EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dextro-glucuronic acid
D-glucuronic acid

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Name:(2S,3S,4S,5R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid
CAS Number: 6556-12-3Picture of molecule3D/inchi
Other(deleted CASRN):12758-41-7
ECHA EINECS - REACH Pre-Reg:229-486-4
FDA UNII: 8A5D83Q4RW
Nikkaji Web:J182.291H
Beilstein Number:1727083
MDL:MFCD00077778
XlogP3-AA:-2.30 (est)
Molecular Weight:194.14010000
Formula:C6 H10 O7
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
D-glucuronate 98%
BOC Sciences
For experimental / research use only.
D-Glucuronic acid
Glentham Life Sciences
D-Glucuronic acid
Sigma-Aldrich: Sigma
For experimental / research use only.
D-Glucuronic Acid ≥98% (GC)
sds
TCI AMERICA
For experimental / research use only.
D-Glucuronic Acid >96.0%(HPLC)(T)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for dextro-glucuronic acid usage levels up to:
 not for fragrance use.
 
Recommendation for dextro-glucuronic acid flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):6556-12-3
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :94715
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(2S,3S,4S,5R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid
Chemidplus:0006556123
RTECS:LZ8836600 for cas# 6556-12-3
 
References:
 (2S,3S,4S,5R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):94715
Pubchem (cas):6556-12-3
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
Golm Metabolome Database:Search
Metabolomics Database:Search
KEGG (GenomeNet):C00191
HMDB (The Human Metabolome Database):HMDB00127
FooDB:FDB021897
Export Tariff Code:2940.00.6000
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 caper plant
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 cashew sap
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 cherry sour cherry fruit
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 cranberry fruit
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 flax seed
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 guava fruit
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 mustard white mustard seed
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 soybean seed
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Synonyms:
D-glucuronic acid
(2S,3S,4S,5R)-3,4,5,6-tetrahydroxyoxane-2-carboxylic acid
 

Articles:

PubMed:An improved purification method for the lysosomal storage disease protein β-glucuronidase produced in CHO cells.
PubMed:Structure and anticoagulant property of a sulfated polysaccharide isolated from the green seaweed Monostroma angicava.
PubMed:Anatomy, nutritional value and cell wall chemical analysis of foliage leaves of Guadua chacoensis (Poaceae, Bambusoideae, Bambuseae), a promising source of forage.
PubMed:A urinary metabonomics analysis of long-term effect of acetochlor exposure on rats by ultra-performance liquid chromatography/mass spectrometry.
PubMed:D-Galacturonic Acid: A Highly Reactive Compound in Nonenzymatic Browning. 2. Formation of Amino-Specific Degradation Products.
PubMed:Antioxidant and antitumor effects of polysaccharides from the fungus Pleurotus abalonus.
PubMed:Isolation and characterization of monoclonal antibodies specific for chondroitin sulfate E.
PubMed:New structural features of Acacia tortuosa gum exudate.
PubMed:High cell density cultivation of recombinant Escherichia coli strains expressing 2-O-sulfotransferase and C5-epimerase for the production of bioengineered heparin.
PubMed:Welan gum: microbial production, characterization, and applications.
PubMed:Structure elucidation and immunomodulatory activity in vitro of a xylan from roots of Cudrania tricuspidata.
PubMed:New triterpenoid saponins from Ilex cornuta and their protective effects against H2O2-induced myocardial cell injury.
PubMed:Optimization and characterization of purified polysaccharide from Musa sapientum L. as a pharmaceutical excipient.
PubMed:Study of the mechanism of formation of hyaluronan putty at pH 2.5: part II--theoretical analysis.
PubMed:Characterization of phenolics of Sarcandra glabra by non-targeted high-performance liquid chromatography fingerprinting and following targeted electrospray ionisation tandem mass spectrometry/time-of-flight mass spectrometry analyses.
PubMed:Chemical structure and antioxidant activity of the biomacromolecules from paddlefish cartilage.
PubMed:Effect of ionic liquid pretreatment on the structure of hemicelluloses from corncob.
PubMed:Structural and biochemical characterization of glycoside hydrolase family 79 β-glucuronidase from Acidobacterium capsulatum.
PubMed:Biological activities of glucosamine and its related substances.
PubMed:Fractional isolation and chemical structure of hemicellulosic polymers obtained from Bambusa rigida species.
PubMed:Fractionation of alkali-solubilized hemicelluloses from delignified Populus gansuensis: structure and properties.
PubMed:Biosynthetic pathway of sugar nucleotides essential for welan gum production in Alcaligenes sp. CGMCC2428.
PubMed:Evaluation and comparison of the antioxidative potency of various carbohydrates using different methods.
PubMed:The structure of the O-antigen in the endotoxin of the emerging food pathogen Cronobacter (Enterobacter) muytjensii strain 3270.
PubMed:Genistein- and daidzein 7-O-beta-D-glucuronic acid retain the ability to inhibit copper-mediated lipid oxidation of low density lipoprotein.
PubMed:Occurrence, production, and applications of gellan: current state and perspectives.
PubMed:Corncob-induced endo-1,4-beta-d-xylanase of Aspergillus oryzae MTCC 5154: production and characterization of xylobiose from glucuronoxylan.
PubMed:Compositional analysis and rheological properties of gum kondagogu (Cochlospermum gossypium): a tree gum from India.
PubMed:Recombinant synthesis of hyaluronan by Agrobacterium sp.
PubMed:Effect of dimer dissociation on activity and thermostability of the alpha-glucuronidase from Geobacillus stearothermophilus: dissecting the different oligomeric forms of family 67 glycoside hydrolases.
PubMed:Organization of genes required for gellan polysaccharide biosynthesis in Sphingomonas elodea ATCC 31461.
PubMed:Analysis of reducing carbohydrates by reductive tryptamine derivatization prior to micellar electrokinetic capillary chromatography.
PubMed:Biochemical characterization and identification of catalytic residues in alpha-glucuronidase from Bacillus stearothermophilus T-6.
PubMed:Analysis and properties of arabinoxylans from discrete corn wet-milling fiber fractions.
PubMed:Functional characterization of a novel xylanase from a corn strain of Erwinia chrysanthemi.
PubMed:The glucuronic acid utilization gene cluster from Bacillus stearothermophilus T-6.
PubMed:Novel selective and non-selective optical detection of microorganisms.
PubMed:Metabolism of [ring-U-14C] agaritine by precision-cut rat, mouse and human liver and lung slices.
PubMed:Effect of diet on growth and plasma ascorbic acid in chicks.
PubMed:Comparison of the metabolism of 7-ethoxycoumarin and coumarin in precision-cut rat liver and lung slices.
PubMed:Antitumor activities and immunochemical properties of the cell-wall polysaccharides from Aureobasidium pullulans.
PubMed:Degradation of complex carbohydrates by Bifidobacterium spp.
PubMed:The effect of iron on metabolism of vitamin C in chickens.
PubMed:Digestibility of pentose sugars and uronic acids and their effect on chick weight gain and caecal size.
PubMed:The effect of oestradiol-17 on the metabolism of chondroitin sulphate B. V. The effect of oestradiol-17 on the protein content and composition of the uridine diphosphate-D-glucuronic acid-5-epimerase-containing protein fraction of rat skin.
 
Notes:
Glucuronic acid is a carboxylic acid that has the structure of a glucose molecule that has had its sixth carbon atom (of six total) oxidized. The salts of glucuronic acid are known as glucuronates. Glucuronic acid is highly soluble in water. In the animal body, glucuronic acid is often linked to poisonous substances to allow for subsequent elimination, and to hormones to allow for easier transport. These linkages involve O-glycosidic bonds. The process is known as glucuronidation, and the resulting substances are known as glucuronides (or glucuronosides). Glucuronidation uses UDP-glucuronic acid (glucuronic acid linked via a glycosidic bond to uridine diphosphate) as an intermediate. UDP-glucuronic acid is formed in the liver of all animals. [HMDB] Widely distributed in plants, where it occurs in gums, mucilages, saponins and flavone glycosides and in animals as a constit. of mucopolysaccharides. Glycosides are formed in the liver to detoxify poisonous hydroxyl-containing substances. Phenyl, cresyl and indoxyl glycosides are present in normal urine. [CCD]
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