• Azelis
    • Azelis UK Life Sciences
      Chemical Distribution
      Azelis is a leading global distributor of speciality chemicals.
      Azelis is a leading global speciality chemicals distributor. We provide a diverse range of products and innovative services to more than 20,000 customers. Our in-depth local knowledge is supported by an international structure and value-added services including high levels of technical support and tailored solutions.
      Email:Tim Bailey
      Voice:+32 3 613 01 20
      Fax:+32 3 613 01 21
      United Kingdom+44 (0) 1992 82 55 55
      United Kingdom+44 (0) 1992 82 55 66
      Product(s):
      Formaldehyde
       
  • Penta International
    • Penta International Corporation
      Chemistry innovation
      At Penta, our products and services help businesses do business better.
      For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
      US Email:Technical Services
      US Email:Sales
      US Voice:(973) 740-2300
      US Fax:(973) 740-1839
      Product(s):
      FORMALDEHYDE
       
formaldehyde
Notes :
a highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. in solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (from reynolds, martindale the extra pharmacopoeia, 30th ed, p717)
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  • Organoleptics
      • Organoleptic Properties
  • Properties
      • Physical Properties
        Food Chemicals Codex Listed :No
        Specific Gravity :1.08300 @  25.00 °C.
        Boiling Point : -19.50 °C. @ 760.00 mm Hg (est)
        Vapor Pressure :3463.820068 mm/Hg @ 25.00 °C. (est)
        Flash Point : 133.00 °F. TCC ( 56.11 °C. )
        logP (o/w) : 0.350
  • Safety
      • Safety Information
        Oral/Parenteral Toxicity : 
          intravenous-cat LDLo  30 mg/kg
        BLOOD: OTHER CHANGES
        Acta Pharmacologica et Toxicologica. Vol. 8, Pg. 275, 1952.

        intravenous-dog LDLo  70 mg/kg
        International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.

        parenteral-frog LDLo  800 ug/kg
        International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.

        oral-guinea pig LD50  260 mg/kg
        Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.

        unreported-man LDLo  477 mg/kg
        "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.

        oral-man TDLo  643 mg/kg
        GASTROINTESTINAL: NAUSEA OR VOMITING LUNGS, THORAX, OR RESPIRATION: RESPIRATORY OBSTRUCTION GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH
        Japanese Journal of Toxicology. Vol. 4, Pg. 261, 1991.

        oral-man TDLo  646 mg/kg
        GASTROINTESTINAL: NAUSEA OR VOMITING GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: GASTRITIS
        Japanese Journal of Toxicology. Vol. 4, Pg. 261, 1991.

        oral-mouse LD50  42 mg/kg
        BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
        National Technical Information Service. Vol. AD-A125-539

        intraperitoneal-mouse LDLo  16 mg/kg
        Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972.

        intravenous-rabbit LDLo  48 mg/kg
        Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 213, 1955.

        intravenous-rat LD50  87 mg/kg
        Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 221, Pg. 166, 1954.

        oral-rat LD50  100 mg/kg
        Food and Chemical Toxicology. Vol. 26, Pg. 447, 1988.

        Dermal Toxicity : 
          subcutaneous-dog LDLo 350 mg/kg
        International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.

        subcutaneous-mouse LD50 300 mg/kg
        LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
        Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.

        skin-rabbit LD50 270 uL/kg
        Union Carbide Data Sheet. Vol. 4/21/1967

        subcutaneous-rabbit LDLo 240 mg/kg
        JAMA, Journal of the American Medical Association. Vol. 62, Pg. 984, 1914.

        subcutaneous-rat LD50 420 mg/kg
        LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
        Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.

        Inhalation Toxicity : 
          inhalation-cat LCLo 400 mg/m3/2H
        "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 69, 1982.

        inhalation-human TCLo 17 mg/m3/30M
        SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
        JAMA, Journal of the American Medical Association. Vol. 165, Pg. 1908, 1957.

        inhalation-man TCLo 300 ug/m3
        BEHAVIORAL: AGGRESSION SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
        Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 12(7), Pg. 20, 1968.

        inhalation-mouse LC50 454000 mg/m3/4H
        Current Toxicology. Vol. 1, Pg. 47, 1993.

        inhalation-rat LC50 203 mg/m3
        BEHAVIORAL: EXCITEMENT BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE
        Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(2), Pg. 55, 1974.

  • Safety in Use
      • Safety in Use Information
        Category :food-contact surface of paper and paperboard
        NOEL (No Observed Effect Level) :15 (mg/kg bw per day)
        Recommendation for formaldehyde fragrance usage levels up to :
         not for fragrance use.
        Recommendation for formaldehyde flavor usage levels up to :
         not for flavor use.
  • Safety References
      • Safety References
        European Food Safety Authority (EFSA) reference(s) :
        Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20:page or pdf
        Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30:page or pdf
        Report of ESCO WG on non-plastic Food Contact Materials:page or pdf
        Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to use of formaldehyde as a preservative during the manufacture and preparation of food additives:page or pdf
        Reasoned opinion on the modification of the existing MRLs for metaldehyde in certain legume vegetables and pulses:page or pdf
        Scientific Opinion on the re-evaluation of hexamethylene tetramine (E 239) as a food additive:page or pdf
        EPI System :View
        Chemicalize.org :Calculate predicted properties
        IUCLID Chemical Data Sheet :View
        EPA-Iris :IRIS
        ClinicalTrials.gov :search
        Daily Med :search
        NIOSH International Chemical Safety Cards :search
        NIOSH Pocket Guide :search
        NLM Hazardous Substances Data Bank :Search
        Chemical Carcinogenesis Research Information System :Search
        AIDS Citations :Search
        Cancer Citations :Search
        Toxicology Citations :Search
        Carcinogenic Potency Database :Search
        EPA GENetic TOXicology :Search
        NLM Developmental and Reproductive Toxicity :Search
        National Toxicology Program :Search
        EPA Substance Registry Services (TSCA) :50-00-0
        EPA ACToR :Toxicology Data
        EPA ACToR :Toxicology Data
        WGK Germany :2
         formaldehyde
        Chemidplus :0000050000
        EPA/NOAA CAMEO :hazardous materials
        RTECS :50-00-0
  • Articles
      • Articles for the Flavor and Fragrance Industries
        Info :Formaldehyde
  • References
      • References
         formaldehyde
        Canada Domestic Sub. List :50-00-0
        Pubchem (cid):712
        Pubchem (sid):134970847
        Pherobase Floral: View
  • Cosmetics
  • Other
      • Other Information
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        (IUPAC) :Atomic Weights of the Elements 2009
        (IUPAC) :Atomic Weights of the Elements 2009 (pdf)
        Videos :The Periodic Table of Videos
        tgsc :Atomic Weights use for this web site
        (IUPAC) :Periodic Table of the Elements
        FDA Everything Added to Food in the United States (EAFUS) :View
        CHEBI :View
        CHEMBL :View
        Metabolomics Database :Search
        UM BBD :Search
        HMDB (Comprehensive Metabolomic Database) :Search
        Export Tariff Code :2912.11.0000
        Haz-Map : View
        Household Products : Search
        ChemSpider : View
        Wikipedia : View
        RSC Learn Chemistry : View
        Formulations/Preparations :
        •pure formaldehyde is not avail commercially because of its tendency to polymerize. it is sold as aqueous solutions containing from 37% to 50% formaldehyde by wt & varying amounts of methanol. •marketed under the trade name formcel, soln in methanol, n-butanol, and isobutanol. ... •aq formaldehyde, known as formalin, is usually 37% by weight of formaldehyde, though more concn soln are available. formalin is the general-purpose formaldehyde of commerce supplied unstabilized or methanol-stabilized. formaldehyde may also exist in the form of the cyclic trimer trioxane. this is a fairly stable cmpd that does not easily release formaldehyde. ... •grade: aqueous solutions: 37%, 44%, 50% inhibited (with varying percentages of methanol) or stabilized or unstabilized (methanol-free), also available in solution in n-butanol, ethanol, or urea; usp (37% aqueous solution containing methanol). •soluble concentrate; hot fogging concentrate •formaldehyde is available in the united states as as paraformaldehyde. paraformaldehyde is available as a powdered or flaked product that contains the equivalent of 90-93% formaldehyde, a maximum of 9% water, and a maximum of 0.03% acidity as formic acid. it is readily soluble in hot water with the evolution of formaldehyde vapors ... •formalin consists of an aqueous solution of formaldehyde, usually containing about 37% formaldehyde and 12-15% methanol. formalin
  • Blenders
      • Potential Blenders and core components note
        None Found
  • Uses
      • Potential Uses
         preservatives     
  • Occurrence
      • Natural Occurrence in : note
         not found in nature
  • Search
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        Enics, Fema, Flavis
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        Odor
formaldehyde (Click)
CAS Number : 50-00-0
ESIS EC# (EINECS) :200-001-8
Beilstein Number :1209228
XlogP3-AA :1.20 (est)
Molecular Weight :30.02614000
Formula :C H2 O
BioActivity Summary :listing
NMR Predictor :Predict
Category :food-contact surface of paper and paperboard
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information :
Google Scholar : Search Google Books : Search
Google Scholar : with word "volatile"Search Google Scholar : with word "flavor"Search
Google Scholar : with word "odor"SearchPerfumer and Flavorist : Search
Google Patents : Search US Patents : Search
EU Patents : Search IBM Patents : Obtain
Pubchem Patents:Search
PubMed : SearchNCBI : Search
FDA Mainterm : FORMALDEHYDE
FDA Regulation :FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart D--Specific Usage Additives
Sec. 173.340 Defoaming agents.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart B--Substances for Use Only as Components of Adhesives
Sec. 175.105 Adhesives.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.210 Acrylate ester copolymer coating.


FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS
Subpart C--Substances for Use as Components of Coatings
Sec. 175.300 Resinous and polymeric coatings.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.170 Components of paper and paperboard in contact with aqueous and fatty foods.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.180 Components of paper and paperboard in contact with dry food.


FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS
Subpart B--Substances for Use Only as Components of Paper and Paperboard
Sec. 176.200 Defoaming agents used in coatings.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact
Sec. 177.1200 Cellophane.


FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS
Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use
Sec. 177.2410 Phenolic resins in molded articles.


FDA PART 178 -- INDIRECT FOOD ADDITIVES: ADJUVANTS, PRODUCTION AIDS, AND SANITIZERS
Subpart D--Certain Adjuvants and Production Aids
Sec. 178.3120 Animal glue.


FDA PART 573 -- FOOD ADDITIVES PERMITTED IN FEED AND DRINKING WATER OF ANIMALS
Subpart B--Food Additive Listing
Sec. 573.460 Formaldehyde.
click on the picture(s) below to
interact with the 3D model
Picture of molecule
formaldehyde
Synonyms :
 formalin
 formic aldehyde
 formol
 methaldehyde
 methanal
 methyl aldehyde
 paraform
Soluble in :
 water, 400000 mg/L @ 20 °C (exp)
Stability :
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