EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dextro-(+)-tryptophan
D-tryptophan

Supplier Sponsors

CAS Number: 153-94-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:205-819-9
FDA UNII: 7NS97N9H1G
Nikkaji Web:J9.185E
Beilstein Number:086198
MDL:MFCD00005647
XlogP3:-1.10 (est)
Molecular Weight:204.22904000
Formula:C11 H12 N2 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:White solid (est)
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 447.91 °C. @ 760.00 mm Hg (est)
Flash Point: 436.00 °F. TCC ( 224.70 °C. ) (est)
logP (o/w): 0.704 (est)
Soluble in:
 water, 2848 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Anhui Haibei
D-Tryptophan
BOC Sciences
For experimental / research use only.
(R)-(+)-2-Amino-3-(3-indolyl)propionic Acid 95%
Changzhou Longo Chemical
D-Tryptophan
Glentham Life Sciences
D-Tryptophan
Penta International
D-TRYPTOPHAN
Santa Cruz Biotechnology
For experimental / research use only.
D-Tryptophan ≥99%
Sigma-Aldrich: Sigma
For experimental / research use only.
D-Tryptophan ≥98.0% (HPLC)
TCI AMERICA
For experimental / research use only.
D-Tryptophan >98.0%(HPLC)(T)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-rat LD50 4289 mg/kg
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Archives of Biochemistry and Biophysics. Vol. 64, Pg. 319, 1956.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for dextro-(+)-tryptophan usage levels up to:
 not for fragrance use.
 
Recommendation for dextro-(+)-tryptophan flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):153-94-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :9060
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(2R)-2-amino-3-(1H-indol-3-yl)propanoic acid
Chemidplus:0000153946
EPA/NOAA CAMEO:hazardous materials
RTECS:YN6129000 for cas# 153-94-6
 
References:
 (2R)-2-amino-3-(1H-indol-3-yl)propanoic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):9060
Pubchem (sid):134974088
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
KEGG (GenomeNet):C00525
HMDB (The Human Metabolome Database):HMDB13609
FooDB:FDB029595
YMDB (Yeast Metabolome Database):YMDB00998
Export Tariff Code:2933.99.1200
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
(R)-2-amino-3-(1H-indol-3-yl)-propionic acid
(2R)-2-amino-3-(1H-indol-3-yl)propanoic acid
(R)-2-amino-3-(1H-indol-3-yl)propanoic acid
(R)-(+)-2-amino-3-(3-indolyl)propionic acid
(R)-2-amino-3-(3-indolyl)propionic acid
(2R)-2-amino-3-indol-3-ylpropanoic acid
(R)-a-amino-3-indolepropionic acid
D-a-amino-3-indolepropionic acid
(R)-a-aminoindole-3-propanoic acid
D-tryptofaan
(+)-tryptophan
(R)-tryptophan
D-tryptophan
D-(+)-tryptophan
 tryptophan, D-
D-trytophane
 

Articles:

PubMed:Selective recognition of d-tryptophan from d/l-tryptophan mixtures in the presence of Cu(II) by electropolymerized l-lysine film.
PubMed:1-Methyl-D-Tryptophan Potentiates TGF-β-Induced Epithelial-Mesenchymal Transition in T24 Human Bladder Cancer Cells.
PubMed:Effects of indoleamine 2,3-dioxygenase inhibitor in non-Hodgkin lymphoma model mice.
PubMed:Tryptophan Lyase (NosL): Mechanistic Insights from Substrate Analogues and Mutagenesis.
PubMed:The effects of D-Tyrosine combined with amikacin on the biofilms of Pseudomonas aeruginosa.
PubMed:N-acetyl-l-tryptophan, but not N-acetyl-d-tryptophan, rescues neuronal cell death in models of amyotrophic lateral sclerosis.
PubMed:Trial watch: IDO inhibitors in cancer therapy.
PubMed:Growth Inhibition of Listeria monocytogenes, Salmonella enterica, and Escherichia coli O157:H7 by D-tryptophan as an incompatible solute.
PubMed:Identification and characterization of mutations conferring resistance to D-amino acids in Bacillus subtilis.
PubMed:MRZ-99030 - A novel modulator of Aβ aggregation: I - Mechanism of action (MoA) underlying the potential neuroprotective treatment of Alzheimer's disease, glaucoma and age-related macular degeneration (AMD).
PubMed:Enantioseparation of (DL)-tryptophan by spiral tube assembly counter-current chromatography and evaluation of mass transfer rate for enantiomers.
PubMed:Comparison of centrally injected tryptophan-related substances inducing sedation in acute isolation stress-induced neonatal chicks.
PubMed:The urinary ratio of 3-hydroxykynurenine/3-hydroxyanthranilic acid is an index to predicting the adverse effects of D-tryptophan in rats.
PubMed:Structure of the cyclic peptide [W8S]contryphan Vn: effect of the tryptophan/serine substitution on trans-cis proline isomerization.
PubMed:Contributions of tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase to the conversion of D-tryptophan to nicotinamide analyzed by using tryptophan 2,3-dioxygenase-knockout mice.
PubMed:Chirality sensitive binding of tryptophan enantiomers with pristine single wall carbon nanotubes.
PubMed:R-Configuration of 4-Aminopyridyl-Based Inhibitors of CYP51 Confers Superior Efficacy Against Trypanosoma cruzi.
PubMed:Kynurenine production mediated by indoleamine 2,3-dioxygenase aggravates liver injury in HBV-specific CTL-induced fulminant hepatitis.
PubMed:Indoleamine 2,3-dioxygenase inhibition alters the non-coding RNA transcriptome following renal ischemia-reperfusion injury.
PubMed:Biochemical investigations of two 6-DMATS enzymes from Streptomyces reveal new features of L-tryptophan prenyltransferases.
PubMed:Suppression of immunodominant antitumor and antiviral CD8+ T cell responses by indoleamine 2,3-dioxygenase.
PubMed:Stereoselective preparation of pyridoxal 1,2,3,4-tetrahydro-β-carboline derivatives and the influence of their absolute and relative configuration on the proliferation of the malaria parasite Plasmodium falciparum.
PubMed:Endothelin-1 stimulates resistin gene expression.
PubMed:[Levo-L-methyl tryptophan induces immune imbalance at maternal-fetal interface in mice].
PubMed:A method for the determination of D-kynurenine in biological tissues.
PubMed:Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease.
PubMed:D-amino acids indirectly inhibit biofilm formation in Bacillus subtilis by interfering with protein synthesis.
PubMed:Use of a fundamental approach to spray-drying formulation design to facilitate the development of multi-component dry powder aerosols for respiratory drug delivery.
PubMed:IDO1 plays an immunosuppressive role in 2,4,6-trinitrobenzene sulfate-induced colitis in mice.
PubMed:On-line sample preconcentration by sweeping and poly(ethylene oxide)-mediated stacking for simultaneous analysis of nine pairs of amino acid enantiomers in capillary electrophoresis.
PubMed:Effect of 1-methyl-D-tryptophan and adoptive transfer of dendritic cells on polymicrobial sepsis induced by cecal content injection.
PubMed:Mutation of cysteine residues alters the heme-binding pocket of indoleamine 2,3-dioxygenase-1.
PubMed:Stereospecific approach to the synthesis of ring-A oxygenated sarpagine indole alkaloids. Total synthesis of the dimeric indole alkaloid P-(+)-dispegatrine and six other monomeric indole alkaloids.
PubMed:Starmerella caucasica sp. nov., a novel anamorphic yeast species isolated from flowers in the Caucasus.
PubMed:L-tryptophan suppresses rise in blood glucose and preserves insulin secretion in type-2 diabetes mellitus rats.
PubMed:Tetrahydro-β-carboline-based spirocyclic lactam as type II' β-turn: application to the synthesis and biological evaluation of somatostatine mimetics.
PubMed:IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan.
PubMed:Amino acids and peptides activate at least five members of the human bitter taste receptor family.
PubMed:Molecular cloning of two distinct precursor genes of NdWFamide, a d-tryptophan-containing neuropeptide of the sea hare, Aplysia kurodai.
PubMed:Serum stability of selected decapeptide agonists of KISS1R using pseudopeptides.
PubMed:Cyclization of fungal nonribosomal peptides by a terminal condensation-like domain.
PubMed:D-amino acids for the enhancement of a binary biocide cocktail consisting of THPS and EDDS against an SRB biofilm.
PubMed:Kynurenic acid and 3-hydroxykynurenine production from D-kynurenine in mice.
PubMed:Unraveling complex small-molecule binding mechanisms by using simple NMR spectroscopy.
PubMed:Effects of indoleamine 2,3-dioxygenases in carbon tetrachloride-induced hepatitis model of rats.
PubMed:Flexible enantioselectivity of tryptophanase attributable to benzene ring in heterocyclic moiety of d-tryptophan.
PubMed:Alteration in the plasma concentration of a DAAO inhibitor, 3-methylpyrazole-5-carboxylic acid, in the ketamine-treated rats and the influence on the pharmacokinetics of plasma D-tryptophan.
PubMed:Pharmacological characteristics of endokinin C/D-derived peptides in nociceptive and inflammatory processing in rats.
PubMed:Fatal pancreatitis in simian immunodeficiency virus SIV(mac251)-infected macaques treated with 2',3'-dideoxyinosine and stavudine following cytotoxic-T-lymphocyte-associated antigen 4 and indoleamine 2,3-dioxygenase blockade.
PubMed:Novel action of 3,4-DAA ameliorating acute liver allograft injury.
PubMed:The indoleamine-2,3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells.
PubMed:Three new cytochalasins from the marine-derived fungus Spicaria elegans KLA03 by supplementing the cultures with L- and D-tryptophan.
PubMed:[Presumptive identification of Cryptococcus gattii isolated from Terminalia catappa in Montería city, Córdoba, Colombia].
PubMed:Association analysis of DTD1 gene variations with aspirin-intolerance in asthmatics.
PubMed:An accessory protein required for anchoring and assembly of amyloid fibres in B. subtilis biofilms.
PubMed:Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice.
PubMed:Inhibitor of indoleamine-2,3-dioxygenase 1-methyl-D-tryptophan can stimulate the growth of immunogenic tumors.
PubMed:A mechanistic approach for the DNA binding of chiral enantiomeric L- and D-tryptophan-derived metal complexes of 1,2-DACH: cleavage and antitumor activity.
PubMed:Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model.
PubMed:Cryptococcus gattii meningoencephalitis in an HIV-negative patient from the Peruvian Andes.
PubMed:High-performance affinity monolith chromatography for chiral separation and determination of enzyme kinetic constants.
PubMed:Structural features of phenoxycarbonylimino neonicotinoids acting at the insect nicotinic receptor.
PubMed:Thermodynamic origin of selective binding of β-cyclodextrin derivatives with chiral chromophoric substituents toward steroids.
PubMed:Anti-invasive and antiangiogenic effects of MMI-166 on malignant glioma cells.
PubMed:D-amino acids trigger biofilm disassembly.
PubMed:The ternary complex of PrnB (the second enzyme in the pyrrolnitrin biosynthesis pathway), tryptophan, and cyanide yields new mechanistic insights into the indolamine dioxygenase superfamily.
PubMed:Enantiospecific total synthesis of the important biogenetic intermediates along the ajmaline pathway, (+)-polyneuridine and (+)-polyneuridine aldehyde, as well as 16-epivellosimine and macusine A.
PubMed:In situ ATR-FTIR investigation on the preparation and enantiospecificity of chiral polyelectrolyte multilayers.
PubMed:Synthesis, cytotoxicity and antileishmanial activity of some N-(2-(indol-3-yl)ethyl)-7-chloroquinolin-4-amines.
PubMed:Total synthesis and configurational assignment of chondramide A.
PubMed:Synthesis, molecular modeling and biological evaluation of novel tadalafil analogues as phosphodiesterase 5 and colon tumor cell growth inhibitors, new stereochemical perspective.
PubMed:Mesenchymal stem cells inhibit complement activation by secreting factor H.
PubMed:Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2.
PubMed:Clean synthesis of molecular recognition polymeric materials with chiral sensing capability using supercritical fluid technology. Application as HPLC stationary phases.
PubMed:Photoactive ligands probing the sweet taste receptor. Design and synthesis of highly potent diazirinyl D-phenylalanine derivatives.
PubMed:Enantioseparation and amperometric detection of chiral compounds by in situ molecular imprinting on the microchannel wall.
PubMed:D-amino acid oxidase generates agonists of the aryl hydrocarbon receptor from D-tryptophan.
PubMed:Taste perception of monosodium glutamate and inosine monophosphate by 129P3/J and C57BL/6ByJ mice.
PubMed:Influence of exogenous gonadotropin-releasing hormone on seasonal reproductive behavior of the coyote (Canis latrans).
PubMed:Tryptophanase-catalyzed L-tryptophan synthesis from D-serine in the presence of diammonium hydrogen phosphate.
PubMed:A straightforward total synthesis of (-)-chaetominine.
PubMed:The biosynthetic pathway of crucifer phytoalexins and phytoanticipins: de novo incorporation of deuterated tryptophans and quasi-natural compounds.
PubMed:Annotating enzymes of uncertain function: the deacylation of D-amino acids by members of the amidohydrolase superfamily.
PubMed:Nascent structure-activity relationship study of a diastereomeric series of kappa opioid receptor antagonists derived from CJ-15,208.
PubMed:Combined effect of antiretroviral therapy and blockade of IDO in SIV-infected rhesus macaques.
PubMed:Aromatic D-amino acids act as chemoattractant factors for human leukocytes through a G protein-coupled receptor, GPR109B.
PubMed:Blockade of indoleamine 2,3-dioxygenase protects mice against lipopolysaccharide-induced endotoxin shock.
PubMed:Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo.
PubMed:Overexpression of indoleamine 2,3-dioxygenase in human endometrial carcinoma cells induces rapid tumor growth in a mouse xenograft model.
PubMed:Determination of the enantiomeric composition of some molecules of pharmaceutical interest by chemometric analysis of the UV spectra of guest-host complexes formed with modified cyclodextrins.
PubMed:The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation.
PubMed:Effects of central administration of gonadotropin-releasing hormone agonists and antagonist on elevated plus-maze and social interaction behavior in rats.
PubMed:Enantiospecific synthesis of (+)-alstonisine via a stereospecific osmylation process.
PubMed:Linear and cyclic peptides from the entomopathogenic bacterium Xenorhabdus nematophilus.
PubMed:Kinetic determination of tryptophan by using the B-Z oscillating chemical system.
PubMed:Indoleamine 2,3-dioxygenase expression promotes renal ischemia-reperfusion injury.
PubMed:Quantitation of cardioexcitatory Asn-D-Trp-Phe-NH2 diastereomers in Aplysia's central nervous system by nanoscale liquid chromatography-tandem mass spectrometry.
PubMed:Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway.
PubMed:Total synthesis and initial structure-activity relationships of longicatenamycin A.
PubMed:Growth and pigment production on D-tryptophan medium by Cryptococcus gattii, Cryptococcus neoformans, and Candida albicans.
PubMed:Abatacept modulates human dendritic cell-stimulated T-cell proliferation and effector function independent of IDO induction.
PubMed:Phospholipid-protein coatings for chiral capillary electrochromatography.
PubMed:Allelic variation of the Tas1r3 taste receptor gene selectively affects taste responses to sweeteners: evidence from 129.B6-Tas1r3 congenic mice.
PubMed:Fluorescence sensing and selective binding of L- and D-tryptophan-modified permethylated beta-cyclodextrins for aliphatic oligopeptides.
PubMed:[Design and synthesis of cholecystokinin-4 dipeptide analogues with anxiolytic and anxiogenic activities].
PubMed:Toxicology and pharmacokinetics of 1-methyl-d-tryptophan: absence of toxicity due to saturating absorption.
PubMed:Proapoptotic activity of indoleamine 2,3-dioxygenase expressed in renal tubular epithelial cells.
PubMed:Discovery of a dual action first-in-class peptide that mimics and enhances CNS-mediated actions of thyrotropin-releasing hormone.
PubMed:Recombinant polycistronic structure of hydantoinase process genes in Escherichia coli for the production of optically pure D-amino acids.
PubMed:Inherently chiral molecular clips: synthesis, chiroptical properties, and application to chiral discrimination.
PubMed:Phosphoramidate pronucleotides: a comparison of the phosphoramidase substrate specificity of human and Escherichia coli histidine triad nucleotide binding proteins.
PubMed:Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition.
PubMed:Immunocytochemical visualization of D-glutamate in the rat brain.
PubMed:Preliminary crystallographic characterization of PrnB, the second enzyme in the pyrrolnitrin biosynthetic pathway.
PubMed:Prevention of severe menorrhagia in oncology patients with treatment-induced thrombocytopenia by luteinizing hormone-releasing hormone agonist and depo-medroxyprogesterone acetate.
PubMed:In vitro evaluation of biospecific and pseudobiospecific ligands aimed at extracorporeal treatment for immunoglobulin E removal.
PubMed:Is glycine "sweet" to mice? Mouse strain differences in perception of glycine taste.
PubMed:Taste responses to sweet stimuli in alpha-gustducin knockout and wild-type mice.
PubMed:Bis(glycinium) oxalate: evidence of strong hydrogen bonding.
PubMed:Membrane association and contact formation by a synthetic analogue of polymyxin B and its fluorescent derivatives.
PubMed:Biosynthesis of indocarbazostatin B, incorporation of D-[U-13C] glucose and L-[2-13C] tryptophan.
PubMed:Sensitive high-performance liquid chromatographic assay for D-amino-acid oxidase activity in mammalian tissues using a fluorescent non-natural substrate, 5-fluoro-D-tryptophan.
PubMed:Characterization of bovine serum albumin-tryptophan interaction by capillary isoelectric focusing with whole column imaging detection.
PubMed:Reactive oxygen species generation is involved in epidermal growth factor receptor transactivation through the transient oxidization of Src homology 2-containing tyrosine phosphatase in endothelin-1 signaling pathway in rat cardiac fibroblasts.
PubMed:General approach for the synthesis of 12-methoxy-substituted sarpagine indole alkaloids including (-)-12-methoxy-N(b)-methylvoachalotine, (+)-12-methoxy-N(a)-methylvellosimine, (+)-12-methoxyaffinisine, and (-)-fuchsiaefoline.
PubMed:Indoleamine 2,3-dioxygenase participates in the interferon-gamma-induced cell death process in cultured bovine luteal cells.
PubMed:[Pharmacokinetics and pharmacodynamics of triptorelin].
PubMed:Diastereomeric molecular recognition and binding behavior of bile acids by L/D-tryptophan-modified beta-cyclodextrins.
PubMed:Induction of apoptosis in HL-60 cells by skimmed milk digested with a proteolytic enzyme from the yeast Saccharomyces cerevisiae.
PubMed:Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis.
PubMed:Purification, characterization, gene cloning and nucleotide sequencing of D: -stereospecific amino acid amidase from soil bacterium: Delftia acidovorans.
PubMed:Esterification of Escherichia coli tRNAs with D-histidine and D-lysine by aminoacyl-tRNA synthetases.
PubMed:A general strategy for the synthesis of vincamajine-related indole alkaloids: stereocontrolled total synthesis of (+)-dehydrovoachalotine, (-)-vincamajinine, and (-)-11-methoxy-17-epivincamajine as well as the related quebrachidine diol, vincamajine diol, and vincarinol.
PubMed:Determination of protein-ligand binding affinity by NMR: observations from serum albumin model systems.
PubMed:Formation of D-tyrosyl-tRNATyr accounts for the toxicity of D-tyrosine toward Escherichia coli.
PubMed:Optimization of ultrafiltration/diafiltration processes for partially bound impurities.
PubMed:Temperature-sensitive polymer-conjugated IFN-gamma induces the expression of IDO mRNA and activity by fibroblasts populated in collagen gel (FPCG).
PubMed:Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes.
PubMed:The first gamma-carboxyglutamic acid-containing contryphan. A selective L-type calcium ion channel blocker isolated from the venom of Conus marmoreus.
PubMed:Solution structure of the cyclic peptide contryphan-Vn, a Ca2+-dependent K+ channel modulator.
PubMed:[Effect of various methods of oxygenation in the isolated small intestine on the tryptophan and glycine accumulation].
PubMed:Allelic variation of the Tas1r3 taste receptor gene selectively affects behavioral and neural taste responses to sweeteners in the F2 hybrids between C57BL/6ByJ and 129P3/J mice.
PubMed:Stereocontrolled total synthesis of (-)-vincamajinine and (-)-11-methoxy-17-epivincamajine.
PubMed:Behavioral study in the gray mouse lemur (Microcebus murinus) using compounds considered sweet by humans.
PubMed:Regiospecific, enantiospecific total synthesis of the 12-alkoxy-substituted indole alkaloids, (+)-12-methoxy-Na-methylvellosimine, (+)-12-methoxyaffinisine, and (-)-fuchsiaefoline.
PubMed:General approach for the synthesis of sarpagine indole alkaloids. Enantiospecific total synthesis of (+)-vellosimine, (+)-normacusine B, (-)-alkaloid Q3, (-)-panarine, (+)-Na-methylvellosimine, and (+)-Na-methyl-16-epipericyclivine.
PubMed:Delftia tsuruhatensis sp. nov., a terephthalate-assimilating bacterium isolated from activated sludge.
PubMed:Inhibition of indoleamine 2,3-dioxygenase activity in IFN-gamma stimulated astroglioma cells decreases intracellular NAD levels.
PubMed:Proliferation of peripheral blood mononuclear cells is suppressed by the indoleamine 2,3-dioxygenase expression of interferon-gamma-treated skin cells in a co-culture system.
PubMed:Immune cell proliferation is suppressed by the interferon-gamma-induced indoleamine 2,3-dioxygenase expression of fibroblasts populated in collagen gel (FPCG).
PubMed:The enantiospecific, stereospecific total synthesis of the ring-A oxygenated sarpagine indole alkaloids (+)-majvinine, (+)-10-methoxyaffinisine, and (+)-N(a)-methylsarpagine, as well as the total synthesis of the alstonia bisindole alkaloid macralstonidine.
PubMed:Some sweet and bitter tastants stimulate inhibitory pathway of adenylyl cyclase via melatonin and alpha 2-adrenergic receptors in Xenopus laevis melanophores.
PubMed:Distribution of the Aplysia cardioexcitatory peptide, NdWFamide, in the central and peripheral nervous systems of Aplysia.
PubMed:Biomimetic entry to the sarpagan family of indole alkaloids: total synthesis of +-geissoschizine and +-N-methylvellosimine.
PubMed:Functional and molecular characteristics of system L in human breast cancer cells.
PubMed:Contryphan-Vn: a modulator of Ca2+-dependent K+ channels.
PubMed:Study of tryptophan enantiomer binding to a teicoplanin-based stationary phase using the perturbation technique. Investigation of the role of sodium perchlorate in solute retention and enantioselectivity.
PubMed:The chemical syntheses and bioactivities of novel peptide-based endothelin antagonists.
PubMed:Induction of anthranilate synthase activity by elicitors in oats.
PubMed:Transport of D-serine via the amino acid transporter ATB(0,+) expressed in the colon.
PubMed:Study of competitive binding of enantiomers to protein by affinity capillary electrochromatography.
PubMed:Contryphan-Vn: a novel peptide from the venom of the Mediterranean snail Conus ventricosus.
PubMed:Isotachophoresis separations of enantiomers on a planar chip with coupled separation channels.
PubMed:Body and intestinal growth of broiler chicks on a commercial starter diet. 3. Development and characteristics of tryptophan transport.
PubMed:Sweetener preference of C57BL/6ByJ and 129P3/J mice.
PubMed:Efficient asymmetric synthesis of biologically important tryptophan analogues via a palladium-mediated heteroannulation reaction.
PubMed:Fluorometric studies on inclusion complexation of L/D-tryptophan by beta-cyclodextrin 6-O-pyridinecarboxylates.
PubMed:Amino acid phosphoramidate monoesters of 3'-azido-3'-deoxythymidine: relationship between antiviral potency and intracellular metabolism.
PubMed:Contryphans from Conus textile venom ducts.
PubMed:4SR, a novel zinc-finger protein with SR-repeats, is expressed during early development of Xenopus.
PubMed:Metabolism of D-aminoacyl-tRNAs in Escherichia coli and Saccharomyces cerevisiae cells.
PubMed:General approach for the synthesis of sarpagine/ajmaline indole alkaloids. Stereospecific total synthesis of the sarpagine alkaloid (+)-vellosimine.
PubMed:Effect of tryptophan on the early tri-iodothyronine uptake in mouse thymocytes.
PubMed:Expression and purification of recombinant human indoleamine 2, 3-dioxygenase.
PubMed:Two syntheses of the 16- and 17-membered DEF ring systems of chloropeptin and complestatin.
PubMed:Enantiospecific total synthesis of the sarpagine related indole alkaloids talpinine and talcarpine as well as the improved total synthesis of alstonerine and anhydromacrosalhine-methine via the asymmetric Pictet-Spengler reaction.
PubMed:Efficiency of D-tryptophan as Niacin in rats.
PubMed:Yeast protease B-digested skimmed milk inhibits angiotensin-I-converting-enzyme activity.
PubMed:Electrophysiological evidence for a hyperpolarizing, galanin (1-15)-selective receptor on hippocampal CA3 pyramidal neurons.
PubMed:Crosslinking of imprinted proteases to maintain a tailor-made substrate selectivity in aqueous solutions.
PubMed:Solution structure of contryphan-R, a naturally occurring disulfide-bridged octapeptide containing D-tryptophan: comparison with protein loops.
PubMed:A novel D-leucine-containing Conus peptide: diverse conformational dynamics in the contryphan family.
PubMed:Study of a noncovalent trp repressor: DNA operator complex by electrospray ionization time-of-flight mass spectrometry.
PubMed:Enhanced responses of the chorda tympani nerve to nonsugar sweeteners in the diabetic db/db mouse.
PubMed:The contryphans, a D-tryptophan-containing family of Conus peptides: interconversion between conformers.
PubMed:First identification of autochthonous Cryptococcus neoformans var. gattii isloated from goats with predominantly severe pulmonary disease in Spain.
PubMed:Identification of a pituitary growth hormone-releasing peptide (GHRP) receptor subtype by photoaffinity labeling.
PubMed:Kynurenine pathway inhibition reduces neurotoxicity of HIV-1-infected macrophages.
PubMed:Imprinting of lyophilized alpha-chymotrypsin affects the reactivity of the active-site imidazole.
PubMed:Amino Acid Effects on Post-Stress Ulcers: Relationship to Brain Serotonin, 5-HIAA and Norepinephrine.
PubMed:Effect of mobile phase composition on the binding kinetics of chiral solutes on a protein-based high-performance liquid chromatography column: interactions of D- and L-tryptophan with immobilized human serum albumin.
PubMed:Changes in outward K+ currents in response to two types of sweeteners in sweet taste transduction of gerbil taste cells.
PubMed:Surface Monolayers of Poly(l-glutamic Acid)-Functionalized Amphiphiles: Effect of Attachment of Spiropyran to the Polymer Segment
PubMed:Selection of potent inhibitors of farnesyl-protein transferase from a synthetic tetrapeptide combinatorial library.
PubMed:Evolution of the sweetness receptor in primates. II. Gustatory responses of non-human primates to nine compounds known to be sweet in man.
PubMed:Contryphan is a D-tryptophan-containing Conus peptide.
PubMed:A modification of the N-terminal amino acid in the eremomycin aglycone.
PubMed:Endothelin receptor mediated constriction and dilatation in feline cerebral resistance arterioles in vivo.
PubMed:Synthesis and structure-activity relationships of 2-substituted D-tryptophan-containing peptidic endothelin receptor antagonists: importance of the C-2 substituent of the D-tryptophan residue for endothelin A and B receptor subtype selectivity.
PubMed:Induction of the d-Amino Acid Oxidase from Trigonopsis variabilis.
PubMed:Schistosoma mansoni: evidence for a 28-kDa membrane-anchored protease on schistosomula.
PubMed:Tryptophanase-catalysed degradation of D-tryptophan in highly concentrated diammonium hydrogen phosphate solution.
PubMed:Role of binding capacity versus binding strength in the separation of chiral compounds on protein-based high-performance liquid chromatography columns. Interactions of D- and L-tryptophan with human serum albumin.
PubMed:Cryptococcus neoformans var. gattii can be separated from var. neoformans by its ability to assimilate D-tryptophan.
PubMed:Investigation of the chemosensory function of amphids of Syngamus trachea using electrophysiological techniques.
PubMed:Hexarelin, a novel GHRP-6 analog, counteracts the inhibitory effect of hydrocortisone on growth hormone secretion in acromegaly.
PubMed:Solution conformational dynamics of the C-terminal residues in endothelin-1 and some analogues: a time-resolved fluorescence study.
PubMed:Kinetic characterization of a carrier-mediated transport system for L-tryptophan in human blood platelets.
PubMed:Structural features of L-tryptophan required for activation of TRAP, the trp RNA-binding attenuation protein of Bacillus subtilis.
PubMed:Detection of water proximity to tryptophan residues in proteins by single photon radioluminescence.
PubMed:Sequential gonadotrophin-releasing hormone agonist/low-dose oral contraceptive treatment for leiomyomata uteri.
PubMed:Tryptophan 2,3-dioxygenase in Saccharomyces cerevisiae.
PubMed:Stereospecific effects of intraduodenal tryptophan on pyloric and duodenal motility in humans.
PubMed:Attempted protection of spermatogenesis from irradiation in patients with seminoma by D-Tryptophan-6 luteinizing hormone releasing hormone.
PubMed:The role of insulin in ovarian size in patients with the polycystic ovary syndrome.
PubMed:Effect of modulators of the adenylate cyclase system on sweet electrophysiological taste responses in gerbil.
PubMed:Stimulation of erythropoiesis by the non-steroidal anti-androgen nilutamide in men with prostate cancer: evidence for an agonistic effect?
PubMed:Synthesis and spectral characterization of 5'-phosphopyridoxyl-D,L-7-azatryptophan, a photophysical probe of protein structure and dynamics.
PubMed:Amino acid N-malonyltransferases from mung beans. Action on 1-aminocyclopropane-1-carboxylic acid and D-phenylalanine.
PubMed:Enhancement of murine gustatory neural responses to D-amino acids by saccharin.
PubMed:Study of a reagent- and mediator-less biosensor for D-amino acids based on co-immobilized D-amino acid oxidase and peroxidase in carbon paste electrodes.
PubMed:Synthesis and biological evaluation of cholecystokinin analogs in which the Asp-Phe-NH2 moiety has been replaced by a 3-amino-7-phenylheptanoic acid or a 3-amino-6-(phenyloxy)hexanoic acid.
PubMed:Characterization of the binding and chiral separation of D- and L-tryptophan on a high-performance immobilized human serum albumin column.
PubMed:Another look at co-treatment with growth hormone and human menopausal gonadotrophins in poor ovarian responders.
PubMed:Lysine 87 in the beta subunit of tryptophan synthase that forms an internal aldimine with pyridoxal phosphate serves critical roles in transimination, catalysis, and product release.
PubMed:Unexpected antinociceptive potency of cyclic [D-Tca1]CTAP: potential for a novel mechanism of action.
PubMed:Bioavailable level and source of cysteine determine protein quality of a commercial enteral product: adequacy of tryptophan but deficiency of cysteine for rats fed an enteral product prepared fresh or stored beyond shelf life.
PubMed:Peptidoglycan tripeptide content and cross-linking are altered in Enterobacter cloacae induced to produce AmpC beta-lactamase by glycine and D-amino acids.
PubMed:Purification and characterization of anthranilate synthase from Catharanthus roseus.
PubMed:Genetically variable taste sensitivity to D-amino acids in mice.
PubMed:Studies on neurokinin antagonists. 1. The design of novel tripeptides possessing the glutaminyl-D-tryptophylphenylalanine sequence as substance P antagonists.
PubMed:Subunit communication in the tryptophan synthase alpha 2 beta 2 complex. Effects of beta subunit ligands on proteolytic cleavage of a flexible loop in the alpha subunit.
PubMed:Biosynthesis of pyrrolnitrin. Incorporation of 13C, 15N double-labelled D- and L-tryptophan.
PubMed:NMR studies of the activation of the Escherichia coli trp repressor.
PubMed:Role of D-tryptophan for affinity of MEN 10207 tachykinin antagonist at NK2 receptors.
PubMed:Some pharmacological properties of cyclic and linear analogs obtained by substituting each residue of an oxytocin antagonist with D-tryptophan.
PubMed:Synthesis and biological activity of 2-phenylethyl ester analogues of C-terminal heptapeptide of cholecystokinin modified in Trp 30 region.
PubMed:Tryptophan protects human melanoma cells against gamma-interferon and tumour necrosis factor-alpha: a unifying mechanism of action.
PubMed:Biosynthesis of indole-3-acetic acid in tomato shoots: Measurement, mass-spectral identification and incorporation of (-2)H from (-2)H 2O into indole-3-acetic acid, D- and L-tryptophan, indole-3-pyruvate and tryptamine.
PubMed:Bradykinin agonist activity of a novel, potent oxytocin antagonist.
PubMed:Stable Isotope Labeling, in Vivo, of d- and l-Tryptophan Pools in Lemna gibba and the Low Incorporation of Label into Indole-3-Acetic Acid.
PubMed:Design of potent oxytocin antagonists featuring D-tryptophan at position 2.
PubMed:Effect of D-amino acids on Escherichia coli strains with impaired penicillin-binding proteins.
PubMed:[Structure-activity relationship of cystokinins: analogs exhibiting selective activity].
PubMed:Purification and characterisation of an extracellular serine proteinase from Aspergillus fumigatus and its detection in tissue.
PubMed:In vivo neurochemical and behavioural effects of intracerebrally administered neurotensin and D-Trp11-neurotensin on mesolimbic and nigrostriatal dopaminergic function in the rat.
PubMed:Cyclic hexapeptides related to somatostatin. Conformational analysis employing 1H-NMR and molecular dynamics.
PubMed:Spantide II, a novel tachykinin antagonist having high potency and low histamine-releasing effect.
PubMed:Transport of benzenoid amino acids by system T and four broad scope systems in preimplantation mouse conceptuses.
PubMed:Inhibitors of human renin. Cyclic peptide analogues containing a D-Phe-Lys-D-Trp sequence.
PubMed:Correlation between follicular fluid content and the results of in vitro fertilization and embryo transfer. III. Proteoglycans.
PubMed:Antagonism of the gerbil's sweetener and Polycose gustatory responses by copper chloride.
PubMed:Studies on the crystal structure of A1-(D-Tryptophan) insulin.
PubMed:Regression of nitrosamine-induced pancreatic cancers in hamsters treated with luteinizing hormone-releasing hormone antagonists or agonists.
PubMed:Synthesis and biological activity of NK-2 selective tachykinin antagonists containing D-tryptophan.
PubMed:A highly selective NK-2 tachykinin receptor antagonist containing D-tryptophan.
PubMed:Cytotoxicity of S-(1,2,3,4,4-pentachlorobutadienyl)-L cysteine after apical and basolateral exposure of LLC-PK monolayers. Involvement of an amino acid transport system.
PubMed:Separate and shared lysosomal transport of branched and aromatic dipolar amino acids.
PubMed:Carrier-Mediated Uptake of 1-(Malonylamino)cyclopropane-1-Carboxylic Acid in Vacuoles Isolated from Catharanthus roseus Cells.
PubMed:Effect of D-tryptophan-6-luteinizing hormone-releasing hormone on the tumoral growth and plasma sex steroid levels in cirrhotic patients with hepatocellular carcinoma.
PubMed:Inhibition of tumor cell growth by interferon-gamma is mediated by two distinct mechanisms dependent upon oxygen tension: induction of tryptophan degradation and depletion of intracellular nicotinamide adenine dinucleotide.
PubMed:A new D-stereospecific amino acid amidase from Ochrobactrum anthropi.
PubMed:Enzyme kinetic and spectroscopic studies of inhibitor and effector interactions with indoleamine 2,3-dioxygenase. 2. Evidence for the existence of another binding site in the enzyme for indole derivative effectors.
PubMed:Enzyme kinetic and spectroscopic studies of inhibitor and effector interactions with indoleamine 2,3-dioxygenase. 1. Norharman and 4-phenylimidazole binding to the enzyme as inhibitors and heme ligands.
PubMed:Tryptophan 2,3-dioxygenase activity in rat skin.
PubMed:Application of rapid-scanning, stopped-flow spectroscopy to the characterization of intermediates formed in the reactions of L- and D-tryptophan and beta-mercaptoethanol with Escherichia coli tryptophan synthase.
PubMed:Programmed cell death (apoptosis) in pancreatic cancers of hamsters after treatment with analogs of both luteinizing hormone-releasing hormone and somatostatin.
PubMed:The roles of superoxide anion and methylene blue in the reductive activation of indoleamine 2,3-dioxygenase by ascorbic acid or by xanthine oxidase-hypoxanthine.
PubMed:Specific [(3)H]tryptophan binding sites in rat brain.
PubMed:Physiological control of amonabactin biosynthesis in Aeromonas hydrophila.
PubMed:Tyrosine phenol-lyase from Citrobacter intermedius. Factors controlling substrate specificity.
PubMed:2-Phenylethyl ester and 2-phenylethyl amide derivative analogues of the C-terminal hepta- and octapeptide of cholecystokinin.
PubMed:Identification of l-Tryptophan as an Endogenous Inhibitor of Embryo Germination in White Wheat.
PubMed:Evidence that glutamic acid 49 of tryptophan synthase alpha subunit is a catalytic residue. Inactive mutant proteins substituted at position 49 bind ligands and transmit ligand-dependent to the beta subunit.
PubMed:Substrate specificity of duckling hepatic and renal D-amino acid oxidase.
PubMed:Protective effects of analogs of luteinizing hormone-releasing hormone against chemotherapy-induced testicular damage in rats.
PubMed:Design of potent cyclic gonadotropin releasing hormone antagonists.
PubMed:Influence of proteinase inhibitors and substrates on 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-binding capacity of the rat hepatic Ah receptor.
PubMed:Some N-acyl-D-amino acid derivatives having antibotulinal properties.
PubMed:Soft agar colony formation of bladder cells during carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine and application to detection of bladder cancer promoters.
PubMed:Superactive octapeptide somatostatin analogs containing tryptophan at position 1.
PubMed:Protective effects of analogs of luteinizing hormone-releasing hormone against x-radiation-induced testicular damage in rats.
PubMed:Treatment of nitrosamine-induced pancreatic tumors in hamsters with analogs of somatostatin and luteinizing hormone-releasing hormone.
PubMed:Histological findings in the rat prostate cancer model during treatment with a luteinizing hormone-releasing hormone agonist and novantrone.
PubMed:Two distinct types of mutations conferring to Escherichia coli K12 capability of D-tryptophan utilization.
PubMed:Mutagenicities of indole and 30 derivatives after nitrite treatment.
PubMed:Combination of a long-acting delivery system for luteinizing hormone-releasing hormone agonist with Novantrone chemotherapy: increased efficacy in the rat prostate cancer model.
PubMed:Purification and characterization of a novel enzyme, N-carbamoylsarcosine amidohydrolase, from Pseudomonas putida 77.
PubMed:Release and characterization of cholecystokinin from isolated canine jejunal cells.
PubMed:Isomerization of (3S)-2,3-dihydro-5-fluoro-L-tryptophan and of 5-fluoro-L-tryptophan catalyzed by tryptophan synthase: studies using fluorine-19 nuclear magnetic resonance and difference spectroscopy.
PubMed:Beta-elimination of indole from L-tryptophan catalyzed by bacterial tryptophan synthase: a comparison between reactions catalyzed by tryptophanase and tryptophan synthase.
PubMed:Caffeine intensifies taste of certain sweeteners: role of adenosine receptor.
PubMed:Utilization of isomers and analogs of amino acids and other sulfur-containing compounds.
PubMed:Suppression of testicular androgenesis by D-tryptophan-6-luteinizing hormone-releasing hormone does not affect TSH secretion in male subjects.
PubMed:Kidney clearance of D- and L-tryptophan by rats.
PubMed:[Action of [3,14-L-selenocysteine, 8-D-tryptophan]-somatostatin on insulin and glucagon secretion of the isolated perfused pancrease of the Wistar rat].
PubMed:[Effect of the exogenous tryptophan on biosynthesis of ergot alkaloids in Penicillium sizovae].
PubMed:The growth of single crystal and the determination of crystallographic parameters of (L-tryptophan)A1-insulin and (D-tryptophan)A1-insulin.
PubMed:Tryptophan transport through transport system T in the human erythrocyte, the Ehrlich cell and the rat intestine.
PubMed:Separation and purification of enzymes by continuous pH-parametric pumping.
PubMed:Human indolylamine 2,3-dioxygenase. Its tissue distribution, and characterization of the placental enzyme.
PubMed:Photoinactivation and photoaffinity labeling of tryptophan synthase alpha 2 beta 2 complex by the product analogue 6-azido-L-tryptophan.
PubMed:Effects of gymnemic acid on the chorda tympani proper nerve responses to sweet, sour, salty and bitter taste stimuli in the chimpanzee.
PubMed:Synthesis and biological activities of analogues of angiotensins II and III containing O-methyltyrosine and D-tryptophan.
PubMed:D-Tryptophan-6 analog of luteinizing hormone-releasing hormone as a protective agent against testicular damage caused by cyclophosphamide in baboons.
PubMed:Combination of long-acting microcapsules of the D-tryptophan-6 analog of luteinizing hormone-releasing hormone with chemotherapy: investigation in the rat prostate cancer model.
PubMed:Radioimmunoassay for 6-D-tryptophan analog of luteinizing hormone-releasing hormone: measurement of serum levels after administration of long-acting microcapsule formulations.
PubMed:Nutritive value of D-tryptophan for the growing pig.
PubMed:Inhibition of growth of a prolactin and growth hormone-secreting pituitary tumor in rats by D-tryptophan-6 analog of luteinizing hormone-releasing hormone.
PubMed:Experimental protection by a luteinizing hormone-releasing hormone agonist of a bone marrow nitrosourea aplasia. Preliminary observations.
PubMed:N-malonyltransferases from peanut.
PubMed:Effect of D-tryptophan on hemolysin production in Vibrio parahaemolyticus.
PubMed:A substance P antagonist not containing D-tryptophan.
PubMed:Biological evaluation of substance P antagonists.
PubMed:Long-acting delivery systems for peptides: inhibition of rat prostate tumors by controlled release of [D-Trp6]luteinizing hormone-releasing hormone from injectable microcapsules.
PubMed:Antihypertensive effects of L-tryptophan are not mediated by brain serotonin.
PubMed:Structure-function studies of N-acyl derivatives of tryptophan that function as specific cholecystokinin receptor antagonists.
PubMed:Human skin chymotryptic proteinase. Isolation and relation to cathepsin g and rat mast cell proteinase I.
PubMed:Synthesis of [1, 6-cyclo (acetyl-1-L-glutamic acid, 2-D-phenylalanine, 3-D-tryptophan, 6-D-lysine)] luteinizing hormone-releasing hormone on poly-N-acrylylpyrrolidine resin.
PubMed:L-Isoleucine and L-leucine are promoters of bladder cancer in rats.
PubMed:Utilization of D- and L-tryptophan by the growing dog.
PubMed:Detection of amino acids as possible promoters of bladder cancer in rats by measuring their enhancement of agglutination of bladder cells by concanavalin A.
PubMed:[Synthesis of cyclo-[des(1,2-L-alanyl-glycine, 14-L-cysteine)-3-s-carboxymethyl-L-homocysteinamid, 8-D-tryptophan]-somatostatin].
PubMed:Two-step interaction of alpha-chymotrypsin with a fluorescent inhibitor. A dynamic study by the temperature-jump method.
PubMed:[Exchange of A1-glycine in bovine insulin with L- and D-tryptophan].
PubMed:Production of the Kanagawa hemolysin by Vibrio parahaemolyticus in a synthetic medium.
PubMed:Separation of free and chymotrypsin-bound alpha 2-macroglobulin by affinity chromatography. Its use to demonstrate that the two chymotrypsin-binding sites of alpha 2-macroglobulin are equivalent and independent.
PubMed:Pressure dependence of trypsin-catalyzed hydrolyses of specific substrates.
PubMed:Differential effects of amino acids on the period of the circadian rhythm from the Aplysia eye.
PubMed:Metabolism of Tryptophan, Indole-3-acetic Acid, and Related Compounds in Parasitic Plants from the Genus Orobanche.
PubMed:D-Tryptophan-6-luteinizing hormone-releasing hormone in the treatment of normogonadotropic oligoasthenozoospermia.
PubMed:The mechanism of tryptophan binding to tryptophan synthase from Escherichia coli.
PubMed:Suppression of androgen production by D-tryptophan-6-luteinizing hormone-releasing hormone in man.
PubMed:Failure to interrupt established pregnancy in humans by D-tryptophan-6-luteinizing hormone-releasing hormone.
PubMed:D-tryptophan-6-LH-RH-at los doses in the treatment of male subfertility.
PubMed:Stimulation of the gerbil's gustatory receptors by artificial sweeteners.
PubMed:Transition state affinity jump chromatography. A double selection method for isolating catalytically active enzymes and other molecules.
PubMed:Dipsogenic effect of L-5-hydroxytryptophan in rats.
PubMed:Stereospecificity of hepatic L-tryptophan 2,3-dioxygenase.
PubMed:L-Tryptophan transport in human red blood cells.
PubMed:Purification and characterization of yeast protease B.
PubMed:Inversion of D-tryptophan to L-tryptophan and excretory patterns in the rat and chick.
PubMed:Comparison of the nutritive values of L-, DL- and D-tryptophan in the rat and chick.
PubMed:The effects of exogenous nutrients on growth of chick embryo brain.
PubMed:Wave Forms of Caenorhabditis elegans in a Chemical Attractant and Repellent and in Thermal Gradients.
PubMed:Qualitative differences among sweeteners.
PubMed:Immobilization and characterization of D-amino acid oxidase.
PubMed:Inhibition of alpha-chymotrypsin by D-tryptophan amide covalently bound to macromolecular carriers: specific, steric, and electrostatic effects.
PubMed:Nutritive value of L-, DL- and D-tryptophan in the chick.
PubMed:Biodistribution studies of labeled tryptophan: a potential pancreas-scanning agent.
PubMed:Effect of tryptophan analogs on derepression of the Escherichia coli tryptophan operon by indole-3-propionic acid.
PubMed:Utilization of D-amino acids by dadR mutants of Salmonella typhimurium.
PubMed:Opiate-like naloxone-reversible actions of somatostatin given intracerebrally.
PubMed:Microcalorimetric method to determine competitive binding. Action of a psychotropic drug (dipotassium chlorazepate) on L-tryptophan . human serum albumin complex.
PubMed:The stimulating effect of fatty acids and amino acid derivatives on the labellar sugar receptor of the fleshfly.
PubMed:Preparative purification of the rat mast cell chymase: characterization and interaction with granule components.
PubMed:Detection of antimetabolite activity: effects and transport of tryptophan analogs in Escherichia coli.
PubMed:Evolutionary significance of the system utilizing D-amino acid enantiomers.
PubMed:Mutagenicities of protein pyrolysates.
PubMed:Crystalline hemoprotein from Pseudomonas that catalyzes oxidation of side chain of tryptophan and other indole derivatives.
PubMed:Chemotactic responses of male Caenorhabditis elegans.
PubMed:Interaction of human interferons with immobilized hydrophobic amino acids and dipeptides.
PubMed:A comparison of D and L-tryptophan on the cerebral metabolism of 5-hydroxytryptamine and dopamine in the dog.
PubMed:Metabolism of D- and L-tryptophan in dogs.
PubMed:Role of D-tryptophan oxidase in D-tryptophan utilization by Escherichia coli.
PubMed:Absorption of circularly polarized gamma-radiation in L- and D-amino acids.
PubMed:Effects of essential and nonessential amino acids on gastric emptying in the dog.
PubMed:The avoidance of D-tryptophan by the nematode Caenorhabditis elegans.
PubMed:Non-specific binding in the affinity chromatography of chymotrypsin.
PubMed:Insensitivity of D-amino acid dehydrogenase synthesis to catabolic repression in dadR mutants of Salmonella typhimurium.
PubMed:Tryptophan catabolism in Bacillus megaterium.
PubMed:Isolation and identification of indole-3-carboxaldehyde: a major new urinary metabolite of D-tryptophan.
PubMed:Dissimilation of tryptophan and related indolic compounds by ruminal microorganisms in vitro.
PubMed:Enzymatic conversion of L- and D-tryptophan to kynurenine by rat liver.
PubMed:Properties of an Aminotransferase of Pea (Pisum sativum L.).
PubMed:Tryptophan 5-hydroxylase in rat intestine.
PubMed:Renal excretion of D-tryptophan, 5-hydroxytryptamine, and 5-hydroxyindoleacetic acid in rats.
PubMed:The effect of D-tryptophan upon induced beta-galactosidase synthesis in Escherichia coli.
PubMed:D-Tryptophan pyrrolase activity in the liver and the intestine of the rat.
PubMed:[D-tryptophan metabolism in Flavobacterium butyri 331].
PubMed:Magnetic resonance studies of protein-small molecule interactions. Dynamics of binding between N-trifluoroacetyl-D-tryptophan and -chymotrypsin.
PubMed:[Transformation of D-tryptophan into L-tryptophan by Flavobacterium butyri 331].
PubMed:Conversion of D-tryptophan to nicotinic acid in the rat.
PubMed:Mutant strains of Escherichia coli K12 that use D-amino acids.
PubMed:Inversion in the metabolism of D-tryptophan in the rabbit and the rat.
PubMed:L-tryptophan. A non-allosteric organ-specific uncompetitive inhibitor of human placental alkaline phosphatase.
PubMed:The Conversion of d-Tryptophan to l-Tryptophan in Cell Cultures of Tobacco.
PubMed:Production of D-kynurenine and other metabolites from D-tryptophan by the intact rabbit and by rabbit tissue.
PubMed:[S-shape character of the relation of the initial reaction rate to substrate concentration during inhibition by N-acetyl-D-tryptophan of the hydrolysis of ethyl aceturate by alpha-chymotrypsin].
PubMed:N-Malonyl-d-tryptophan in Apple Fruits Treated with Succinic Acid 2,2-Dimethylhydrazide.
PubMed:Regulation of enzymes involved in the conversion of tryptophan to nicotinamide adenine dinucleotide in a colorless strain of Xanthomonas pruni.
PubMed:Calorimetric investigations of the binding of inhibitors to alpha-chymotrypsin. I. The enthalpy of dilution of alpha-chymotrypsin and of proflavin, and the enthalpy of binding of indole, N-acetyl-D-tryptophan, and proflavin to alpha-chymotrypsin.
PubMed:The binding of inhibitors to alpha-chymotrypsin at alkaline pH.
PubMed:Enzymic formation of D-kynurenine from D-tryptophan.
PubMed:Metabolism of D-tryptophan by a species of Flavobacterium.
PubMed:The binding of inhibitors to alpha-chymotrypsin.
PubMed:ACTION OF D-TRYPTOPHAN ON E. COLI.
PubMed:[N-ACETYLATION OF D-TRYPTOPHAN BY SACCHAROMYCES GENERA].
PubMed:FACTORS AFFECTING THE INTRACELLULAR SYNTHESIS OF KYNURENINE.
PubMed:Conversion of D-tryptophan to L-tryptophan by cell extracts of a Flavobacterium species.
PubMed:Regulation of early reactions in the biosynthesis of tryptophan in Neurospora crassa.
PubMed:Microbial oxidation of D-tryptophan.
PubMed:Effect of L-tryptophan on diuresis and 5-hydroxyindoleacetic acid excretion in the rat.
PubMed:A new pathway of D-tryptophan metabolism: enzymic formation of kynurenic acid via D-kynurenine.
PubMed:Repression and inhibition of indole-synthesizing activity in Neurospora crassa.
PubMed:[Atypical behavior of 2 male mice of the Swiss strain in regard to the utilization of D-tryptophan].
PubMed:[Comparison of the supplementary effects of L and D tryptophan with diets complete from the vitamin point of view or deficient in pyridoxine and riboflavine. Test of the growth of the white mouse].
PubMed:[Role of pyridoxine in the metabolism of L- and D-tryptophan. Comparison of the effects of direct and isoniazid-induced B6 avitaminosis].
PubMed:Quantitative studies on human urinary metabolites of D-, DL-, acetyl-L-, and acetyl-D-tryptophan.
PubMed:Utilization of D-tryptophan by the chick.
PubMed:[Comparative influence of B6 deficiency and of isoniazide on metabolism of L-tryptophan and D-tryptophan in the white rat].
PubMed:Metabolism of D-tryptophan in the normal human subject.
PubMed:The fate of ingested acetyl-L- and D-tryptophan in the human subject.
PubMed:The conversion of L-and D-tryptophan to niacin in human body.
PubMed:Nitrogen balance of adult rats fed amino acid diets low in L-, DL- and D-tryptophan.
PubMed:The availability of D-histidine, related imidazoles, and D-tryptophan in the mouse.
PubMed:Inhibition of crown-gall bacteria by D-tryptophan and its reversal by an unidentified metabolite.
PubMed:The biological value of corn and wheat proteins in the male infant, with a note on the utilization of D-tryptophan.
PubMed:The effect of D-tryptophan on the utilization of the L isomer by some lactic acid bacteria.
 
Notes:
Tryptophan (IUPAC-IUBMB abbreviation: Trp or W; IUPAC abbreviation: L-Trp or D-Trp; sold for medical use as Tryptan) is one of the 20 standard amino acids, as well as an essential amino acid in the human diet. It is encoded in the standard genetic code as the codon UGG. the D-stereoisomer is occasionally found in naturally produced peptides (for example, the marine venom peptide contryphan). The distinguishing structural characteristic of tryptophan is that it contains an indole functional group. It is an essential amino acid as defined by its growth effects on rats. [HMDB]
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