glyoxylic acid
oxoacetic acid
Found in plant and animal tissues. Prod. by Aspergillus niger and other microorganisms (CCD) Glyoxylic acid or oxoacetic acid is a colourless solid that occurs naturally and is useful industrially. (Wikipedia)
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      G0366 Glyoxylic Acid (ca. 50% in Water, ca. 9mol/L)
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oxaldehydic acid (Click)
CAS Number: 298-12-4Picture of molecule
Other: 872051-56-4
ECHA EINECS - REACH Pre-Reg: 206-058-5
Nikkaji Web: J38.150K
Beilstein Number: 0741891
MDL: MFCD00006958
XlogP3-AA: -0.30 (est)
Molecular Weight: 74.03554000
Formula: C2 H2 O3
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: buffering agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
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PubMed: Search
NCBI: Search
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Physical Properties:
Appearance: white crystals (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 1.34200 @  25.00 °C.
Refractive Index: 1.41490 @  20.00 °C.
Melting Point: 98.00 °C. @ 760.00 mm Hg
Boiling Point: 224.60 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 1.060000 mm/Hg @ 25.00 °C.
Flash Point: 219.00 °F. TCC ( 103.90 °C. ) (est)
logP (o/w): -0.930 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
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Organoleptic Properties:
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: buffering agents
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Connect Chemicals
Glyoxylic acid
Odor: characteristic
Use: Glyoxylic Acid (GXA) is a colorless solid and a highly reactive chemical intermediate having two functional groups: an aldehyde group and a carboxylic acid group. Glyoxylic Acid is soluble in water and ethanol, slightly soluble in organic solvents like ether or benzene, and insoluble in esters aromatic solvents. Aqueous solutions of Glyoxylic Acid are transparent, colorless or light yellow liquids.
Covalent Chemical
Glyoxylic Acid
Santa Cruz Biotechnology
For experimental / research use only.
Glyoxylic acid solution
Sigma-Aldrich: Aldrich
For experimental / research use only.
Glyoxylic acid solution 50 wt. % in H2O
For experimental / research use only.
Glyoxylic Acid (ca. 50% in Water, ca. 9mol/L)
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Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intramuscular-rat LDLo  250 mg/kg
Bolletino della Societe Italiana di Biologia Sperimentale. Vol. 36, Pg. 1937, 1960.

oral-rat LDLo  3000 mg/kg
American Journal of Clinical Pathology. Vol. 45, Pg. 46, 1966.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: buffering agents
Recommendation for glyoxylic acid usage levels up to:
 not for fragrance use.
Recommendation for glyoxylic acid flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
NLM Hazardous Substances Data Bank: Search
Chemical Carcinogenesis Research Information System: Search
Cancer Citations: Search
Toxicology Citations: Search
Env. Mutagen Info. Center: Search
EPA Substance Registry Services (TSCA): 298-12-4
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 760
National Institute of Allergy and Infectious Diseases: Data
WISER: UN 3265
WGK Germany: 1
 oxaldehydic acid
Chemidplus: 0000298124
EPA/NOAA CAMEO: hazardous materials
RTECS: MD4550000 for cas# 298-12-4
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 oxaldehydic acid
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 298-12-4
Pubchem (cid): 760
Pubchem (sid): 134974802
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
Golm Metabolome Database: Search
Metabolomics Database: Search
UM BBD: Search
KEGG (GenomeNet): C00048
HMDB (The Human Metabolome Database): HMDB00119
FooDB: FDB001478
YMDB (Yeast Metabolome Database): YMDB00033
Export Tariff Code: 2918.30.9000
Haz-Map: View
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
supplied as a 50% soln .
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Potential Blenders and core components note
None Found
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Potential Uses:
 buffering agents 
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Occurrence (nature, food, other): note
 apple plant
Search Trop  Picture
 banana leaf
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 beet root
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 beet sprout
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Search Trop  Picture
 fig fruit
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 gooseberry fruit
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 not found in nature
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 potato plant
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 tamarind flower
Search Trop  Picture
 tamarind fruit
Search Trop  Picture
 tamarind leaf
Search Trop  Picture
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a-ketoacetic acid
oxoacetic acid
oxo-acetic acid
 acetic acid, 2-oxo-
 acetic acid, oxo- (9CI)
oxoethanoic acid
 formic acid, formyl
 formylformic acid
 glyoxalic acid
 glyoxyl acid
 glyoxylic acid (8CI)
 oxalaldehydic acid
 oxaldehydic acid
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