dimethyl MEA
dimethylaminoethanol
 
Notes:
an antidepressive agent that has also been used in the treatment of movement disorders. the mechanism of action is not well understood. Used as a food additive [EAFUS]
  • Lansdowne Chemicals
    • Lansdowne Chemicals
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      Product(s):
      Dimethylethanolamine DEMA 99% Min.
       
  • TCI AMERICA
    • TCI AMERICA
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      Product(s):
      D0649 2-(Dimethylamino)ethanol >99.0%(GC)(T)
       
Synonyms   Articles   Notes   Search
2-(dimethylamino)ethanol (Click)
CAS Number: 108-01-0Picture of molecule
ECHA EINECS - REACH Pre-Reg: 203-542-8
FDA UNII: 2N6K9DRA24
Nikkaji Web: J5.068G
Beilstein Number: 1209235
MDL: MFCD00002846
XlogP3-AA: -0.40 (est)
Molecular Weight: 89.13787000
Formula: C4 H11 N O
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: food contact resinous and polymeric coatings
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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DG SANTE Food Contact Materials: dimethylaminoethanol
FDA Mainterm: DIMETHYLETHANOLAMINE
FDA Regulation:
FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart A--Polymer Substances and Polymer Adjuvants for Food Treatment
Sec. 173.20 Ion-exchange membranes.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.300 Resinous and polymeric coatings.
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Physical Properties:
Appearance: colorless to pale yellow clear liquid (est)
Food Chemicals Codex Listed: No
Specific Gravity: 0.88700 @  25.00 °C.
Refractive Index: 1.42940 @  20.00 °C.
Melting Point: -60.00 °C. @ 760.00 mm Hg
Boiling Point: 134.00 °C. @ 760.00 mm Hg
Boiling Point: 135.00 °C. @ 758.00 mm Hg
Vapor Pressure: 3.180000 mm/Hg @ 25.00 °C.
Flash Point: 105.00 °F. TCC ( 40.56 °C. )
logP (o/w): -0.328 (est)
Soluble in:
 water, 1000000 mg/L @ 25 °C (exp)
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: buffering agents
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Suppliers:
Amines & Plasticizers
Di Methyl Ethanolamine
Odor: characteristic
Use: Pharmaceuticals, Pesticides, Paints, ION - exchange resins and Corrosion Inhibitor.
Lansdowne Chemicals
Dimethylethanolamine DEMA 99% Min.
Maypro Industries
Dimethylaminoethanol
Santa Cruz Biotechnology
For experimental / research use only.
2-Dimethylaminoethanol ≥99%
Sigma-Aldrich: Aldrich
For experimental / research use only.
2-Dimethylaminoethanol ≥99.5%
Silver Fern Chemical
Dimethylethanolamine
Odor: characteristic
Use: Dimethylethanolamine is used as a curing agent for epoxy resins and polyurethanes. It is also used in the intermediate synthesis of dyestuffs, textiles, pharmaceuticals, and corrosion inhibitors. Another application is an emulsifier in paints and coatings.
Taminco (Eastman)
Amietol® M21
TCI AMERICA
For experimental / research use only.
2-(Dimethylamino)ethanol >99.0%(GC)(T)
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  2000 mg/kg
Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 393, 1974.

intraperitoneal-guinea pig LDLo  450 mg/kg
Proceedings of the Society for Experimental Biology and Medicine. Vol. 85, Pg. 642, 1954.

intraperitoneal-mouse LD50  234 mg/kg
BEHAVIORAL: ATAXIA
Journal of Pharmacology and Experimental Therapeutics. Vol. 94, Pg. 249, 1948.

intraperitoneal-rat LD50  1080 mg/kg
Toxicology and Applied Pharmacology. Vol. 12, Pg. 486, 1968.

Dermal Toxicity:
skin-rabbit LD50 1370 ul/kg
AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951.

subcutaneous-mouse LD50 961 mg/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: TREMOR BEHAVIORAL: COMA
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 225, Pg. 428, 1955.

Inhalation Toxicity:
inhalation-rat LC50 1641 ppm/4H
SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Fundamental and Applied Toxicology. Vol. 9, Pg. 512, 1987.

inhalation-mouse LC50 3250 mg/m3
SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 14(11), Pg. 52, 1970.

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Safety in Use Information:
Category: food contact resinous and polymeric coatings
Recommendation for dimethyl MEA usage levels up to:
 not for fragrance use.
 
Recommendation for dimethyl MEA flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
NIOSH International Chemical Safety Cards: search
NLM Hazardous Substances Data Bank: Search
Chemical Carcinogenesis Research Information System: Search
Cancer Citations: Search
Toxicology Citations: Search
Carcinogenic Potency Database: Search
Env. Mutagen Info. Center: Search
NLM Developmental and Reproductive Toxicity: Search
EPA Substance Registry Services (TSCA): 108-01-0
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 7902
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 2-(dimethylamino)ethanol
Chemidplus: 0000108010
EPA/NOAA CAMEO: hazardous materials
RTECS: 108-01-0
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References:
 2-(dimethylamino)ethanol
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 108-01-0
Pubchem (cid): 7902
Pubchem (sid): 134972747
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): D07777
HMDB (The Human Metabolome Database): HMDB32231
FooDB: FDB009311
Export Tariff Code: 2922.19.9519
Haz-Map: View
Household Products: Search
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Formulations/Preparations:
•tablet form consists of deanol acetamidobenzoate which is the p-acetamidobenzoic acid salt of 2-(dimethylamino)ethanol (deanol). deanol acetamidobenzoate •grades: anhydrous and 70% aqueous soln. •a component of methylene chloride paint and varnish removers at 1 wt%
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 deanol
2-dimethyl aminoethanol
N-dimethyl aminoethanol
N,N-dimethyl ethanol amine
N,N-dimethyl-2-aminoethanol
N,N-dimethyl-2-hydroxyethylamine
N,N-dimethyl-N-(2-hydroxyethyl)amine
N,N-dimethyl-N-ethanolamine.
 dimethyl(2-hydroxyethyl)amine
 dimethyl(hydroxyethyl)amine
2-dimethylamino-ethanol
2-(dimethylamino)-1-ethanol
2-(dimethylamino)ethan-1-ol
2-(dimethylamino)ethanol
2-(N,N-dimethylamino)ethanol
 dimethylaminoethanol
2-dimethylaminoethanol
N-dimethylaminoethanol
N,N-dimethylaminoethanol
beta-dimethylaminoethyl alcohol
 dimethylethanolamine
N,N-dimethylethanolamine
 dimethylmonoethanolamine
 DMAE
 ethanol, 2-(dimethylamino)-
(2-hydroxyethyl)dimethylamine
N-(2-hydroxyethyl)dimethylamine
 kalpur P
 liparon
 propamine A
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