Substance Registry Services (TSCA):7778-77-0 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :516951 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:1 |
| potassium dihydrogen phosphate |
| Chemidplus:0007778770 |
| RTECS:7778-77-0 |
References:
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2009 |
| (IUPAC): | Atomic Weights of the Elements 2009 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | Search |
| FooDB: | FDB013364 |
| Export Tariff Code: | 2835.24.0000 |
| FDA Listing of Food Additive Status: | View |
| Haz-Map: | View |
| Household Products: | Search |
| ChemSpider: | View |
Formulations/Preparations:
•injection, 4.4 meq of potassium ion and 3 mm of phosphorus (provided by potassium phosphate, monobasic 224 mg and potassium phosphate, dibasic 236 mgml.
•grades: technical, cp, fcc (food chemicals codex)
•first choice foliar supreme fungucide (loveland products, inc.) potassium phosphate, monobasic 31.1%, sulfur 31.1%
•ekspunge (lidochem, inc.) potassium phosphate, monobasic 100%
•first choice phortress fungicide (loveland products, inc.) potassium phosphate, monobasic 40.8%, mono- and di- potassium salts of phosphorous acid 28.1%
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Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | phosphoric acid potassium salt (1:1) | | | phosphoric acid, monopotassium salt | | | phosphoric acid, potassium salt | | | phosphoric acid, potassium salt (1:1) | | | potassium dihydrogen orthophosphate | | | potassium dihydrogen phosphate | | mono | potassium dihydrogen phosphate | | | potassium dihydrogenorthophosphate | | | potassium hydrogen phosphate (KH2PO4) | | mono | potassium monophosphate | | mono | potassium orthophosphate | | monobasic | potassium phosphate | | | potassium phosphate, monobasic | | | sorensen's potassium phosphate |
Articles:
| PubMed:Pharmacokinetics of dronedarone in rat using a newly developed high-performance liquid chromatographic assay method. |
| PubMed:Mobility and bioavailability reduction of soil TNT via sorption enhancement using monopotassium phosphate. |
| PubMed:[Validation of a liquid chromatography method for rifampicin determination in human plasma]. |
| PubMed:Bromination of aromatic compounds by residual bromide in sodium chloride matrix modifier salt during heated headspace GC/MS analysis. |
| PubMed:A Single Gradient Stability-Indicating Reversed-Phase LC Method for the Estimation of Impurities in Omeprazole and Domperidone Capsules. |
| PubMed:Development and validation of a stability-indicating size-indicating size-exclusion LC method for the determination of rhIFN-alpha2a in pharmaceutical formulations. |
| PubMed:Estimation of standardized phosphorus retention for inorganic phosphate sources in broilers. |
| PubMed:Simultaneous determination of morniflumate and its major active metabolite, niflumic acid, in human plasma by high-performance liquid chromatography in stability and pharmacokinetic studies. |
| PubMed:Vacuum foam drying: an alternative to lyophilization for biomolecule preservation. |
| PubMed:Photodegradation kinetics, cytotoxicity assay and determination by stability-indicating HPLC method of mianserin hydrochloride. |
| PubMed:Cloning, purification, crystallization and preliminary X-ray crystallographic analysis of a cyclophilin A-like protein from Piriformospora indica. |
| PubMed:Development and validation of a rapid HPLC method for simultaneous analysis of budesonide and its novel synthesized hemiesters in colon specific formulations. |
| PubMed:Development and validation of a reversed-phase column liquid chromatographic method for the determination of five cephalosporins in pharmaceutical preparations. |
| PubMed:Intrinsically fluorescent carbon dots with tunable emission derived from hydrothermal treatment of glucose in the presence of monopotassium phosphate. |
| PubMed:Development and validation of an HPLC method for mefloquine hydrochloride determination in tablet dosage form. |
| PubMed:Partition Efficiency of High-Pitch Locular Multilayer Coil for Countercurrent Chromatographic Separation of Proteins Using Small-Scale Cross-Axis Coil Planet Centrifuge and Application to Purification of Various Collagenases with Aqueous-Aqueous Polymer Phase Systems. |
| PubMed:Application of liquid-liquid-liquid microextraction and high-performance liquid chromatography for the determination of alkylphenols and bisphenol-A in water. |
| PubMed:Rapid determination of paeoniflorin from Paeonia sinjiang K. Y. Pan. by rapid resolution liquid chromatography. |
| PubMed:Chitosan-dibasic orthophosphate hydrogel: a potential drug delivery system. |
| PubMed:Countercurrent chromatographic separation and purification of various ribonucleases using a small-scale cross-axis coil planet centrifuge with aqueous-aqueous polymer phase systems. |
| PubMed:[Effects of different forms of P fertilizers on phytoremediation for As-contaminated soils using As-hyperaccumulator Pteris vittata L]. |
| PubMed:Validation of a model for growth of Lactococcus lactis and Listeria innocua in a structured gel system: effect of monopotassium phosphate. |
| PubMed:HPLC detection of marker compounds during buccal permeation enhancement studies. |
| PubMed:Determination of pitavastatin from human plasma using high performance liquid chromatography with fluorescence detection. |
| PubMed:New small-scale cross-axis coil planet centrifuge. Partition efficiency and application to purification of bullfrog ribonuclease. |
| PubMed:Determination of olanzapine in human plasma by reversed-phase high-performance liquid chromatography with ultraviolet detection. |
| PubMed:Doubling calcium and phosphate concentrations in neonatal parenteral nutrition solutions using monobasic potassium phosphate. |
| PubMed:Simultaneous determination of chlorpheniramine maleate and dexamethasone in a tablet dosage form by liquid chromatography. |
| PubMed:Determination of albuterol sulfate and its related substances in albuterol sulfate inhalation solution, 0.5% by RP-HPLC. |
| PubMed:Development and validation of a new HPLC method for determination of lamotrigine and related compounds in tablet formulations. |
| PubMed:A stability-indicating HPLC assay for metronidazole benzoate. |
| PubMed:Occlusion of dentin tubules by desensitizing agents. |
| PubMed:Assay for the simultaneous determination of acetaminophen-caffeine-butalbital in human serum using a monolithic column. |
| PubMed:[Determination of synthetic food dyes in food by capillary electrophoresis]. |
| PubMed:Liquid chromatography determination of the anti-androgen vinclozolin and its metabolites in rat serum. |
| PubMed:Mineralization of dentin induced by treatment with bioactive glass S53P4 in vitro. |
| PubMed:Validation of a simple liquid chromatography assay for creatine suitable for pharmacokinetic applications, determination of plasma protein binding and verification of percent labeled claim of various creatine products. |
| PubMed:Development of a HPLC method for the determination of cyclosporin-A in rat blood and plasma using naproxen as an internal standard. |
| PubMed:LC method for the determination of oxcarbazepine in pharmaceutical preparations. |
| PubMed:The Ca/P range of nanoapatitic calcium phosphate cements. |
| PubMed:[RP-HPLC determination of adenosine in fermented Cordyceps]. |
| PubMed:Optimization of nisin production by Lactococcus lactis. |
| PubMed:[Determination of nitidine in different parts of Zanthoxylum nitidum]. |
| PubMed:High-performance liquid chromatography assay of amiodarone in rat plasma. |
| PubMed:Experimental study of phosphopeptide in promoting tooth remineralization. |
| PubMed:Adsorption characteristics of proteins on calcium phosphates using liquid chromatography. |
| PubMed:Validation of a method for the determination of zolpidem in human plasma using LC with fluorescence detection. |
| PubMed:Determination of histidine and related compounds in rumen fluid by liquid chromatography. |
| PubMed:Inositol hexaphosphate (IP6) as an anti-neoplastic and lipid-lowering agent. |
| PubMed:Stability-indicating high-performance liquid chromatographic assay of buspirone HCl. |
| PubMed:Bacillus stearothermophilus sporulation response to different composition media. |
| PubMed:A split-mouth placebo-controlled study to determine the effect of amorphous calcium phosphate in the treatment of dentine hypersensitivity. |
| PubMed:Determination of a new polymer-bound paclitaxel derivative (PNU 166945), free paclitaxel and 7-epipaclitaxel in dog plasma and urine by reversed-phase high-performance liquid chromatography with UV detection. |
| PubMed:High performance liquid chromatographic determination of folic acid and its photodegradation products in the presence of riboflavin. |
| PubMed:Simultaneous determination of the new anticancer agent amidox and its metabolites in rat bile and plasma by high-performance liquid chromatography. |
| PubMed:Determination of metronidazole in vaginal tissue by high-performance liquid chromatography using solid-phase extraction. |
| PubMed:Adsorption of [3H]-lipoteichoic acid to hydroxyapatite and its effect on crystal growth. |
| PubMed:Development and validation of a high-performance liquid chromatographic method for the determination of methocarbamol in human plasma. |
| PubMed:Determination of 5-fluorouracil and its main metabolites in plasma by high-performance liquid chromatography. |
| PubMed:Simple high-performance liquid chromatographic method for the determination of PGT/1A, a new immunostimulating drug, in biological fluids. |
| PubMed:Quantitation of urinary chlorobenzene metabolites by HPLC: concentrations of 4-chlorocatechol and chlorophenols in urine and of chlorobenzene in biological specimens of subjects exposed to chlorobenzene. |
| PubMed:Role of the source of phosphate salt in improving the mineral balance of parenterally fed low birth weight infants. |
| PubMed:High-performance liquid chromatographic analysis of doxacurium, a new long-acting neuromuscular blocker. |
| PubMed:Liquid chromatographic determination of penicillin V potassium in tablets: collaborative study. |
| PubMed:Assay of free and total tocainide by high performance liquid chromatography (HPLC) with ultraviolet (UV) detection. |
| PubMed:Simple and rapid reversed-phase high-performance liquid chromatographic determination of baclofen in human plasma with ultraviolet detection. Application to a pharmacokinetic study. |
| PubMed:High-performance liquid chromatographic assay of the aldose reductase inhibitor spiro-(2-fluoro-9H-fluorene-9,4'-imidazolidine)-2',5'-dione (AL01567) in plasma and urine and its pharmacokinetics in humans. |
| PubMed:A simple, fast and reliable method for obtaining dopamine histofluorescence from mesencephalic cultures. |
| PubMed:Simultaneous determination of urinary creatinine and metabolites of toluene, xylene, styrene, ethylbenzene and phenol by automated high performance liquid chromatography. |
| PubMed:Determination of terbutaline sulfate in dosage forms by liquid chromatography with electrochemical detection. |
| PubMed:Calcium and phosphate solubility in neonatal parenteral nutrient solutions containing Aminosyn PF. |
| PubMed:Effect of buffers on testing of Candida species susceptibility to flucytosine. |
| PubMed:Quantitation of urinary metabolites of toluene, xylene, styrene, ethylbenzene, benzene and phenol by automated high performance liquid chromatography. |
| PubMed:Liquid chromatographic determination of penicillin V potassium in tablets and powders for oral solution. |
| PubMed:Calcium and phosphate solubility in neonatal parenteral nutrient solutions containing TrophAmine. |
| PubMed:Reverse phase liquid chromatographic determination of sulfathiazole residues in honey. |
| PubMed:Simultaneous high-performance liquid chromatographic determination of theophylline, ephedrine hydrochloride, and phenobarbital in tablets. |
| PubMed:Efficacy of intravenous phosphorus therapy in the severely hypophosphatemic patient. |
| PubMed:Limulus amoebocyte lysate assay for detection and quantitation of endotoxin in a small-volume parenteral product. |
| PubMed:A liquid medium for the production of Kabatiella zeae conidia. |
| PubMed:Reverse phase high pressure liquid chromatographic determination of some iodoamino acid contaminants in sodium liothyronine or sodium levothyroxine. |
| PubMed:Balance of net base in the rat. IV. Effects of oral calcium and phosphate loading. |
| PubMed:Fluoride content of dental plaque before, during and after ingestion of sucrose modified with fluoride or bicarbonate-phosphate. |
| PubMed:Bacterial growth inhibition by amniotic fluid. IV. Studies on the nature of bacterial inhibition with the use of plate-count determinations. |
| PubMed:[Studies on murine leprosy bacillus. V. Growth in relation to concentrations of monopotassium phosphate, sodium glutamate and glycerol in the 1 per cent egg yolk medium, and in relation to pH of the medium]. |
| PubMed:Studies on the murine leprosy bacillus. V. Growth in relation to concentrations of monopotassium phosphate, sodium glutamate, and glycerol in the 1 per cent egg yolk medium, and relation to pH of the medium. |
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3D/inchi