PubMed:Discriminative stimulus effects of the novel imidazoline I2 receptor ligand CR4056 in rats. |
PubMed:Alkaloids from the bulbs of Lycoris longituba and their neuroprotective and acetylcholinesterase inhibitory activities. |
PubMed:In situ label-free visualization of orally dosed strictinin within mouse kidney by MALDI-MS imaging. |
PubMed:Blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentration in dystonia cases vs. controls. |
PubMed:Efficient synthesis of an indoloquinolizinium alkaloid selective DNA-binder by ring-closing metathesis. |
PubMed:Nonaqueous capillary electrophoresis as separation technique to support metabolism studies by means of electrochemistry and mass spectrometry. |
PubMed:Inhibition of myeloperoxidase activity by the alkaloids of Peganum harmala L. (Zygophyllaceae). |
PubMed:Significance of the imidazoline receptors in toxicology. |
PubMed:Differential effects of non-nicotine tobacco constituent compounds on nicotine self-administration in rats. |
PubMed:Metabolites identification of harmane in vitro/in vivo in rats by ultra-performance liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry. |
PubMed:Aspidosperma (Apocynaceae) plant cytotoxicity and activity towards malaria parasites. Part I: Aspidosperma nitidum (Benth) used as a remedy to treat fever and malaria in the Amazon. |
PubMed:B-9-3, a novel β-carboline derivative exhibits anti-cancer activity via induction of apoptosis and inhibition of cell migration in vitro. |
PubMed:Inhibition of monoamine oxidase (MAO) by β-carbolines and their interactions in live neuronal (PC12) and liver (HuH-7 and MH1C1) cells. |
PubMed:["Legal highs" from the German internet--"bath salt drugs" on the rise]. |
PubMed:Elevated blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations in Parkinson's disease. |
PubMed:Dietary vitamin E effects on the formation of heterocyclic amines in grilled lean beef. |
PubMed:Fatty acid modulated human serum albumin binding of the β-carboline alkaloids norharmane and harmane. |
PubMed:Chemical state of heterocyclic aromatic amines in grilled beef: evaluation by in vitro digestion model and comparison of alkaline hydrolysis and organic solvent for extraction. |
PubMed:Suggesting a possible role of CA1 histaminergic system in harmane-induced amnesia. |
PubMed:Modulation in prototropism of the photosensitizer Harmane by host:guest interactions between β-cyclodextrin and surfactants. |
PubMed:Elevated brain harmane (1-methyl-9H-pyrido[3,4-b]indole) in essential tremor cases vs. controls. |
PubMed:Mechanisms of DNA damage by photoexcited 9-methyl-β-carbolines. |
PubMed:In vitro evaluation of β-carboline alkaloids as potential anti-Toxoplasma agents. |
PubMed:Participation of central imidazoline binding sites in antinociceptive effect of ethanol and nicotine in rats. |
PubMed:The alkaloid compound harmane increases the lifespan of Caenorhabditis elegans during bacterial infection, by modulating the nematode's innate immune response. |
PubMed:A QM/MM study of the absorption spectrum of harmane in water solution and interacting with DNA: the crucial role of dynamic effects. |
PubMed:Imidazoline versus alpha₂-adrenoceptors in the control of gastric motility in mice. |
PubMed:Antidepressant Potential of 5-HT3 Receptor Antagonist, N-n- propyl-3-ethoxyquinoxaline-2-carboxamide (6n). |
PubMed:Effect of harmane, an endogenous β-carboline, on learning and memory in rats. |
PubMed:Involvement of nitrergic system of CA1in harmane induced learning and memory deficits. |
PubMed:Simultaneous determination of alkaloids and flavonoids from aerial parts of Passiflora species and dietary supplements using UPLC-UV-MS and HPTLC. |
PubMed:Behavioural, neurochemical and neuroendocrine effects of the endogenous β-carboline harmane in fear-conditioned rats. |
PubMed:Blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentration in essential tremor cases in Spain. |
PubMed:Binding interaction and rotational-relaxation dynamics of a cancer cell photosensitizer with various micellar assemblies. |
PubMed:Profiles and concentrations of heterocyclic aromatic amines formed in beef during various heat treatments depend on the time of ripening and muscle type. |
PubMed:Blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations in essential tremor: repeat observation in cases and controls in New York. |
PubMed:Structural insights into cholinesterases inhibition by harmane β-carbolinium derivatives: a kinetics-molecular modeling approach. |
PubMed:Mass spectrometry of rhenium complexes: a comparative study by using LDI-MS, MALDI-MS, PESI-MS and ESI-MS. |
PubMed:Production and fragmentation of negative ions from neutral N-linked carbohydrates ionized by matrix-assisted laser desorption/ionization. |
PubMed:Differential interactions of a biological photosensitizer with liposome membranes having varying surface charges. |
PubMed:Photosensitization of DNA by β-carbolines: kinetic analysis and photoproduct characterization. |
PubMed:Neonaucline, a new indole alkaloid from the leaves of Ochreinauclea maingayii (Hook. f.) Ridsd. (Rubiaceae). |
PubMed:Detection of bioactive exometabolites produced by the filamentous marine cyanobacterium Geitlerinema sp. |
PubMed:The impact of dihydrogen phosphate anions on the excited-state proton transfer of harmane. Effect of β-cyclodextrin on these photoreactions. |
PubMed:Effects of apomorphine and β-carbolines on firing rate of neurons in the ventral pallidum in the rats. |
PubMed:Involvement of the cholinergic system of CA1 on harmane-induced amnesia in the step-down passive avoidance test. |
PubMed:Exploring the strength, mode, dynamics, and kinetics of binding interaction of a cationic biological photosensitizer with DNA: implication on dissociation of the drug-DNA complex via detergent sequestration. |
PubMed:Modulation of prototropic activity and rotational relaxation dynamics of a cationic biological photosensitizer within the motionally constrained bio-environment of a protein. |
PubMed:Blood harmane concentrations in 497 individuals relative to coffee, cigarettes, and food consumption on the morning of testing. |
PubMed:The Arabidopsis phi class glutathione transferase AtGSTF2: binding and regulation by biologically active heterocyclic ligands. |
PubMed:Inhibition of human cytochrome P450 enzymes 3A4 and 2D6 by β-carboline alkaloids, harmine derivatives. |
PubMed:Screening of non-polar heterocyclic amines in urine by microextraction in packed sorbent-fluorimetric detection and confirmation by capillary liquid chromatography. |
PubMed:Effects of harmane and other β-carbolines on apomorphine-induced licking behavior in rat. |
PubMed:Blood harmane, blood lead, and severity of hand tremor: evidence of additive effects. |
PubMed:Beta-carboline alkaloids and essential tremor: exploring the environmental determinants of one of the most prevalent neurological diseases. |
PubMed:Interaction of β-carboline alkaloids with RNA. |
PubMed:Relationship between blood harmane and harmine concentrations in familial essential tremor, sporadic essential tremor and controls. |
PubMed:Simultaneous determination of six non-polar heterocyclic amines in meat samples by supercritical fluid extraction-capillary electrophoresis under fluorimetric detection. |
PubMed:Beta-carboline alkaloids bind DNA. |
PubMed:Diamond, titanium dioxide, titanium silicon oxide, and barium strontium titanium oxide nanoparticles as matrixes for direct matrix-assisted laser desorption/ionization mass spectrometry analysis of carbohydrates in plant tissues. |
PubMed:Inhibitory effect of marinades with hibiscus extract on formation of heterocyclic aromatic amines and sensory quality of fried beef patties. |
PubMed:Involvement of dopamine D1/D2 receptors on harmane-induced amnesia in the step-down passive avoidance test. |
PubMed:Electrophysiological characterization of harmane-induced activation of mesolimbic dopamine neurons. |
PubMed:Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry analysis of oligosaccharides and oligosaccharide alditols obtained by hydrolysis of agaroses and carrageenans, two important types of red seaweed polysaccharides. |
PubMed:UV-MALDI-TOF mass spectrometry analysis of heparin oligosaccharides obtained by nitrous acid controlled degradation and high performance anion exchange chromatography. |
PubMed:A novel 5-HT(2A) receptor antagonist exhibits antidepressant-like effects in a battery of rodent behavioural assays: approaching early-onset antidepressants. |
PubMed:Molecular determinants of beta-carboline inhibition of the glycine receptor. |
PubMed:Optimized HPLC method for analysis of polar and nonpolar heterocyclic amines in cooked meat products. |
PubMed:One- and two-photon excitation of beta-carbolines in aqueous solution: pH-dependent spectroscopy, photochemistry, and photophysics. |
PubMed:1-(m-Chlorophenyl)piperazine induces depressogenic-like behaviour in rodents by stimulating the neuronal 5-HT(2A) receptors: proposal of a modified rodent antidepressant assay. |
PubMed:The effects of synthetic and endogenous imidazoline binding site ligands on neuronal activity in discrete brain regions of naive and restraint-stressed rats. |
PubMed:Antiplatelet activity of beta-carboline alkaloids from Perganum harmala: a possible mechanism through inhibiting PLCgamma2 phosphorylation. |
PubMed:The effect of temperature on the stability of compounds used as UV-MALDI-MS matrix: 2,5-dihydroxybenzoic acid, 2,4,6-trihydroxyacetophenone, alpha-cyano-4-hydroxycinnamic acid, 3,5-dimethoxy-4-hydroxycinnamic acid, nor-harmane and harmane. |
PubMed:Spectrofluorimetric determination of stoichiometry and association constants of the complexes of harmane and harmine with beta-cyclodextrin and chemically modified beta-cyclodextrins. |
PubMed:Effect of Peganum harmala or its beta-carboline alkaloids on certain antibiotic resistant strains of bacteria and protozoa from poultry. |
PubMed:In situ analysis of plant tissue underivatized carbohydrates and on-probe enzymatic degraded starch by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry by using carbon nanotubes as matrix. |
PubMed:Environmental epidemiology of essential tremor. |
PubMed:Cancer and blood concentrations of the comutagen harmane in essential tremor. |
PubMed:Influence of the presence of methyl cyclodextrins in high-performance liquid chromatography mobile phases on the separation of beta-carboline alkaloids. |
PubMed:Higher blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations correlate with lower olfactory scores in essential tremor. |
PubMed:Determination of beta-carboline alkaloids in fruiting bodies of Hygrophorus spp. by liquid chromatography/electrospray ionisation tandem mass spectrometry. |
PubMed:Dietary epidemiology of essential tremor: meat consumption and meat cooking practices. |
PubMed:Elevated blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations in essential tremor. |
PubMed:Mediterranean diet and essential tremor. A case-control study. |
PubMed:The endogenous alkaloid harmane: acidifying and activity-reducing effects on hippocampal neurons in vitro. |
PubMed:Coupled hydrogen-bonding interactions between beta-carboline derivatives and acetic acid. |
PubMed:Partial least squares-based multivariate spectral calibration method for simultaneous determination of beta-carboline derivatives in Peganum harmala seed extracts. |
PubMed:Blood harmane is correlated with cerebellar metabolism in essential tremor: a pilot study. |
PubMed:Structural characterization of native high-methoxylated pectin using nuclear magnetic resonance spectroscopy and ultraviolet matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Comparative use of 2,5-dihydroxybenzoic acid and nor-harmane as UV-MALDI matrices. |
PubMed:Synthesis of 3,8,9-trisubstituted-1,7,9-triaza-fluorene-6-carboxylic acid derivatives as a new class of insulin secretagogues. |
PubMed:Antioxidant properties of beta-carboline alkaloids are related to their antimutagenic and antigenotoxic activities. |
PubMed:Plasmodium falciparum biosynthesizes sulfoglycosphingolipids. |
PubMed:Quantification of the neurotoxic beta-carboline harmane in barbecued/grilled meat samples and correlation with level of doneness. |
PubMed:Determination of beta-carboline alkaloids in foods and beverages by high-performance liquid chromatography with electrochemical detection at a glassy carbon electrode modified with carbon nanotubes. |
PubMed:Validation of a new planar chromatographic method for quantification of the heterocyclic aromatic amines most frequently found in meat. |
PubMed:Electrodeposition of polythiophene assisted by sonochemistry and incorporation of fluorophores in the polymeric matrix. |
PubMed:A fluorescence study of the molecular interactions of harmane with the nucleobases, their nucleosides and mononucleotides. |
PubMed:Centrally acting imidazolines stimulate vascular alpha 1A-adrenergic receptors in Rat-Tail Artery. |
PubMed:A matrix-assisted laser desorption/ionization mass spectrometry approach to the lipid A from Mesorhizobium loti. |
PubMed:Imidazoline receptors, novel agents and therapeutic potential. |
PubMed:Autoradiographical distribution of imidazoline binding sites in monoamine oxidase A deficient mice. |
PubMed:Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine. |
PubMed:Comprehensive photochemistry and photophysics of land- and marine-based beta-carbolines employing time-resolved emission and flash transient spectroscopy. |
PubMed:Effect of chlorine as substituent on the photochemistry and acid-base properties of beta-carboline alkaloids. |
PubMed:Theoretical study of structure, pKa, lipophilicity, solubility, absorption, and polar surface area of some centrally acting antihypertensives. |
PubMed:In vitro and ex vivo distribution of [3H]harmane, an endogenous beta-carboline, in rat brain. |
PubMed:Antidepressant-like effect of harmane and other beta-carbolines in the mouse forced swim test. |
PubMed:Harmane inhibits serotonergic dorsal raphe neurons in the rat. |
PubMed:Characterisation of imidazoline I2 binding sites in pig brain. |
PubMed:Blood harmane concentrations and dietary protein consumption in essential tremor. |
PubMed:Structural analysis of the N-glycans of the major cysteine proteinase of Trypanosoma cruzi. Identification of sulfated high-mannose type oligosaccharides. |
PubMed:Matrix-assisted laser desorption/ionisation mass spectrometry for the direct analysis of enzymatically digested kappa- iota- and hybrid iota/nu-carrageenans. |
PubMed:Photochemistry of the alkaloids eudistomin N (6-bromo-nor-harmane) and eudistomin O (8-bromo-nor-harmane) and other bromo-beta-carbolines. |
PubMed:Fluorescence quenching of beta-carboline alkaloids in micellar media. A study to select the adequate surfactant to use in analytical techniques. |
PubMed:Matrix-assisted ultraviolet laser desorption/ionization time-of-flight mass spectrometry of beta-(1 --> 3), beta-(1 --> 4)-xylans from Nothogenia fastigiata using nor-harmane as matrix. |
PubMed:Modulation of voltage-gated channel currents by harmaline and harmane. |
PubMed:Harmane and harmalan are bioactive components of classical clonidine-displacing substance. |
PubMed:The putative imidazoline receptor agonist, harmane, promotes intracellular calcium mobilisation in pancreatic beta-cells. |
PubMed:In vitro activity of the beta-carboline alkaloids harmane, harmine, and harmaline toward parasites of the species Leishmania infantum. |
PubMed:Endogenous imidazoline receptor ligands relax rat aorta by an endothelium-dependent mechanism. |
PubMed:Harmane induces anxiolysis and antidepressant-like effects in rats. |
PubMed:Effect of harmane on the convulsive threshold in epilepsy models in mice. |
PubMed:Inhibitory effect of harmane on morphine-dependent Guinea pig ileum. |
PubMed:Effect of harmane on mononeuropathic pain in rats. |
PubMed:Characterization of [(3)H]harmane binding to rat whole brain membranes. |
PubMed:Comparative effects of efaroxan and beta-carbolines on the secretory activity of rodent and human beta cells. |
PubMed:Endogenous beta-carbolines as clonidine-displacing substances. |
PubMed:The effects of imidazoline agents on the aggregation of human platelets. |
PubMed:Effects of the beta-carbolines, harmane and pinoline, on insulin secretion from isolated human islets of Langerhans. |
PubMed:Detection and characterization of cyclodextrin complexes with beta-carboline derivatives by spectroscopic techniques. |
PubMed:Elevation of blood beta-carboline alkaloids in essential tremor. |
PubMed:Dynamic study of excited state hydrogen-bonded complexes of harmane in cyclohexane-toluene mixtures. |
PubMed:Matrix-assisted ultraviolet laser-desorption ionization and electrospray-ionization time-of-flight mass spectrometry of sulfated neocarrabiose oligosaccharides. |
PubMed:An in vitro evaluation of human DNA topoisomerase I inhibition by Peganum harmala L. seeds extract and its beta-carboline alkaloids. |
PubMed:5-HT2A receptor-stimulated phosphoinositide hydrolysis in the stimulus effects of hallucinogens. |
PubMed:Characterization of the discriminable stimulus produced by 2-BFI: effects of imidazoline I(2)-site ligands, MAOIs, beta-carbolines, agmatine and ibogaine. |
PubMed:Toxicokinetics of tremorogenic natural products, harmane and harmine, in male Sprague-Dawley rats. |
PubMed:Stimulatory effect of harmane and other beta-carbolines on locus coeruleus neurons in anaesthetized rats. |
PubMed:Hydrogen bonding NH/pi interactions between betacarboline and methyl benzene derivatives. |
PubMed:Matrix-assisted ultraviolet laser-desorption ionization time-of-flight mass spectrometry of sulfated mannans from the red seaweed Nothogenia fastigiata. |
PubMed:Autoradiographic comparison of [3H]-clonidine binding to non-adrenergic sites and alpha(2)-adrenergic receptors in human brain. |
PubMed:Harmane produces hypotension following microinjection into the RVLM: possible role of I(1)-imidazoline receptors. |
PubMed:Determination of harmane and harmine in human blood using reversed-phased high-performance liquid chromatography and fluorescence detection. |
PubMed:A spectroscopic study of the molecular interactions of harmane with pyrimidine and other diazines. |
PubMed:Indole derivatives as neuroprotectants. |
PubMed:A comparison of N,N-dimethyltryptamine, harmaline, and selected congeners in rats trained with LSD as a discriminative stimulus. |
PubMed:A spectroscopic study of the hydrogen bonding and pi-pi stacking interactions of harmane with quinoline. |
PubMed:The effects of beta-carbolines in rats trained with ibogaine as a discriminative stimulus. |
PubMed:beta-Carboline alkaloids as matrices for UV-matrix-assisted laser desorption/ionization time-of-flight mass spectrometry in positive and negative ion modes. Analysis of proteins of high molecular mass, and of cyclic and acyclic oligosaccharides. |
PubMed:Changes in acid-base equilibria of harmine and harmane inclusion complexes with cyclodextrins. |
PubMed:Evaluation of African medicinal plants for their in vitro trypanocidal activity. |
PubMed:Inhibition of monoamine oxidase from bovine retina by beta-carbolines. |
PubMed:Effects of harmane (1-methyl-beta-carboline) on neurons in the nucleus accumbens of the rat. |
PubMed:Locomotor effects in sheep of alkaloids identified in Australian Tribulus terrestris. |
PubMed:Effects of harmane on growth and in vivo metabolism of aflatoxin B1 in male and female rats. |
PubMed:Antioxidative properties of harmane and beta-carboline alkaloids. |
PubMed:[Phenolic constituents of licorice. IV. Correlation of phenolic constituents and licorice specimens from various sources, and inhibitory effects of licorice extracts on xanthine oxidase and monoamine oxidase]. |
PubMed:Effect of beta-carboline derivatives on the binding of L-tryptophan and diazepam to bovine and human albumin. |
PubMed:[The correlation of the serotonin-positive and anxiolytic activities of nonbenzodiazepine substances]. |
PubMed:Upper motor neurone effects in sheep of some beta-carboline alkaloids identified in zygophyllaceous plants. |
PubMed:Bleomycin-treated DNA is specifically cleaved only by endonuclease IV in E. coli. |
PubMed:Synthesis and characterization of novel biologically active platinum(II) and palladium(II) complexes of some beta-carboline alkaloids. |
PubMed:Determination of pharmacological levels of harmane, harmine and harmaline in mammalian brain tissue, cerebrospinal fluid and plasma by high-performance liquid chromatography with fluorimetric detection. |
PubMed:[Tryptamine as an endogenous modulator of neuronal sensitivity to serotonin]. |
PubMed:Beta-carbolines as antagonists of the discriminative stimulus effects of diazepam in rats. |
PubMed:Acetaldehyde and its condensation products as markers in alcoholism. |
PubMed:Benzodiazepine receptors are involved in tabernanthine-induced tremor: in vitro and in vivo evidence. |
PubMed:[Characteristics of the presynaptic action of harman and its derivatives compared to benzodiazepine tranquilizers]. |
PubMed:[Photosensitized generation of singlet molecular oxygen by endogenous substances of the eye lens]. |
PubMed:Inhibition of calcium channels by harmaline and other harmala alkaloids in vascular and intestinal smooth muscles. |
PubMed:Interaction of carbolines and some GABA receptor ligands with the GABA and the benzodiazepine receptors. |
PubMed:[Prolonged administration of antidepressants induces changes in the pulsed release but not in the reverse uptake of biogenic amines]. |
PubMed:[GABA-ergic effects of harman independent of its influence on benzodiazepine receptors]. |
PubMed:[Ion-dependency of the GABA-potentiating effects of benzodiazepine tranquilizers and harmane]. |
PubMed:Effects of betacarbolines on the automaticity of the guinea pig sinus node. |
PubMed:Actions of 6-aminonicotinamide on benzodiazepine receptors in rat CNS. |
PubMed:New endogenous benzodiazepine receptor ligand in human urine: identity with endogenous monoamine oxidase inhibitor? |
PubMed:In vitro studies on the effect of beta-carbolines on the activities of acetylcholinesterase and choline acetyltransferase and on the muscarinic receptor binding of the rat brain. |
PubMed:UV-mediated genotoxicity of furanoquinoline and of certain tryptophan-derived alkaloids. |
PubMed:Tofizopam enhances the action of diazepam against tremor and convulsions. |
PubMed:Stereoisomeric tetrahydro-beta-carbolines differ in their interaction with rat brain benzodiazepine receptors. |
PubMed:[Harman and 3-methylharman--blockaders of presynaptic alpha 2-adrenoreceptors]. |
PubMed:Binding of beta-carbolines and caffeine on benzodiazepine receptors: correlations to convulsions and tremor. |
PubMed:[Characteristics of GABA-potentiating effect of harman]. |
PubMed:beta-Carbolines as selective monoamine oxidase inhibitors: in vivo implications. |
PubMed:Effects of harmala alkaloids on transmembrane potentials of guinea-pig papillary muscles. |
PubMed:Is there a correlation between the concentration of beta-carbolines and their pharmacodynamic effects? |
PubMed:Selective inhibition by harmane of the apurinic apyrimidinic endonuclease activity of phage T4-induced UV endonuclease. |
PubMed:beta-Carboline binding to deoxycholate solubilized benzodiazepine receptors from calf cerebral cortex. |
PubMed:Role of brain monoamine systems in the jumping behavior induced in rats by the combination of harmine and apomorphine. |
PubMed:On the neuropharmacology of harmane and other beta-carbolines. |
PubMed:Benzodiazepine antagonism by harmane and other beta-carbolines in vitro and in vivo. |
PubMed:Affinity of beta-carbolines on rat brain benzodiazepine and opiate binding sites. |
PubMed:1-Methyl-beta-carboline (harmane), a potent endogenous inhibitor of benzodiazepine receptor binding. |
PubMed:Excretion of tetrahydroharmane and harmane into the urine of man and rat after a load with ethanol. |
PubMed:[Quantitative determination of harmane and harmine in the extract of Passiflora incarnata]. |
PubMed:[Relations between the structure of synthetic harmane derivatives and their antiserotonin, MAO-paralyzing, and anti-coronary, blocking effects. I]. |