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Category:pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 228.50 °C. @ 760.00 mm Hg
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| Boiling Point: | 57.30 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 218.000000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est)
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| logP (o/w): | 0.632 (est) |
| Soluble in: |
| | water, 1.00E+06 mg/L @ 25 °C (exp) | | | water, 1e+006 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-guinea pig LD50 9500 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(1), Pg. 71, 1984.
intraperitoneal-mouse LD50 960 mg/kg
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
BEHAVIORAL: TREMOR
Japanese Journal of Pharmacology. Vol. 17, Pg. 475, 1967.
intravenous-mouse LD50 320 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 112, Pg. 36, 1957.
oral-mouse LD50 4860 mg/kg
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 31(1), Pg. 49, 1987.
oral-rat LD50 9900 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 49(1), Pg. 71, 1984.
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| Dermal Toxicity: |
subcutaneous-mouse LD50 1130 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 112, Pg. 36, 1957.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | pharmaceuticals / chemical synthisis |
| Recommendation for diethyl amine hydrochloride usage levels up to: | | | not for fragrance use.
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| Recommendation for diethyl amine hydrochloride flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | diethylamine hydrochloride | | | diethylamine, chloride | | | diethylamine, hydrochloride | | | diethylaminehydrochloride | | | diethylammonium chloride | | | diethylazanium;chloride | | | ethanamine, N-ethyl-, hydrochloride (1:1) | | | ethylamine, N-ethyl-, hydrochloride | | N- | ethylethanamine hydrochloride | | N- | ethylethanaminium chloride |
Articles:
| PubMed:Synthesis of novel 2-(substituted amino)alkylthiopyrimidin-4(3H)-ones as potential antimicrobial agents. |
| PubMed:Determination of butenafine hydrochloride in human plasma by liquid chromatography electrospray ionization-mass spectrometry following its topical administration in human subjects. |
| PubMed:Scalable synthesis of (1-cyclopropyl)cyclopropylamine hydrochloride. |
| PubMed:Formulation and evaluation of verapamil hydrochloride loaded solid lipid microparticles. |
| PubMed:Use of N, N-diethyl-p-phenylenediamine sulphate for the spectrophotometric determination of some phenolic and amine drugs. |
| PubMed:A 4-aminoquinoline derivative that markedly sensitizes tumor cell killing by Akt inhibitors with a minimum cytotoxicity to non-cancer cells. |
| PubMed:A simple and sensitive HPLC method for quantitation of low phenoprolamine hydrochloride concentrations in human plasma and its pharmacokinetic application. |
| PubMed:Biochemical manipulation via iron chelation to enhance porphyrin production from porphyrin precursors. |
| PubMed:NO-1886, a lipoprotein lipase activator, attenuates vascular smooth muscle contraction in rat aorta. |
| PubMed:Development and validation of a liquid chromatographic/tandem mass spectrometric method for the determination of sertraline in human plasma. |
| PubMed:Ropinirole hydrochloride, a dopamine agonist. |
| PubMed:Tableting of Eudragit RS and propranolol hydrochloride solid dispersion: effect of particle size, compaction force, and plasticizer addition on drug release. |
| PubMed:Aminated polysaccharide microspheres as DNA delivery systems. |
| PubMed:Spatial relationship between the prodan site, Trp-214, and Cys-34 residues in human serum albumin and loss of structure through incremental unfolding. |
| PubMed:Fluorescent labeling of drugs and simple organic compounds containing amine functional groups, utilizing dansyl chloride in Na(2)CO(3) buffer. |
| PubMed:Excitation of rat striatal large neurons by dopamine and/or glutamate released from nerve terminals via presynaptic nicotinic receptor (A4beta2 type) stimulation. |
| PubMed:Regulated workplace ketones and their interference in the PFBHA method for aldehydes. |
| PubMed:Application of first-derivative UV-spectrophotometry, TLC-densitometry and liquid chromatography for the simultaneous determination of mebeverine hydrochloride and sulpiride. |
| PubMed:Actions of adenosine A2A receptor antagonist KW-6002 on drug-induced catalepsy and hypokinesia caused by reserpine or MPTP. |
| PubMed:Electrophysiological characterization of BRL-32872 in canine Purkinje fiber and ventricular muscle. Effect on early after-depolarizations and repolarization dispersion. |
| PubMed:Role of edrophonium in prevention of the re-inhibition of acetylcholinesterase by phosphorylated oxime. |
| PubMed:Electromechanical effects of newly synthetized propafenone derivatives on isolated guinea-pig heart muscle preparations. |
| PubMed:Endothelin-1 and endothelin-3 modulate dopaminergic neurons through different mechanisms. |
| PubMed:Modification of pig kidney diamine oxidase with ethoxyformic anhydride and rose bengal: evidence for essential histidyl residue at the active site. |
| PubMed:Improved high-performance liquid chromatographic assay for the stereoselective determination of mexiletine in plasma. |
| PubMed:[High-performance liquid chromatographic determination of propanidid and etomidate]. |
| PubMed:Tamoxifen inhibition of prolactin action in the mouse mammary gland. |
| PubMed:[Chemical constituents of the leaves of Crataegus pinnatifida Bge. var. major N. E. Br]. |
| PubMed:High-performance liquid chromatographic determination of phenylpropanolamine in human plasma and urine, using column switching combined with ion-pair chromatography. |
| PubMed:Antiestrogen inhibition of prolactin-induced growth of the Nb2 rat lymphoma cell line. |
| PubMed:Antiulcerogenic and antisecretory effects of a novel diphenylmethane derivative and antiestrogen binding site ligand. |
| PubMed:High-performance liquid chromatographic assay for dilevalol in human plasma and urine using a PRP-1 column and fluorimetric detection. |
| PubMed:Histamine and growth: interaction of antiestrogen binding site ligands with a novel histamine site that may be associated with calcium channels. |
| PubMed:Prostaglandin production by the guinea-pig endometrium: is calcium necessary? |
| PubMed:[Hemodynamic effects of intravenously administered celiprolol in patient with coronary heart disease and depressed left ventricular function]. |
| PubMed:Psychopharmacology of midalcipran, 1-phenyl-1-diethyl-amino-carbonyl-2-aminomethylcyclopropane hydrochloride (F 2207), a new potential antidepressant. |
| PubMed:Biochemical profile of midalcipran (F 2207), 1-phenyl-1-diethyl-aminocarbonyl-2-aminomethyl-cyclopropane (Z) hydrochloride, a potential fourth generation antidepressant drug. |
| PubMed:Simultaneous determination of oxprenolol and 2H6-labelled oxprenolol in human plasma by gas chromatography/mass spectrometry. |
| PubMed:Synthesis of some benzofuran and furocoumarin derivatives for possible biological activity. |
| PubMed:[Pupillometry, a clinical pharmacological model / Relevance and limits (author's transl)]. |
| PubMed:Tumor induction in C57BL X C3HF1 mice following single oral administration of diethylamine hydrochloride (DEA . HCl) and sodium nitrite (NaNO2). |
| PubMed:A modified gas-liquid chromatographic assay to monitor plasma mexiletine in a tinnitus study. |
| PubMed:Improved stability of methanolic Wright's stain solution with dual additives. |
| PubMed:Improved stability of methanolic wright's stain with additive reagents. |
| PubMed:[Pharmacological study on treptilamine in man/study on tolerability (author's transl)]. |
| PubMed:[Synthesis of radioactively labelled reproterol hydrochloride (author's transl)]. |
| PubMed:Synthesis of the antileukemic compound N,N(11)-[5-[bis(2-chloroethyl)amino]-1, 3-phenylene]bisurea. |
| PubMed:Microbial oxidation of amines. Partial purification of a trimethylamine mono-oxygenase from Pseudomonas aminovorans and its role in growth on trimethylamine. |
| PubMed:Effects of chloroform, diethyl ether and a propiophenone derivative, 3-dimethylamino-2-methyl-2-phenoxypropiophenone hydrochloride, upon cyclic 3',5'-nucleotide phosphodiesterase. |
| PubMed:[Effect of 2 butoxy-3 aminobenzoate hydrochloride of diethyl aminoethyl on 2 types of neural conduction]. |
| PubMed:A pharmacological study of n,n-diethyl-[5-(2,4-dichlorophenyl)-4-thiapentyl] amine hydrochloride. |
| PubMed:Distribution studies in mice following the intravenous injection of diethyl beta-iodoethyl amine hydrochloride prepared with radioactive iodine. |
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3D/inchi