potassium phosphate monobasic
phosphoric acid, potassium salt (1:1)
Buffering agent; acidulant; leavening agent; nutrient source
  • American International Chemical, LLC.
    • American International Chemical, Inc.
      Consistent sources
      North American supplier for globally sourced ingredients.
      AIC is a Framingham, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of 30 Sales Representatives, along with our 19 strategically located warehouses are ready to supply product when and where you need it.
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      MKPCMF Monopotassium Phosphate
  • Charkit Chemical
    • Charkit Chemical Corporation
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      Explore this website to discover the products and services that Charkit provides for your industry and please contact us directly to find out how we can be of service to you.
      Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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  • ECSA Chemicals
    • ECSA Chemicals
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      A hundred years on from its establishment, the Emanuele Centonze Holding SA has developed a solid presence in Switzerland and in Europe. The Group currently includes: ECSA Chemicals AG/ECSA Italia SRL SocietÓ con Unico Socio – ECSA Maintenance AG – ECSA Energy SA – Porta Ticino Easy Stop SA. The Group operates in the distribution of chemical and petroleum products, in the international trading of commodities, and in the distribution of maintenance systems. With 285 employees, a consolidated turnover of 335 million Swiss Francs in 2015, and more than 15,000 active customers, the Group ranks among the top 500 companies in Switzerland. ECSA operates in Switzerland and the EU, and in particular has consolidated its geographical position on the main axis linking northern and southern Europe, thus creating a competitive and privileged logistical hub.
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      monoPotassium Phosphate
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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potassium dihydrogen phosphate (Click)
CAS Number: 7778-77-0Picture of molecule
ECHA EINECS - REACH Pre-Reg: 231-913-4
MDL: MFCD00011401
Molecular Weight: 136.08480200
Formula: H2 K O4 P
NMR Predictor: Predict (works with chrome or firefox)
Category: buffering agents, neutralizing agents, color fixatives, acidity regulators
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
 FDA/DG SANTE Petitions, Reviews, Notices:
1975 Potassium phosphate monobasic View-review
EU SANCO Potassium phosphates View-review
JECFA Food Additive: Potassium Dihydrogen Phosphate
GSFA Codex: Potassium dihydrogen phosphate (340(i))
DG SANTE Food Additives: potassium phosphate monobasic
FDA Regulation:
Subpart A--General Provisions
Sec. 101.9 Nutrition labeling of food.

Subpart B--Requirements for Specific Standardized Eggs and Egg Products
Sec. 160.110 Frozen eggs.

Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.
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Physical Properties:
Appearance: white crystalline powder (est)
Assay: 98.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Insoluble in:
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Organoleptic Properties:
Odor Description:
at 100.00 %. 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: buffering agents
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Allan Chemical
Potassium Phosphate Monobasic
American Elements
Potassium Phosphate 99%
Odor: characteristic
Use: Potassium Phosphate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
Monopotassium Phosphate
Charkit Chemical
Charkit Chemical
Covalent Chemical
Mono-potassium Phosphate
ECSA Chemicals
monoPotassium Phosphate
Company Profile
Foodchem International
Monopotassium Phosphate
Graham Chemical
MonoPotassium Phosphate
Jost Chemical
Potassium Phosphate Monobasic ACS Crystals
Jost Chemical
Potassium Phosphate Monobasic ACS Powder
Jost Chemical
Potassium Phosphate Monobasic NF Crystals
Jost Chemical
Potassium Phosphate Monobasic NF Powder
Lianyungang Yunbo Chemical
Penta International
Monopotassium Phosphate
Qingdao Dacon Trading
Monopotassium Phosphate
Sigma-Aldrich: Aldrich
For experimental / research use only.
Potassium phosphate monobasic 99.99%
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Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LDLo  4640 mg/kg
National Technical Information Service. Vol. OTS0571153

Dermal Toxicity:
skin-rabbit LD50 > 4640 mg/kg
National Technical Information Service. Vol. OTS0571153

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: buffering agents, neutralizing agents, color fixatives, acidity regulators
Recommendation for potassium phosphate monobasic usage levels up to:
 not for fragrance use.
Recommendation for potassium phosphate monobasic flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Assessment of one published review on health risks associated with phosphate additives in food
View page or View pdf
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
NIOSH International Chemical Safety Cards: search
NLM Hazardous Substances Data Bank: Search
Env. Mutagen Info. Center: Search
NLM Developmental and Reproductive Toxicity: Search
EPA Substance Registry Services (TSCA): 7778-77-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 516951
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 potassium dihydrogen phosphate
Chemidplus: 0007778770
RTECS: 7778-77-0
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 potassium dihydrogen phosphate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 7778-77-0
Pubchem (cid): 516951
Pubchem (sid): 134990611
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
HMDB (The Human Metabolome Database): Search
FooDB: FDB013364
Export Tariff Code: 2835.24.0000
Haz-Map: View
Household Products: Search
ChemSpider: View
•injection, 4.4 meq of potassium ion and 3 mm of phosphorus (provided by potassium phosphate, monobasic 224 mg and potassium phosphate, dibasic 236 mgml. •grades: technical, cp, fcc (food chemicals codex) •first choice foliar supreme fungucide (loveland products, inc.) potassium phosphate, monobasic 31.1%, sulfur 31.1% •ekspunge (lidochem, inc.) potassium phosphate, monobasic 100% •first choice phortress fungicide (loveland products, inc.) potassium phosphate, monobasic 40.8%, mono- and di- potassium salts of phosphorous acid 28.1%
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Potential Blenders and core components note
None Found
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Potential Uses:
 buffering agents 
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Occurrence (nature, food, other): note
 not found in nature
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 phosphoric acid potassium salt (1:1)
 phosphoric acid, monopotassium salt
 phosphoric acid, potassium salt
 phosphoric acid, potassium salt (1:1)
 potassium dihydrogen orthophosphate
 potassium dihydrogen phosphate
monopotassium dihydrogen phosphate
 potassium dihydrogenorthophosphate
 potassium hydrogen phosphate (KH2PO4)
monopotassium monophosphate
monopotassium orthophosphate
monobasic potassium phosphate
 potassium phosphate, monobasic
 sorensen's potassium phosphate
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PubMed: Pharmacokinetics of dronedarone in rat using a newly developed high-performance liquid chromatographic assay method.
PubMed: Mobility and bioavailability reduction of soil TNT via sorption enhancement using monopotassium phosphate.
PubMed: [Validation of a liquid chromatography method for rifampicin determination in human plasma].
PubMed: Bromination of aromatic compounds by residual bromide in sodium chloride matrix modifier salt during heated headspace GC/MS analysis.
PubMed: A Single Gradient Stability-Indicating Reversed-Phase LC Method for the Estimation of Impurities in Omeprazole and Domperidone Capsules.
PubMed: Development and validation of a stability-indicating size-indicating size-exclusion LC method for the determination of rhIFN-alpha2a in pharmaceutical formulations.
PubMed: Estimation of standardized phosphorus retention for inorganic phosphate sources in broilers.
PubMed: Simultaneous determination of morniflumate and its major active metabolite, niflumic acid, in human plasma by high-performance liquid chromatography in stability and pharmacokinetic studies.
PubMed: Vacuum foam drying: an alternative to lyophilization for biomolecule preservation.
PubMed: Photodegradation kinetics, cytotoxicity assay and determination by stability-indicating HPLC method of mianserin hydrochloride.
PubMed: Cloning, purification, crystallization and preliminary X-ray crystallographic analysis of a cyclophilin A-like protein from Piriformospora indica.
PubMed: Development and validation of a rapid HPLC method for simultaneous analysis of budesonide and its novel synthesized hemiesters in colon specific formulations.
PubMed: Development and validation of a reversed-phase column liquid chromatographic method for the determination of five cephalosporins in pharmaceutical preparations.
PubMed: Intrinsically fluorescent carbon dots with tunable emission derived from hydrothermal treatment of glucose in the presence of monopotassium phosphate.
PubMed: Development and validation of an HPLC method for mefloquine hydrochloride determination in tablet dosage form.
PubMed: Partition Efficiency of High-Pitch Locular Multilayer Coil for Countercurrent Chromatographic Separation of Proteins Using Small-Scale Cross-Axis Coil Planet Centrifuge and Application to Purification of Various Collagenases with Aqueous-Aqueous Polymer Phase Systems.
PubMed: Application of liquid-liquid-liquid microextraction and high-performance liquid chromatography for the determination of alkylphenols and bisphenol-A in water.
PubMed: Rapid determination of paeoniflorin from Paeonia sinjiang K. Y. Pan. by rapid resolution liquid chromatography.
PubMed: Chitosan-dibasic orthophosphate hydrogel: a potential drug delivery system.
PubMed: Countercurrent chromatographic separation and purification of various ribonucleases using a small-scale cross-axis coil planet centrifuge with aqueous-aqueous polymer phase systems.
PubMed: [Effects of different forms of P fertilizers on phytoremediation for As-contaminated soils using As-hyperaccumulator Pteris vittata L].
PubMed: Validation of a model for growth of Lactococcus lactis and Listeria innocua in a structured gel system: effect of monopotassium phosphate.
PubMed: HPLC detection of marker compounds during buccal permeation enhancement studies.
PubMed: Determination of pitavastatin from human plasma using high performance liquid chromatography with fluorescence detection.
PubMed: New small-scale cross-axis coil planet centrifuge. Partition efficiency and application to purification of bullfrog ribonuclease.
PubMed: Determination of olanzapine in human plasma by reversed-phase high-performance liquid chromatography with ultraviolet detection.
PubMed: Doubling calcium and phosphate concentrations in neonatal parenteral nutrition solutions using monobasic potassium phosphate.
PubMed: Simultaneous determination of chlorpheniramine maleate and dexamethasone in a tablet dosage form by liquid chromatography.
PubMed: Determination of albuterol sulfate and its related substances in albuterol sulfate inhalation solution, 0.5% by RP-HPLC.
PubMed: Development and validation of a new HPLC method for determination of lamotrigine and related compounds in tablet formulations.
PubMed: A stability-indicating HPLC assay for metronidazole benzoate.
PubMed: Occlusion of dentin tubules by desensitizing agents.
PubMed: Assay for the simultaneous determination of acetaminophen-caffeine-butalbital in human serum using a monolithic column.
PubMed: [Determination of synthetic food dyes in food by capillary electrophoresis].
PubMed: Liquid chromatography determination of the anti-androgen vinclozolin and its metabolites in rat serum.
PubMed: Mineralization of dentin induced by treatment with bioactive glass S53P4 in vitro.
PubMed: Validation of a simple liquid chromatography assay for creatine suitable for pharmacokinetic applications, determination of plasma protein binding and verification of percent labeled claim of various creatine products.
PubMed: Development of a HPLC method for the determination of cyclosporin-A in rat blood and plasma using naproxen as an internal standard.
PubMed: LC method for the determination of oxcarbazepine in pharmaceutical preparations.
PubMed: The Ca/P range of nanoapatitic calcium phosphate cements.
PubMed: [RP-HPLC determination of adenosine in fermented Cordyceps].
PubMed: Optimization of nisin production by Lactococcus lactis.
PubMed: [Determination of nitidine in different parts of Zanthoxylum nitidum].
PubMed: High-performance liquid chromatography assay of amiodarone in rat plasma.
PubMed: Experimental study of phosphopeptide in promoting tooth remineralization.
PubMed: Adsorption characteristics of proteins on calcium phosphates using liquid chromatography.
PubMed: Validation of a method for the determination of zolpidem in human plasma using LC with fluorescence detection.
PubMed: Determination of histidine and related compounds in rumen fluid by liquid chromatography.
PubMed: Inositol hexaphosphate (IP6) as an anti-neoplastic and lipid-lowering agent.
PubMed: Stability-indicating high-performance liquid chromatographic assay of buspirone HCl.
PubMed: Bacillus stearothermophilus sporulation response to different composition media.
PubMed: A split-mouth placebo-controlled study to determine the effect of amorphous calcium phosphate in the treatment of dentine hypersensitivity.
PubMed: Determination of a new polymer-bound paclitaxel derivative (PNU 166945), free paclitaxel and 7-epipaclitaxel in dog plasma and urine by reversed-phase high-performance liquid chromatography with UV detection.
PubMed: High performance liquid chromatographic determination of folic acid and its photodegradation products in the presence of riboflavin.
PubMed: Simultaneous determination of the new anticancer agent amidox and its metabolites in rat bile and plasma by high-performance liquid chromatography.
PubMed: Determination of metronidazole in vaginal tissue by high-performance liquid chromatography using solid-phase extraction.
PubMed: Adsorption of [3H]-lipoteichoic acid to hydroxyapatite and its effect on crystal growth.
PubMed: Development and validation of a high-performance liquid chromatographic method for the determination of methocarbamol in human plasma.
PubMed: Determination of 5-fluorouracil and its main metabolites in plasma by high-performance liquid chromatography.
PubMed: Simple high-performance liquid chromatographic method for the determination of PGT/1A, a new immunostimulating drug, in biological fluids.
PubMed: Quantitation of urinary chlorobenzene metabolites by HPLC: concentrations of 4-chlorocatechol and chlorophenols in urine and of chlorobenzene in biological specimens of subjects exposed to chlorobenzene.
PubMed: Role of the source of phosphate salt in improving the mineral balance of parenterally fed low birth weight infants.
PubMed: High-performance liquid chromatographic analysis of doxacurium, a new long-acting neuromuscular blocker.
PubMed: Liquid chromatographic determination of penicillin V potassium in tablets: collaborative study.
PubMed: Assay of free and total tocainide by high performance liquid chromatography (HPLC) with ultraviolet (UV) detection.
PubMed: Simple and rapid reversed-phase high-performance liquid chromatographic determination of baclofen in human plasma with ultraviolet detection. Application to a pharmacokinetic study.
PubMed: High-performance liquid chromatographic assay of the aldose reductase inhibitor spiro-(2-fluoro-9H-fluorene-9,4'-imidazolidine)-2',5'-dione (AL01567) in plasma and urine and its pharmacokinetics in humans.
PubMed: A simple, fast and reliable method for obtaining dopamine histofluorescence from mesencephalic cultures.
PubMed: Simultaneous determination of urinary creatinine and metabolites of toluene, xylene, styrene, ethylbenzene and phenol by automated high performance liquid chromatography.
PubMed: Determination of terbutaline sulfate in dosage forms by liquid chromatography with electrochemical detection.
PubMed: Calcium and phosphate solubility in neonatal parenteral nutrient solutions containing Aminosyn PF.
PubMed: Effect of buffers on testing of Candida species susceptibility to flucytosine.
PubMed: Quantitation of urinary metabolites of toluene, xylene, styrene, ethylbenzene, benzene and phenol by automated high performance liquid chromatography.
PubMed: Liquid chromatographic determination of penicillin V potassium in tablets and powders for oral solution.
PubMed: Calcium and phosphate solubility in neonatal parenteral nutrient solutions containing TrophAmine.
PubMed: Reverse phase liquid chromatographic determination of sulfathiazole residues in honey.
PubMed: Simultaneous high-performance liquid chromatographic determination of theophylline, ephedrine hydrochloride, and phenobarbital in tablets.
PubMed: Efficacy of intravenous phosphorus therapy in the severely hypophosphatemic patient.
PubMed: Limulus amoebocyte lysate assay for detection and quantitation of endotoxin in a small-volume parenteral product.
PubMed: A liquid medium for the production of Kabatiella zeae conidia.
PubMed: Reverse phase high pressure liquid chromatographic determination of some iodoamino acid contaminants in sodium liothyronine or sodium levothyroxine.
PubMed: Balance of net base in the rat. IV. Effects of oral calcium and phosphate loading.
PubMed: Fluoride content of dental plaque before, during and after ingestion of sucrose modified with fluoride or bicarbonate-phosphate.
PubMed: Bacterial growth inhibition by amniotic fluid. IV. Studies on the nature of bacterial inhibition with the use of plate-count determinations.
PubMed: [Studies on murine leprosy bacillus. V. Growth in relation to concentrations of monopotassium phosphate, sodium glutamate and glycerol in the 1 per cent egg yolk medium, and in relation to pH of the medium].
PubMed: Studies on the murine leprosy bacillus. V. Growth in relation to concentrations of monopotassium phosphate, sodium glutamate, and glycerol in the 1 per cent egg yolk medium, and relation to pH of the medium.
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