lactobionic acid
 
Notes:
a component of erythromycin lactobionate and university of wisconsin-lactobionate solution.
  • American International Chemical, LLC.
    • American International Chemical, Inc.
      Consistent sources
      North American supplier for globally sourced ingredients.
      AIC is a Framingham, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of 30 Sales Representatives, along with our 19 strategically located warehouses are ready to supply product when and where you need it.
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      Product(s):
      LBAGIP Lactobionic Acid
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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      Product(s):
      12-07400 LACTOBIONIC ACID POWDER
       
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(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoic acid (Click)
CAS Number: 96-82-2Picture of molecule
ECHA EINECS - REACH Pre-Reg: 202-538-3
FDA UNII: 65R938S4DV
Nikkaji Web: J4.724D
Beilstein Number: 95054
MDL: MFCD00078147
XlogP3-AA: -5.00 (est)
Molecular Weight: 358.29774000
Formula: C12 H22 O12
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: buffering agents
 
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 864.68 °C. @ 760.00 mm Hg (est)
Flash Point: 606.00 °F. TCC ( 319.10 °C. ) (est)
logP (o/w): -3.848 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: buffering agents
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Suppliers:
American International Chemical, LLC.
Lactobionic Acid
BOC Sciences
For experimental / research use only.
Lactobionic acid
Carbosynth
For experimental / research use only.
Lactobionic acid
ExtraSynthese
For experimental / research use only.
Lactobionic Acid
Global Calcium
Lactobionic Acid EP/BP
Global Calcium
Lactobionic Acid
Penta International
LACTOBIONIC ACID POWDER
Santa Cruz Biotechnology
For experimental / research use only.
Lactobionic Acid ≥97%
Sigma-Aldrich: Aldrich
For experimental / research use only.
Lactobionic Acid 97%
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: buffering agents
Recommendation for lactobionic acid usage levels up to:
 not for fragrance use.
 
Recommendation for lactobionic acid flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 7314
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoic acid
Chemidplus: 0000096822
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References:
 (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoic acid
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 7314
Pubchem (sid): 134972693
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
Golm Metabolome Database: Search
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2932.90.5000
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
4-(b-D-dalactosido)-D-gluconic acid
4-O-b-D-galactopyranosyl-D-gluconic acid
4-O-beta-d-galactopyranosyl-dextro-gluconic acid
D-gluconic acid, 4-O-b-D-galactopyranosyl-
 lactobionicacid
(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoic acid
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Articles:
PubMed: Synthesis, biocompatible, and self-assembly properties of poly (ethylene glycol)/lactobionic acid-grafted chitosan.
PubMed: Lactobionic acid coupled liposomes: an innovative strategy for targeting hepatocellular carcinoma.
PubMed: Lactobionic Acid-modified dendrimer-entrapped gold nanoparticles for targeted computed tomography imaging of human hepatocellular carcinoma.
PubMed: Targeting liver cancer via ASGP receptor using 5-FU-loaded surface-modified PLGA nanoparticles.
PubMed: Glyco-nanoparticles with sheddable saccharide shells: a unique and potent platform for hepatoma-targeting delivery of anticancer drugs.
PubMed: Polyvinylamine-G-galactose is a route to bioactivated silica surfaces.
PubMed: The liver-targeting study of the N-galactosylated chitosan in vivo and in vitro.
PubMed: Aqueous solubility of calcium L-lactate, calcium D-gluconate, and calcium D-lactobionate: importance of complex formation for solubility increase by hydroxycarboxylate mixtures.
PubMed: Cellular behaviour of hepatocyte-like cells from nude mouse bone marrow-derived mesenchymal stem cells on galactosylated poly(D,L-lactic-co-glycolic acid).
PubMed: Targeting Mantle Cell Lymphoma with Anti-SYK Nanoparticles.
PubMed: Equilibrium surface tension, dynamic surface tension, and micellization properties of lactobionamide-type sugar-based gemini surfactants.
PubMed: Bio-production of lactobionic acid: current status, applications and future prospects.
PubMed: Hepatocyte-targeting gene transfer mediated by galactosylated poly(ethylene glycol)-graft-polyethylenimine derivative.
PubMed: Feeding strategies for enhanced lactobionic acid production from whey by Pseudomonas taetrolens.
PubMed: Selection method of pH conditions to establish Pseudomonas taetrolens physiological states and lactobionic acid production.
PubMed: Cell-specific intracellular anticancer drug delivery from mesoporous silica nanoparticles with pH sensitivity.
PubMed: Hydrotropic polymeric mixed micelles based on functional hyperbranched polyglycerol copolymers as hepatoma-targeting drug delivery system.
PubMed: Production of organic acids by periplasmic enzymes present in free and immobilized cells of Zymomonas mobilis.
PubMed: Hepatocyte-targeted delivery using ph-sensitive liposomes loaded with lactosylnorcantharidin phospholipid complex: preparation, characterization, and therapeutic evaluation in vivo and in vitro.
PubMed: Physiological heterogeneity of Pseudomonas taetrolens during lactobionic acid production.
PubMed: Lactobionic acid as antioxidant and moisturizing active in alkyl polyglucoside-based topical emulsions: the colloidal structure, stability and efficacy evaluation.
PubMed: Galactosylated nanostructured lipid carriers for delivery of 5-FU to hepatocellular carcinoma.
PubMed: Optimization of lactobionic acid production by Acetobacter orientalis isolated from Caucasian fermented milk, "Caspian Sea yogurt".
PubMed: Role of dissolved oxygen availability on lactobionic acid production from whey by Pseudomonas taetrolens.
PubMed: Application of lactobionic acid and nonionic surfactants as solubilizing agents for parenteral formulation of clarithromycin.
PubMed: Does lactobionic acid affect the colloidal structure and skin moisturizing potential of the alkyl polyglucoside-based emulsion systems?
PubMed: Production of lactobionic acid and sorbitol from lactose/fructose substrate using GFOR/GL enzymes from Zymomonas mobilis cells: a kinetic study.
PubMed: Design and synthesis of dual-ligand modified chitosan as a liver targeting vector.
PubMed: Metabolomic analysis of the toxic effects of chronic exposure to low-level dichlorvos on rats using ultra-performance liquid chromatography-mass spectrometry.
PubMed: Efficient lactobionic acid production from whey by Pseudomonas taetrolens under pH-shift conditions.
PubMed: Evaluation of clarithromycin lactobionate as a novel chiral selector for enantiomeric separation of basic drugs in capillary electrophoresis.
PubMed: Development of a successive targeting liposome with multi-ligand for efficient targeting gene delivery.
PubMed: Self-assembled virus-like particles from rotavirus structural protein VP6 for targeted drug delivery.
PubMed: Analysis of experimental errors in bioprocesses. 1. Production of lactobionic acid and sorbitol using the GFOR (glucose-fructose oxidoreductase) enzyme from permeabilized cells of Zymomonas mobilis.
PubMed: Mesoporous silica nanoparticles end-capped with collagen: redox-responsive nanoreservoirs for targeted drug delivery.
PubMed: Fabrication of lactobionic-loaded chitosan microcapsules as potential drug carriers targeting the liver.
PubMed: Galactosyl conjugated N-succinyl-chitosan-graft-polyethylenimine for targeting gene transfer.
PubMed: Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model.
PubMed: Fluorine-18 labeled galactosylated chitosan for asialoglycoprotein-receptor-mediated hepatocyte imaging.
PubMed: Development and in vitro characterization of galactosylated low molecular weight chitosan nanoparticles bearing doxorubicin.
PubMed: Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid.
PubMed: Galactosylated poly(2-(2-aminoethyoxy)ethoxy)phosphazene/DNA complex nanoparticles: in vitro and in vivo evaluation for gene delivery.
PubMed: Galactosylated solid lipid nanoparticles with cucurbitacin B improves the liver targetability.
PubMed: Porphyrin and galactosyl conjugated micelles for targeting photodynamic therapy.
PubMed: Self-assembly and characterization of Pluronic P105 micelles for liver-targeted delivery of silybin.
PubMed: Superparamagnetic iron oxide nanoparticles as a dual imaging probe for targeting hepatocytes in vivo.
PubMed: Acute acidification of stratum corneum membrane domains using polyhydroxyl acids improves lipid processing and inhibits degradation of corneodesmosomes.
PubMed: Galactosylated LDL nanoparticles: a novel targeting delivery system to deliver antigen to macrophages and enhance antigen specific T cell responses.
PubMed: Effect of culture medium composition on Trichoderma reesei's morphology and cellulase production.
PubMed: Amphiphilic perfluoroalkyl carbohydrates as new tools for liver imaging.
PubMed: Immobilization of lactobionic acid on the surface of cadmium sulfide nanoparticles and their interaction with hepatocytes.
PubMed: Maintenance of an acidic stratum corneum prevents emergence of murine atopic dermatitis.
PubMed: Involvement of Acetobacter orientalis in the production of lactobionic acid in Caucasian yogurt ("Caspian Sea yogurt") in Japan.
PubMed: Galactosylated fluorescent labeled micelles as a liver targeting drug carrier.
PubMed: Kinetic modeling of a bi-enzymatic system for efficient conversion of lactose to lactobionic acid.
PubMed: Green oxidation of renewable carbohydrates: lactobionic acid production as an example.
PubMed: Lactose enhances cellulase production by the filamentous fungus Acremonium cellulolyticus.
PubMed: Bubble-free oxygenation of a bi-enzymatic system: effect on biocatalyst stability.
PubMed: Production of lactose-free galacto-oligosaccharide mixtures: comparison of two cellobiose dehydrogenases for the selective oxidation of lactose to lactobionic acid.
PubMed: Purification and characterization of a carbohydrate: acceptor oxidoreductase from Paraconiothyrium sp. that produces lactobionic acid efficiently.
PubMed: Inherent toxicity of organ preservation solutions to cultured hepatocytes.
PubMed: Organic-inorganic mesoporous nanocarriers integrated with biogenic ligands.
PubMed: Characterization of the bga1-encoded glycoside hydrolase family 35 beta-galactosidase of Hypocrea jecorina with galacto-beta-D-galactanase activity.
PubMed: [Galactosylated derivatives of low-molecular-weight chitosan: production and properties].
PubMed: Synthesis of a novel glycoconjugated chitosan and preparation of its derived nanoparticles for targeting HepG2 cells.
PubMed: Quantification of lactobionic acid and sorbitol from enzymatic reaction of fructose and lactose by high-performance liquid chromatography.
PubMed: Identification of live liver cancer cells in a mixed cell system using galactose-conjugated fluorescent nanoparticles.
PubMed: Oxidation of lactose to lactobionic acid by a Microdochium nivale carbohydrate oxidase: kinetics and operational stability.
PubMed: Scale-up of enzymatic production of lactobionic acid using the rotary jet head system.
PubMed: Enzymatically oxidized lactose and derivatives thereof as potential protein cross-linkers.
PubMed: Surface modification of magnetite nanoparticles using lactobionic acid and their interaction with hepatocytes.
PubMed: Dynamic seeding and perfusion culture of hepatocytes with galactosylated vegetable sponge in packed-bed bioreactor.
PubMed: Tetranuclear copper(II) complexes bridged by alpha-D-glucose-1-phosphate and incorporation of sugar acids through the Cu4 core structural changes.
PubMed: Asialoglycoprotein-receptor-targeted hepatocyte imaging using 99mTc galactosylated chitosan.
PubMed: Uronic acids functionalized polyethyleneimine (PEI)-polyethyleneglycol (PEG)-graft-copolymers as novel synthetic gene carriers.
PubMed: Sugar-based gemini surfactants with peptide bonds-synthesis, adsorption, micellization, and biodegradability.
PubMed: Oxidation of lactose with bromine.
PubMed: Synergistic effect of poly(ethylenimine) on the transfection efficiency of galactosylated chitosan/DNA complexes.
PubMed: Morphology and metabolism of Ba-alginate encapsulated hepatocytes with galactosylated poly(allyl amine) and poly(vinyl alcohol) as extracellular matrices.
PubMed: Hepatocyte-targeted nuclear imaging using 99mTc-galactosylated chitosan: conjugation, targeting, and biodistribution.
PubMed: Polynorbornene polycationic polymers as gene transfer agents. Influence of the counterion for in vitro transfection.
PubMed: Wide nanoscopic pore of maxi-anion channel suits its function as an ATP-conductive pathway.
PubMed: Toxicological studies on Lactose Oxidase from Microdochium nivale expressed in Fusarium venenatum.
PubMed: Lactose derivatives are inhibitors of Trypanosoma cruzi trans-sialidase activity toward conventional substrates in vitro and in vivo.
PubMed: Co-culture of hepatocytes and fibroblasts by micropatterned immobilization of beta-galactose derivatives.
PubMed: Galactosylated chitosan/DNA nanoparticles prepared using water-soluble chitosan as a gene carrier.
PubMed: The use of polyhydroxy acids (PHAs) in photoaged skin.
PubMed: Kinetics and mechanism of the reduction of CrVI and CrV by D-lactobionic acid.
PubMed: Evaluation of a galactose-carrying gelatin sponge for hepatocytes culture and transplantation.
PubMed: Morphology and metabolism of Ba-alginate-encapsulated hepatocytes with galactosylated chitosan and poly(vinyl alcohol) as extracellular matrices.
PubMed: Oxygen solubilities of media used in electrochemical respiration measurements.
PubMed: Development of polymeric nanoparticulate drug delivery systems: evaluation of nanoparticles based on biotinylated poly(ethylene glycol) with sugar moiety.
PubMed: Galactosylated low molecular weight chitosan as DNA carrier for hepatocyte-targeting.
PubMed: Development of a polymeric nanoparticulate drug delivery system. In vitro characterization of nanoparticles based on sugar-containing conjugates.
PubMed: Preparation of alginate/galactosylated chitosan scaffold for hepatocyte attachment.
PubMed: Anionic polysaccharides. A class of substances with hepatoprotective and antiadhesive properties in rat liver preservation.
PubMed: Galactosylated chitosan-graft-poly(ethylene glycol) as hepatocyte-targeting DNA carrier.
PubMed: Synthesis and Surface Properties of N-Alkyl-N-methylgluconamides and N-Alkyl-N-methyllactobionamides.
PubMed: Hexose oxidase from Chondrus crispus: improved purification using perfusion chromatography(*).
PubMed: [Preparation, X-ray structural and spectroscopic studies of some D-lactobionic acid complexes with Cs(I), Fe(III) and di-n-butyltin(IV)].
PubMed: Performances of new sugar-bearing poly(acrylamide) copolymers as DNA sieving matrices and capillary coatings for electrophoresis.
PubMed: Protective effects of lactobionate in modified phosphate-buffered sucrose.
PubMed: Evaluation of several saccharides as osmotic agent for peritoneal dialysate.
PubMed: Self-assembled hydrogel nanoparticles from curdlan derivatives: characterization, anti-cancer drug release and interaction with a hepatoma cell line (HepG2).
PubMed: Inhibitory effect of erythromycin on P-glycoprotein-mediated biliary excretion of doxorubicin in rats.
PubMed: Galactosylated chitosan-graft-dextran as hepatocyte-targeting DNA carrier.
PubMed: The stimulation of antral motility by erythromycin is attenuated by hyperglycemia.
PubMed: Glutathione, lactobionate, and histidine: cryptic inhibitors of matrix metalloproteinases contained in University of Wisconsin and histidine/tryptophan/ketoglutarate liver preservation solutions.
PubMed: Spontaneous Vesicle Formation by Helical Glycopeptides in Water.
PubMed: Amino acid residues of heparin cofactor II required for stimulation of thrombin inhibition by sulphated polyanions.
PubMed: The effect of lactose derivatives on intestinal lactic acid bacteria.
PubMed: Doxorubicin physical state in solution and inside liposomes loaded via a pH gradient.
PubMed: Effect of inline filtration on ViaSpan cold-storage solution.
PubMed: In vitro effects of aprosulate sodium, a novel anticoagulant, on platelet activation: possible mechanism for antiplatelet action.
PubMed: Determination of raffinose and lactobionic acid in ViaSpan by anion exchange chromatography with pulsed amperometric detection.
PubMed: Synthesis of glycolipids containing disaccharides and two longer alkyl chains and their applications as enzyme modifiers.
PubMed: Effects of different cold preservation solutions on restoration of hepatic energy metabolism during cold reperfusion.
PubMed: Effects of cation interactions on sugar anion conformation in complexes of lactobionate and gluconate with calcium, sodium or potassium.
PubMed: Interaction between the sulfated lactobionic acid (LW 10082) and other antithrombotic agents in animal thrombosis model.
PubMed: Analysis of heparin-like pharmaceuticals by capillary zone electrophoresis and isotachophoresis.
PubMed: Cardioplegic protection of hearts with pre-arrest ischaemic injury: effect of glucose, aspartate, and lactobionate.
PubMed: Synthesis of model glycolipids having two long alkyl chains.
PubMed: Effects of calcium concentration, lactobionate content, and sodium/ potassium ratio of preservation solutions on resting left ventricular pressure and postreperfusion function of rabbit heterotopic heart transplants.
PubMed: Inhibition of hydroxyl radical production by lactobionate, adenine, and tempol.
PubMed: Sulfated polysaccharide anticoagulants suppress natural killer cell activity in vitro.
PubMed: In vivo comparative study of two lactobionate based solutions for prolonged heart preservation.
PubMed: Restoration of hepatic metabolism by cold reperfusion.
PubMed: Organ preservation.
PubMed: An underlying mechanism for improved liver preservation with a combined histidine-lactobionate-raffinose flush solution.
PubMed: High-performance capillary electrophoresis of O-glycosidically linked sialic acid-containing oligosaccharides in glycoproteins as their alditol derivatives with low-wavelength UV monitoring.
PubMed: Current trends in the development of anticoagulant and antithrombotic drugs.
PubMed: Reduced production of the deleterious hydroxyl free radical during the final reperfusion of isolated rabbit heart with the use of an improved sodium lactobionate-based cardioplegic medium.
PubMed: Rapid assessment of islet cell viability by MTT assay after cold storage in different solutions.
PubMed: Improvements in human islet purification by inclusion of a colloid in cold storage solutions.
PubMed: Rinse solution containing a protease inhibitor and Na-lactobionate increases graft survival after rat pancreas preservation.
PubMed: Protamine sulfate neutralization of the anticoagulant activity of Aprosulate, a synthetic sulfated lactobionic acid amide.
PubMed: The in vitro influence of sulfated bis-lactobionic acid amides on O6-alkylguanine-DNA alkyltransferase, DNase I, nucleic acid synthesis and chromatin structure.
PubMed: A prospective randomized clinical trial of liver preservation using high-sodium versus high-potassium lactobionate/raffinose solution.
PubMed: [Addition of an osmotic agent to liver preservative solutions in a model of in vitro preservation of hepatocytes].
PubMed: Heart-lung protection from ischemic injury during 8 hour hypothermic preservation.
PubMed: Carbon tetrachloride-induced cell death in perfused livers from phenobarbital-pretreated rats under hypoxic conditions and various ionic milieu. Further evidence for calcium-dependent irreversible changes.
PubMed: 31P NMR studies of rat liver cold preservation with histidine-buffered lactobionate solution.
PubMed: Efficacy of lactobionate-enriched cardioplegic solution in preserving compliance of cold-stored heart transplants.
PubMed: A lactobionate-based extracellular-type solution for donor heart preservation.
PubMed: Molecular weight profiling of low molecular weight heparins utilizing a heparinase degraded oligosaccharide mixture as a calibrator.
PubMed: Production of novel oligosaccharide oxidase by wheat bran solid-state fermentation.
PubMed: Lactobionic and gluconic acid complexes of FeII and FeIII; control of oxidation pathways by an organ transplantation preservant.
PubMed: Antithrombin III- and heparin cofactor II-mediated anticoagulant and antiprotease actions of heparin and its synthetic analogues.
PubMed: An examination of the effects of solutions containing histidine and lactobionate for heart, pancreas, and liver preservation in the rat.
PubMed: Determination of the association constant of monovalent mode protein-sugar interaction by capillary zone electrophoresis.
PubMed: A comparison of some simplified lactobionate preservation solutions with standard UW solution and Eurocollins solution for pancreas preservation.
PubMed: Calcium antagonists in sodium lactobionate sucrose solution for rat liver preservation.
PubMed: Inhibition of factor X, factor V and prothrombin activation by the bis(lactobionic acid amide) LW10082.
PubMed: A comparison of histadine lactobionate solution with University of Wisconsin solution for rat liver and heart preservation.
PubMed: Prolonged rat pancreas preservation using a solution with the combination of histidine and lactobionate.
PubMed: Influence of hypersulfated lactobionic acid amides on tissue plasminogen activator release.
PubMed: The need for glutathione and allopurinol in HL solution for rat liver preservation.
PubMed: Successful 20-hour rat liver preservation with chlorpromazine in sodium lactobionate sucrose solution.
PubMed: Interaction of the sulfated lactobionic acid amide LW 10082 with thrombin and its endogenous inhibitors.
PubMed: Influence of synthetic sulfated bis-lactobionic acid amides on tissue-type plasminogen activator release.
PubMed: A comparison of a new solution combining histidine and lactobionate with UW solution and eurocollins for rat liver preservation.
PubMed: Pharmacologic profile of the antithrombotic and bleeding actions of sulfated lactobionic acid amides.
PubMed: Influence of lactobionic acid on the kinetics of thrombin in human plasma.
PubMed: Protamine sulfate neutralization of lactobionic acid amides.
PubMed: Pharmacodynamics of a sulfated lactobionic acid amide-derived antithrombotic agent (Aprosulate) in primates.
PubMed: Modulation of the enzymatic activity of alpha-thrombin by polyanions: consequences on intrinsic activation of factor V and factor VIII.
PubMed: [Effect of subcutaneous administration of lactobionic acid on coagulation and platelet function].
PubMed: Biochemical studies on sulfated lactobionic acid amides.
PubMed: University of Wisconsin solution without lactobionate and raffinose. Protection of metabolism in cold-stored kidneys.
PubMed: Lactobionate as the most important component in UW solution for liver preservation.
PubMed: Examination of the role of the impermeants lactobionate and raffinose in a modified UW solution.
PubMed: The effect of bismuth on the selective oxidation of lactose on supported palladium catalysts.
PubMed: Purification and properties of two lactose hydrolases from Trichosporon cutaneum.
PubMed: Analysis of UW solution in a rat liver transplant model.
PubMed: Important components of the UW solution.
PubMed: Anticoagulant and antithrombotic properties of synthetic sulfated bis-lactobionic acid amides.
PubMed: Hypothermic perfusion of rabbit livers: effect of perfusate composition (Ca and lactobionate) on enzyme release and tissue swelling.
PubMed: The response of liver to lactobionate/raffinose (University of Wisconsin--UW) solution during hypothermic preservation: a study using 31phosphorus nuclear magnetic resonance.
PubMed: Lactobionic acid as an iron chelator: a rationale for its effectiveness as an organ preservant.
PubMed: Successful 72-hour cold storage of dog kidneys with UW solution.
PubMed: Partial purification and characterization of Naegleria fowleri beta-glucosidase.
PubMed: Studies on monovalent anaphylactogens with carbohydrate auxiliary groups: exclusion of an artefact.
PubMed: Lactose inhibits the growth of Rhizobium meliloti cells that contain an actively expressed Escherichia coli lactose operon.
PubMed: Regulation of lactose-phosphoenolpyruvate-dependent phosphotransferase system and beta-D-phosphogalactoside galactohydrolase activities in Lactobacillus casei.
PubMed: Bioavailability of iron- and copper-supplemented milk for Mexican school children.
PubMed: Inhibition of ischemic induced cellular swelling in kidney cortex tissue by lactobionate anions.
PubMed: Distinct galactose phosphoenolpyruvate-dependent phosphotransferase system in Streptococcus lactis.
PubMed: Changes in the substrate specificities of an enzyme during directed evolution of new functions.
PubMed: Physiological studies of beta-galactosidase induction in Kluyveromyces lactis.
PubMed: The metabolism of carbohydrates by extremely halophilic bacteria: the identification of lactobionic acid as a product of lactose metabolism by Halobacterium saccharovorum.
PubMed: Enzymic formation of lactobionic acid from lactose.
PubMed: Evidence for the formation and utilization of lactobionic acid by Penicillium chrysogenum.
PubMed: [Oxidation of lactose in lactobionic acid by pathogenic or saprophytic bacteria (Bacterium anitratum)].
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