EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

dextro-pipecolinic acid
2-piperidinecarboxylic acid, (2R)-

Supplier Sponsors

CAS Number: 1723-00-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:217-024-4
Nikkaji Web:J203.118C
Beilstein Number:4291592
XlogP3:-2.30 (est)
Molecular Weight:129.15907000
Formula:C6 H11 N O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 265.80 °C. @ 760.00 mm Hg (est)
Flash Point: 238.00 °F. TCC ( 114.50 °C. ) (est)
Soluble in:
 water, 7.406e+004 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
None found
BOC Sciences
For experimental / research use only.
D-(+)-Pipercolic acid 95%
Matrix Scientific
For experimental / research use only.
(R)-Piperidine-2-carboxylic acid, 95+%
Santa Cruz Biotechnology
For experimental / research use only.
D-Pipecolinic Acid
Sigma-Aldrich: Aldrich
For experimental / research use only.
D-Pipecolinic Acid 99%
For experimental / research use only.
D-Pipecolinic Acid >98.0%(T)
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
natural substances and extractives
Recommendation for dextro-pipecolinic acid usage levels up to:
 not for fragrance use.
Recommendation for dextro-pipecolinic acid flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :736316
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(2R)-piperidine-2-carboxylic acid
 (2R)-piperidine-2-carboxylic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):736316
Pubchem (sid):135060178
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):HMDB05960
YMDB (Yeast Metabolome Database):YMDB01675
Export Tariff Code:2933.39.9100
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 found in nature
(R)-(-)-nipecotic acid
(R)-pipecolic acid
D-pipecolic acid
D-(+)-pipecolic acid
D-pipecolinic acid
D-(R)-(+)-pipecolinic acid tartaric salt
D-(+)-pipercolic acid
(2R)-piperidine-2-carboxylic acid
(R)-piperidine-2-carboxylic acid
(R)-(+)-piperidine-2-carboxylic acid
D-piperidine-2-carboxylic acid
(2R)-2-piperidinecarboxylic acid
(R)-(+)-2-piperidinecarboxylic acid
(R)-2-piperidinecarboxylic acid
2-piperidinecarboxylic acid, (2R)-


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D-Pipecolic acid is a normal human metabolite found in human biofluids. Normal adults excrete pipecolic acid primarily as the D-enantiomer even though it is present in the blood stream mainly as the L-enantiomer. It is believed that D-Pipecolic acid originates from the metabolism of intestinal bacteria and from dietary sources. High levels of D-Pipecolic acid are not found in plasma, but they are increased in urine of patients with chronic liver disease. (PMID: 6501504, 6490790, 11719476, 8398594) [HMDB]
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