minocycline hydrochloride hydrate
2-naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, monohydrochloride, (4S-(4a,4aa,5aa,12aa))-

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  BOC Sciences

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  Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
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  CODE126131 CODE126131
  Product(s):
  13614-98-7 Minocycline hydrochloride >98% by HPLC
  A salt prepared from minocycline; the preferred formulation for pharmaceutical applications; shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.

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  Glentham Life Sciences Ltd

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  CODE126131 CODE126131
  Product(s):
  GA7395 Minocycline hydrochloride

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  Penta International Corporation

  Chemistry innovation
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  For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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  CODE126131 CODE126131
  Product(s):
  13-80150 MINOCYCLINE HYDROCHLORIDE USP

Name: (4S,4aS,5aR,12aR)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride CAS Number: 13614-98-7 3D/inchi Other(deleted CASRN): 1071702-75-4 ECHA EINECS - REACH Pre-Reg: 237-099-7 FDA UNII: 0020414E5U MDL: MFCD00083669 Molecular Weight: 493.94356000 Formula: C23 H28 Cl N3 O7 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:pharmaceuticals / chemical synthisis   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   Physical Properties: Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Boiling Point: 659.40 °C. @ 760.00 mm Hg (est) Flash Point: 667.00 °F. TCC ( 352.60 °C. ) (est) logP (o/w): 0.808 (est)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: None found   Suppliers: BOC Sciences For experimental / research use only. Minocycline hydrochloride >98% by HPLC Odor: characteristic Use: A salt prepared from minocycline; the preferred formulation for pharmaceutical applications; shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis. Glentham Life Sciences Minocycline hydrochloride Penta International MINOCYCLINE HYDROCHLORIDE USP Santa Cruz Biotechnology For experimental / research use only. Minocycline, Hydrochloride ≥98% Sigma-Aldrich: Sigma For experimental / research use only. Minocycline hydrochloride crystalline sds   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: oral-human TDLo 14286 ug/kg/10 LUNGS, THORAX, OR RESPIRATION: RESPIRATORY OBSTRUCTION LUNGS, THORAX, OR RESPIRATION: DYSPNEA SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Archives of Internal Medicine. Vol. 154, Pg. 1633, 1994. intravenous-man TDLo 2857 ug/kg LUNGS, THORAX, OR RESPIRATION: "FIBROSIS, FOCAL (PNEUMOCONIOSIS)" LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Internal Medicine. Vol. 33, Pg. 177, 1994. oral-man TDLo 11429 ug/kg/4D SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Archives of Dermatology. Vol. 123, Pg. 18, 1987. oral-man TDLo 3893 mg/kg/4Y- SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Archives of Dermatology. Vol. 122, Pg. 17, 1986. intraperitoneal-mouse LD50 299 mg/kg Drugs in Japan Vol. 6, Pg. 811, 1982. intravenous-mouse LD50 154 mg/kg Drugs in Japan Vol. 6, Pg. 811, 1982. oral-mouse LD50 3600 mg/kg Drugs in Japan Vol. 6, Pg. 811, 1982. parenteral-mouse LDLo 620 mg/kg Chemotherapy Vol. 24, Pg. 17, 1978. intraperitoneal-rat LD50 331 mg/kg Drugs in Japan Vol. 6, Pg. 811, 1982. intravenous-rat LD50 164 mg/kg Drugs in Japan Vol. 6, Pg. 811, 1982. oral-rat LD50 2380 mg/kg Drugs in Japan Vol. 6, Pg. 811, 1982. Dermal Toxicity: subcutaneous-mouse LD50 2290 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 21, Pg. 319, 1990. subcutaneous-rat LD50 1700 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 21, Pg. 319, 1990. Inhalation Toxicity: Not determined   Safety in Use Information: Category: pharmaceuticals / chemical synthisis Recommendation for minocycline hydrochloride hydrate usage levels up to:   not for fragrance use.   Recommendation for minocycline hydrochloride hydrate flavor usage levels up to:   not for flavor use.   Safety References: ClinicalTrials.gov:search Daily Med:search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :54685925 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 (4S,4aS,5aR,12aR)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride Chemidplus:0011006272 RTECS:QI7630500 for cas# 13614-98-7   References:   (4S,4aS,5aR,12aR)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride NIST Chemistry WebBook: Search Inchi Pubchem (cid): 54685925 Pubchem (sid): 135175389   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements CHEMBL: View KEGG (GenomeNet): D00850 HMDB (The Human Metabolome Database): Search Export Tariff Code: 2941.30.0000 MedlinePlusSupp: View ChemSpider: View Wikipedia: View Formulations/Preparations: •...minocycline hydrochloride, usp (minocin, vectrin)...is avail in wide variety of forms for oral, topical & parenteral admin. •some of the tetracyclines are...marketed as flavored powders, ophthalmic soln & ointments, soln for injection, sol salts for prepn of oral suspensions & drops, & syrups & elixirs for pediatric use. tetracyclines   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   not found in nature   Synonyms:   arestin (4S,4aS,5aR,12aR)-4,7-bis( dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide;hydrochloride 4,7-bis( dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide monohydrochloride (4S-(4a,4aa,5aa,12aa))-4,7-bis( dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacene-2-carboxamide monohydrochloride   minocin   minocycline chloride   minocycline hydrochloride   minomax   minomycin   mynocine hydrochloride 2- naphthacenecarboxamide, 4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, monohydrochloride, (4S-(4a,4aa,5aa,12aa))-   tri-mino   vectrin   Articles:   None found yet. 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Notes: a tetracycline analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant staphylococcus infections.