EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes


Supplier Sponsors

CAS Number: 548-83-4Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:208-960-4
Nikkaji Web:J1.607A
Beilstein Number:0272179
XlogP3:2.30 (est)
Molecular Weight:270.24070000
Formula:C15 H10 O5
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 214.50 °C. @ 760.00 mm Hg
Boiling Point: 518.64 °C. @ 760.00 mm Hg (est)
Flash Point: 396.00 °F. TCC ( 202.00 °C. ) (est)
logP (o/w): 3.322 (est)
Soluble in:
 water, 571.9 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
Alfa Biotechnology
For experimental / research use only.
Galangin 98%
BOC Sciences
For experimental / research use only.
Odor: characteristic
Use: Galangin isolated from the rhizome of Zingiber officinale Roscoe. It can inhibit Topo I activity and reduce the unwinding rate of single stranded DNNA in tumor cells, which plays an important role in induction of A549 and H46 cell apoptosis. antibacterial; antimicrobial; tyrosinase inhibitor; antioxidant; antiviral;
Changsha Organic Herb
Galangal Root extract
For experimental / research use only.
Galangin (HPLC) ≥99%
Santa Cruz Biotechnology
For experimental / research use only.
Galangin ≥98%
Sigma-Aldrich: Sigma
For experimental / research use only.
autophagy inducing flavonoid
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-mouse LD > 1500 mg/kg
Dokl Akad Nauk resp. Uzb.Vol. (9-10), Pg. 55, 1995.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
natural substances and extractives
Recommendation for galangin usage levels up to:
 not for fragrance use.
Recommendation for galangin flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5281616
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
RTECS:LK9275500 for cas# 548-83-4
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5281616
Pubchem (sid):134978005
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C10044
HMDB (The Human Metabolome Database):HMDB29521
Export Tariff Code:2932.90.4100
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 galangal lesser galangal root
Search Trop Picture
4H-1-benzopyran-4-one, 3,5, 7-trihydroxy-2-phenyl-
4H-1-benzopyran-4-one, 3,5,7-trihydroxy-2-phenyl-
 flavone, 3,5,7-trihydroxy-


PubMed:Identification of luteolin as enterovirus 71 and coxsackievirus A16 inhibitors through reporter viruses and cell viability-based screening.
PubMed:[Flavonoids from the seeds of Alpinia galanga Willd].
PubMed:Simultaneous determination of eight flavonoids in propolis using chemometrics-assisted high performance liquid chromatography-diode array detection.
PubMed:Development of high-performance liquid chromatographic for quality and authenticity control of chinese propolis.
PubMed:Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux.
PubMed:Synthesis and anticancer activity of new flavonoid analogs and inconsistencies in assays related to proliferation and viability measurements.
PubMed:The Effects of Galangin on a Mouse Model of Vitiligo Induced by Hydroquinone.
PubMed:Flavonols modulate the effector functions of healthy individuals' immune complex-stimulated neutrophils: a therapeutic perspective for rheumatoid arthritis.
PubMed:Galangin Dampens Mice Lipopolysaccharide-Induced Acute Lung Injury.
PubMed:In-vitro anti-proliferative and anti-oxidant activity of galangin, fisetin and quercetin: role of localization and intermolecular interaction in model membrane.
PubMed:In vivo evolution of metabolic pathways by homeologous recombination in mitotic cells.
PubMed:Inhibitory effect of galangin on atopic dermatitis-like skin lesions.
PubMed:Differences in the hydroxylation pattern of flavonoids alter their chemoprotective effect against direct- and indirect-acting mutagens.
PubMed:Identification of quercitrin as a potential therapeutic agent for periodontal applications.
PubMed:Effect of edible oils on quercetin, kaempferol and galangin transport and conjugation in the intestinal Caco-2/HT29-MTX co-culture model.
PubMed:Structure-activity relationship studies of flavonol analogues on pollen germination.
PubMed:Galangin, a dietary flavonol inhibits tumor initiation during experimental pulmonary tumorigenesis by modulating xenobiotic enzymes and antioxidant status.
PubMed:Allantoinase and dihydroorotase binding and inhibition by flavonols and the substrates of cyclic amidohydrolases.
PubMed:Related flavonoids cause cooperative inhibition of the sarcoplasmic reticulum Ca²⁺ ATPase by multimode mechanisms.
PubMed:Galangin inhibits proliferation of hepatocellular carcinoma cells by inducing endoplasmic reticulum stress.
PubMed:Evaluation of estrogenic potential of flavonoids using a recombinant yeast strain and MCF7/BUS cell proliferation assay.
PubMed:Quercitrin and taxifolin stimulate osteoblast differentiation in MC3T3-E1 cells and inhibit osteoclastogenesis in RAW 264.7 cells.
PubMed:Prediction of comparative inhibition efficiency for a novel natural ligand, galangin against human brain acetylcholinesterase, butyrylcholinesterase and 5-lipoxygenase: a neuroinformatics study.
PubMed:Current acetylcholinesterase-inhibitors: a neuroinformatics perspective.
PubMed:Trans-chalcone and quercetin down-regulate fatty acid synthase gene expression and reduce ergosterol content in the human pathogenic dermatophyte Trichophyton rubrum.
PubMed:Galangin inhibits proliferation of HepG2 cells by activating AMPK via increasing the AMP/TAN ratio in a LKB1-independent manner.
PubMed:Suitability of antioxidant capacity, flavonoids and phenolic acids for floral authentication of honey. Impact of industrial thermal treatment.
PubMed:AβPP-selective BACE inhibitors (ASBI): novel class of therapeutic agents for alzheimer's disease.
PubMed:Application of visible and near infrared spectroscopy for rapid analysis of chrysin and galangin in Chinese propolis.
PubMed:[Chemical constituents in Thunbergia from Africa].
PubMed:Galangin induces human colon cancer cell death via the mitochondrial dysfunction and caspase-dependent pathway.
PubMed:Indirect activation of the SV23 and SV24 splice variants of human constitutive androstane receptor: analysis with 3-hydroxyflavone and its analogues.
PubMed:Analysis of serum metabolites for the discovery of amino acid biomarkers and the effect of galangin on cerebral ischemia.
PubMed:Galangin Abrogates Ovalbumin-Induced Airway Inflammation via Negative Regulation of NF-κB.
PubMed:Antifibrotic activity of galangin, a novel function evaluated in animal liver fibrosis model.
PubMed:Chemical and functional characterisation of propolis collected from East Andalusia (southern Spain).
PubMed:Chemical composition of two different extracts of berries harvested in Serbia.
PubMed:Flavonols enhanced production of anti-inflammatory substance(s) by Bifidobacterium adolescentis: prebiotic actions of galangin, quercetin, and fisetin.
PubMed:Galangin attenuates mast cell-mediated allergic inflammation.
PubMed:Chemical composition, cytotoxic and antioxidative activities of ethanolic extracts of propolis on HCT-116 cell line.
PubMed:Binding of diverse environmental chemicals with human cytochromes P450 2A13, 2A6, and 1B1 and enzyme inhibition.
PubMed:Molecular mechanisms underlying the in vitro anti-inflammatory effects of a flavonoid-rich ethanol extract from chinese propolis (poplar type).
PubMed:Anti-obesity effects of galangin, a pancreatic lipase inhibitor in cafeteria diet fed female rats.
PubMed:Antibacterial activity of Sonoran propolis and some of its constituents against clinically significant Vibrio species.
PubMed:The determination of phenolic profiles of Serbian unifloral honeys using ultra-high-performance liquid chromatography/high resolution accurate mass spectrometry.
PubMed:Identification and quantification of phytochemical composition and anti-inflammatory and radical scavenging properties of methanolic extracts of Chinese propolis.
PubMed:In search of new biological activities of isolates from Odontoglossum Harvengtense 'Tutu'.
PubMed:By improving regional cortical blood flow, attenuating mitochondrial dysfunction and sequential apoptosis galangin acts as a potential neuroprotective agent after acute ischemic stroke.
PubMed:Alpinia officinarum inhibits adipocyte differentiation and high-fat diet-induced obesity in mice through regulation of adipogenesis and lipogenesis.
PubMed:Galangin and its emerging anti-neoplastic effects.
PubMed:Characterization of flavonol inhibition of DnaB helicase: real-time monitoring, structural modeling, and proposed mechanism.
PubMed:Galangin induces B16F10 melanoma cell apoptosis via mitochondrial pathway and sustained activation of p38 MAPK.
PubMed:The natural flavonoid galangin inhibits osteoclastic bone destruction and osteoclastogenesis by suppressing NF-κB in collagen-induced arthritis and bone marrow-derived macrophages.
PubMed:In vivo investigation on the potential of galangin, kaempferol and myricetin for protection of D-galactose-induced cognitive impairment.
PubMed:Influence of oxidative stress on inducing micturition dysfunction following chronic infravesical obstruction and the protective role of an antioxidant diet - association of in vivo and in vitro studies in rats.
PubMed:Potential of fruit wastes as natural resources of bioactive compounds.
PubMed:Antioxidant capacity of flavonoids in hepatic microsomes is not reflected by antioxidant effects in vivo.
PubMed:Anticomplement and antimicrobial activities of flavonoids from Entada phaseoloides.
PubMed:Galangin inhibits tumor growth and metastasis of B16F10 melanoma.
PubMed:The photodegradation of quercetin: relation to oxidation.
PubMed:Influence of dietary flavonoids on the glycation of plasma proteins.
PubMed:Correlation between mammalian cell cytotoxicity of flavonoids and the redox potential of phenoxyl radical/phenol couple.
PubMed:Flavonoid aglycones can compete with Ochratoxin A for human serum albumin: a new possible mode of action.
PubMed:Galangin induces apoptosis in hepatocellular carcinoma cells through the caspase 8/t-Bid mitochondrial pathway.
PubMed:Mutagenicity of flavonoids assayed by bacterial reverse mutation (Ames) test.
PubMed:Inhibitory activity of liposomal flavonoids during oxidative metabolism of human neutrophils upon stimulation with immune complexes and phorbol ester.
PubMed:Galangin induces autophagy through upregulation of p53 in HepG2 cells.
PubMed:SERS spectroscopy of kaempferol and galangin under the interaction of human serum albumin with adsorbed silver nanoparticles.
PubMed:The bioflavonoid galangin suppresses the growth of ehrlich ascites carcinoma in Swiss Albino mice: a molecular insight.
PubMed:Small molecule inhibitors of the HPV16-E6 interaction with caspase 8.
PubMed:Induction of oxidative DNA damage by flavonoids of propolis: its mechanism and implication about antioxidant capacity.
PubMed:Galangin induces apoptosis in gastric cancer cells via regulation of ubiquitin carboxy-terminal hydrolase isozyme L1 and glutathione S-transferase P.
PubMed:[Composition, antifungal and radical scavenging activities of 4 propolis].
PubMed:Synergistic activity and mode of action of flavonoids isolated from smaller galangal and amoxicillin combinations against amoxicillin-resistant Escherichia coli.
PubMed:Current pharmacological and phytochemical studies of the plant Alpinia galanga.
PubMed:Structure of flavonoids influences the degree inhibition of Benzo(a)pyrene - induced DNA damage and micronuclei in HepG2 cells.
PubMed:¹H-NMR simultaneous identification of health-relevant compounds in propolis extracts.
PubMed:Galanin and the orexin 2 receptor as possible regulators of enkephalin in the paraventricular nucleus of the hypothalamus: relation to dietary fat.
PubMed:Polyphenolic fraction of Algerian propolis protects rat kidney against acute oxidative stress induced by doxorubicin.
PubMed:Effect of galangin supplementation on oxidative damage and inflammatory changes in fructose-fed rat liver.
PubMed:The flavonoid scaffold as a template for the design of modulators of the vascular Ca(v) 1.2 channels.
PubMed:In vitro evaluation of the antioxidant activity of liposomal flavonols by the HRP-H2O2-luminol system.
PubMed:Chemical composition of the ethanolic propolis extracts and its effect on HeLa cells.
PubMed:Selective determination of human immunoglobulin G by flow-injection chemiluminescence.
PubMed:Effect of traditional Chinese medicinal herbs on Candida spp. from patients with HIV/AIDS.
PubMed:Galangin suppresses the proliferation of β-catenin response transcription-positive cancer cells by promoting adenomatous polyposis coli/Axin/glycogen synthase kinase-3β-independent β-catenin degradation.
PubMed:Analysis of flavonoids in honey by HPLC coupled with coulometric electrode array detection and electrospray ionization mass spectrometry.
PubMed:Inhibition of Klebsiella pneumoniae DnaB helicase by the flavonol galangin.
PubMed:Bioactivity guided isolation of anticancer constituents from leaves of Alnus sieboldiana (Betulaceae).
PubMed:Dose-dependent effect of galangin on fructose-mediated insulin resistance and oxidative events in rat kidney.
PubMed:Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives.
PubMed:Antileishmanial phenylpropanoids from Alpinia galanga (Linn.) Willd.
PubMed:Reversing β-lactam antibiotic resistance of Staphylococcus aureus with galangin from Alpinia officinarum Hance and synergism with ceftazidime.
PubMed:Potent modification of inducible CYP1A1 expression by flavonoids.
PubMed:3-O-arylmethylgalangin, a novel isostere for anti-HCV 1,3-diketoacids (DKAs).
PubMed:Differential mechanisms for the inhibition of human cytochrome P450 1A2 by apigenin and genistein.
PubMed:7-O-Arylmethylgalangin as a novel scaffold for anti-HCV agents.
PubMed:Relationships between structures of hydroxyflavones and their antioxidative effects.
PubMed:Galangin induces apoptosis of hepatocellular carcinoma cells via the mitochondrial pathway.
PubMed:Metabolites of galangin by 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P450 1A1 in human intestinal epithelial Caco-2 cells and their antagonistic activity toward aryl hydrocarbon receptor.
PubMed:Galangin, a flavonol derived from Rhizoma Alpiniae Officinarum, inhibits acetylcholinesterase activity in vitro.
PubMed:Generalized concentration addition predicts joint effects of aryl hydrocarbon receptor agonists with partial agonists and competitive antagonists.
PubMed:In vitro modulation of naturally occurring flavonoids on cytochrome P450 2A6 (CYP2A6) activity.
PubMed:Dietary bioflavonoids inhibit Escherichia coli ATP synthase in a differential manner.
PubMed:Study on the constituents of Mexican propolis and their cytotoxic activity against PANC-1 human pancreatic cancer cells.
PubMed:Flavonoids inhibit hypoxia-induced vascular endothelial growth factor expression by a HIF-1 independent mechanism.
PubMed:Absorption, Conjugation and Efflux of the Flavonoids, Kaempferol and Galangin, Using the Intestinal CACO-2/TC7 Cell Model.
PubMed:Influence of the target molecule on the oxygen radical absorbance capacity index: a comparison between alizarin red- and fluorescein-based methodologies.
PubMed:Effect of seasonal variations and collection form on antioxidant activity of propolis from San Juan, Argentina.
PubMed:The potential role of honey and its polyphenols in preventing heart diseases: a review.
PubMed:Biogenic synthesis of Au and Ag nanoparticles by Indian propolis and its constituents.
PubMed:Effect of Zinc (II) on the interactions of bovine serum albumin with flavonols bearing different number of hydroxyl substituent on B-ring.
PubMed:Argentinean propolis from Zuccagnia punctata Cav. (Caesalpinieae) exudates: phytochemical characterization and antifungal activity.
PubMed:Ethanolic Extract of Propolis Augments TRAIL-Induced Apoptotic Death in Prostate Cancer Cells.
PubMed:Structural aspects of flavonoids as inhibitors of human butyrylcholinesterase.
PubMed:Antimicrobial activity of two propolis samples against human Campylobacter jejuni.
PubMed:Two new sesquiterpene glucosides from Dennstaedtia scabra (Wall.) Moore.
PubMed:Bioactivity of flavonoids isolated from Lychnophora markgravii against Leishmania amazonensis amastigotes.
PubMed:Antiproliferative effects of honey and of its polyphenols: a review.
PubMed:Simultaneous quantification of eight major bioactive phenolic compounds in Chinese propolis by high-performance liquid chromatography.
PubMed:Melanogenesis inhibitors from the rhizomes of Alpinia officinarum in B16 melanoma cells.
PubMed:Subcellular localization of flavonol aglycone in hepatocytes visualized by confocal laser scanning fluorescence microscope.
PubMed:Antiviral activity and mode of action of propolis extracts and selected compounds.
PubMed:Flavonoid-induced morphological modifications of endothelial cells through microtubule stabilization.
PubMed:Main flavonoids, DPPH activity, and metal content allow determination of the geographical origin of propolis from the Province of San Juan (Argentina).
PubMed:Regulation of the Bacillus subtilis divergent yetL and yetM genes by a transcriptional repressor, YetL, in response to flavonoids.
PubMed:Acidity of hydroxyl groups: an overlooked influence on antiradical properties of flavonoids.
PubMed:Antioxidant effects of flavonoid from Croatian Cystus incanus L. rich bee pollen.
PubMed:[Study on apoptosis of BEL-7402 cells induced by galangin].
PubMed:Mechanism of CYP2C9 inhibition by flavones and flavonols.
PubMed:Correlation between antiangiogenic activity and antioxidant activity of various components from propolis.
PubMed:Determination of rutin and other flavonoids by flow-injection/adsorptive stripping voltammetry using nujol-graphite and diphenylether-graphite paste electrodes.
PubMed:Polyphenol contents and antioxidant activities of five Indigofera species (Fabaceae) from Burkina Faso.
PubMed:Protective effects of Chinese propolis and its component, chrysin, against neuronal cell death via inhibition of mitochondrial apoptosis pathway in SH-SY5Y cells.
PubMed:Antioxidant activity of flavonoids in isolated mitochondria.
PubMed:Synergistic effects of the combination of galangin with gentamicin against methicillin-resistant Staphylococcus aureus.
PubMed:Inhibition of peroxide-induced radical generation by plant polyphenols in C6 astroglioma cells.
PubMed:Galangin increases the cytotoxic activity of imatinib mesylate in imatinib-sensitive and imatinib-resistant Bcr-Abl expressing leukemia cells.
PubMed:Influence of B-ring hydroxylation on interactions of flavonols with bovine serum albumin.
PubMed:Complexation of flavonoids with iron: structure and optical signatures.
PubMed:[Effects of flavonoids with different structures on proliferation of leukemia cell line HL-60].
PubMed:Evaluation of propolis polyphenols absorption in humans by liquid chromatography/tandem mass spectrometry.
PubMed:Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1alpha/2alpha is mediated through chelation of iron.
PubMed:Aggregation of Staphylococcus aureus following treatment with the antibacterial flavonol galangin.
PubMed:Sonoran propolis: chemical composition and antiproliferative activity on cancer cell lines.
PubMed:Analysis of the polyphenolic fraction of propolis from different sources by liquid chromatography-tandem mass spectrometry.
PubMed:Evaluation of antioxidative activity of Croatian propolis samples using DPPH* and ABTS*+ stable free radical assays.
PubMed:Studies on the interactions between some flavonols and cyclodextrins.
PubMed:Mechanism and inhibitory effect of galangin and its flavonoid mixture from Alpinia officinarum on mushroom tyrosinase and B16 murine melanoma cells.
PubMed:[Quantitative analysis of galangin from propolis in different areas by HPLC].
PubMed:Elastase release by stimulated neutrophils inhibited by flavonoids: importance of the catechol group.
PubMed:Mechanism of inhibition of human secretory phospholipase A2 by flavonoids: rationale for lead design.
PubMed:Identification and quantification of flavonoids of Mexican oregano (Lippia graveolens) by LC-DAD-ESI/MS analysis.
PubMed:Determination of flavonoid aglycones in several food samples by mixed micellar electrokinetic chromatography.
PubMed:Optimisation of an extraction procedure and chemical characterisation of Croatian propolis tinctures.
PubMed:Neutrophil effector functions triggered by Fc-gamma and/or complement receptors are dependent on B-ring hydroxylation pattern and physicochemical properties of flavonols.
PubMed:Dual regulation of the Bacillus subtilis regulon comprising the lmrAB and yxaGH operons and yxaF gene by two transcriptional repressors, LmrA and YxaF, in response to flavonoids.
PubMed:Esterase inhibition by grapefruit juice flavonoids leading to a new drug interaction.
PubMed:Inhibition of horseradish peroxidase catalytic activity by new 3-phenylcoumarin derivatives: synthesis and structure-activity relationships.
PubMed:TCDD-induced CYP1A1 expression, an index of dioxin toxicity, is suppressed by flavonoids permeating the human intestinal Caco-2 cell monolayers.
PubMed:Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.
PubMed:Methylation protects dietary flavonoids from rapid hepatic metabolism.
PubMed:Propolis from the northwest of Argentina as a source of antifungal principles.
PubMed:Flavonoids protect human retinal pigment epithelial cells from oxidative-stress-induced death.
PubMed:The effect of quercetin and galangin on glutathione reductase.
PubMed:Growth of a human mammary tumor cell line is blocked by galangin, a naturally occurring bioflavonoid, and is accompanied by down-regulation of cyclins D3, E, and A.
PubMed:Inhibition of rat vas deferens contractions by flavonoids in-vitro.
PubMed:Assessment of the antibacterial activity of galangin against 4-quinolone resistant strains of Staphylococcus aureus.
PubMed:Influence of galangin on HL-60 cell proliferation and survival.
PubMed:Galangin protects pig detrusor nerves from repetitive field stimulation and anoxia/glucopenia injury.
PubMed:Antiherpetic activities of flavonoids against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) in vitro.
PubMed:Antimicrobial activity of flavonoids.
PubMed:Use of the pig caecum model to mimic the human intestinal metabolism of hispidulin and related compounds.
PubMed:Dietary flavonoids: effects on xenobiotic and carcinogen metabolism.
PubMed:The inhibitory effect of the flavonoid galangin on urinary bladder smooth muscle contractility is mediated in part by modulation of Ca2+ release from intracellular stores.
PubMed:Inhibitors from the rhizomes of Alpinia officinarum on production of nitric oxide in lipopolysaccharide-activated macrophages and the structural requirements of diarylheptanoids for the activity.
PubMed:Chemical structure of flavonols in relation to modulation of angiogenesis and immune-endothelial cell adhesion.
PubMed:Vasorelaxant effect of the flavonoid galangin on isolated rat thoracic aorta.
PubMed:Combinatorial biosynthesis of flavones and flavonols in Escherichia coli.
PubMed:Solanoflavone, a new biflavonol glycoside from Solanum melongena: seeking for anti-inflammatory components.
PubMed:Detection of galangin-induced cytoplasmic membrane damage in Staphylococcus aureus by measuring potassium loss.
PubMed:Production of cytokine and NO by RAW 264.7 macrophages and PBMC in vitro incubation with flavonoids.
PubMed:Multiple-signaling pathways are involved in the inhibitory effects of galangin on urinary bladder contractility.
PubMed:Flavonoid galangin prevents smooth muscle fatigue of pig urinary bladder.
PubMed:Synthesis, spectral and electrochemical properties of Al(III) and Zn(II) complexes with flavonoids.
PubMed:The interaction of flavonoids with mitochondria: effects on energetic processes.
PubMed:[Xanthine oxidase inhibitory activity and hypouricemia effect of propolis in rats].
PubMed:Flavonoids and tyrosine nitration: structure-activity relationship correlation with enthalpy of formation.
PubMed:Flavonoids induce apoptosis in human leukemia U937 cells through caspase- and caspase-calpain-dependent pathways.
PubMed:Galangin expresses bactericidal activity against multiple-resistant bacteria: MRSA, Enterococcus spp. and Pseudomonas aeruginosa.
PubMed:Inhibitory effect of flavonoids on N-acetylation of 5-aminosalicylic acid in cultured rat hepatocytes.
PubMed:Validated methods for the quantification of biologically active constituents of poplar-type propolis.
PubMed:Antioxidant properties of complexes of flavonoids with metal ions.
PubMed:Effect of flavonoids and vitamin E on cyclooxygenase-2 (COX-2) transcription.
PubMed:Separation of flavonoids and phenolic acids from propolis by capillary zone electrophoresis.
PubMed:The thiol reactivity of the oxidation product of 3,5,7-trihydroxy-4H-chromen-4-one containing flavonoids.
PubMed:Identification of metabolites in plasma and urine of Uruguayan propolis-treated rats.
PubMed:Inhibitory effect of flavonoids on sulfo- and glucurono-conjugation of acetaminophen in rat cultured hepatocytes and liver subcellular preparations.
PubMed:Herbal modulation of P-glycoprotein.
PubMed:Determination of flavonoids by high-performance liquid chromatography and capillary electrophoresis.
PubMed:Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells.
PubMed:Effects of ethanol extract of propolis (EEP) and its flavones on inducible gene expression in J774A.1 macrophages.
PubMed:Analysis of propolis from the continental and Adriatic regions of Croatia.
PubMed:Assessment of the antibacterial activity of selected flavonoids and consideration of discrepancies between previous reports.
PubMed:Effects of flavonoids on glutathione and glutathione-related enzymes in cisplatin-treated L1210 leukemia cells.
PubMed:Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context.
PubMed:Presence of fatty acid synthase inhibitors in the rhizome of Alpinia officinarum hance.
PubMed:Trypanocidal activity of Lychnophora staavioides Mart. (Vernonieae, Asteraceae).
PubMed:Reduction of genistein clastogenicity in Chinese hamster V79 cells by daidzein and other flavonoids.
PubMed:Inhibitory effects of some flavonoids on the activity of mushroom tyrosinase.
PubMed:Inhibitory effect of the plant flavonoid galangin on rat vas deferens in vitro.
PubMed:Glucuronidation activity of the UGT2B17 enzyme toward xenobiotics.
PubMed:Kinetic and stoichiometric assessment of the antioxidant activity of flavonoids by electron spin resonance spectroscopy.
PubMed:Taxonomic significance of flavonoid variation in temperate species of Nothofagus.
PubMed:Effect of flavone derivatives on interleukin-1beta (IL-1beta) mRNA expression and IL-1beta protein synthesis in stimulated RAW 264.7 macrophages.
PubMed:[Study on the chemical components of Alpinia officinarum].
PubMed:Phytochemical compounds involved in the anti-inflammatory effect of propolis extract.
PubMed:The role of the phenethyl ester of caffeic acid (CAPE) in the inhibition of rat lung cyclooxygenase activity by propolis.
PubMed:Antioxidant activity of propolis: role of caffeic acid phenethyl ester and galangin.
PubMed:Evaluation of the clastogenic, DNA intercalative, and topoisomerase II-interactive properties of bioflavonoids in Chinese hamster V79 cells.
PubMed:Effects of flavonoids on cisplatin-induced apoptosis of HL-60 and L1210 leukemia cells.
PubMed:The inhibitory effect of propolis and caffeic acid phenethyl ester on cyclooxygenase activity in J774 macrophages.
PubMed:[Flavonoids from Beijing propolis].
PubMed:Effect of the flavonoid galangin on urinary bladder rat contractility in-vitro.
PubMed:Protection of flavonoids against lipid peroxidation: the structure activity relationship revisited.
PubMed:Chemical composition of European propolis: expected and unexpected results.
PubMed:2-Methoxyestradiol inhibits proliferation and induces apoptosis independently of estrogen receptors alpha and beta.
PubMed:Rutin-enhanced antibacterial activities of flavonoids against Bacillus cereus and Salmonella enteritidis.
PubMed:Interactions of flavones and other phytochemicals with adenosine receptors.
PubMed:Arginine to lysine 108 substitution in recombinant CYP1A2 abolishes methoxyresorufin metabolism in lymphoblastoid cells.
PubMed:Luteolin, a flavone, does not suppress postprandial glucose absorption through an inhibition of alpha-glucosidase action.
PubMed:Glucuronidation versus oxidation of the flavonoid galangin by human liver microsomes and hepatocytes.
PubMed:The flavonoid galangin inhibits the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia.
PubMed:Oxidation of the flavonoids galangin and kaempferide by human liver microsomes and CYP1A1, CYP1A2, and CYP2C9.
PubMed:Inhibitory effects of naturally occurring compounds on aflatoxin B(1) biotransformation.
PubMed:[Glabrizoflavone--a novel isoflavone from Glycyrrhiza glabra L].
PubMed:Peroxynitrite scavenging of flavonoids: structure activity relationship.
PubMed:Role of lipophilicity and hydrogen peroxide formation in the cytotoxicity of flavonols.
PubMed:Anti-genotoxicity of galangin as a cancer chemopreventive agent candidate.
PubMed:Flavonoids as peroxynitrite scavengers: the role of the hydroxyl groups.
PubMed:Metabolic fate of luteolin and its functional activity at focal site.
PubMed:Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 expression by flavonoids in macrophage J774A.1.
PubMed:Vancomycin resistance reversal in enterococci by flavonoids.
PubMed:B-ring substituted 5,7-dihydroxyflavonols with high-affinity binding to P-glycoprotein responsible for cell multidrug resistance.
PubMed:Flavonols from Heterotheca inuloides: tyrosinase inhibitory activity and structural criteria.
PubMed:In vitro activity of propolis against Streptococcus pyogenes.
PubMed:The bioflavonoid galangin blocks aryl hydrocarbon receptor activation and polycyclic aromatic hydrocarbon-induced pre-B cell apoptosis.
PubMed:Antibacterial and allelopathic activity of extract from Castanea sativa leaves.
PubMed:Prenyl-flavonoids as potent inhibitors of the Pdr5p multidrug ABC transporter from Saccharomyces cerevisiae.
PubMed:Inhibitory effects of flavonoids on rabbit heart carbonyl reductase.
PubMed:Chemical composition and antimicrobial activity of European propolis.
PubMed:Separation of structurally related flavonoids by GC/MS technique and determination of their polarographic parameters and potential carcinogenicity.
PubMed:Flavonols from saffron flower: tyrosinase inhibitory activity and inhibition mechanism.
PubMed:Validation of a liquid chromatography ionspray mass spectrometry method for the analysis of flavanones, flavones and flavonols.
PubMed:Effect of Apis mellifera propolis from two Brazilian regions on caries development in desalivated rats.
PubMed:Structure-activity relationship of cardiotonic flavonoids in guinea-pig papillary muscle.
PubMed:Protective effect of flavonoids on endothelial cells against linoleic acid hydroperoxide-induced toxicity.
PubMed:The flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptor.
PubMed:Structure-activity relationships of flavonoids and the induction of granulocytic- or monocytic-differentiation in HL60 human myeloid leukemia cells.
PubMed:Tannins, flavonol sulfonates, and a norlignan from phyllanthus virgatus
PubMed:Comparative inhibition of human cytochromes P450 1A1 and 1A2 by flavonoids.
PubMed:The effect of flavonoids on ofloxacin-induced mutagenicity in Euglena gracilis.
PubMed:Inhibition of methoxyresorufin demethylase activity by flavonoids in human liver microsomes.
PubMed:Antigenotoxicity of galangin against N-methyl-N-nitrosourea.
PubMed:In vitro biotransformation of flavonoids by rat liver microsomes.
PubMed:Antimicrobial activity of propolis on oral microorganisms.
PubMed:Induction of the anticarcinogenic marker enzyme, quinone reductase, in murine hepatoma cells in vitro by flavonoids.
PubMed:Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study.
PubMed:Metabolism of galangin by rat cytochromes P450: relevance to the genotoxicity of galangin.
PubMed:The antimicrobial activity of 3,5,7-trihydroxyflavone isolated from the shoots of Helichrysum aureonitens.
PubMed:Pharmacological effects of selected flavonoids on rat isolated ileum: structure-activity relationship.
PubMed:Antiviral activity of galangin isolated from the aerial parts of Helichrysum aureonitens.
PubMed:Inhibition of proliferation of estrogen receptor-positive MCF-7 human breast cancer cells by flavonoids in the presence and absence of excess estrogen.
PubMed:Inhibition of neutrophils' chemiluminescence by ethanol extract of propolis (EEP) and its phenolic components.
PubMed:Interaction of organotins with a vacuolar-type H(+)-ATPase.
PubMed:Synthesis and biological activities of flavonoid derivatives as A3 adenosine receptor antagonists.
PubMed:Anticlastogenic effects of galangin against mitomycin C-induced micronuclei in reticulocytes of mice.
PubMed:Interactions of flavonoids and other phytochemicals with adenosine receptors.
PubMed:Flavonoids, potent inhibitors of the human P-form phenolsulfotransferase. Potential role in drug metabolism and chemoprevention.
PubMed:Inhibition of human breast cancer cell proliferation and delay of mammary tumorigenesis by flavonoids and citrus juices.
PubMed:Redox intermediates of flavonoids and caffeic acid esters from propolis: an EPR spectroscopy and cyclic voltammetry study.
PubMed:Effects of flavonols on P-glycoprotein activity in cultured rat hepatocytes.
PubMed:Anticlastogenic effects of galangin against bleomycin-induced chromosomal aberrations in mouse spleen lymphocytes.
PubMed:Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-glycoprotein as a putative mechanism.
PubMed:Chemical composition of North American bee propolis and biological activity towards larvae of greater wax moth (Lepidoptera: Pyralidae).
PubMed:Flavonol-stimulated efflux of 7,12-dimethylbenz(a)anthracene in multidrug-resistant breast cancer cells.
PubMed:Biochemical studies of a new class of alcohol dehydrogenase inhibitors from Radix puerariae.
PubMed:Effects of flavonoids on the release of reactive oxygen species by stimulated human neutrophils. Multivariate analysis of structure-activity relationships (SAR).
PubMed:A method to screen for the antioxidant effect of compounds on low-density lipoprotein (LDL): illustration with flavonoids.
PubMed:Anticlastogenic effect of flavonoids against mutagen-induced micronuclei in mice.
PubMed:Synergistic effect of flavones and flavonols against herpes simplex virus type 1 in cell culture. Comparison with the antiviral activity of propolis.
PubMed:Strand scission in DNA induced by dietary flavonoids: role of Cu(I) and oxygen free radicals and biological consequences of scission.
PubMed:Activities of flavonoids for the cleavage of DNA in the presence of Cu(II): correlation with generation of active oxygen species.
PubMed:In vitro inhibition and stimulation of purified prostaglandin endoperoxide synthase by flavonoids: structure-activity relationship.
PubMed:Inhibitory effects of phenolic compounds on CCl4-induced microsomal lipid peroxidation.
PubMed:Effect of benzopyrone derivatives on simultaneously induced croton oil ear oedema and carrageenin paw oedema in rats.
PubMed:Effects of propolis flavonoids on virus infectivity and replication.
PubMed:Strand scission in DNA induced by quercetin and Cu(II): role of Cu(I) and oxygen free radicals.
PubMed:Flavonoids as antioxidants evaluated by in vitro and in situ liver chemiluminescence.
PubMed:Enhancement of the mutagenicity of 2-acetylaminofluorene by flavonoids and the structural requirements.
PubMed:Flavonoid content in propolis extracts and growth inhibition of Bacillus subtilis.
PubMed:Leaf Gland Flavonoids in Comptonia peregrina and Myrica pensylvanica (Myricaceae).
PubMed:In vivo exposure to plant flavonols. Influence on frequencies of micronuclei in mouse erythrocytes and sister-chromatid exchange in rabbit lymphocytes.
PubMed:Genetic effects of the flavonols quercetin, kaempferol, and galangin on Chinese hamster ovary cells in vitro.
PubMed:Growth inhibition of bacillus subtilis and composition of various propolis extracts.
PubMed:Activation and inhibition of benzo(a)pyrene and aflatoxin B1 metabolism in human liver microsomes by naturally occurring flavonoids.
PubMed:Mutagenicity of plant flavonols in the Salmonella/mammalian microsome test: activation of flavonol glycosides by mixed glycosidases from rat cecal bacteria and other sources.
PubMed:[On the antimicrobial activity of propolis and propolis constituents (author's transl)].
PubMed:Mutagenicity of plant flavonoids: structural requirements for mutagenic activity in Salmonella typhimurium.
Constit. of Galanga root (Alpinia officinarum)
Please share your Comments.
Email Address:
Top of Page Home
Copyright © 1980-2021 The Good Scents Company (tgsc) ™ Disclaimer Privacy Policy