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mimosine
1(4H)-pyridinepropanoic acid, alpha-amino-3-hydroxy-4-oxo-, (alphaS)-

Supplier Sponsors

Name:(2S)-2-amino-3-(3-hydroxy-4-oxopyridin-1-yl)propanoic acid
CAS Number: 500-44-7Picture of molecule3D/inchi
Other(deleted CASRN):27678-82-6
ECHA EINECS - REACH Pre-Reg:207-905-1
FDA UNII: Z46B1LUI5N
Nikkaji Web:J9.396C
MDL:MFCD00075909
XlogP3-AA:-3.50 (est)
Molecular Weight:198.17850000
Formula:C8 H10 N2 O4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 225.00 to 226.00 °C. @ 760.00 mm Hg
Boiling Point: 428.60 °C. @ 760.00 mm Hg (est)
Flash Point: 415.00 °F. TCC ( 213.00 °C. ) (est)
logP (o/w): -1.080 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Mimosine 98%
BOC Sciences
For experimental / research use only.
L-Mimosine >98%
Odor: characteristic
Use: L-Mimosine is a non-protein amino acid, and acts as an iron chelator.It is a toxic non-protein free amino acid otherwise chemically similar to tyrosine.
ExtraSynthese
For experimental / research use only.
L-Mimosine
Penta International
L-MIMOSINE
Santa Cruz Biotechnology
For experimental / research use only.
L-Mimosine ≥98%
Sigma-Aldrich: Sigma
For experimental / research use only.
L-Mimosine from Koa hoale seeds ≥98%
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for mimosine usage levels up to:
 not for fragrance use.
 
Recommendation for mimosine flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :440473
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(2S)-2-amino-3-(3-hydroxy-4-oxopyridin-1-yl)propanoic acid
Chemidplus:0000500447
RTECS:UT7610000 for cas# 500-44-7
 
References:
 (2S)-2-amino-3-(3-hydroxy-4-oxopyridin-1-yl)propanoic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):440473
Pubchem (sid):134978156
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C04771
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2933.39.4700
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 leucena glauca seed
Search Trop Picture
 
Synonyms:
(2S)-2-amino-3-(3-hydroxy-4-oxopyridin-1-yl)propanoic acid
(S)-alpha-amino-3-hydroxy-4-oxo-1(4H)-pyridylpropionic acid
 leucaenine
 leucena glauca alpha-amino acid
 leucenol
 mimosin
1(4H)-pyridinepropanoic acid, alpha-amino-3-hydroxy-4-oxo-, (alphaS)-
 

Articles:

PubMed:Non-protein amino acids in Australian acacia seed: Implications for food security and recommended processing methods to reduce djenkolic acid.
PubMed:Endothelin-converting enzyme is a plausible target gene for hypoxia-inducible factor.
PubMed:Antioxidant and tyrosinase inhibitory activities of flavonoids from Trifolium nigrescens Subsp. petrisavi.
PubMed:Antioxidant activity and inhibitory effects of lead (Leucaena leucocephala) seed extracts against lipid oxidation in model systems.
PubMed:Feeding potential of cassava (Manihot esculenta Crantz) peels ensiled with Leucaena leucocephala and Gliricidia sepium assessed with West African dwarf goats.
PubMed:Solid-phase synthesis of mimosine tetrapeptides and their inhibitory activities on neuraminidase and tyrosinase.
PubMed:Curcumin provides potential protection against the activation of hypoxia and prolyl 4-hydroxylase inhibitors on prostate-specific antigen expression in human prostate carcinoma cells.
PubMed:Inhibition of melanosis formation in Pacific white shrimp by the extract of lead (Leucaena leucocephala) seed.
PubMed:Inhibitory effect of mimosine on polyphenoloxidase from cephalothoraxes of Pacific white shrimp (Litopenaeus vannamei).
PubMed:Coat condition of ringtailed lemurs, Lemur catta, at Berenty Reserve, Madagascar: II. Coat and tail alopecia associated with Leucaena leucocepahala, 2001-2006.
PubMed:Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling.
PubMed:Do calcium-mediated cellular signalling pathways, prostaglandin E2 (PGE2), estrogen or progesterone receptor antagonists, or bacterial endotoxins affect bovine placental function in vitro?
PubMed:Potential therapeutic applications of some antinutritional plant secondary metabolites.
PubMed:Partial purification, characterization, and histochemical localization of fully latent desert truffle (Terfezia claveryi Chatin) polyphenol oxidase.
PubMed:Enhancement of beta-glucosidase and beta-galactosidase of Trigonella foenum-graecum by exposure to the allelochemical mimosine.
PubMed:Nutritional and economic benefits of Leucaena and Gliricidia as feed supplements for small ruminants in humid West Africa.
PubMed:Mimosine degradation in calves fed a sole diet of Leucaena leucocephala in India.
PubMed:An automated colorimetric method for mimosine in Leucaena leaves.
PubMed:Determination of mimosine in soybean sauce.
 
Notes:
None found
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