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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 740.60 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 755.00 °F. TCC ( 401.70 °C. ) (est)
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| logP (o/w): | 3.370 |
| Soluble in: |
| | water, 1.28 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 30 mg/kg
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 38, Pg. 438, 1979.
intraperitoneal-rat LD50 11 mg/kg
LUNGS, THORAX, OR RESPIRATION: CYANOSIS
BEHAVIORAL: ATAXIA
BEHAVIORAL: COMA
Toxicon. Vol. 17, Pg. 137, 1979.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for cytochalasin B usage levels up to: | | | not for fragrance use.
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| Recommendation for cytochalasin B flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| (E,E)-16- | benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-2H-oxacyclotetradec[2,3-d]isoindole-2,18(5H)-dione | | 2H-oxa | cyclotetradecino(2,3-d)isoindole-2,18(5H)-dione, 16-benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-, (E,E | | (7S,13E,16R,20R,21E)-7,20- | dihydroxy-16-methyl-10-phenyl-24-oxo[14]cytochalasa-6(12),13,21-triene-1,23-dione | | 7(S),20(R)- | dihydroxy-16(R)-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13(E),21(E)-triene-1,23-dione | | | phomin |
Articles:
| PubMed:Comparative genotoxicity of nanosilver in human liver HepG2 and colon Caco2 cells evaluated by fluorescent microscopy of cytochalasin B-blocked micronucleus formation. |
| PubMed:Deoxynivalenol induced oxidative stress and genotoxicity in human peripheral blood lymphocytes. |
| PubMed:Effect of Cytochalasin B, Lantrunculin B, Colchicine, Cycloheximid, Dimethyl Sulfoxide and Ion Channel Inhibitors on Biospeckle Activity in Apple Tissue. |
| PubMed:Chemical composition of currant seed extracts and their protective effect on human lymphocytes DNA. |
| PubMed:Bisphenol A impairs insulin signaling and glucose homeostasis and decreases steroidogenesis in rat testis: an in vivo and in silico study. |
| PubMed:Blackberry seed extracts and isolated polyphenolic compounds showing protective effect on human lymphocytes DNA. |
| PubMed:Present status and future perspectives on the development of bioartificial kidneys for the treatment of acute and chronic renal failure patients. |
| PubMed:Phloroglucinols inhibit chemical mediators and xanthine oxidase, and protect cisplatin-induced cell death by reducing reactive oxygen species in normal human urothelial and bladder cancer cells. |
| PubMed:Antioxidant properties of raspberry seed extracts on micronucleus distribution in peripheral blood lymphocytes. |
| PubMed:Use of Tetrahymena thermophila to study the role of protozoa in inactivation of viruses in water. |
| PubMed:A nonradioisotope, enzymatic assay for 2-deoxyglucose uptake in L6 skeletal muscle cells cultured in a 96-well microplate. |
| PubMed:Simple-sugar meals target GLUT2 at enterocyte apical membranes to improve sugar absorption: a study in GLUT2-null mice. |
| PubMed:Mapping cholesteryl ester analogue uptake and intracellular flow in Paramecium by confocal fluorescence microscopy. |
| PubMed:Induction of micronuclei in V79 cells after combined treatments with heterocyclic aromatic amines. |
| PubMed:Glucose tolerance and peripheral glucose utilization in rainbow trout (Oncorhynchus mykiss), American eel (Anguilla rostrata), and black bullhead catfish (Ameiurus melas). |
| PubMed:Accumulation and degradation in the endoplasmic reticulum of a truncated ER-60 devoid of C-terminal amino acid residues. |
| PubMed:Assessment of the adaptive response induced by quercetin using the MNCB peripheral blood human lymphocytes assay. |
| PubMed:Reversible increase in tight junction permeability to macromolecules in rat ileal mucosa in vitro by sodium caprate, a constituent of milk fat. |
| PubMed:Characterization of skeletal muscle actin labeled with the triplet probe erythrosin-5-iodoacetamide. |
| PubMed:[An inhibitory analysis of the role of the enterocyte cytoskeleton in the absorption of food substances in the small intestine]. |
| PubMed:Insulin and IGE-1 receptors in a human intestinal adenocarcinoma cell line (CACO-2): regulation of Na+ glucose transport across the brush border. |
| PubMed:[125I]-labeled forskolin analogs which discriminate adenylyl cyclase and a glucose transporter: pharmacological characterization and localization of binding sites in rat brain by in vitro receptor autoradiography. |
| PubMed:An extract of Gymnema sylvestre leaves and purified gymnemic acid inhibits glucose-stimulated gastric inhibitory peptide secretion in rats. |
| PubMed:Cytoskeletal modulation of plasma membrane events induced by interferon-alpha. |
| PubMed:Differential identification and localization of adenylyl cyclase and glucose transporter in brain using iodinated derivatives of forskolin. |
| PubMed:Drugs affecting microtubule dynamics increase alpha-tubulin mRNA accumulation via transcription in Tetrahymena thermophila. |
| PubMed:Interaction of aminoalkylcarbamates of forskolin with adenylyl cyclase: synthesis of an iodinated derivative of forskolin with high affinity for adenylyl cyclase. |
| PubMed:Interaction of forskolin with the P-glycoprotein multidrug transporter. |
| PubMed:Forskolin photoaffinity labels with specificity for adenylyl cyclase and the glucose transporter. |
| PubMed:Adaptation of glucose transport across rat enterocyte basolateral membrane in response to altered dietary carbohydrate intake. |
| PubMed:Decrease in muscle glucose transporter number in chronic physical inactivity in rats. |
| PubMed:Processing of the lipid-mobilizing peptide beta-lipotropin in rabbit adipose tissue. |
| PubMed:Regulation of glucose transporter-specific mRNA levels in rat adipose cells with fasting and refeeding. Implications for in vivo control of glucose transporter number. |
| PubMed:Divergent mechanisms for the insulin resistant and hyperresponsive glucose transport in adipose cells from fasted and refed rats. Alterations in both glucose transporter number and intrinsic activity. |
| PubMed:Mechanism of the decrease in hexose transport by mouse mammary epithelial cells caused by fasting. |
| PubMed:Lysosomal enzyme release from macrophages: a model of food yeast toxicity evaluation. |
| PubMed:Observations by immunofluorescence microscopy and electron microscopy on the cytopathogenicity of Naegleria fowleri in mouse embryo-cell cultures. |
| PubMed:The relationship between energy-dependent phagocytosis and the rate of oxygen consumption in Tetrahymena. |
| PubMed:Acute toxic effects of chaetoglobosin A, a new cytochalasan compound produced by Chaetomium globosum, on mice and rats. |
| PubMed:Fine structure and RNA synthesis of Tetrahymena during cytochalasin B inhibition of phagocytosis. |
| PubMed:Motility in Echinosphaerium nucleofilum. II. Cytoplasmic contractility and its molecular basis. |
| PubMed:The case against the blighted potato. |
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3D/inchi