EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes


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CAS Number: 1453-82-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:215-926-2
Nikkaji Web:J68.789H
Beilstein Number:0002173
XlogP3:-0.30 (est)
Molecular Weight:122.12702000
Formula:C6 H6 N2 O
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 155.00 °C. @ 760.00 mm Hg
Boiling Point: 334.40 °C. @ 760.00 mm Hg (est)
Flash Point: 313.00 °F. TCC ( 156.00 °C. ) (est)
logP (o/w): -0.280
Soluble in:
 water, 1.709e+005 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning
BOC Sciences
For experimental / research use only.
isonicotinamide N/A
Santa Cruz Biotechnology
For experimental / research use only.
isoNiacinamide ≥99%
Sigma-Aldrich: Aldrich
For experimental / research use only.
isoNicotinamide ReagentPlus®, 99%
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic agents
Recommendation for isoniacinamide usage levels up to:
 not for fragrance use.
Recommendation for isoniacinamide flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA Substance Registry Services (TSCA):1453-82-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :15074
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
RTECS:NR9500000 for cas# 1453-82-3
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):15074
Pubchem (sid):134980173
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
UM BBD:Search
KEGG (GenomeNet):C02421
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2933.39.4700
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
isonicotinic acid amide


Google Patents:Multicomponent crystalline system comprising deferasirox and isonicotinamide and a process for the preparation thereof
PubMed:Antitubercular activity of Ru (II) isoniazid complexes.
PubMed:Improving the dissolution and bioavailability of 6-mercaptopurine via co-crystallization with isonicotinamide.
PubMed:Potential of multisyringe chromatography for the on-line monitoring of the photocatalytic degradation of antituberculosis drugs in aqueous solution.
PubMed:Synthesis and anti-mycobacterial activity of new 4-thiazolidinone and 1,3,4-oxadiazole derivatives of isoniazid.
PubMed:Large thermal hysteresis for iron(II) spin crossover complexes with N-(pyrid-4-yl)isonicotinamide.
PubMed:Structures and spectroscopic characterization of calcium chloride-nicotinamide, -isonicotinamide, -picolinamide and praseodymium bromide-nicotinamide complexes.
PubMed:A pillared framework coordination polymer based on the Cd3(μ3-OH) unit: poly[[(μ4-5-aminotetrazolato-κ(4)N(1):N(2):N(3):N(4))chlorido-μ3-hydroxido-(μ3-isonicotinato-κ(3)N:O:O')dicadmium(II)] 0.14-hydrate].
PubMed:Self-association during heterogeneous nucleation onto well-defined templates.
PubMed:Discovery of MK-3697: a selective orexin 2 receptor antagonist (2-SORA) for the treatment of insomnia.
PubMed:A Lewis acid-mediated conformational switch.
PubMed:Targeted structure modulation of "pillar-layered" metal-organic frameworks for CO₂ capture.
PubMed:Acemetacin cocrystals and salts: structure solution from powder X-ray data and form selection of the piperazine salt.
PubMed:Photophysics of bis-bipyridyl nitro complexes of ruthenium(II) with pyridine ligands: substituent effects.
PubMed:Novel modified carbon nanotubes as a selective sorbent for preconcentration and determination of trace copper ions in fruit samples.
PubMed:Diversity-oriented synthesis yields a new drug lead for treatment of chagas disease.
PubMed:Orally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinib.
PubMed:Incidence of mucositis in patients treated with temsirolimus-based regimens and correlation to treatment response.
PubMed:Structural landscape of the 1 : 1 benzoic acid : isonicotinamide cocrystal.
PubMed:Protective effects of a nicotinamide derivative, isonicotinamide, against streptozotocin-induced β-cell damage and diabetes in mice.
PubMed:Preparation and characterization of a novel Wells-Dawson heteropolyacid-based magnetic inorganic-organic nanohybrid catalyst H6P2W18O62/pyridino-Fe3O4 for the efficient synthesis of 1-amidoalkyl-2-naphthols under solvent-free conditions.
PubMed:A 1:2 cocrystal of genistein with isonicotinamide: crystal structure and Hirshfeld surface analysis.
PubMed:The MEK1/2 inhibitor AS703026 circumvents resistance to the BRAF inhibitor PLX4032 in human malignant melanoma cells.
PubMed:N-Methylanilide and N-methylbenzamide derivatives as phosphodiesterase 10A (PDE10A) inhibitors.
PubMed:Novel agents and future prospects in the treatment of pancreatic adenocarcinoma.
PubMed:Bis(μ-4-formyl-benzoato-κ(2) O:O')bis-[(4-formyl-benzoato-κ(2) O,O')bis-(iso-nicotin-amide-κN (1))copper(II)].
PubMed:trans-Tetra-aqua-bis-(isonicotinamide-κN (1))zinc bis-(3-hy-droxy-benzoate) tetra-hydrate.
PubMed:Spirocyclic dihydropyridines by electrophile-induced dearomatizing cyclization of N-alkenyl pyridinecarboxamides.
PubMed:catena-Poly[[aquabis[N-(pyridin-3-yl)isonicotinamide-κN (1)]copper(II)]-μ-fumarato-κ(2) O (1):O (4)].
PubMed:Surface-enhanced Raman scattering of picolinamide, nicotinamide, and isonicotinamide: unusual carboxamide deprotonation under adsorption on silver nanoparticles.
PubMed:L2,3-edge x-ray absorption near-edge spectroscopy analysis of photoisomerism in solid ruthenium-sulfur dioxide complexes.
PubMed:cis-(2,2'-Bipyridine-κ(2)N,N')bis-(isonicotinamide-κN(1))palladium(II) bis-(hexa-fluoridophosphate).
PubMed:4-Carbamoylpyridin-1-ium 2,2,2-tri-chloro-acetate-isonicotinamide (1/1).
PubMed:Selective detection of multicarboxylate anions based on "turn on" electron transfer by self-assembled molecular rectangles.
PubMed:Two ligand-functionalized Pb(II) metal-organic frameworks: structures and catalytic performances.
PubMed:Systematic evaluation of textural properties, activation temperature and gas uptake of Cu2(pzdc)2L [L = dipyridyl-based ligands] porous coordination pillared-layer networks.
PubMed:Anticancer Activity of Self-Assembled Molecular Rectangles via Arene-Ruthenium Acceptors and a New Unsymmetrical Amide Ligand.
PubMed:Unusual co-crystal of isonicotinamide: the structural landscape in crystal engineering.
PubMed:Isonicotinamide enhances Sir2 protein-mediated silencing and longevity in yeast by raising intracellular NAD+ concentration.
PubMed:Nocardia globerula NHB-2 nitrilase catalysed biotransformation of 4-cyanopyridine to isonicotinic acid.
PubMed:Isonicotinamide self-association: the link between solvent and polymorph nucleation.
PubMed:Novel acridinedione derivatives: design, synthesis, SIRT1 enzyme and tumor cell growth inhibition studies.
PubMed:Synthesis of highly potent novel anti-tubercular isoniazid analogues with preliminary pharmacokinetic evaluation.
PubMed:catena-Poly[[(μ-3-hy-droxy-benzoato-κO,O:O)(μ-3-hy-droxy-benzoato-κO,O:O)(isonicotinamide-κN)-lead(II)] monohydrate].
PubMed:trans-Tetra-aqua-bis-(isonicotinamide-κN)cobalt(II) bis-(3-hy-droxy-benzoate) tetra-hydrate.
PubMed:Mechanical stress-activated immune response genes via Sirtuin 1 expression in human periodontal ligament cells.
PubMed:trans-Tetra-aqua-bis-(isonicotinamide-κN)nickel(II) bis-(3-hy-droxy-benzoate) tetra-hydrate.
PubMed:Isonicotinamide-2-naphthoic acid (1/1).
PubMed:Novel furosemide cocrystals and selection of high solubility drug forms.
PubMed:Coordination-driven self-assembly of 2D-metallamacrocycles using a shape-selective Pt(II)2-organometallic 90° acceptor: design, synthesis and sensing study.
PubMed:Isoniazid metal complex reactivity and insights for a novel anti-tuberculosis drug design.
PubMed:Nuclear quadrupole resonance study of hydrogen bonded solid materials.
PubMed:Cocrystals of quercetin with improved solubility and oral bioavailability.
PubMed:Extending the supramolecular synthon based fragment approach (SBFA) for transferability of multipole charge density parameters to monofluorobenzoic acids and their cocrystals with isonicotinamide: importance of C-H···O, C-H···F, and F···F intermolecular regions.
PubMed:Antinociceptive and anti-inflammatory activities of nicotinamide and its isomers in different experimental models.
PubMed:The role of sirtuin 1 in osteoblastic differentiation in human periodontal ligament cells.
PubMed:Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation.
PubMed:Microwave assisted one-pot synthesis of highly potent novel isoniazid analogues.
PubMed:MEK1/2 inhibitors AS703026 and AZD6244 may be potential therapies for KRAS mutated colorectal cancer that is resistant to EGFR monoclonal antibody therapy.
PubMed:New polymorphs of isonicotinamide and nicotinamide.
PubMed:14N NQR study of polymorphism and hydrogen bonding in molecular complex isonicotinamide-oxalic acid (2:1).
PubMed:Antimycobacterial and antitumor activities of palladium(II) complexes containing isonicotinamide (isn): X-ray structure of trans-[Pd(N3)2(isn)(2)].
PubMed:Solubility, metastable zone width measurement and crystal growth of the 1:1 benzoic acid/isonicotinamide cocrystal in solutions of variable stoichiometry.
PubMed:Structure elucidation of highly polar basic degradants by on-line hydrogen/deuterium exchange hydrophilic interaction chromatography coupled to tandem mass spectrometry.
PubMed:Synthesis and in vitro evaluation of substituted pyrimido[5,4-d]pyrimidines as a novel class of anti-Mycobacterium tuberculosis agents.
PubMed:Direct electrochemistry of cytochrome c at modified Si(100) electrodes.
PubMed:Blockade of the MEK/ERK signalling cascade by AS703026, a novel selective MEK1/2 inhibitor, induces pleiotropic anti-myeloma activity in vitro and in vivo.
PubMed:Bis(isonicotinamide-κN)bis-(4-methyl-benzoato-κO)copper(II) dihydrate.
PubMed:Aqua-bis(isonicotinamide-κN)bis-(4-methyl-benzoato)-κO;κO,O'-cadmium(II) monohydrate.
PubMed:Experimental and theoretical charge density study of polymorphic isonicotinamide-oxalic acid molecular complexes with strong O...H...N hydrogen bonds.
PubMed:Multinuclear NMR and theoretical investigation on interactions between diperoxovanadate complex and 4-picoline-like ligands.
PubMed:Biochemical effects of SIRT1 activators.
PubMed:One-pot mechanosynthesis with three levels of molecular self-assembly: coordination bonds, hydrogen bonds and host-guest inclusion.
PubMed:Uncommon isonicotinamide supramolecular synthons in copper(II) complexes directed by nitrate and perchlorate anions.
PubMed:Activation of SIRT1 by resveratrol represses transcription of the gene for the cytosolic form of phosphoenolpyruvate carboxykinase (GTP) by deacetylating hepatic nuclear factor 4alpha.
PubMed:Experimental chemotherapy against Trypanosoma cruzi infection using ruthenium nitric oxide donors.
PubMed:Continuous hydrolysis of 4-cyanopyridine by nitrilases from Fusarium solani O1 and Aspergillus niger K10.
PubMed:Effect of soft segment crystallization and hard segment physical crosslink on shape memory function in antibacterial segmented polyurethane ionomers.
PubMed:Resveratrol inhibits proliferation and promotes apoptosis of osteosarcoma cells.
PubMed:Zero-, one- and two-dimensional hydrogen-bonded structures in the 1:1 proton-transfer compounds of 4,5-dichlorophthalic acid with the monocyclic heteroaromatic Lewis bases 2-aminopyrimidine, nicotinamide and isonicotinamide.
PubMed:Aqua-bis(4-formyl-benzoato-κO,O)bis-(isonicotinamide-κN)cadmium(II) monohydrate.
PubMed:Bis(isonicotinamide-κN)bis-[4-(methyl-amino)benzoato]zinc(II) monohydrate.
PubMed:Tetra-aqua-bis(isonicotinamide-κN)cobalt(II) bis-(4-formyl-benzoate) dihydrate.
PubMed:Tetra-aqua-bis(isonicotinamide-κN)nickel(II) bis-(4-formyl-benzoate) dihydrate.
PubMed:Design, synthesis, and characterizations of a series of Pt(4) macrocycles and fluorescent sensing of Fe3+/Cu2+/Ni2+ through metal coordination.
PubMed:Chiral carboxylic acids and their effects on melting-point behaviour in co-crystals with isonicotinamide.
PubMed:Self-assembly of electroactive thiacrown ruthenium(II) complexes into hydrogen-bonded chain and tape networks.
PubMed:Oxidation of catechin and rutin by pentaammineruthenium(III) complexes.
PubMed:Nitrosation of N-methylhydroxylamine by nitroprusside. A kinetic and mechanistic study.
PubMed:Zipped-up chain-type coordination polymers: unsymmetrical amide-containing ligands inducing beta-sheet or helical structures.
PubMed:Design and synthesis of 6-fluoro-2-naphthyl derivatives as novel CCR3 antagonists with reduced CYP2D6 inhibition.
PubMed:Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells.
PubMed:Electrophile-induced dearomatizing spirocyclization of N-arylisonicotinamides: a route to spirocyclic piperidines.
PubMed:A structure-activity analysis of the variation in oxime efficacy against nerve agents.
PubMed:NMR and theoretical study on interactions between diperoxovanadate complex and 4-substituted pyridines.
PubMed:Isoniazid: metabolic aspects and toxicological correlates.
PubMed:Molecular structure, vibrational spectra, quantum chemical calculations and photochemistry of picolinamide and isonicotinamide isolated in cryogenic inert matrixes and in the neat low-temperature solid phases.
PubMed:14N NQR study of nicotinamide and related compounds.
PubMed:Metalloporphyrin-based inclusion materials: exploiting ligating topologies and hydrogen-bonding backbones in generating new supramolecular architectures.
PubMed:A novel oral indoline-sulfonamide agent, N-[1-(4-methoxybenzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule.
PubMed:Synthesis and structure of silver complexes with nicotinate-type ligands having antibacterial activities against clinically isolated antibiotic resistant pathogens.
PubMed:Discovery of isonicotinamide derived beta-secretase inhibitors: in vivo reduction of beta-amyloid.
PubMed:Discovery and SAR of isonicotinamide BACE-1 inhibitors that bind beta-secretase in a N-terminal 10s-loop down conformation.
PubMed:Ligand-based design, synthesis and primary in vivo screening of pyrrole derivatives as potential tricyclic anti-inflammatory agents.
PubMed:A regenerable ruthenium tetraammine nitrosyl complex immobilized on a modified silica gel surface: preparation and studies of nitric oxide release and nitrite-to-NO conversion.
PubMed:LC and LC-MS study of stress decomposition behaviour of isoniazid and establishment of validated stability-indicating assay method.
PubMed:Utilization of host SR protein kinases and RNA-splicing machinery during viral replication.
PubMed:The amide rotational barrier in isonicotinamide: Dynamic NMR and ab initio studies.
PubMed:Activation of Sirt1 decreases adipocyte formation during osteoblast differentiation of mesenchymal stem cells.
PubMed:[Modulation of reactivity of cyclic adenosine monophosphate phosphodiesterase under the effect of pyridinecarboxylic acid derivatives and Pt(IV) metal complexes on their basis].
PubMed:Catalase-peroxidase of Mycobacterium bovis BCG converts isoniazid to isonicotinamide, but not to isonicotinic acid: differentiation parameter between enzymes of Mycobacterium bovis BCG and Mycobacterium tuberculosis.
PubMed:Carboxamide-pyridine N-oxide heterosynthon for crystal engineering and pharmaceutical cocrystals.
PubMed:Proton sharing in bis(4-carbamoylpyridinium) squarate.
PubMed:Practical synthesis of a neuropeptide Y antagonist via stereoselective addition to a ketene.
PubMed:catena-Poly[[[diaquabis(pyridine-4-carboxamide-kappaN)copper(II)]-mu2-squarato-kappaO1:O3] dihydrate].
PubMed:Synthesis and characterization of hydrogen-bonded assemblies of W6S8L6 clusters.
PubMed:Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition.
PubMed:Nonpolymeric hydrogelator derived from N-(4-pyridyl)isonicotinamide.
PubMed:Selectivity of effects of redox-active cobalt(III) complexes on tumor tissue.
PubMed:A contrivance for a dynamic porous framework: cooperative guest adsorption based on square grids connected by amide-amide hydrogen bonds.
PubMed:Structure-based optimization of novel azepane derivatives as PKB inhibitors.
PubMed:Self-assembly in palladium(II) and platinum(II) chemistry: the biomimetic approach.
PubMed:Hydrogen-bonded extended arrays of the [Re6(mu3-Se)8]2+ core-containing clusters.
PubMed:Ruthenium bisbipyridine complexes of horse heart cytochrome c: characterization and comparative intramolecular electron-transfer rates determined by pulse radiolysis and flash photolysis.
PubMed:(Acetonitrile)[2,6-bis(pyrazol-1-yl)pyridine](isonicotinamide)copper(II)-tetrafluoroborate-acetonitrile (1/2/2).
PubMed:Variation in the coordination mode of arenedisulfonates: syntheses and structural characterization of mononuclear and dinuclear cadmium(II) arenedisulfonate complexes with two- to zero-dimensional architectures.
PubMed:Novel flexible frameworks of porous cobalt(II) coordination polymers that show selective guest adsorption based on the switching of hydrogen-bond pairs of amide groups.
PubMed:Copper complexes with bioactive ligands. Part II--Antifungal activity.
PubMed:Mn(III) pyrophosphate as an efficient tool for studying the mode of action of isoniazid on the InhA protein of Mycobacterium tuberculosis.
PubMed:Cooperative ligation, back-bonding, and possible pyridine-pyridine interactions in tetrapyridine-vanadium(II): a visible and X-ray spectroscopic study.
PubMed:Copper complexes with bioactive ligands Part I--Antimicrobial activity.
PubMed:Kinetics and mechanism of ligand interchange in pentacyano-L-osmate(II) complexes (L = H(2)O, NH(3), N-heterocyclic ligands).
PubMed:Self-assembly of polymer and sheet structures from palladium(II) complexes by hydrogen bonding between carboxamide substituents.
PubMed:Inhibition of cancer cell growth by ruthenium(II) arene complexes.
PubMed:Oxidation of [Ru(NH3)5isn](BF4)2 by hyochlorous acid and chlorine in aqueous acidic media.
PubMed:Synthesis and characterization of non-leaching biocidal polyurethanes.
PubMed:Molecularly imprinted polymers from nicotinamide and its positional isomers.
PubMed:Surface-enhanced raman spectra of some anti-tubercle bacillus drugs.
PubMed:Apoptosis induced by niacin-related compounds in K562 cells but not in normal human lymphocytes.
PubMed:Apoptosis induced by nicotinamide-related compounds and quinolinic acid in HL-60 cells.
PubMed:[Vitamins and apoptosis--induction of apoptosis in human cancer cells by nicotinic acid-related compounds].
PubMed:Apoptosis induced by niacin-related compounds in HL-60 cells.
PubMed:A novel ternary ligand system for 99mTc-labeling of hydrazino nicotinamide-modified biologically active molecules using imine-N-containing heterocycles as coligands.
PubMed:Cloning and characterization of a probenazole-inducible gene for an intracellular pathogenesis-related protein in rice.
PubMed:Maintenance of phenobarbital-inducible Cyp2b gene expression in C57BL/6 mouse hepatocytes in primary culture as spheroids.
PubMed:Elevated expression of the Cyp1a2 gene in the presence of nicotinamide by adult mouse hepatocytes in primary culture.
PubMed:Translational activation of ethanol-inducible cytochrome P450 (CYP2E1) by isoniazid.
PubMed:Effects of nicotinamide and its isomers on iron-induced renal damage.
PubMed:Solubility enhancement of some water-insoluble drugs in the presence of nicotinamide and related compounds.
PubMed:[Fluorometric determination of pyridine and its derivatives by flow injection analysis].
PubMed:Abiotic transformations and decomposition kinetics of 4-carbamoyl-2'-[(hydroxyimino)methyl]-1,1'-(oxydimethylene)-bis(pyridin ium chloride) in aqueous phosphate buffers.
PubMed:Studies on the stability and decomposition of the Hagedorn-oxime HLö 7 in aqueous solution.
PubMed:The characterization of the protection by nicotinamide against the action of diabetogenic nitrosoureas.
PubMed:Pertussis toxin-sensitive cholinergic inhibition of somatostatin release from canine D-cells.
PubMed:Simultaneous micro-determination of nicotinamide and its major metabolites, N1-methyl-2-pyridone-5-carboxamide and N1-methyl-4-pyridone-3-carboxamide, by high-performance liquid chromatography.
PubMed:Pertussis toxin facilitates secretagogue-induced catecholamine release from cultured bovine adrenal chromaffin cells.
PubMed:Studies on the decomposition of the oxime HI 6 in aqueous solution.
PubMed:Stability studies of bis(pyridiniumaldoxime) reactivators of organophosphate-inhibited acetylcholinesterase.
PubMed:Activation of guanylate cyclase by E. coli heat-stable enterotoxin (STa). Modulation by NAD and pertussis toxin.
PubMed:NADP+ enhances cholera and pertussis toxin-catalyzed ADP-ribosylation of membrane proteins.
PubMed:Evidence for the generation of active oxygen by isoniazid treatment of extracts of Mycobacterium tuberculosis H37Ra.
PubMed:Conversion of adrenergic mechanism from an alpha- to a beta-type during primary culture of rat hepatocytes. Accompanying decreases in the function of the inhibitory guanine nucleotide regulatory component of adenylate cyclase identified as the substrate of islet-activating protein.
PubMed:Purification of NADPH-dependent enoyl-CoA reductase involved in the malonyl-CoA dependent fatty acid elongation system of Mycobacterium smegmatis.
PubMed:Lack of carcinogenicity of nicotinamide and isonicotinamide following lifelong administration to mice.
PubMed:Effects of nicotinamide, isonicotinamide, and bleomycin on DNA synthesis and repair in rat hepatocytes and hepatoma cells.
PubMed:Reversed phase high-performance liquid chromatography of heterocyclic aromatic N-oxides: application to measurement of N-oxidation by microsomes and rat hepatocytes in primary culture.
PubMed:Evidence that ligand formation is a mechanism underlying the maintenance of cytochrome P-450 in rat liver cell culture. Potent maintenance by metyrapone.
PubMed:Tissue distribution and metabolism of drugs V: effect of secretin and pancreozymin on drug transport in rabbit pancreas.
PubMed:Relationship between the ability of nicotinamide to maintain nicotinamide-adenine dinucleotide in rat liver cell culture and its effect on cytochrome P-450.
PubMed:Effect of various alcohols on the intramuscular absorption of isonicotinamide in the rat.
PubMed:Antibodies specific to isoniazid and isonicotinic acid.
PubMed:The effect of dioxyphenylalanine (DOPA), amides and some potential sources of energy on the multiplication of Mycobacterium leprae.
PubMed:Effect of some ionic and nonionic surfactants on the intramuscular absorption of isonicotinamide.
PubMed:The actions of ambonestyl [N(2-diethylaminoethyl)-isonicotinamide] and quinidine on isolated rabbit atria.
PubMed:The effect of 2-diethylaminoethyl-isonicotinamide on cardiac arrhythmia in man.
PubMed:[Effect of 2-diethylaminoethyl isonicotinamide on some basic properties of myocardium & experimental arrhythmias].
PubMed:Pharmacologic and antiarrhythmic actions of ambonestyl (2-diethylaminoethyl-isonicotinamide) in man; preliminary report.
None found
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