EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dextro,laevo-norleucine
DL-a-aminocaproic acid

Supplier Sponsors

Name:2-aminohexanoic acid
CAS Number: 616-06-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:210-462-7
FDA UNII: 5C81BE5GKK
Nikkaji Web:J1.268H
Beilstein Number:1721748
MDL:MFCD00064422
XlogP3:-1.50 (est)
Molecular Weight:131.17501000
Formula:C6 H13 N O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 234.00 °C. @ 760.00 mm Hg (est)
Flash Point: 204.00 °F. TCC ( 95.30 °C. ) (est)
logP (o/w): 0.920 (est)
Soluble in:
 water, 1.18E+04 mg/L @ 25 °C (exp)
 water, 1.569e+004 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
H-DL-Nle-OH 98%
Glentham Life Sciences
DL-norLeucine
sds
Santa Cruz Biotechnology
For experimental / research use only.
DL-norLeucine
Sigma-Aldrich: Sigma
For experimental / research use only.
DL-norLeucine
sds
TCI AMERICA
For experimental / research use only.
DL-norLeucine >98.0%(T)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for dextro,laevo-norleucine usage levels up to:
 not for fragrance use.
 
Recommendation for dextro,laevo-norleucine flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :9475
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
2-aminohexanoic acid
Chemidplus:0000327560
 
References:
 2-aminohexanoic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):9475
Pubchem (sid):135256923
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
Golm Metabolome Database:Search
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2922.49.4050
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
2-aminocaproic acid
DL-a-aminocaproic acid
(±)-2-aminohexanoic acid
2-aminohexanoic acid
(+-)-norleucine
D-(-)-norleucine
DL-norleucine
norleucine, D-(-)-
 

Articles:

PubMed:Non-physiological amino acid (NPAA) therapy targeting brain phenylalanine reduction: pilot studies in PAHENU2 mice.
PubMed:Solid-state phase transitions of DL-aminobutyric acid.
PubMed:Size-dependent phase stability of a molecular nanocrystal: a proxy for investigating the early stages of crystallization.
PubMed:Solid-state phase transitions in DL-norvaline studied by single-crystal X-ray diffraction.
PubMed:Solid-solid phase transitions in DL-norvaline studied by differential scanning calorimetry and Raman spectroscopy.
PubMed:Concerted molecular displacements in a thermally-induced solid-state transformation in crystals of DL-norleucine.
PubMed:Spontaneous resolution of binary copper(II) complexes with racemic dipeptides: crystal structures of glycyl-L-alpha-amino-n-butyrato copper(II) monohydrate, glycyl-D-valinato copper(II) hemihydrate, and glycyl-L-valinato copper(II) hemihydrate.
PubMed:Burkholderia fungorum sp. nov. and Burkholderia caledonica sp. nov., two new species isolated from the environment, animals and human clinical samples.
PubMed:Subsite preferences of pepstatin-insensitive carboxyl proteinases from prokaryotes: kumamolysin, a thermostable pepstatin-insensitive carboxyl proteinase.
PubMed:Separations of enantiomers by preparative capillary isotachophoresis.
PubMed:The effect of chlorambucil upon lysozyme activity.
PubMed:Identification of carboxyl residues in pepstatin-insensitive carboxyl proteinase from Pseudomonas sp. 101 that participate in catalysis and substrate binding.
PubMed:Substrate specificities of pepstatin-insensitive carboxyl proteinases from gram-negative bacteria.
PubMed:Characterisation of a thermostable pepstatin-insensitive acid proteinase from a Bacillus sp.
PubMed:A pepstatin-insensitive aspartic proteinase from a thermophilic Bacillus sp.
PubMed:Purification and some properties of a protease from Streptomyces limosus.
PubMed:Purification and characterization of an acid proteinase from Dirofilaria immitis worms.
PubMed:Effect of inhibitors of cell envelope synthesis on beta-sitosterol side chain degradation by Mycobacterium sp. NRRL MB 3683.
PubMed:Purification and characterization of kumamolysin, a novel thermostable pepstatin-insensitive carboxyl proteinase from Bacillus novosp. MN-32.
PubMed:Amino acid imbalance and intracellular protein synthesis.
PubMed:The gene and deduced protein sequences of the zymogen of Aspergillus niger acid proteinase A.
PubMed:Enhancement of drug susceptibility of Mycobacterium avium by inhibitors of cell envelope synthesis.
PubMed:Purification and Characterization of an Extracellular Acid Proteinase from the Ectomycorrhizal Fungus Hebeloma crustuliniforme.
PubMed:Methionine as methyl-group donor in the synthesis of Mycobacterium avium envelope lipids, and its inhibition by DL-ethionine, D-norleucine and DL-norleucine.
PubMed:Tuna pepsinogens and pepsins. Purification, characterization and amino-terminal sequences.
PubMed:Cathepsin D from human leukocytes. Purification by affinity chromatography and properties of the enzyme.
PubMed:Purification and properties of a pepstatin-insensitive carboxyl proteinase from a gram-negative bacterium.
PubMed:Interference by methionine on valine uptake in Acremonium chrysogenum.
PubMed:Purification of an acid protease from Mucor rouxii that inactivates chitin synthetase.
PubMed:Amino acid derived latent isocyanates: irreversible inactivation of porcine pancreatic elastase and human leukocyte elastase.
PubMed:Extracellular proteinases of the isolate of Botrytis cinerea virulent to apple tissues.
PubMed:Acid proteinase activity in fish--I. Comparative study of extraction of cathepsins B and D from Mujil auratus.
PubMed:Purification and characterization of pepsinogens and pepsins from Asiatic black bear, and amino acid sequence determination of the NH2-terminal 60 residues of the major pepsinogen.
PubMed:Identification of monkey lung procathepsin D-II as a pepsinogen-C-like acid protease zymogen.
PubMed:An aspartic proteinase from Fusarium moniliforme. Purification and general properties.
PubMed:Extracellular acid proteases produced by Saccharomycopsis lipolytica.
PubMed:Aspartyl proteinase from cucumber (Cucumis sativus) seeds. Preparation and characteristics.
PubMed:Protease activity associated with loss of adhesiveness in mouse teratocarcinoma.
PubMed:Proton magnetic resonance spectroscopy of an essential histidyl residue in a milk-clotting acid protease, Mucor rennin.
PubMed:Aryl-L-aminoacylamidase activities in extracts of Streptococcus durans.
PubMed:Photo-oxidation of a histidyl residue of milk-clotting acid protease, Mucor rennin.
PubMed:Studies on proteinases from the digestive organs of sardine. II. Purification and characterization of two acid proteinases from the stomach.
PubMed:Purification and properties of proteinase A from yeast.
PubMed:Cathepsins D from rhesus monkey lung. Purification and characterization.
PubMed:Monkey pepsinogens and pepsins. Monkey pepsinogens and pepsins. V. Purification, Characterization, and amino-terminal sequence determination of crab-eating monkey pepsinogens and pepsins.
PubMed:[Acid proteinase of chicken liver. Purification and properties (author's transl)].
PubMed:A cathepsin D-like acid proteinase from human gastric mucosa. Purification and characterization.
PubMed:Inhibition of the acid proteinase from Neurospora crassa by diazoacetyl-DL-norleucine methyl ester, 1,2-epoxy-3-(4-nitrophenoxy)propane and pepstatin.
PubMed:Purification and characterization of rat pepsinogens whose contents increase with developmental progress.
PubMed:The structure and function of acid proteases. IX. Isolation and amino acid sequences of the peptides containing the active site aspartyl residues reactive with diazoacetyl-DL-norleucine methyl ester and 1,2-epoxy-3-(p-nitrophenoxy)propane in Rhizopus chinensis acid protease.
PubMed:Nonsteroid anti-inflammatory agents: regulators of the phagocytic secretion of lysosomal enzymes from guinea-pig neutrophils.
PubMed:Inactivation of cathepsin D from human gastric mucosa and from stomach carcinoma by diazoacetyl-DL-norleucine methyl ester.
PubMed:Acid proteases. II. Fluorescence study of the interaction of Cladosporium acid protease with glycyl-DL-norleucine methyl ester in the presence of cupric ions.
PubMed:The structure and function of acid proteases. VIII. Purification and characterization of cathepsins D from Japanese monkey lung.
PubMed:Acid proteases. I. Inactivation of Cladosporium acid protease by diazoacetyl-DL-norleucine methyl ester as an active-site-directed irreversible inhibitor.
PubMed:Sulfur metabolism of a mutant of Cephalosporium acremonium with enhanced potential to utilize sulfate for cephalosporin C production.
PubMed:Pepsinogen C and pepsin C from gastric mucosa of Japanese monkey. Purification and characterization.
PubMed:The structure and function of acid proteases. VI. Effects of acid protease-specific inhibitors on the acid proteases from Aspergillus niger var. macrosporus.
PubMed:The structure and function of acid proteases. V. Comparative studies on the specific inhibition of acid proteases by diazoacetyl-DL-norleucine methyl ester, 1,2-epoxy-3-(p-nitrophenoxy) propane and pepstatin.
PubMed:The structure and function of acid proteases. IV. Inactivation of the acid protease from Mucor pusillus by acid protease-specific inhibitors.
PubMed:Pepsinogens and pepsins from gastric mucosa of Japanese Monkey. Purification and characterization.
PubMed:Purification and properties of the thermostable acid protease of Penicillium duponti.
PubMed:Effect of norleucine on mycelial fragmentation in Cephalosporium acremonium.
PubMed:The relevance of the structure of lysine bound to Sepharose for the affinity of rabbit plasminogen;.
PubMed:Specific inhibition of acid proteases from brain, kidney, skeletal muscle, and insectivorous plants by diazoacetyl-DL-norleucine methyl ester and by pepstatin.
PubMed:Kinetics of irreversible enzyme inhibition by an unstable inhibitor.
PubMed:The structure and function of acid proteases. Specific inactivation of an acid protease from Rhizopus chinensis by diazoacetyl-DL-norleucine methyl ester.
PubMed:An active site peptide from pepsin C.
PubMed:Amino acid cross resistance in Agrobacterium tumefaciens.
PubMed:Biosynthesis of chloramphenicol. IV. Incorporation of carbon 14-labled precursors.
PubMed:Nitrogenous compounds in germination and postgerminative development of Bacillus megaterium spores.
PubMed:Induced alterations in metabolism of DL-norleucine-2-C14 in the intact cow.
PubMed:Metabolism of DL-alpha-aminobutyrate-3-14C and DL-norleucine-3-14C.
 
Notes:
None found
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