EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

laevo-(+)-glutamic acid hydrochloride
L-glutamic acid, hydrochloride (1:1)

Supplier Sponsors

Name:(2S)-2-aminopentanedioic acid hydrochloride
CAS Number: 138-15-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:205-315-9
FDA UNII:M0C2SP444T
Beilstein Number:3565569
MDL:MFCD00012619
Molecular Weight:183.59050000
Formula:C5 H10 Cl N O4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:special dietary and nutritional additives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
182.1047 L-Glutamic acid hydrochloride View-review
FDA Mainterm: GLUTAMIC ACID HYDROCHLORIDE
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart D--Special Dietary and Nutritional Additives
Sec. 172.320 Amino acids.


FDA PART 182 -- SUBSTANCES GENERALLY RECOGNIZED AS SAFE
Subpart B--Multiple Purpose GRAS Food Substances
Sec. 182.1047 Glutamic acid hydrochloride.
 
Physical Properties:
Appearance:white powder (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 214.00 °C. @ 760.00 mm Hg
Boiling Point: 333.80 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.000025 mm/Hg @ 25.00 °C. (est)
Flash Point: 312.00 °F. TCC ( 155.70 °C. ) (est)
logP (o/w): -1.435 (est)
Soluble in:
 water, 380000 mg/L @ 20 °C (exp)
 
Organoleptic Properties:
Odor Strength:none
Odor Description:at 100.00 %. odorless
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Aceto
L-Glutamic Acid HCl
BOC Sciences
For experimental / research use only.
L-(+)-Glutamic acid hydroChloride PURIFIED
Charkit Chemical
GLUTAMIC ACID HCL, L-
EMD Millipore
For experimental / research use only.
L-Glutamic Acid Hydrochloride
Glentham Life Sciences
L-Glutamic acid hydrochloride
Penta International
L-GLUTAMIC ACID HYDROCHLORIDE NATURAL, Kosher
Penta International
L-GLUTAMIC ACID HYDROCHLORIDE, Kosher
Sigma-Aldrich: Sigma
For experimental / research use only.
L-Glutamic Acid Hydrochloride ≥99% (TLC)
TCI AMERICA
For experimental / research use only.
L-Glutamic Acid Hydrochloride >98.0%(T)
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
Xi - Irritant
R 41 - Risk of serious damage to eyes.
S 02 - Keep out of the reach of children.
S 22 - Do not breath dust.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: special dietary and nutritional additives
Recommendation for laevo-(+)-glutamic acid hydrochloride usage levels up to:
 not for fragrance use.
 
Recommendation for laevo-(+)-glutamic acid hydrochloride flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
NLM Hazardous Substances Data Bank:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):138-15-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :2723891
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(2S)-2-aminopentanedioic acid hydrochloride
Chemidplus:0000138158
 
References:
 (2S)-2-aminopentanedioic acid hydrochloride
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:138-15-8
Pubchem (cid):2723891
Pubchem (sid):134973917
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
CHEMBL:View
KEGG (GenomeNet):D07539
HMDB (The Human Metabolome Database):Search
FooDB:FDB012534
Export Tariff Code:2922.42.5000
FDA Listing of Food Additive Status:View
ChemSpider:View
Formulations/Preparations:
•capsules, nf, 340 mg. •it is available in capsule form which under some circumstances is more convenient than diluted hydrochloric acid. ...glutamic acid hydrochloride, nf, capsules, nf, 300 mg. •available commercially as the naturally-occurring l(+)-enantiomer in the form of the free base or hydrochloride salt. l-glutamic acid
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 acidothyn
L-2-aminoglutaric acid hydrochloride
(2S)-2-aminopentanedioic acid hydrochloride
S(+)-1-aminopropane-1,3-dicarboxylic acid hydrochloride
 gastuloric
L-glutamic acid HCl
L-glutamic acid hydrochloride
L-(+)-glutamic acid hydrochloride
L-glutamic acid hydrochloride (1:1)
L-glutamic acid monohydrochloride
L-glutamic acid, hydrochloride
L-glutamic acid, hydrochloride (1:1)
 glutamic acid, hydrochloride, L-
L-(+)-glutamicacidhydrochloride
 

Articles:

PubMed:History of glutamate production.
PubMed:The detection properties of ammonia SAW gas sensors based on L-glutamic acid hydrochloride.
PubMed:Absence of effect of glutamic acid hydrochloride on the bioavailability of oral ganciclovir in AIDS patients with cytomegalovirus disease.
PubMed:N-acetyl-L-glutamic acid.
PubMed:In vivo interaction of ketoconazole and sucralfate in healthy volunteers.
PubMed:In vitro analysis of the interaction between sucralfate and ketoconazole.
PubMed:pH-related changes in the absorption of dipyridamole in the elderly.
PubMed:Modification of gastric pH with oral glutamic acid hydrochloride.
PubMed:Effect of food and gastric acidity on absorption of orally administered ketoconazole.
PubMed:[Separation of amino acids contained in the mother liquor of glutamic acid hydrochloride].
PubMed:Clinical effect of combined mephenesin and glutamic acid hydrochloride in the menopausal and postmenopausal patient.
PubMed:The use of glutamic acid hydrochloride for nausea and vomiting of pregnancy.
 
Notes:
a non-essential amino acid naturally occurring in the l-form. glutamic acid is the most common excitatory neurotransmitter in the central nervous system. Dietary supplement, nutrient, flavouring agent and enhancer
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