levamisole hydrochloride
imidazo[2,1-b]thiazole, 2,3,5,6-tetrahydro-6-phenyl-, (6S)-, hydrochloride (1:1)

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  Product(s):
  16595-80-5 Levamisole Hydrochloride 98%

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  GA3670 Levamisol hydrochloride

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  CT1215 Levamisole Hydrochloride >99.0%(T)
  SDS

CAS Number: 16595-80-5 3D/inchi Other(deleted CASRN): 24593-45-1 ECHA EINECS - REACH Pre-Reg: 240-654-6 FDA UNII: DL9055K809 MDL: MFCD00012675 Molecular Weight: 240.75561000 Formula: C11 H13 Cl N2 S BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:pharmaceuticals / chemical synthisis   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   Physical Properties: Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Boiling Point: 344.40 °C. @ 760.00 mm Hg (est) Vapor Pressure: 0.000066 mmHg @ 25.00 °C. (est) Flash Point: 324.00 °F. TCC ( 162.10 °C. ) (est) logP (o/w): 1.845 (est) Soluble in:   water, 1116 mg/L @ 25 °C (est)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: None found   Suppliers: BOC Sciences For experimental / research use only. Levamisole Hydrochloride 98% Glentham Life Sciences Levamisol hydrochloride Santa Cruz Biotechnology For experimental / research use only. Levamisole Hydrochloride ≥99% Sigma-Aldrich: Sigma For experimental / research use only. (-)-Tetramisole hydrochloride ≥99% (GC) sds TCI AMERICA For experimental / research use only. Levamisole Hydrochloride >99.0%(T) sds   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: parenteral-frog LD50 363 mg/kg Archives Internationales de Pharmacodynamie et de Therapie. Vol. 289, Pg. 278, 1987. intramuscular-mouse LD50 121 mg/kg Fortschritte der Medizin. Vol. 94, Pg. 793, 1976. intraperitoneal-mouse LD50 34 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: TREMOR Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 3141, 1982. intravenous-mouse LD50 18 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: TREMOR Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 3141, 1982. oral-mouse LD50 223 mg/kg LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: TREMOR Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 3141, 1982. intraperitoneal-rat LD50 42 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: TREMOR LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 3141, 1982. intravenous-rat LD50 26 mg/kg BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 3141, 1982. oral-rat LD50 180 mg/kg Archives of Toxicology. Vol. 54, Pg. 275, 1983. Dermal Toxicity: subcutaneous-mouse LD50 52 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: TREMOR Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 3141, 1982. subcutaneous-rat LD50 80 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: TREMOR Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 10, Pg. 3141, 1982. Inhalation Toxicity: Not determined   Safety in Use Information: Category: pharmaceuticals / chemical synthisis Recommendation for levamisole hydrochloride usage levels up to:   not for fragrance use.   Recommendation for levamisole hydrochloride flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View ClinicalTrials.gov:search Daily Med:search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :27944 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;hydrochloride Chemidplus:0016595805 RTECS:NJ5960000 for cas# 16595-80-5   References:   (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;hydrochloride NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 16595-80-5 Pubchem (cid): 27944 Pubchem (sid): 134991423   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements CHEBI: View CHEMBL: View KEGG (GenomeNet): C07906 HMDB (The Human Metabolome Database): Search Export Tariff Code: 2909.30.6000 ChemSpider: View Wikipedia: View   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   not found in nature   Synonyms:   imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (-)- (8CI)   imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, (S)-   imidazo(2,1-b)thiazole, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, L-(-)-   imidazo[2,1-b]thiazole, 2,3,5,6-tetrahydro-6-phenyl-, (6S)-, hydrochloride (1:1)   lecamisole HCl   levamisol hydrochloride   levomysol hydrochloride   nilverm   niratic hydrochloride   niratic-puron hydrochloride (6S)-6- phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole hydrochloride (6S)-6- phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole hydrochloride (1:1) 6- phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole hydrochloride (1:1) (6S)-6- phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;hydrochloride (6S)-6- phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazolhydrochlorid (S)-(-)-6- phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride (S)-6- phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride L-(-)-2,3,5,6- tetrahydro-6-phenyl-imidazo(2,1-b)thiazole hydrochloride (-)-2,3,5,6- tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride (-)-2,3,5,6- tetrahydro-6-phenylimidazo[2,1-b]thiazole monohydrochloride L-(-)-2,3,5,6- tetrahydro-6-phenylimidazo[2,1-b]thiazole Monohydrochloride   tetramisole hydrochloride (-)- tetramisole hydrochloride L- tetramisole hydrochloride   Articles:   None found yet. 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Notes: an antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemotaxis and t-lymphocyte function. paradoxically, this immune enhancement appears to be beneficial in rheumatoid arthritis where dermatitis, leukopenia, and thrombocytopenia, and nausea and vomiting have been reported as side effects. (from smith and reynard, textbook of pharmacology, 1991, p435-6)