EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dextro-serine
ethanaminium, 1-carboxy-2-hydroxy-, inner salt, (1R)-

Supplier Sponsors

CAS Number: 312-84-5Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:206-229-4
FDA UNII: 1K77H2Z9B1
Nikkaji Web:J1.196G
Beilstein Number:1721403
MDL:MFCD00004269
XlogP3:-3.10 (est)
Molecular Weight:105.09339000
Formula:C3 H7 N O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 229.00 °C. @ 760.00 mm Hg
Boiling Point: 394.82 °C. @ 760.00 mm Hg (est)
Flash Point: 379.00 °F. TCC ( 192.60 °C. ) (est)
logP (o/w): -1.490 (est)
Soluble in:
 water, 3.64E+05 mg/L @ 20 °C (exp)
 water, 4.02e+005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Cycloserine Impurity 1 > 95%
Odor: characteristic
Use: D-Serine is a proteinogenic amino acids involved in the biosynthesis of purines and pyrimidines. It is a inhibitor of serine palmitoyltransferase. It is also a neuromodulator.
Changzhou Longo Chemical
D-Serine
Glentham Life Sciences
D-Serine
Penta International
D-SERINE
Sigma-Aldrich: Sigma
For experimental / research use only.
D-Serine ≥98% (TLC)
TCI AMERICA
For experimental / research use only.
D-Serine >98.5%(T)
Universal Preserv-A-Chem Inc.
D-SERINE
Odor: characteristic
Use: D-Serine is an amino acid found in the brain. Derived from Glycine, d-serine is a neuromodulator, meaning it regulates the activities of neurons.
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
information only not used for fragrances or flavors
Recommendation for dextro-serine usage levels up to:
 not for fragrance use.
 
Recommendation for dextro-serine flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
ClinicalTrials.gov:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):312-84-5
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :71077
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(2R)-2-amino-3-hydroxypropanoic acid
Chemidplus:0000312845
 
References:
 (2R)-2-amino-3-hydroxypropanoic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):71077
Pubchem (sid):135028206
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
KEGG (GenomeNet):C00740
HMDB (The Human Metabolome Database):HMDB03406
FooDB:FDB023164
YMDB (Yeast Metabolome Database):YMDB00284
Export Tariff Code:2922.50.5000
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 antistatic agents
 humectants
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
(R)-2-amino-3-hydroxy-propionic acid
(2R)-2-amino-3-hydroxypropanoic acid
(R)-2-amino-3-hydroxypropanoic acid
D-2-amino-3-hydroxypropanoic acid
(R)-2-amino-3-hydroxypropionic acid
D-2-amino-3-hydroxypropionic acid
R(-)-2-amino-3-hydroxypropionic acid
 ethanaminium, 1-carboxy-2-hydroxy-, inner salt, (1R)-
D-serin
(R)-serine
D-serine
D-(-)-serine
 serine D-
 serine, D-
 

Articles:

PubMed:Biosensors for D-amino acid detection.
PubMed:D-amino acid formation in sterilized alkali-treated olives.
PubMed:The presence of high concentrations of free D-amino acids in human saliva.
PubMed:The neurotransmitters glycine and GABA stimulate glucagon-like peptide-1 release from the GLUTag cell line.
PubMed:Gas chromatographic quantification of free D-amino acids in higher vertebrates.
PubMed:Optimized, one-step, recovery-enrichment broth for enhanced detection of Listeria monocytogenes in pasteurized milk and hot dogs.
PubMed:Vancomycin-resistant enterococci: recent advances in genetics, epidemiology and therapeutic options.
PubMed:Optimizing detection of heat-injured Listeria monocytogenes in pasteurized milk.
PubMed:Development of a simple recovery-enrichment system for enhanced detection of heat-injured Listeria monocytogenes in pasteurized milk.
PubMed:Chemistry, nutrition, and microbiology of D-amino acids.
PubMed:Changes of amino acid composition and lysinoalanine formation in alkali-pickled duck eggs.
PubMed:Lack of attenuation of valproic acid-induced embryotoxicity by compounds involved in one-carbon transfer reactions.
PubMed:Induction of feeding by 7-chlorokynurenic acid, a strychnine-insensitive glycine binding site antagonist.
PubMed:Formation, nutritional value, and safety of D-amino acids.
PubMed:Protein-alkali reactions: chemistry, toxicology, and nutritional consequences.
 
Notes:
A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines, pyrimidines, and other amino acids. As a constituent (residue) of proteins, its side chain can undergo O-linked glycosylation. This might be important in explaining some of the devastating consequences of diabetes. It is one of three amino acid residues that are commonly phosphorylated by kinases during cell signalling in eukaryotes. Phosphorylated serine residues are often referred to as phosphoserine. Serine proteases are a common type of protease. Serine (IPA [sejin]), organic compound, one of the 20 amino acids commonly found in animal proteins. Only the L-stereoisomer appears in mammalian protein. It is not essential to the human diet, since it can be synthesized in the body from other metabolites, including glycine. Serine was first obtained from silk protein, a particularly rich source, in 1865. Its name is derived from the Latin for silk, sericum. Serine's structure was established in 1902. [HMDB]
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