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sodium gluconate
D-gluconic acid sodium salt (1:1)

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Name:sodium 2,3,4,5,6-pentahydroxyhexanoate
CAS Number: 527-07-1Picture of molecule3D/inchi
Other(deleted CASRN):15537-84-5
ECHA EINECS - REACH Pre-Reg:208-407-7
FDA UNII: R6Q3791S76
Molecular Weight:218.13783928
Formula:C6 H11 Na O7
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:sequestrant, yeast food
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
182.6757 Sodium gluconate View - review
JECFA Food Additive: Sodium Gluconate
GSFA Codex: Sodium gluconate (576)
DG SANTE Food Additives:sodium gluconate
FEMA Number:4934 sodium gluconate
FDA:No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):527-07-1 ; SODIUM GLUCONATE
FDA Regulation:
Subpart B--Substances Utilized To Control the Growth of Microorganisms
Sec. 178.1010 Sanitizing solutions.

Subpart G--Sequestrants1
Sec. 182.6757 Sodium gluconate.
Physical Properties:
Appearance:white to tan crystalline powder (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 673.60 °C. @ 760.00 mm Hg (est)
Flash Point: 707.00 °F. TCC ( 375.20 °C. ) (est)
logP (o/w): -3.175 (est)
Soluble in:
 water, 590000 mg/L @ 25 °C (exp)
Insoluble in:
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: chelating agents
skin conditioning
American Elements
Sodium Gluconate 99%
Odor: characteristic
Use: Sodium Gluconate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
BOC Sciences
For experimental / research use only.
Sodium Gluconate
For experimental / research use only.
Gluconic acid sodium salt
ECSA Chemicals
Glentham Life Sciences
Sodium gluconate, USP grade
Glentham Life Sciences
Sodium gluconate
Graham Chemical
Sodium Gluconate
Hebei Daou Technology
Sodium Gluconate
Jungbunzlauer Suisse
Sodium Gluconate EMF 1240
Odor: characteristic
Use: Sodium gluconate EMF 1240 is the mother liquor of the sodium gluconate (CAS-No. 527-07-1) production, having similar properties to dry sodium gluconate. Non-corrosive, non-toxic and easily biodegradable, sodium gluconate EMF 1240 is getting more and more appreciated as concrete set retarding and plasticising agent.
Jungbunzlauer Suisse
Sodium Gluconate
Odor: bland
Use: Sodium gluconate is the sodium salt of gluconic acid, produced by fermentation of glucose. It is a white to tan, granular to fine, crystalline powder, very soluble in water. Non corrosive, non toxic and readily biodegradable (98% after 2 days), sodium gluconate is more and more appreciated as chelating agent.
Kraft Chemical
Sodium Gluconate
Krunal Group
Sodium Gluconate
Northwestern Extract
Sodium Gluconate FCC
Penta International
Penta International
Pfanstiehl, Inc
Sodium Gluconate, USP (Low Endotoxin)
Santa Cruz Biotechnology
For experimental / research use only.
Sodium Gluconate ≥97%
Sigma-Aldrich: Sigma
For experimental / research use only.
D-Gluconic acid sodium salt ≥99%
Wedor Corporation
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-rabbit LDLo 7630 mg/kg
Archivio di Farmacologia Sperimentale e Scienze Affini. Vol. 68, Pg. 1, 1939.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
sequestrant, yeast food
Recommendation for sodium gluconate usage levels up to:
 not for fragrance use.
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 29. Update in publication number(s): 30
Click here to view publication 29
 average usual ppmaverage maximum ppm
baked goods: 5000.0000020000.00000
beverages(nonalcoholic): 1500.000003500.00000
beverages(alcoholic): 1500.000003500.00000
breakfast cereal: 2500.000005000.00000
cheese: 5000.0000020000.00000
chewing gum: 10000.0000020000.00000
condiments / relishes: 2500.000005000.00000
confectionery froastings: 1500.000002500.00000
egg products: 2500.000005000.00000
fats / oils: 5000.0000010000.00000
fish products: 5000.0000020000.00000
frozen dairy: 1500.000002500.00000
fruit ices: 1500.000002500.00000
gelatins / puddings: 1500.000002500.00000
granulated sugar: --
gravies: 2500.000005000.00000
hard candy: 10000.0000020000.00000
imitation dairy: 5000.0000010000.00000
instant coffee / tea: 1500.000002500.00000
jams / jellies: 1000.000002500.00000
meat products: 5000.0000020000.00000
milk products: 2500.000005000.00000
nut products: 2500.000005000.00000
other grains: 1500.000005000.00000
poultry: 5000.0000020000.00000
processed fruits: 1500.000002500.00000
processed vegetables: 2500.000005000.00000
reconstituted vegetables: 5000.0000020000.00000
seasonings / flavors: 2500.0000020000.00000
snack foods: 2500.000005000.00000
soft candy: 1500.000002500.00000
soups: 2500.000005000.00000
sugar substitutes: 1500.000003500.00000
sweet sauces: 1500.000003500.00000
Safety References:
EPI System: View
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):527-07-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :517056
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
sodium 2,3,4,5,6-pentahydroxyhexanoate
RTECS:LZ5235000 for cas# 527-07-1
 sodium 2,3,4,5,6-pentahydroxyhexanoate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:527-07-1
Pubchem (cid):517056
Pubchem (sid):134978407
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
FDA Indirect Additives used in Food Contact Substances:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2918.16.5010
FDA Listing of Food Additive Status:View
Potential Blenders and core components note
None Found
Potential Uses:
 chelating agents
Occurrence (nature, food, other):note
 not found in nature
 gluconic acid sodium salt
D-gluconic acid sodium salt
dextro-gluconic acid sodium salt
D-gluconic acid sodium salt (1:1)
dextro-gluconic acid sodium salt (1:1)
 gluconic acid, sodium salt
 hexonic acid, sodium salt (1:1)
 sodium 2,3,4,5,6-pentahydroxy-1-hexanoate
 sodium 2,3,4,5,6-pentahydroxyhexanoate
 sodium D-gluconate
 sodium galactonate
monosodium gluconate


PubMed:Spontaneous supersaturation of calcium D-gluconate during isothermal dissolution of calcium L-lactate in aqueous sodium D-gluconate.
PubMed:Aqueous solubility of calcium L-lactate, calcium D-gluconate, and calcium D-lactobionate: importance of complex formation for solubility increase by hydroxycarboxylate mixtures.
PubMed:Bitter taste inhibiting agents for whey protein hydrolysate and whey protein hydrolysate beverages.
PubMed:Effect of sodium gluconate on the solubility of calcium lactate.
PubMed:A comparative study of antioxidative activity of calcium-D-glucarate, sodium-D-gluconate and D-glucono-1,4-lactone in a human blood platelet model.
PubMed:Gluconic acid production.
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Flavouring ingredient, sequestrant
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