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laevo-pipecolinic acid
(S)-piperidine-2-carboxylic acid

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CAS Number: 3105-95-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:221-462-1
FDA UNII: 69374CKB33
Nikkaji Web:J215.717I
Beilstein Number:81093
XlogP3:-2.30 (est)
Molecular Weight:129.15907000
Formula:C6 H11 N O2
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 7.406e+004 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
Alfa Biotechnology
For experimental / research use only.
L(-)-Pipecolinic acid 98%
BOC Sciences
For experimental / research use only.
L-Pipecolinic Acid ≥98%, ≥95%e.e.
Changzhou Longo Chemical
L-Pipecolic Acid
Glentham Life Sciences
L-Pipecolic acid
Sigma-Aldrich: Sigma
For experimental / research use only.
L-Pipecolinic Acid 99% (titration)
For experimental / research use only.
L-Pipecolinic Acid >98.0%(T)
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
natural substances and extractives
Recommendation for laevo-pipecolinic acid usage levels up to:
 not for fragrance use.
Recommendation for laevo-pipecolinic acid flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :439227
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(2S)-piperidine-2-carboxylic acid
 (2S)-piperidine-2-carboxylic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):439227
Pubchem (cas):3105-95-1
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
Golm Metabolome Database:Search
Metabolomics Database:Search
KEGG (GenomeNet):C00408
HMDB (The Human Metabolome Database):HMDB00716
Export Tariff Code:2933.39.4700
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
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 pipecolic acid, (-)-
L-pipecolinic acid
(2S)-piperidine-2-carboxylic acid
(S)-piperidine-2-carboxylic acid
2-piperidinecarboxylic acid, (S)- (9CI)


PubMed:Xylapeptide A, an Antibacterial Cyclopentapeptide with an Uncommon L-Pipecolinic Acid Moiety from the Associated Fungus Xylaria sp. (GDG-102).
PubMed:Regio- and stereoselective oxygenation of proline derivatives by using microbial 2-oxoglutarate-dependent dioxygenases.
PubMed:Identification and characterization of 2-oxoglutarate-dependent dioxygenases catalyzing selective cis-hydroxylation of proline and pipecolinic acid from actinomycetes.
PubMed:L-Pipecolinic acid derived Lewis base organocatalyst for asymmetric reduction of N-aryl imines by trichlorosilane: effects of the side amide group on catalytic performances.
PubMed:A water-soluble calix[4]resorcinarene with L-pipecolinic acid groups as a chiral NMR solvating agent.
PubMed:Synthesis of function-oriented 2-phenyl-2H-chromene derivatives using L-pipecolinic acid and substituted guanidine organocatalysts.
PubMed:Evolution of chiral Lewis basic N-formamide as highly effective organocatalyst for asymmetric reduction of both ketones and ketimines with an unprecedented substrate scope.
PubMed:Sequencing and analysis of the biosynthetic gene cluster of the lipopeptide antibiotic Friulimicin in Actinoplanes friuliensis.
PubMed:A highly enantioselective lewis basic organocatalyst for reduction of N-aryl imines with unprecedented substrate spectrum.
PubMed:Petrosifungins A and B, novel cyclodepsipeptides from a sponge-derived strain of Penicillium brevicompactum.
PubMed:Synthesis and structure-activity relationships of gelatinase inhibitors derived from matlystatins.
PubMed:The isolation of L-pipecolinic acid from Trifolium repens.
PubMed:Naturally occurring L-pipecolinic acid.
Present in beans and other legumes, and in lesser quantities in other plants including barley, hops, malt and mushrooms
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