manganese powder, 7439-96-5

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CAS Number:	7439-96-5	3D/inchi
Other(deleted CASRN):	17375-02-9
ECHA EINECS - REACH Pre-Reg:	231-105-1
FDA UNII:	42Z2K6ZL8P
Nikkaji Web:	J89.952F
MDL:	MFCD00011111
Molecular Weight:	54.93804500
Formula:	Mn
BioActivity Summary:	listing
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:special dietary and nutritional additives

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
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Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search
FDA Mainterm (IAUFC):	7439-96-5 ; MANGANESE

Physical Properties:

Appearance:	silvery powder (est)
Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Melting Point:	1246.00 °C. @ 760.00 mm Hg (est)
Boiling Point:	2061.00 °C. @ 760.00 mm Hg (est)
Flash Point:	32.00 °F. TCC ( 0.00 °C. ) (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

American Elements

Manganese Powder

Santa Cruz Biotechnology

For experimental / research use only.

Manganese Powder

Sigma-Aldrich: Aldrich

For experimental / research use only.

Manganese powder, ≥99.9% trace metals basis

sds

Strem Chemicals

For experimental / research use only.

Manganese powder (99.5%)

Safety Information:

Preferred SDS: View

Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 9000 mg/kg "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972Vol. -, Pg. 21, 1972.
Dermal Toxicity:
Not determined
Inhalation Toxicity:
inhalation-man TCLo 2300 ug/m3 BRAIN AND COVERINGS: OTHER DEGENERATIVE CHANGES BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) BEHAVIORAL: MUSCLE WEAKNESS American Industrial Hygiene Association Journal. Vol. 27, Pg. 454, 1966.

Safety in Use Information:

Category:
special dietary and nutritional additives
Recommendation for manganese powder usage levels up to:
	not for fragrance use.

Recommendation for manganese powder flavor usage levels up to:
	not for flavor use.

Safety References:

European Food Safety Authority (EFSA) reference(s):

Scientific opinion on the safety and efficacy of manganese compounds (E5) as feed additives for all species: manganous oxide and manganous sulphate monohydrate, based on a dossier submitted by Eramet & Comilog Chemicals S.A.
View page or View pdf

Outcome of a public consultation on the Draft Scientific Opinion of the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) on Dietary Reference Values for manganese
View page or View pdf

Scientific Opinion on Dietary Reference Values for manganese
View page or View pdf

EPI System: View

EPA-Iris:IRIS

ClinicalTrials.gov:search

Daily Med:search

NIOSH International Chemical Safety Cards:search

NIOSH Pocket Guide:search

Chemical Carcinogenesis Research Information System:Search

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA Substance Registry Services (TSCA):7439-96-5

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :23930

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:nwg

manganese

Chemidplus:0007439965

EPA/NOAA CAMEO:hazardous materials

RTECS:7439-96-5

References:

	manganese
NIST Chemistry WebBook:	Search Inchi
Canada Domestic Sub. List:	7439-96-5
Pubchem (cid):	23930
Pubchem (sid):	134988330

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:	View
CHEBI:	View
KEGG (GenomeNet):	C00034
HMDB (The Human Metabolome Database):	HMDB01333
FooDB:	FDB003636
YMDB (Yeast Metabolome Database):	YMDB01521
Export Tariff Code:	8111.00.4500
FDA Listing of Food Additive Status:	View
MedlinePlusSupp:	View
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View
Wikipedia:	View
Formulations/Preparations: grades: technical, pure or electrolytic, powdered.

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

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Synonyms:

manganese

Articles:

PubMed:Substituted 2,2'-bipyridines by nickel-catalysis: 4,4'-di-tert-butyl-2,2'-bipyridine.

PubMed:Hexa-kis-(dimethyl-formamide-κO)manganese(II) (dimethyl-formamide-κO)pentakis(-thio-cyanato--κN)chromate(III).

PubMed:Hexa-kis-(dimethyl-formamide-κO)manganese(II) μ-oxido-bis-[trichlorido-ferrate(III)].

PubMed:Bis{μ(2)-2-[(2-hy-droxy-eth-yl)(meth-yl)amino]-ethano-lato}bis-(μ(3)-N-methyl-2,2'-aza-nediyldiethano-lato)tetra-kis-(thio-cyan-atato-κN)dichromium(III)dimanganese(II) dimethyl-formamide tetra-solvate.

PubMed:Preparation of functionalized organomanganese(II) reagents by direct insertion of manganese to aromatic and benzylic halides.

PubMed:Bis(tetra-phenyl-phospho-nium) tetra-iodidomanganate(II) acetone monosolvate.

PubMed:Intraarticular carcinogenesis bioassays of CoCrMo and TiAlV alloys in rats.

PubMed:Tumorigenic effect of an organomanganese compound on F344 rats and Swiss albino mice.

Notes:

a trace element with atomic symbol mn, atomic number 25, and atomic weight 54.94. it is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (from ama drug evaluations annual 1992, p2035) Manganese is a chemical element, designated by the symbol Mn. It has the atomic number 25. Manganese(II) ions function as cofactors for a number of enzymes in higher organisms, where they are essential in detoxification of superoxide free radicals. The element is a required trace mineral for all known living organisms. [Wikipedia]

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