EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes


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Name:2-amino-3-(4-hydroxyphenyl)propanoic acid
CAS Number: 556-03-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:209-113-1
Nikkaji Web:J598.196D
Beilstein Number:515881
XlogP3:-2.30 (est)
Molecular Weight:181.19127000
Formula:C9 H11 N O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 325.00 °C. @ 760.00 mm Hg
Boiling Point: 385.16 °C. @ 760.00 mm Hg (est)
Flash Point: 368.00 °F. TCC ( 186.70 °C. ) (est)
logP (o/w): -0.418 (est)
Soluble in:
 water, 400 mg/L @ 20 °C (exp)
 water, 9.71e+004 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: antistatic agents
hair conditioning
masking agents
skin conditioning
BOC Sciences
For experimental / research use only.
Glentham Life Sciences
Pangaea Sciences
Tyrosine USP
Penta International
Santa Cruz Biotechnology
For experimental / research use only.
Sigma-Aldrich: Aldrich
For experimental / research use only.
DL-Tyrosine 99%
For experimental / research use only.
DL-Tyrosine >98.0%(HPLC)(T)
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
Category: cosmetic agents
Recommendation for dextro,laevo-tyrosine usage levels up to:
 not for fragrance use.
Recommendation for dextro,laevo-tyrosine flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
Env. Mutagen Info. Center:Search
EPA Substance Registry Services (TSCA):556-03-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :1153
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
2-amino-3-(4-hydroxyphenyl)propanoic acid
 2-amino-3-(4-hydroxyphenyl)propanoic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):1153
Pubchem (sid):135022651
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
Golm Metabolome Database:Search
KEGG (GenomeNet):C01536
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2922.50.4000
RSC Learn Chemistry:View
Potential Blenders and core components note
None Found
Potential Uses:
 antistatic agents
Occurrence (nature, food, other):note
 not found in nature
2-amino-3-(4-hydroxyphenyl)-propanoic acid
2-amino-3-(4-hydroxyphenyl)propanoic acid
2-amino-3-(p-hydroxyphenyl)propionic acid
 tyrosine, DL-


PubMed:Preparation and characterization of a polystyrene/bovine serum albumin nanoparticle-coated capillary for chiral separation using open-tubular capillary electrochromatography.
PubMed:Enantioselective separation of chiral aromatic amino acids with surface functionalized magnetic nanoparticles.
PubMed:Racemic resolution of some DL-amino acids using Aspergillus fumigatus L-amino acid oxidase.
PubMed:Antipsychotic-induced DRD2 upregulation and its prevention by α-lipoic acid in SH-SY5Y neuroblastoma cells.
PubMed:Residue-specific global fluorination of Candida antarctica lipase B in Pichia pastoris.
PubMed:Non-ionic surfactant modified ligand exchange chromatography using copper (II) complex of N,N-dimethyl-L-phenylalanine as the chiral additive for enantioselective amino acids separation.
PubMed:Amino acid ionic liquids as chiral ligands in ligand-exchange chiral separations.
PubMed:alpha(2)-Adrenoceptors mediate the acute inhibitory effect of fluoxetine on locus coeruleus noradrenergic neurons.
PubMed:Oligopeptides and copeptides of homochiral sequence, via beta-sheets, from mixtures of racemic alpha-amino acids, in a one-pot reaction in water; relevance to biochirogenesis.
PubMed:Enantioseparation of dopa and related compounds by cyclodextrin-modified microemulsion electrokinetic chromatography.
PubMed:[Study on enantioselectivity of celluloses derived by phenylcarbamate at 2,3- or 2,3,6-positions].
PubMed:Stereospecificity of mushroom tyrosinase immobilized on a chiral and a nonchiral support.
PubMed:Evaluation of enantioselective gas chromatography for the determination of minute deviations from racemic composition of alpha-amino acids with emphasis on tyrosine: accuracy and precision of the method.
PubMed:Stereospecificity of horseradish peroxidase.
PubMed:Fluorescence spectroscopic study of alpha-chymotrypsin relevant to the enantioselectivity for optical resolution of amino acid esters in organic solvents.
PubMed:Crystal structure of a covalent intermediate of endogenous human arylsulfatase A.
PubMed:Unexpected differences between D- and L- tyrosine lead to chiral enhancement in racemic mixtures.
PubMed:Inhibition of tyrosine phenol-lyase from Citrobacter freundii by 2-azatyrosine and 3-azatyrosine.
PubMed:Structure--activity studies for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropanoic acid receptors: acidic hydroxyphenylalanines.
PubMed:[The effect of elymoclavine and its derivatives on various enzymes of the gastrointestinal tract].
PubMed:Tyrosine phosphorylation of human urokinase-type plasminogen activator.
PubMed:[The brain catecholamine systems in the regulation of dominance].
PubMed:Copper-deficient mice have higher cardiac norepinephrine turnover.
PubMed:The mechanism of amphetamine-induced inhibition of rat substantia nigra compacta neurones investigated with intracellular recording in vitro.
PubMed:Potential radiopharmaceuticals for the detection of ocular melanoma. Part III. A study with 14C and 11C labelled tyrosine and dihydroxyphenylalanine.
PubMed:[Disorder of catecholamine synthesis in early ontogeny and hypophyseal-adrenal cortical function in adult rats].
PubMed:Protease inhibition of natural killer (NK) and antibody-dependent cell-mediated cytoxicity (ADCC) activities.
PubMed:L-tyrosine regulation and biosynthesis via arogenate dehydrogenase in suspension-cultured cells of Nicotiana silvestris Speg. et Comes.
PubMed:An electrochemical assay system for peroxidase and peroxidase-couplers reactions based on a fluoride ion-selective electrode.
PubMed:The antifungal activity of carrier peptides, L-arginyl-X-L-phenylalanine, containing amino acid antagonists or atypical non-biogenic D-amino acids in the central position.
PubMed:Structural specificity in the renal tubular transport of tyrosine.
PubMed:Studies on the absorption of the pancreatic function test peptide, N-benzoyl-L-tyrosyl-p-aminobenzoic acid, and related compounds by isolated rat small intestine.
PubMed:[The secondary structure of amides of adenylic acid containing D- and L-aromatic amino acids].
PubMed:[Effect of cyclic compounds on pigment formation in Aspergillus niger cultures].
PubMed:[Photochemistry of aromatic amino acids in solution. I. DL-phenylalanine, DL-tyrosine and L-dopa].
PubMed:Amino Acid and vitamin requirements of several bacteroides strains.
PubMed:Inhibition of leaf process by p-fluorophenylalanine during induction of flowering in the cocklebur.
PubMed:Effects of ionizing radiations on L- and DL-tyrosine studied by ultra-violet and infra-red spectrophotometry.
PubMed:Incorporation of DL-tyrosine-2-C-14 and DL-tryptophan-2-C-14 by encysted Trichinella spiralis larvae.
PubMed:[Utilization of amino acids in the synthesis of purine compounds. III. Effect of dl-tyrosine and dl-tryptophan in the protein-deficient rat].
PubMed:Radioactivity distribution in the tissues of mice bearing melanosarcoma after administration of DL-tyrosine labeled with radioactive carbon.
PubMed:Studies in protein metabolism with compounds labeled with radioactive carbon; metabolism of dl-tyrosine in the normal and tumor-bearing rat.
None found
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