epichlorohydrin
1-chloro-2,3-epoxypropane

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  CODE124265 CODE124265
  Product(s):
  E0012 epiChlorohydrin >99.0%(GC)
  SDS

CAS Number: 106-89-8 3D/inchi Other(deleted CASRN): 109351-74-8 ECHA EINECS - REACH Pre-Reg: 203-439-8 FDA UNII: 08OOR508C0 Nikkaji Web: J4.037A Beilstein Number: 0079785 MDL: MFCD00005132 XlogP3-AA: 0.50 (est) Molecular Weight: 92.52405000 Formula: C3 H5 Cl O NMR Predictor: Predict (works with chrome, Edge or firefox) Category:indirect food additives: adhesives and components of coatings   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search DG SANTE Food Contact Materials: epichlorohydrin FDA Mainterm (IAUFC): 106-89-8 ; EPICHLOROHYDRIN   Physical Properties: Appearance: colorless to pale yellow clear liquid (est) Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Specific Gravity: 1.18100 to 1.18400 @ 20.00 °C. Pounds per Gallon - (est).: 9.839 to 9.864 Refractive Index: 1.43600 to 1.44000 @ 20.00 °C. Flash Point: 93.00 °F. TCC ( 33.89 °C. ) Soluble in:   water, 6.59E+04 mg/L @ 25 °C (exp)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: None found   Suppliers: Covalent Chemical Epichlorohydrin Shiva Chemicals and Pharmaceuticals Epichlorohydrin Sigma-Aldrich: Aldrich For experimental / research use only. epiChlorohydrin ≥99% sds TCI AMERICA For experimental / research use only. epiChlorohydrin >99.0%(GC) sds   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: intraperitoneal-guinea pig LD50 118 mg/kg Journal of Pharmaceutical Sciences. Vol. 61, Pg. 1712, 1972. oral-guinea pig LD50 280 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(1), Pg. 46, 1968. intraperitoneal-mouse LD50 170 mg/kg Journal of Pharmaceutical Sciences. Vol. 61, Pg. 1712, 1972. oral-mouse LD50 195 mg/kg BEHAVIORAL: ATAXIA BEHAVIORAL: TREMOR BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(1), Pg. 46, 1968. intraperitoneal-rabbit LD50 160 mg/kg Journal of Pharmaceutical Sciences. Vol. 61, Pg. 1712, 1972. oral-rabbit LD50 345 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 33(1), Pg. 46, 1968. intraperitoneal-rat LD50 113 mg/kg Journal of Pharmaceutical Sciences. Vol. 61, Pg. 1712, 1972. intravenous-rat LD50 154 mg/kg Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 41, 1974. oral-rat LD50 90 mg/kg Journal of Industrial Hygiene and Toxicology. Vol. 30, Pg. 63, 1948. Dermal Toxicity: skin-mouse LD50 250 mg/kg "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 64, 1982. subcutaneous-mouse LDLo 250 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" BEHAVIORAL: MUSCLE WEAKNESS Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 2, Pg. 28, 1961. skin-rabbit LD50 515 mg/kg Personal Communication from M.A. Wolf, Dow Chemical Co., Midland, MI 48640, Jan. 18, 1977Vol. 18JAN1977 subcutaneous-rat LD50 150 mg/kg KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED Archives des Maladies Professionnelles de Medecine du Travail et de Securite Sociale. Vol. 28, Pg. 505, 1967. skin-rat LDLo 1000 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES SKIN AND APPENDAGES (SKIN): HAIR: OTHER University of California, Berkeley, Publications in Pharmacology. Vol. 2, Pg. 69, 1941. Inhalation Toxicity: inhalation-human TCLo 20 ppm SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION "Practical Toxicology of Plastics," Lefaux, R., Cleveland, OH, Chemical Rubber Co., 1968Vol. -, Pg. 108, 1968. inhalation-human TCLo 40 ppm/2H LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 240, 1969. inhalation-mouse LCLo 72000 mg/m3/9M Journal of Biomedical Materials Research. Vol. 8, Pg. 11, 1974. inhalation-rat LC50 250 ppm/8H Raw Material Data Handbook, Vol.1: Organic Solvents, 1974. Vol. 1, Pg. 41, 1974.   Safety in Use Information: Category: indirect food additives: adhesives and components of coatings Recommendation for epichlorohydrin usage levels up to:   not for fragrance use.   Recommendation for epichlorohydrin flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View EPA-Iris:IRIS NIOSH International Chemical Safety Cards:search NIOSH Pocket Guide:search Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search Carcinogenic Potency Database:Search EPA GENetic TOXicology:Search EPA Substance Registry Services (TSCA):106-89-8 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :7835 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 2-(chloromethyl)oxirane Chemidplus:0000106898 EPA/NOAA CAMEO:hazardous materials RTECS:106-89-8   References:   2-(chloromethyl)oxirane NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 106-89-8 Pubchem (cid): 7835 Pubchem (sid): 134972083   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Indirect Additives used in Food Contact Substances: View CHEBI: View CHEMBL: View Metabolomics Database: Search KEGG (GenomeNet): C14449 HMDB (The Human Metabolome Database): HMDB34232 FooDB: FDB012543 Export Tariff Code: 2910.30.0000 ChemSpider: View Wikipedia: View   Potential Blenders and core components note None Found   Potential Uses: None Found   Occurrence (nature, food, other):note   not found in nature   Synonyms: 1- chloro-2,3-epoxypropane 2-( chloromethyl)oxirane 1,2- epoxy-3-chloropropane   glycidyl chloride   propane, 1-chloro-2,3-epoxy-   Articles:   None found yet. Try the PubMed Search.

Notes: Used for cross-linking dextrose units in food starch