polyethyloxazoline
poly(2-ethyl-2-oxazoline)
 
Notes:
used for the controlled release of drugs.
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2-ethyl-4,5-dihydro-1,3-oxazole (poly) (Click)
CAS Number: 25805-17-8Picture of molecule
Other: 114730-76-6
FDA UNII: S5DPG6K67I
MDL: MFCD00134377
Formula: (C5 H9 N O)x-
NMR Predictor: Predict (works with chrome or firefox)
Category: binding, film forming agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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NCBI: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 1.14000 @  25.00 °C.
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: absorbents
binding agents
film formers
hair fixing agents
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Suppliers:
Sigma-Aldrich: Aldrich
For experimental / research use only.
Poly(2-ethyl-2-oxazoline)
average Mw ∼50,000, PDI 3-4
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: binding, film forming agents
Recommendation for polyethyloxazoline usage levels up to:
 not for fragrance use.
 
Recommendation for polyethyloxazoline flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 66412
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 2-ethyl-4,5-dihydro-1,3-oxazole (poly)
Chemidplus: 0025805178
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References:
 2-ethyl-4,5-dihydro-1,3-oxazole (poly)
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 25805-17-8
Pubchem (cid): 66412
Pubchem (sid): 135226969
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 3909.30.0000
ChemSpider: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 poly(2-ethyl-2-oxazoline)
2-ethyl-4,5-dihydro-1,3-oxazole (poly)
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Articles:
PubMed: Comparative efficacy of blood cell immunocamouflage by membrane grafting of methoxypoly(ethylene glycol) and polyethyloxazoline.
PubMed: Paclitaxel and iron oxide loaded multifunctional nanoparticles for chemotherapy, fluorescence properties, and magnetic resonance imaging.
PubMed: Polymeric micelles with a pH-responsive structure as intracellular drug carriers.
PubMed: Non-viral-mediated gene therapy approaches for bone repair.
PubMed: Specific interactions study in complexes of poly(mono-n-alkyl itaconates) with tertiary polyamides.
PubMed: New amphiphilic poly(2-ethyl-2-oxazoline)/ poly(L-lactide) triblock copolymers.
PubMed: Polymeric micelles of poly(2-ethyl-2-oxazoline)-block-poly(epsilon-caprolactone) copolymer as a carrier for paclitaxel.
PubMed: DNA transfection using linear poly(ethylenimine) prepared by controlled acid hydrolysis of poly(2-ethyl-2-oxazoline).
PubMed: Electrically erodible polymer gel for controlled release of drugs.
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