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itaconic acid
butanedioic acid, 2-methylene-

Supplier Sponsors

Name:2-methylidenebutanedioic acid
CAS Number: 97-65-4Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:202-599-6
FDA UNII: Q4516562YH
Nikkaji Web:J38.149G
Beilstein Number:1759501
XlogP3-AA:-0.10 (est)
Molecular Weight:130.09962000
Formula:C5 H6 O4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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DG SANTE Food Contact Materials:itaconic acid
FDA Mainterm (IAUFC):97-65-4 ; ITACONIC ACID
Physical Properties:
Appearance:white crystals (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:1.57300 @ 25.00 °C.
Melting Point: 162.00 to 164.00 °C. @ 760.00 mm Hg
Melting Point: 172.00 °C. @ 760.00 mm Hg
Boiling Point: 268.00 °C. @ 760.00 mm Hg
Boiling Point: 381.00 to 382.00 °C. @ 760.00 mm Hg (est)
Flash Point: 390.00 °F. TCC ( 198.70 °C. ) (est)
logP (o/w): -0.075 (est)
Soluble in:
 water, 7.68E+04 mg/L @ 20 °C (exp)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
For experimental / research use only.
Itaconic Acid
BOC Sciences
For experimental / research use only.
2-methylenesuccinic acid Purity >98%
Covalent Chemical
Itaconic Acid
Glentham Life Sciences
Itaconic acid
Sigma-Aldrich: Aldrich
For experimental / research use only.
Itaconic Acid ≥99%
Silver Fern Chemical
Itaconic Acid
Odor: characteristic
Use: It is primarily used as a co-monomer in the production of styrene-butadiene-acrylonitrile and acrylate latexes with applications in the paper, resins, plastics, oil, and architectural coating industry.
SysKem Chemie
Itaconic Acid
For experimental / research use only.
Itaconic Acid >99.0%(T)
Zhong Ya Chemical
Itaconic Acid Tech Grade
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
natural substances and extractives
Recommendation for itaconic acid usage levels up to:
 not for fragrance use.
Recommendation for itaconic acid flavor usage levels up to:
 not for flavor use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Report of EFSA on the risk assessment of salts of authorised acids, phenols or alcohols for use in food contact materials [1]
View page or View pdf

EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):97-65-4
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :811
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
2-methylidenebutanedioic acid
 2-methylidenebutanedioic acid
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:97-65-4
Pubchem (cid):811
Pubchem (sid):134970642
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
Golm Metabolome Database:Search
Metabolomics Database:Search
KEGG (GenomeNet):C00490
HMDB (The Human Metabolome Database):HMDB02092
YMDB (Yeast Metabolome Database):YMDB00716
Export Tariff Code:2917.19.7050
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 found in nature
 butanedioic acid, 2-methylene-
 methylene butane dioic acid
 methylene succinic acid
 methylenebutanedioic acid
2-methylenebutanedioic acid
 methylenesuccinic acid
2-methylenesuccinic acid
2-methylidenebutanedioic acid
2-propene-1,2-dicarboxylic acid
 propylene dicarboxylic acid
 succinic acid, methylene- (8CI)


PubMed:Production of itaconic acid using metabolically engineered Escherichia coli.
PubMed:Metabolic engineering of itaconate production in Escherichia coli.
PubMed:Tailored Thiol-Functional Polyamides: Synthesis and Functionalization.
PubMed:Influence of the pH on the itaconic acid production with Aspergillus terreus.
PubMed:Systemic responses of BALB/c mice to salmonella typhimurium infection.
PubMed:Synthesis and evaluation of iron-doped titania/silane based hydrogel for the adsorptional photocatalytic degradation of Victoria blue under visible light.
PubMed:Improving itaconic acid production through genetic engineering of an industrial Aspergillus terreus strain.
PubMed:Direct production of itaconic acid from liquefied corn starch by genetically engineered Aspergillus terreus.
PubMed:Early pregnancy metabolite profiling discovers a potential biomarker for the subsequent development of gestational diabetes mellitus.
PubMed:Synthesis of bio-based methacrylic acid by decarboxylation of itaconic acid and citric acid catalyzed by solid transition-metal catalysts.
PubMed:Pathway transfer in fungi: Transporters are the key to success.
PubMed:Enzymatic hydrolysis of beech wood lignocellulose at high solid contents and its utilization as substrate for the production of biobutanol and dicarboxylic acids.
PubMed:Metabolic engineering of Saccharomyces cerevisiae for itaconic acid production.
PubMed:Stimuli-sensitive hydrogel based on N-isopropylacrylamide and itaconic acid for entrapment and controlled release of candida rugosa lipase under mild conditions.
PubMed:Evaluation of the effects of nanoscale zero-valent iron (nZVI) dispersants on intrinsic biodegradation of trichloroethylene (TCE).
PubMed:A novel star-shaped poly(carboxylic acid) for resin-modified glass-ionomer restoratives.
PubMed:pH-Responsive poly(itaconic acid-co-N-vinylpyrrolidone) hydrogels with reduced ionic strength loading solutions offer improved oral delivery potential for high isoelectric point-exhibiting therapeutic proteins.
PubMed:Assessment of the drug loading, in vitro and in vivo release behavior of novel pH-sensitive hydrogel.
PubMed:Metabolism: pathogens love the poison.
PubMed:Filamentous fungi in microtiter plates-an easy way to optimize itaconic acid production with Aspergillus terreus.
PubMed:Preparation and characteristics of sodium alginate/Na(+)rectorite-g-itaconic acid/acrylamide hydrogel films.
PubMed:Synthesis of poly(alkenoic acid) with L-leucine residue and methacrylate photopolymerizable groups useful in formulating dental restorative materials.
PubMed:Catalyzed ester synthesis using Candida rugosa lipase entrapped by poly(N-isopropylacrylamide-co-itaconic acid) hydrogel.
PubMed:Preparation and evaluation of a novel star-shaped polyacid-constructed dental glass-ionomer system.
PubMed:Bacterial itaconate degradation promotes pathogenicity.
PubMed:The preparation of magnetic molecularly imprinted nanoparticles for the recognition of bovine hemoglobin.
PubMed:Development of molecularly imprinted polymer in porous film format for binding of phenol and alkylphenols from water.
PubMed:Expression of the Aspergillus terreus itaconic acid biosynthesis cluster in Aspergillus niger.
PubMed:[Progress in engineering Escherichia coli for production of high-value added organic acids and alcohols].
PubMed:Soap-free emulsion polymerization of poly (methyl methacrylate-co-butyl acrylate): effects of anionic comonomers and methanol on the different characteristics of the latexes.
PubMed:Synthesis, characterization, and acute oral toxicity evaluation of pH-sensitive hydrogel based on MPEG, poly(ε-caprolactone), and itaconic acid.
PubMed:Cysteine is the general base that serves in catalysis by isocitrate lyase and in mechanism-based inhibition by 3-nitropropionate.
PubMed:Optimization of a yeast RNA interference system for controlling gene expression and enabling rapid metabolic engineering.
PubMed:Cloning, characterization and application of a glyceraldehyde-3-phosphate dehydrogenase promoter from Aspergillus terreus.
PubMed:A systems biology approach for the identification of target genes for the improvement of itaconic acid production in Aspergillus species.
PubMed:Precision synthesis of bio-based acrylic thermoplastic elastomer by RAFT polymerization of itaconic acid derivatives.
PubMed:Homo-Roche ester derivatives by asymmetric hydrogenation and organocatalysis.
PubMed:Relationship between morphology and itaconic acid production by Aspergillus terreus.
PubMed:Synthesis and properties of a bio-based epoxy resin with high epoxy value and low viscosity.
PubMed:Overexpression of a modified 6-phosphofructo-1-kinase results in an increased itaconic acid productivity in Aspergillus niger.
PubMed:Poly(itaconic acid)-grafted chitosan adsorbents with different cross-linking for Pb(II) and Cd(II) uptake.
PubMed:Properties of a proline-containing glass ionomer dental cement.
PubMed:Isocitric acid production from rapeseed oil by Yarrowia lipolytica yeast.
PubMed:Synthesis and evaluation of chitosan-graft-poly (2-hydroxyethyl methacrylate-co-itaconic acid) as a drug carrier for controlled release of tramadol hydrochloride.
PubMed:Rational design and chromatographic evaluation of histamine imprinted polymers optimised for solid-phase extraction of wine samples.
PubMed:Application of scale-up criterion of constant oxygen mass transfer coefficient (kLa) for production of itaconic acid in a 50 L pilot-scale fermentor by fungal cells of Aspergillus terreus.
PubMed:Novel bioadhesive hyaluronan-itaconic acid crosslinked films for ocular therapy.
PubMed:Identification of an endo-1,4-beta-xylanase of Ustilago maydis.
PubMed:The combined influence of substrate elasticity and surface-grafted molecules on the ex vivo expansion of hematopoietic stem and progenitor cells.
PubMed:Facile one-step synthesis of monodisperse micron-sized latex particles with highly carboxylated surfaces.
PubMed:Bactericidal effect of poly(acrylamide/itaconic acid)-silver nanoparticles synthesized by gamma irradiation against Pseudomonas aeruginosa.
PubMed:Targeting enzymes to the right compartment: metabolic engineering for itaconic acid production by Aspergillus niger.
PubMed:Rational synthesis of pindolol imprinted polymer by non-covalent protocol based on computational approach.
PubMed:Genome-scale reconstruction and in silico analysis of Aspergillus terreus metabolism.
PubMed:Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.
PubMed:Continuous production and recovery of itaconic acid in a membrane bioreactor.
PubMed:Biochar of animal origin: a sustainable solution to the global problem of high-grade rock phosphate scarcity?
PubMed:Colorimetric test-systems for creatinine detection based on composite molecularly imprinted polymer membranes.
PubMed:4-(4-Iodo-anilino)-2-methyl-ene-4-oxo-butanoic acid.
PubMed:Dual-templates molecularly imprinted monolithic columns for the evaluation of serotonin and histamine in CEC.
PubMed:Biochemistry of microbial itaconic acid production.
PubMed:Reduced by-product formation and modified oxygen availability improve itaconic acid production in Aspergillus niger.
PubMed:Itaconic acid--a biotechnological process in change.
PubMed:Computational and experimental investigation of molecular imprinted polymers for selective extraction of dimethoate and its metabolite omethoate from olive oil.
PubMed:Particle shape optimization by changing from an isotropic to an anisotropic nanostructure: preparation of highly active and stable supported Pt catalysts in microemulsions.
PubMed:Rhodium-catalysed asymmetric hydrogenation as a valuable synthetic tool for the preparation of chiral drugs.
PubMed:Microbial Community-Level Physiological Profiles (CLPP) and herbicide mineralization potential in groundwater affected by agricultural land use.
PubMed:Animal bone char solubilization with itaconic acid produced by free and immobilized Aspergillus terreus grown on glycerol-based medium.
PubMed:Enhanced itaconic acid production in Aspergillus niger using genetic modification and medium optimization.
PubMed:Preliminary assessment of the safety evaluation of novel pH-sensitive hydrogel.
PubMed:Analysis and quantification of ammonia-oxidizing bacteria community with amoA gene in sewage treatment plants.
PubMed:Controlled release of lipase from Candida rugosa loaded into hydrogels of N-isopropylacrylamide and itaconic acid.
PubMed:Microbial production of itaconic acid: developing a stable platform for high product concentrations.
PubMed:Alkadienyl and alkenyl itaconic acids (ceriporic acids G and H) from the selective white-rot fungus Ceriporiopsis subvermispora: a new class of metabolites initiating ligninolytic lipid peroxidation.
PubMed:Six novel constitutive promoters for metabolic engineering of Aspergillus niger.
PubMed:Molecular imprinting solid phase extraction for selective detection of methidathion in olive oil.
PubMed:Resin zirconia bonding promotion with some novel coupling agents.
PubMed:Parallel synthesis of 2-substituted 6-(5-oxo-1-phenylpyrrolidin-3-yl)pyrimidine-5-carboxamides.
PubMed:Synthesis and characterization of thermo- and pH-sensitive poly(vinyl alcohol)/poly(N, N-diethylacrylamide-co-itaconic acid) semi-IPN hydrogels.
PubMed:Biomass pretreatment affects Ustilago maydis in producing itaconic acid.
PubMed:Removal of cyanotoxins from surface water resources using reusable molecularly imprinted polymer adsorbents.
PubMed:Diverse rare lipid-related metabolites including ω-7 and ω-9 alkenylitaconic acids (ceriporic acids) secreted by a selective white rot fungus, Ceriporiopsis subvermispora.
PubMed:Stitching phospholanes together piece by piece: new modular di- and tridentate stereodirecting ligands.
PubMed:Complexation of amidated pectin with poly(itaconic acid) as a polycarboxylic polymer model compound.
PubMed:Itaconic acid is a mammalian metabolite induced during macrophage activation.
PubMed:Epoxy ceriporic acid produced by selective lignin-degrading fungus Ceriporiopsis subvermispora.
PubMed:Selective homogeneous hydrogenation of biogenic carboxylic acids with [Ru(TriPhos)H]+: a mechanistic study.
PubMed:Functional copolymer/organo-MMT nanoarchitectures. VI. Synthesis and characterization of novel nanocomposites by interlamellar controlled/living radical copolymerization via preintercalated RAFT-agent/organoclay complexes.
PubMed:Ultrasonically set novel NVC-containing glass-ionomer cements for applications in restorative dentistry.
PubMed:Sorption of zinc by novel pH-sensitive hydrogels based on chitosan, itaconic acid and methacrylic acid.
PubMed:An insight into the mechanism of CEC separation of template analogues on a norepinephrine-imprinted monolith.
PubMed:Effects of N-vinylcaprolactam containing polyelectrolytes on hardness, fluoride release and water sorption of conventional glass ionomers.
PubMed:Itaconic acid derivatives and diketopiperazine from the marine-derived fungus Aspergillus aculeatus CRI322-03.
PubMed:Biobased poly(propylene sebacate) as shape memory polymer with tunable switching temperature for potential biomedical applications.
PubMed:Surface properties and bond strength measurements of N-vinylcaprolactam (NVC)-containing glass-ionomer cements.
PubMed:A clone-based transcriptomics approach for the identification of genes relevant for itaconic acid production in Aspergillus.
PubMed:Preparation and evaluation of a monolithic molecularly imprinted polymer for the chiral separation of neurotransmitters and their analogues by capillary electrochromatography.
PubMed:Synthesis and study of a molecularly imprinted polymer for the specific extraction of indole alkaloids from Catharanthus roseus extracts.
PubMed:Metal ion mediated molecularly imprinted polymer for selective capturing antibiotics containing beta-diketone structure.
PubMed:Metabolic engineering of Escherichia coli for biotechnological production of high-value organic acids and alcohols.
PubMed:Measure of microhardness, fracture toughness and flexural strength of N-vinylcaprolactam (NVC)-containing glass-ionomer dental cements.
PubMed:Gluconic acid production by Aspergillus terreus.
PubMed:Chemical profiling of lentil (Lens culinaris Medik.) Cultivars and isolation of compounds.
PubMed:Selective and flexible transformation of biomass-derived platform chemicals by a multifunctional catalytic system.
PubMed:Immobilization of laccase in kappa-carrageenan based semi-interpenetrating polymer networks.
PubMed:Enhancing itaconic acid production by Aspergillus terreus.
PubMed:Surface characterization of functionalized latexes with different surface functionalities using rheometry and dynamic light scattering.
PubMed:Influence of unsaturated carbonic acids on hemocompatibility and cytotoxicity of poly-vinylacetate based co-polymers.
PubMed:Acrylamide-sepiolite based composite hydrogels for immobilization of invertase.
PubMed:A novel monoclonal antibody specific to peptide pdnaelvlltlgqawqg.
PubMed:The derivatization of bioplatform molecules by using KF/alumina catalysis.
PubMed:One-pot synthesis of functionalized 4-oxo-2-thioxo-1,3-thiazinanes from primary amines, CS(2), and itaconic anhydride.
PubMed:Hydrogels of N-isopropylacrylamide copolymers with controlled release of a model protein.
PubMed:Enantioselective protonation of itaconimides with thiols and the rotational kinetics of the axially chiral C-N bond.
PubMed:Synthesis and properties of polycarboxylate-type green surfactants with S- or N-linkages.
PubMed:Catalytic (transfer) deuterogenation in D2O as deuterium source with H2 and HCO2H as electron sources.
PubMed:Biotechnological production of itaconic acid and its biosynthesis in Aspergillus terreus.
PubMed:Bonding effectiveness and interfacial characterization of a nano-filled resin-modified glass-ionomer.
PubMed:Swelling properties of copolymeric hydrogels of poly(ethylene glycol) monomethacrylate and monoesters of itaconic acid for use in drug delivery.
PubMed:Effects of N-vinylpyrrolidone (NVP) containing polyelectrolytes on surface properties of conventional glass-ionomer cements (GIC).
PubMed:Characterization of pH-responsive hydrogels of poly(itaconic acid-g-ethylene glycol) prepared by UV-initiated free radical polymerization as biomaterials for oral delivery of bioactive agents.
PubMed:Absolute configuration of ceriporic acids, the iron redox-silencing metabolites produced by a selective lignin-degrading fungus, Ceriporiopsis subvermispora.
PubMed:Synthesis and characterization of a novel N-vinylcaprolactam-containing acrylic acid terpolymer for applications in glass-ionomer dental cements.
PubMed:Synthesis of a proline-modified acrylic acid copolymer in supercritical CO2 for glass-ionomer dental cement applications.
PubMed:Three lanthanide complexes derived from itaconic acid and 2,2'-bipyridine.
PubMed:Imprinted polymers for chiral resolution of (+/-)-ephedrine. Part 3: NMR predictions and HPLC results with alternative functional monomers.
PubMed:Hydroxyapatite crystals biologically inspired on titanium by using an organic template based on the copolymer of acrylic acid and itaconic acid.
PubMed:Synthesis and application of novel multi-arm poly(carboxylic acid)s for glass-ionomer restoratives.
PubMed:Reaction between drug substances and pharmaceutical excipients: formation of citric acid esters and amides of carvedilol in the solid state.
PubMed:Property changes of powdery polyacrylonitrile synthesized by aqueous suspension polymerization during heat-treatment process under air atmosphere.
PubMed:De novo synthesis of (Z)- and (E)-7-hexadecenylitaconic acids by a selective lignin-degrading fungus, Ceriporiopsis subvermispora.
PubMed:Rational design and study on recognition property of paracetamol-imprinted polymer.
PubMed:Hemoglobin recognition of molecularly imprinted hydrogels prepared at different pHs.
PubMed:Synthesis and characterization of a novel fast-set proline-derivative-containing glass ionomer cement with enhanced mechanical properties.
PubMed:Cloning and functional characterization of the cis-aconitic acid decarboxylase (CAD) gene from Aspergillus terreus.
PubMed:Production of renewable polymers from crop plants.
PubMed:Modification of conventional glass-ionomer cements with N-vinylpyrrolidone containing polyacids, nano-hydroxy and fluoroapatite to improve mechanical properties.
PubMed:Synthesis of N-vinylpyrrolidone modified acrylic acid copolymer in supercritical fluids and its application in dental glass-ionomer cements.
PubMed:Use of itaconic acid-based polymers for solid-phase extraction of deoxynivalenol and application to pasta analysis.
PubMed:Fluconazole release from hydrogels including acrylamide-acrylic acid-itaconic acid, and their microbiological interactions.
PubMed:Bis-(2,5-diphenylphospholanes) with sp2 carbon linkers: synthesis and application in asymmetric hydrogenation.
PubMed:[The drug release properties of poly (acrylamide-co-itaconate-vinylbenzylglycosylallylamide) hydrogels].
PubMed:Asymmetric hydrogenation using monodentate phosphoramidite ligands.
PubMed:Effects of lactose and glucose on production of itaconic acid and lovastatin by Aspergillus terreus ATCC 20542.
PubMed:Isolation of Ashbya gossypii mutant for an improved riboflavin production targeting for biorefinery technology.
PubMed:Itaconic acid production using sago starch hydrolysate by Aspergillus terreus TN484-M1.
PubMed:Topography of the active site of the Saccharomyces cerevisiae plasmalemmal dicarboxylate transporter studied using lipophilic derivatives of its substrates.
PubMed:Redox silencing of the Fenton reaction system by an alkylitaconic acid, ceriporic acid B produced by a selective lignin-degrading fungus, Ceriporiopsis subvermispora.
PubMed:Inverted supercritical carbon dioxide/aqueous biphasic media for rhodium-catalyzed hydrogenation reactions.
PubMed:Highly enantioselective hydrogenation of alpha-dehydroamino esters and itaconates with triphosphorous bidentate ligands and the unprecedented solvent effect thereof.
PubMed:AccD6, a member of the Fas II locus, is a functional carboxyltransferase subunit of the acyl-coenzyme A carboxylase in Mycobacterium tuberculosis.
PubMed:Effect of supercritical CO2 in modified polystyrene 3D latex arrays.
PubMed:Virtual imprinting as a tool to design efficient MIPs for photosynthesis-inhibiting herbicides.
PubMed:Properties of succinyl-coenzyme A:D-citramalate coenzyme A transferase and its role in the autotrophic 3-hydroxypropionate cycle of Chloroflexus aurantiacus.
PubMed:Synthesis of UV-absorbing and fluorescent carrier ampholyte mixtures and their application for the determination of the operational pH values of buffering membranes used in isoelectric trapping separations.
PubMed:New polymeric materials for use in glass-ionomer cements.
PubMed:Catalytic ability of a cationic Ru(II) monochloro complex for the asymmetric hydrogenation of dimethyl itaconate and enamides.
PubMed:The release of bovine serum albumin from polyurethane based hydrophilic and hydrophobic disks and microbiological interactions.
PubMed:Factors affecting broadband acoustic emission measurements of a heterogeneous reaction.
PubMed:An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media.
PubMed:Purification and characterization of cis-aconitic acid decarboxylase from Aspergillus terreus TN484-M1.
PubMed:Efficient conversion of itaconic acid to (S)-(+)-citramalic acid by Alcaligenes xylosoxydans IL142.
PubMed:Process model and economic analysis of itaconic acid production from dimethyl succinate and formaldehyde.
PubMed:Swelling and paracetamol release studies of poly(acrylamide-co-itaconic acid) hydrogels.
PubMed:Polycarboxylic acid nanoparticles for ophthalmic drug delivery: an ex vivo evaluation with human cornea.
PubMed:Synthesis and application of phosphinoferrocenylaminophosphine ligands for asymmetric catalysis.
PubMed:Swelling behavior and mechanical properties of poly(acrylamide-co-itaconic acid) hydrogels and their semi-IPNS with poly(ethylene glycol).
PubMed:Novel method for cell immobilization and its application for production of organic acid.
PubMed:The molecular reaction vessels for a transesterification process created by molecular imprinting technique.
PubMed:Itaconate reduces visceral fat by inhibiting fructose 2,6-bisphosphate synthesis in rat liver.
PubMed:A molecularly imprinted catalyst designed by a computational approach in catalysing a transesterification process.
PubMed:Multi-maleimides bearing electron-donating chromophores: reversible fluorescence and aggregation behavior.
PubMed:Synthesis of new monodentate spiro phosphoramidite ligand and its application in Rh-catalyzed asymmetric hydrogenation reactions.
PubMed:H(2) production and carbon utilization by Thermotoga neapolitana under anaerobic and microaerobic growth conditions.
PubMed:Intracellular expression of Vitreoscilla hemoglobin in Aspergillus terreus to alleviate the effect of a short break in aeration during culture.
PubMed:Preparation of poly(N-isopropylacrylamide/itaconic acid) copolymeric hydrogels and their drug release behavior.
PubMed:Monitoring of a heterogeneous reaction by acoustic emission.
PubMed:Specific interactions study in complexes of poly(mono-n-alkyl itaconates) with tertiary polyamides.
PubMed:Monitoring of itaconic acid hydrogenation in a trickle bed reactor using fiber-optic coupled near-infrared spectroscopy.
PubMed:Ceriporic acid C, a hexadecenylitaconate produced by a lignin-degrading fungus, Ceriporiopsis subvermispora.
PubMed:Concise synthesis of (+/-)-horsfiline and (+/-)-coerulescine by tandem cyclisation of iodoaryl alkenyl azides.
PubMed:Transdermal application of bupivacaine-loaded poly(acrylamide(A)-co-monomethyl itaconate) hydrogels.
PubMed:[Determination of itaconic acid in culture broth by high performance liquid chromatography].
PubMed:Asymmetric hydrogenation of itaconic acid and enol acetate derivatives with the Rh-TangPhos catalyst.
PubMed:A novel chiral ferrocenyl phosphine ligand from sugar: applications in Rh-catalyzed asymmetric hydrogenation reactions.
PubMed:Chemical synthesis, iron redox interactions and charge transfer complex formation of alkylitaconic acids from Ceriporiopsis subvermispora.
PubMed:Inhibition of acetate and propionate assimilation by itaconate via propionyl-CoA carboxylase in isocitrate lyase-negative purple bacterium Rhodospirillum rubrum.
PubMed:A selective lignin-degrading fungus, Ceriporiopsis subvermispora, produces alkylitaconates that inhibit the production of a cellulolytic active oxygen species, hydroxyl radical in the presence of iron and H(2)O(2).
PubMed:Retention of alkali, alkaline earth and transition metals on an itaconic acid cation-exchange column. Eluent pH, ionic strength and temperature effects upon selectivity.
PubMed:Enhanced production of itaconic acid from corn starch and market refuse fruits by genetically manipulated Aspergillus terreus SKR10.
PubMed:Vibrio trachuri Iwamoto et al. 1995 is a junior synonym of Vibrio harveyi (Johnson and Shunk 1936) Baumann et al. 1981.
PubMed:Production of new unsaturated lipids during wood decay by ligninolytic basidiomycetes.
PubMed:Solid-phase synthesis of alpha-substituted 3-bisarylthio N-hydroxy propionamides as specific MMP inhibitors.
PubMed:The biochemistry of citric acid accumulation by Aspergillus niger.
PubMed:Identification of a novel series of alkylitaconic acids in wood cultures of Ceriporiopsis subvermispora by gas chromatography/mass spectrometry.
PubMed:Copolymers of itaconic anhydride and methacrylate-terminated poly(lactic acid) macromonomers.
PubMed:Controlled release of antifungal drug terbinafine hydrochloride from poly(N-vinyl 2-pyrrolidone/itaconic acid) hydrogels.
PubMed:Biotechnological production of itaconic acid.
PubMed:Aggressiveness of contemporary self-etching adhesives. Part II: etching effects on unground enamel.
PubMed:Isotachophoretic separation behavior of rare-earth EDTA chelates and analysis of minor rare-earth elements in an iron ore by bidirectional isotachophoresis-particle-induced X-ray emission.
PubMed:The effect of acid etching on vascular diameter of pulp-vessels in rat incisor (vitalmicroscopic study).
PubMed:Thermoprecipitation of lysozyme from egg white using copolymers of N-isopropylacrylamide and acidic monomers.
PubMed:Effect of pH and stirring rate on itaconate production by Aspergillus terreus.
PubMed:Hydrogen bonding isosteres: bimolecular carboxylic acid and amine-N-oxide interactions mediated via CH...O hydrogen bonds.
PubMed:[Physical properties of apatite bone cement].
PubMed:Synthesis of chiral hydroxyl phospholanes from D-mannitol and their use in asymmetric catalytic reactions.
PubMed:Effects of a nonrinse conditioner and 17% ethylenediaminetetraacetic acid on the etch pattern of intact human permanent enamel.
PubMed:Direct enantioseparation of adrenergic drugs via thin-layer chromatography using molecularly imprinted polymers.
PubMed:Production of multifunctional organic acids from renewable resources.
PubMed:Effect of contamination and etching on enamel bond strength of new light-cured glass ionomer cements.
PubMed:Kinetic Influences on Enantioselectivity for Non-Diastereopure Catalyst Mixtures.
PubMed:Qualitative identification of fumaric Acid and itaconic Acid in emulsion polymers.
PubMed:5-Fluorouracil release from copolymeric hydrogels of itaconic acid monoester. I. Acrylamide-co-monomethyl itaconate.
PubMed:Release of 5-fluorouracil from poly(acrylamide-co-monopropyl itaconate) hydrogels.
PubMed:In vitro swelling studies and preliminary biocompatibility evaluation of acrylamide-based hydrogels.
PubMed:Preparation of glass ionomer cement using N-acryloyl-substituted amino acid monomers--evaluation of physical properties.
PubMed:Itaconate biosynthesis in Aspergillus terreus.
PubMed:Potent promoting activity of dimethylitaconate on gastric carcinogenesis induced by N-methylnitrosourea.
PubMed:Novel psi-S-CH2 peptide-bond replacement and its utilization in the synthesis of nonpeptidic surrogates of the Leu-Asp-Val sequence that exhibit specific inhibitory activities on CD4+ T cell binding to fibronectin.
PubMed:A new NMR airlift bioreactor used in 31P-NMR studies of itaconic acid producing Aspergillus terreus.
PubMed:Biocompatibility of tetracalcium phosphate cement when used as a bone substitute.
PubMed:Polymeric calcium phosphate cements: analysis of reaction products and properties.
PubMed:Substrate-decreased modification by diethyl pyrocarbonate of two histidines in isocitrate lyase from Escherichia coli.
PubMed:Simultaneous saccharification and fermentation of cellulose to lactic acid.
PubMed:Continuous itaconic acid production by immobilized biocatalysts.
PubMed:GABA agonists and uptake inhibitors. Synthesis, absolute stereochemistry, and enantioselectivity of (R)-(-)- and (S)-(+)-homo-beta-proline.
PubMed:The role of the citric acid cycle in fungal organic acid fermentations.
PubMed:A new ion exchanger with high in vivo sodium capacity.
PubMed:Enzymes of vitamin B6 degradation. Purification and properties of two N-acetylamidohydrolases.
PubMed:Inhibition of isocitrate lyase by 3-nitropropionate, a reaction-intermediate analogue.
PubMed:[Contribution to the problem of preventing recurrences of oxalate and phosphate urinary caluli: active modification of citrate excretion and Ca++-binding capacity in the urine of Wistar rats].
PubMed:Glyoxylate bypass enzymes in Yersinia species and multiple forms of isocitrate lyase in Yersinia pestis.
PubMed:Taurine catabolism. III. Evidence for the participation of the glyoxylate cycle.
PubMed:Glyoxylate cycle in Mucor racemosus.
PubMed:Glass-ionomer cement formulations. II. The synthesis of novel polycarobxylic acids.
PubMed:13C NMR spectroscopic analysis of poly(electrolyte) cement liquids.
PubMed:Itaconic acid carrier ampholytes for isoelectric focusing.
PubMed:The production of itaconic acid and tetronic acids with respect to the growth cycle of Penicillium charlesii.
PubMed:Reinforced polycarboxylate cements.
PubMed:Mycological production of itaconic acid. 3. Role of mineral elements and alcohols.
PubMed:Mycological production of itaconic acid. II. Suitability of some carbon and nitrogen sources.
PubMed:Mycological production of itaconic acid. I. Effect of temperature, pH and incubation period.
PubMed:Corn steep liquor value for itaconic acid fermentation.
PubMed:Polarography of lead itaconate complexes.
PubMed:Biosynthesis of itaconic acid by aspergillus terreus.
PubMed:Catabolism of itaconic acid by preformed mats of Aspergillus terreus.
PubMed:Noninductive metabolism of itaconic acid by Pseudomonas and Salmonella species.
PubMed:[On the fermentation of itaconic acid by liver homogenates].
PubMed:The metabolism of itaconic acid by liver mitochondria.
PubMed:Biosynthesis of itaconic acid in Aspergillus terreus. III. The properties and reaction mechanism of cis-aconitic acid decarboxylase.
PubMed:Biosynthesis of itaconic acid in Aspergillus terreus. II. Early stages in glucose dissimilation and the role of citrate.
PubMed:Biosynthesis of itaconic acid in Aspergillus terreus. I. Tracer studies with C14-labeled substrates.
PubMed:Itaconic acid in organic chemistry. I. Synthesis of 2-methyl-1, 4-naphthoquinone (menadione).
PubMed:The mechanism of itaconic acid formation by Aspergillus terreus. 2. The effect of substrates and inhibitors.
PubMed:The mechanism of itaconic acid formation by Aspergillus terreus. 1. The effect of acidity.
PubMed:The inhibitory effects of itaconic acid in vitro and in vivo.
PubMed:Production of itaconic acid and kojic acid by a species of Aspergillus.
PubMed:Pharmacology of itaconic acid and its sodium, magnesium, and calcium salts.
PubMed:Some factors affecting the production of itaconic acid by Aspergillus terreus in agitated cultures.
PubMed:Studies in the biochemistry of micro-organisms: Itaconic acid, a metabolic product of a strain of Aspergillus terreus Thom.
Isol. from plants, e.g. roots of Vicia faba Itaconic acid, or methylenesuccinic acid, is an organic compound that is one of the three acids obtained by the distillation of citric acid.
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