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dextro-trehalose dihydrate
2-(hydroxymethyl)-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol dihydrate

Supplier Sponsors

CAS Number: 6138-23-4Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:202-739-6
FDA UNII: 7YIN7J07X4
Beilstein Number:5322018
MDL:MFCD00071594
Molecular Weight:378.32882000
Formula:C12 H26 O13
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:sweeteners, flavor enhancers
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 45 Trehalose View - notice PDF
JECFA Food Additive: Trehalose
FEMA Number:4600 trehalose, dihydrate
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):6138-23-4 ; TREHALOSE, DIHYDRATE
 
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: Yes
Boiling Point: 808.00 to 810.00 °C. @ 760.00 mm Hg
Flash Point: 829.00 °F. TCC ( 442.78 °C. )
Soluble in:
 alcohol, slightly
 water
 water, 58.66 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
a,a-D-Trehalose dihydrate endotoxin free
Carbosynth
For experimental / research use only.
a,a-D-Trehalose dihydrate
Charkit Chemical
TREHALOSE DIHYDRATE
ECSA Chemicals
TREHALOSE
ECSA TRADE THE MOST UPDATED FINANCIAL PUBLICATION ON THE WORLD OF CHEMISTRY
EMD Millipore
For experimental / research use only.
Trehalose, Dihydrate
ExtraSynthese
For experimental / research use only.
Trehalose
Glentham Life Sciences
D-(+)-Trehalose dihydrate, Ph. Eur. grade
Glentham Life Sciences
D-(+)-Trehalose dihydrate
Indis NV
For experimental / research use only.
Trehalose Dihydrate
Jiangyin Healthway
Trehalose
New functional food ingredients
Jiangyin Healthway
Trehalose
Matrix Scientific
For experimental / research use only.
D-(+)-Trehalose dihydrate, 95+%
Penta International
D-(+)-TREHALOSE DIHYDRATE
Pfanstiehl, Inc
a,a – Trehalose Dihydrate, High Purity (Low Endotoxin), USP/NF, EP, JP, ChP
Odor: characteristic
Use: Trehalose is a non-reducing disaccharide consisting of two glucose molecules linked by an a, a–1,1 bond. Pfanstiehl Brand, High Purity Low Endotoxin Trehalose is used in the biopharmaceutical industry to stabilize proteins, lipids, and carbohydrates throughout the formulation and freeze/thaw life cycle of therapeutics. It is also widely applied as a key component in cryopreservation/freeze media to stabilize cell membranes and improve the recovery and robustness of cells used for bioproduction and cell therapy.
Santa Cruz Biotechnology
For experimental / research use only.
Trehalose Dihydrate 98%
Sigma-Aldrich: Sigma
For experimental / research use only.
D-(+)-Trehalose dihydrate from Saccharomyces cerevisiae, ≥99%
Spec-Chem Industry
SpecKare TM TRHL(Trehalose)
TCI AMERICA
For experimental / research use only.
D-(+)-Trehalose Dihydrate >98.0%(GC)
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
sweeteners, flavor enhancers
Recommendation for dextro-trehalose dihydrate usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 24
Click here to view publication 24
 average usual ppmaverage maximum ppm
baked goods: 20000.0000050000.00000
beverages(nonalcoholic): 20000.0000035000.00000
beverages(alcoholic): 1000.0000010000.00000
breakfast cereal: 15000.0000030000.00000
cheese: 3000.0000050000.00000
chewing gum: 20000.0000035000.00000
condiments / relishes: 20000.0000050000.00000
confectionery froastings: 20000.0000050000.00000
egg products: 15000.0000040000.00000
fats / oils: 15000.0000040000.00000
fish products: 15000.0000050000.00000
frozen dairy: 15000.0000050000.00000
fruit ices: 10000.0000050000.00000
gelatins / puddings: 50000.0000050000.00000
granulated sugar: --
gravies: 20000.0000050000.00000
hard candy: 50000.0000050000.00000
imitation dairy: 20000.0000050000.00000
instant coffee / tea: 10000.0000030000.00000
jams / jellies: 50000.0000050000.00000
meat products: 15000.0000050000.00000
milk products: 20000.0000050000.00000
nut products: 20000.0000050000.00000
other grains: 15000.0000030000.00000
poultry: 15000.0000050000.00000
processed fruits: 10000.0000030000.00000
processed vegetables: 35000.0000050000.00000
reconstituted vegetables: 15000.0000030000.00000
seasonings / flavors: 20000.0000050000.00000
snack foods: 20000.0000050000.00000
soft candy: 50000.0000050000.00000
soups: 20000.0000050000.00000
sugar substitutes: --
sweet sauces: 50000.0000050000.00000
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :181978
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
2-(hydroxymethyl)-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol dihydrate
Chemidplus:0006138234
RTECS:LZ5776547 for cas# 6138-23-4
 
References:
 2-(hydroxymethyl)-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol dihydrate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):181978
Pubchem (sid):135158900
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
CHEMBL:View
Metabolomics Database:Search
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2940.00.0000
FDA Listing of Food Additive Status:View
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
a-D-glucopyranoside, a-D-glucopyranosyl, hydrate (1:2)
1-O-alpha-D-glucopyranosyl-alpha-dextro-glucopyranoside
1-O-alpha-dextro-glucopyranosyl-alpha-dextro-glucopyranoside
2-(hydroxymethyl)-6-(3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl)oxyoxane-3,4,5-triol dihydrate
2-(hydroxymethyl)-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol dihydrate
D-trehalose dihydrate
D-(+)-trehalose dihydrate
 trehalose, dihydrate
 
 
Notes:
None found
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