EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

magnesium sulfate heptahydrate
sulfuric acid, magnesium salt (1:1), heptahydrate

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Name:magnesium sulfate heptahydrate
CAS Number: 10034-99-8Picture of molecule3D/inchi
FDA UNII:SK47B8698T
MDL:MFCD00149785
Molecular Weight:246.47278000
Formula:H14 Mg O11 S
NMR Predictor:Predict (works with chrome or firefox)
Category:flavor enhancers, nutrient supplements
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
184.1443 Magnesium sulfate View - review
JECFA Food Additive: Magnesium Sulfate
GSFA Codex: Magnesium sulfate (518)
FDA Mainterm (SATF):10034-99-8 ; MAGNESIUM SULFATE
FDA Regulation:
FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1443 Magnesium sulfate.
 
Physical Properties:
Appearance:white crystalline powder (est)
Food Chemicals Codex Listed: No
Specific Gravity:1.67000 @ 25.00 °C.
Boiling Point: 330.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.000034 mmHg @ 25.00 °C. (est)
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -1.031 (est)
Soluble in:
 water
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Allan Chemical
Magnesium Sulfate 7H2O
American Elements
Magnesium Sulfate Heptahydrate 99%
Odor: characteristic
Use: Magnesium Sulfate Heptahydrate is a moderately water and acid soluble Magnesium source for uses compatible with sulfates. Sulfate compounds are salts or esters of sulfuric acid formed by replacing one or both of the hydrogens with a metal. Most metal sulfate compounds are readily soluble in water for uses such as water treatment, unlike fluorides and oxides which tend to be insoluble. Organometallic forms are soluble in organic solutions and sometimes in both aqueous and organic solutions. Metallic ions can also be dispersed utilizing suspended or coated nanoparticles (See also application discussion at Nanotechnology Information and at Quantum Dots) and deposited utilizing sputtering targets and evaporation materials for uses such as solar energy materials and fuel cells. Magnesium Sulfate Heptahydrate is generally immediately available in most volumes. Ultra high purity, high purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
Magnesium Sulfate Heptahydrate FCC
Bristol Botanicals
Epsom salts
Charkit Chemical
MAGNESIUM SULFATE DIHYDRATE
Covalent Chemical
Magnesium Sulphate (Anhy/hepta)
ECSA Chemicals
MAGNESIUM SULFATE HEPTAHYDRATE USP
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
ECSA Chemicals
MAGNESIUM SULPHATE FCC HEPTAHYDRATE
ECSA Chemicals
MAGNESIUM SULPHATE RPE-ACS-FOR ANALYSIS-REAG
ECSA Chemicals
MAGNESIUM SULPHATE RPH- PH.EUR.-FU-BP-DAB,
ECSA Chemicals
MAGNESIUM SULPHATE RPH- PH.EUR.-FU-BP-DAB,
ECSA Chemicals
MAGNESIUM SULPHATE TECN.
Glentham Life Sciences
Magnesium sulfate heptahydrate
Global Calcium
Magnesium Sulfate USP
Global Calcium
Magnesium Sulphate Heptahydrate EP/BP
Global Calcium
Magnesium Sulphate IP
Jost Chemical
Magnesium Sulfate Heptahydrate USP Granular
Sigma-Aldrich
For experimental / research use only.
Magnesium sulfate heptahydrate ACS reagent, ≥98%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-man TDLo 183 mg/kg/4H-I
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Journal of Toxicology, Clinical Toxicology. Vol. 20, Pg. 107, 1983.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavor enhancers, nutrient supplements
Recommendation for magnesium sulfate heptahydrate usage levels up to:
 not for fragrance use.
 
 
Safety References:
ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :24843
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
magnesium sulfate heptahydrate
Chemidplus:0010034998
RTECS:OM4508000 for cas# 10034-99-8
 
References:
 magnesium sulfate heptahydrate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):24843
Pubchem (sid):134990631
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEBI:View
KEGG (GenomeNet):C12505
HMDB (The Human Metabolome Database):Search
FooDB:FDB015432
Export Tariff Code:2833.21.0000
FDA Listing of Food Additive Status:View
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 epsom salts
 magnesium sulfate (1:1) heptahydrate
 magnesium sulfate heptahydrate (MgSO4.7H2O)
 magnesium sulfate hydrate (1:1:7)
 magnesium sulphate heptahydrate
 magnesium(II) sulfate heptahydrate
 magnesium(II), sulfate, heptahydrate
 sulfuric acid magnesium salt (1:1), heptahydrate
 sulfuric acid, magnesium salt (1:1), heptahydrate
 sulfuric acid, magnesium salt, heptahydrate
 

Articles:

PubMed:Effects of Short-term Feeding Magnesium before Slaughter on Blood Metabolites and Postmortem Muscle Traits of Halothane-carrier Pigs.
PubMed:A preliminary comparison of three dermal exposure sampling methods: rinses, wipes and cotton gloves.
PubMed:Magnesium sulphate at 30 to 34 weeks' gestational age: neuroprotection trial (MAGENTA)--study protocol.
PubMed:Properties of liquids and dusts: how do they influence dermal loading during immersion, deposition, and surface contact exposure pathways?
PubMed:Bath salt intoxication causing acute kidney injury requiring hemodialysis.
PubMed:Fatal manganese intoxication due to an error in the elaboration of Epsom salts for a liver cleansing diet.
PubMed:Severe hypermagnesemia after enteral administration of Epsom salts.
PubMed:Useless perinatal therapies.
PubMed:Deliberate overdose with Epsom salts.
PubMed:Timing of magnesium supplementation administered through drinking water to improve fresh and stored pork quality.
PubMed:Reflections on errors in neonatology: II. The "Heroic" years, 1950 to 1970.
PubMed:The impact of longissimus glycolytic potential and short-term feeding of magnesium sulfate heptahydrate prior to slaughter on carcass characteristics and pork quality.
PubMed:Magnesium sulfate after transient hypoxia-ischemia fails to prevent delayed cerebral energy failure in the newborn piglet.
PubMed:Non-ideality of aqueous solutions of polyethylene glycol: consequences for its use as a macromolecular crystallizing agent in vapor-diffusion experiments.
PubMed:Prophylactic effects of intravenous magnesium on hypertensive emergencies after cataract surgery. A new contribution to the pharmacological use of magnesium in anaesthesiology.
PubMed:Time courses of equilibration for ammonium sulfate, sodium chloride and magnesium sulfate heptahydrate in the Z/3 crystallization plate.
PubMed:Hypermagnesemia-induced paralytic ileus.
PubMed:Simple medium that preserves low concentrations of Escherichia coli for use in the water bacteriology proficiency test.
PubMed:Severe failure to thrive and diarrhoea caused by laxative abuse.
PubMed:Doctor Nehemiah Grew (1641-1712) and the Epsom salts.
PubMed:[Preparation of patients in diagnostic contrast radiography of the urinary and bile tracts and the large intestine].
PubMed:Epsom salts and coronary heart disease.
PubMed:Epsom-salts poisoning and a review of magnesium-ion physiology.
PubMed:EPSOM SALTS FOR HYALINE-MEMBRANE DISEASE.
PubMed:EPSOM SALTS FOR HYALINE-MEMBRANE DISEASE.
PubMed:EPSOM SALTS AND NUTRIENT VALUE OF BERRIES.
PubMed:[Obtaining both Glauber's and Epsom salts from astrakhanite].
PubMed:The use of Epsom salts, historically considered.
PubMed:Two Ounces of Potassae Nitras Taken in Mistake for Epsom Salts.
 
Notes:
a small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. it causes direct inhibition of action potentials in myometrial muscle cells. excitation and contraction are uncoupled, which decreases the frequency and force of contractions. (from ama drug evaluations annual, 1992, p1083) Used in foods as a flavour enhancer, nutrient supplement and processing aid
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