EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dextro,laevo-cycloserine
DL-cycloserine

Supplier Sponsors

Name:4-amino-1,2-oxazolidin-3-one
CAS Number: 68-39-3Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:200-687-9
FDA UNII: Search
Nikkaji Web:J60.873D
MDL:MFCD00064323
XlogP3-AA:-1.50 (est)
Molecular Weight:102.09322000
Formula:C3 H6 N2 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:white to pale yellow crystals (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 155.00 °C. @ 760.00 mm Hg (est)
Flash Point: 32.00 °F. TCC ( 0.00 °C. ) (est)
logP (o/w): -1.840 (est)
Soluble in:
 water, 1.655e+005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
DL-Cycloserine 98%
Odor: characteristic
Use: Antibacterial (tuberculostatic).
Glentham Life Sciences
DL-Cycloserine crystalline
Santa Cruz Biotechnology
For experimental / research use only.
rac Cycloserine
Sigma-Aldrich: Sigma
For experimental / research use only.
DL-Cycloserine crystalline
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 3200 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 21, Pg. 298, 1971.

intravenous-mouse LD50 2814 mg/kg
Farmaco, Edizione Scientifica. Vol. 13, Pg. 447, 1958.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for dextro,laevo-cycloserine usage levels up to:
 not for fragrance use.
 
Recommendation for dextro,laevo-cycloserine flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :401
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
4-amino-1,2-oxazolidin-3-one
Chemidplus:0000068393
RTECS:NY2974900 for cas# 68-39-3
 
References:
 4-amino-1,2-oxazolidin-3-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):401
Pubchem (sid):134971213
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C06682
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2934.90.5000
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
4-amino-1,2-oxazolidin-3-one
4-amino-3-isoxazolidone
DL-cycloserine
3-isoxazolidinone, 4-amino-
 

Articles:

PubMed:Mechanism of synergy between epigallocatechin gallate and beta-lactams against methicillin-resistant Staphylococcus aureus.
PubMed:The glutathione dependence of inorganic sulfate formation from L- or D-cysteine in isolated rat hepatocytes.
PubMed:Alanine and hyperosmolarity are responsible for the stimulation of cardiomyocyte glucose transport by samples containing a glucose tolerance factor.
PubMed:Inhibition of urea-cycle activity by high concentrations of alanine.
PubMed:Beta-cyanoalanine synthase: purification and characterization.
PubMed:[Allergic manifestations due to dl-cycloserine (oxamycin)].
PubMed:[Chemical and microbiological determination of the liberation of antitubercular agents from emulsion and suspension systems. 1. Streptomycin sulfate, rifamycin SV sodium, DL-cycloserine].
PubMed:[COMPARATIVE STUDY OF THE FUNCTIONAL AND MORPHOLOGICAL CHANGES IN THE CENTRAL NERVOUS SYSTEM OF WHITE RATS FOLLOWING INTERMITTENT ADMINISTRATION OF DL-CYCLOSERINE].
PubMed:[Comparative study of functional and morphological changes under the action of dl-cycloserine on the central nervous system].
PubMed:[Relation between dl-cycloserine and d-cycloserine and the effect on the convulsive action of various analeptics].
PubMed:Inhibition of glutamic-pyruvic transaminase by DL-cycloserine and other compounds.
PubMed:[Effect of dl-cycloserine on the nervous system].
PubMed:Formation of DL-cycloserine from the methyl ester of dl-aminoxyalanine.
PubMed:[Circulation of D-cycloserine & Czechosiovak DL-cycloserine in the organism].
PubMed:[Formation of dl-cycloserine from beta-hydroxaminoalanine methyl ester].
 
Notes:
None found
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