hesperidin methyl chalcone
2-propen-1-one, 1-[4-[[6-O-(6-deoxy-a-L-mannopyranosyl)--D-glucopyranosyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)-, (2E)-
None found
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CAS Number: 24292-52-2Picture of molecule
Other: 25429-20-3
ECHA EINECS - REACH Pre-Reg: 246-128-2
MDL: MFCD00010438
XlogP3-AA: -0.30 (est)
Molecular Weight: 624.59392000
Formula: C29 H36 O15
Category: antioxidants
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 952.97 °C. @ 760.00 mm Hg (est)
Flash Point: 589.00 °F. TCC ( 309.50 °C. ) (est)
logP (o/w): 0.267 (est)
Soluble in:
 water, 692.9 mg/L @ 25 °C (est)
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Organoleptic Properties:
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antioxidants
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Santa Cruz Biotechnology
For experimental / research use only.
Hesperidin Methyl Chalcone
Sigma-Aldrich: Aldrich
For experimental / research use only.
Hesperidin Methyl Chalcone
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Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: antioxidants
Recommendation for hesperidin methyl chalcone usage levels up to:
 not for fragrance use.
Recommendation for hesperidin methyl chalcone flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
EPA Substance Registry Services (TSCA): 24292-52-2
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 6436550
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
Chemidplus: 0024292522
RTECS: FL7085000 for cas# 24292-52-2
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NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 6436550
Pubchem (sid): 135047171
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
Export Tariff Code: 2938.90.0000
ChemSpider: View
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Potential Blenders and core components note
None Found
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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 hesperidin methylchalcone
3-hydroxy-4-[(2E)-3-(3-hydroxy-4-methoxyphenyl)-2-propenoyl]-5-methoxyphenyl 6-O-(6-deoxy-a-L-mannopyranosyl)-β-D-glucopyranoside
2-propen-1-one, 1-[4-[[6-O-(6-deoxy-a-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-hydroxy-6-methoxyphenyl]-3-(3-hydroxy-4-methoxyphenyl)-, (2E)-
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PubMed: Quality of life improvement in Latin American patients suffering from chronic venous disorder using a combination of Ruscus aculeatus and hesperidin methyl-chalcone and ascorbic acid (quality study).
PubMed: Assessment of quality of life in Mexican patients suffering from chronic venous disorder - impact of oral Ruscus aculeatus-hesperidin-methyl-chalcone-ascorbic acid treatment - 'QUALITY Study'.
PubMed: Meta-analysis of clinical trials of Cyclo 3 Fort in the treatment of chronic venous insufficiency.
PubMed: An open-label, randomized multicenter study comparing the efficacy and safety of Cyclo 3 Fort versus hydroxyethyl rutoside in chronic venous lymphatic insufficiency.
PubMed: An open-label, randomised multicentre study comparing the efficacy and safety of CYCLO 3 FORT versus hydroxyethyl rutoside in chronic venous lymphatic insufficiency.
PubMed: Treatment of secondary lymphedema of the upper limb with CYCLO 3 FORT.
PubMed: A thin-layer chromatographic-fluorometric method for quantitative analysis of hesperidin methyl chalcone in parmaceuticals.
PubMed: Effect of hesperidin-methyl-chalcone on capillary resistance in the internal organs of the guinea pig and the rat.
PubMed: The effect of hesperidin methyl chalcone on the nervous control of the nictitating membrane.
PubMed: Effect of hesperidin methyl chalcone, vitamin P, on diabetic retinopathy.
PubMed: Administration of massive doses of vitamin P hesperidin methyl chalcone.
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