EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

N,N-dimethyl acetamide
ethanoic acid N,N-dimethylamide

Supplier Sponsors

Name:N,N-dimethylacetamide
CAS Number: 127-19-5Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:204-826-4
FDA UNII: JCV5VDB3HY
Nikkaji Web:J2.517H
Beilstein Number:1737614
MDL:MFCD00008686
XlogP3:-0.80 (est)
Molecular Weight:87.12193000
Formula:C4 H9 N O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:pharmaceuticals / chemical synthisis
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:colorless to pale yellow clear liquid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.93700 @ 25.00 °C.
Melting Point: -18.59 °C. @ 760.00 mm Hg (est)
Boiling Point: 165.00 °C. @ 760.00 mm Hg
Vapor Pressure:1.800000 mmHg @ 25.00 °C. (est)
Vapor Density:3.01 ( Air = 1 )
Flash Point: 158.00 °F. TCC ( 70.00 °C. )
logP (o/w): -0.770
Soluble in:
 water, 1.00E+06 mg/L @ 25 °C (exp)
 water, 5.747e+005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BASF
N,N-Dimethylacetamide
BOC Sciences
For experimental / research use only.
DMA
Charkit Chemical
DIMETHYLACETAMIDE
Eastman Chemical
Dimethylacetamide
EMD Millipore
For experimental / research use only.
N,N-Dimethylacetamide
Glentham Life Sciences
N,N-Dimethylacetamide, 99.5%
Indenta Group
Dimethyl Acetamide
Indis NV
For experimental / research use only.
N,N-Dimethylacetamide
Santa Cruz Biotechnology
For experimental / research use only.
N,N-Dimethylacetamide
Sigma-Aldrich
For experimental / research use only.
N,N-Dimethylacetamide analytical standard
Taminco (Eastman)
dimethylacetamide
TCI AMERICA
For experimental / research use only.
N,N-Dimethylacetamide >99.0%(GC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-chicken LDLo 12000 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 1242, 1970.

intraperitoneal-mouse LD50 2800 mg/kg
Yokohama Igaku. Yokohama Medicine. Vol. 31, Pg. 327, 1980.

intravenous-mouse LD50 3020 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976.

oral-mouse LD50 4620 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976.

intravenous-rabbit LDLo 8340 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 20, Pg. 1242, 1970.

intraperitoneal-rat LD50 2750 mg/kg
Journal of Reproduction and Fertility. Vol. 4, Pg. 219, 1962.

intravenous-rat LD50 2640 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 1581, 1976.

oral-rat LD50 4300 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(6), Pg. 76, 1980.

unreported-rat LD50 3000 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 19, Pg. 1073, 1969.

Dermal Toxicity:
skin-mouse LD50 9600 mg/kg
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LIVER: OTHER CHANGES BEHAVIORAL: FOOD INTAKE (ANIMAL)
Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. Vol. 13, Pg. 29, 1979.

skin-rabbit LD50 2240 mg/kg
SKIN AND APPENDAGES (SKIN): PRIMARY IRRITATION: AFTER TOPICAL EXPOSURE
American Industrial Hygiene Association Journal. Vol. 23, Pg. 95, 1962.

skin-rat LD50 > 2000 mg/kg
United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. Vol. 8EHQ-1190-0981

Inhalation Toxicity:
inhalation-mammal (species unspecified) LCLo 406 ppm
LIVER: FATTY LIVER DEGERATION
Toxicology and Applied Pharmacology. Vol. 3, Pg. 12, 1961.

inhalation-mouse LC50 7200 mg/m3
LIVER: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: ATAXIA
Zhonghua Yufangyixue Zazhi. Chinese Journal of Preventive Medicine. Vol. 13, Pg. 29, 1979.

inhalation-rat LC50 2475 ppm/1H
Drug and Chemical Toxicology. Vol. 9, Pg. 147, 1986.

 
Safety in Use Information:
Category:
pharmaceuticals / chemical synthisis
Recommendation for N,N-dimethyl acetamide usage levels up to:
 not for fragrance use.
 
Recommendation for N,N-dimethyl acetamide flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NIOSH International Chemical Safety Cards:search
NIOSH Pocket Guide:search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA Substance Registry Services (TSCA):127-19-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :31374
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
N,N-dimethylacetamide
Chemidplus:0000127195
EPA/NOAA CAMEO:hazardous materials
RTECS:127-19-5
 
References:
 N,N-dimethylacetamide
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:127-19-5
Pubchem (cid):31374
Pubchem (sid):134973907
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C20339
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2924.19.1150
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
Formulations/Preparations:
grades: high purity certified.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 zygopetalum crinitum
Search Trop Picture
 
Synonyms:
 acetamide, dimethyl-
 acetamide, N,N-dimethyl-
 acetamide, N,N-dimethyl- (8CI 9CI)
 acetdimethylamide
 acetic acid dimethylamide
 acetic acid N,N-dimethylamide
 acetic acid, dimethylamide
 acetyldimethylamine
N,N-dimethyl-acetamide
 dimethylacetamide
N,N-dimethylacetamide
N,N'-dimethylacetamide
 dimethylacetone amide
 dimethylamide acetate
N,N-dimethylethanamide
 DMAc
 ethanoic acid N,N-dimethylamide
 
 
Notes:
None found
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