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cyclooctane
octamethylene

Supplier Sponsors

Name:cyclooctane
CAS Number: 292-64-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:206-031-8
FDA UNII: KKZ3KBS654
Nikkaji Web:J31.686E
Beilstein Number:1900349
MDL:MFCD00004162
XlogP3:4.50 (est)
Molecular Weight:112.21552000
Formula:C8 H16
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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PubMed:Search
NCBI:Search
 
Physical Properties:
Appearance:colorless liquid or solid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Specific Gravity:0.83600 to 0.83800 @ 20.00 °C.
Pounds per Gallon - (est).: 6.964 to 6.981
Refractive Index:1.45800 to 1.45900 @ 20.00 °C.
Melting Point: 14.00 to 15.00 °C. @ 760.00 mm Hg
Boiling Point: 149.00 °C. @ 760.00 mm Hg
Vapor Pressure:16.000000 mmHg @ 37.70 °C.
Flash Point: 82.00 °F. TCC ( 28.00 °C. )
logP (o/w): 4.450
Soluble in:
 alcohol
 water, 7.9 mg/L @ 25 °C (exp)
Insoluble in:
 water
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
EMD Millipore
For experimental / research use only.
Cyclooctane
Santa Cruz Biotechnology
For experimental / research use only.
Cyclooctane
Sigma-Aldrich: Aldrich
For experimental / research use only.
Cyclooctane ≥99%
TCI AMERICA
For experimental / research use only.
Cyclooctane >98.0%(GC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for cyclooctane usage levels up to:
 not for fragrance use.
 
Recommendation for cyclooctane flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :9266
National Institute of Allergy and Infectious Diseases:Data
WISER:UN 3295
WGK Germany:2
cyclooctane
Chemidplus:0000292648
 
References:
 cyclooctane
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):9266
Pubchem (sid):134974633
Pherobase:View
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2902.19.0050
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 beef raw beef
Search PMC Picture
 pork fried pork
Search PMC Picture
 
Synonyms:
 octamethylene
 

Articles:

PubMed:Carbon-Hydrogen Activation of Cycloalkanes by Cyclopentadienylcarbonylrhodium-A Lifetime Enigma.
PubMed:A novel synthetic approach to the bicyclo[5.3.1]undecan-11-one framework of vinigrol.
PubMed:Development of GoSlo-SR-5-69, a potent activator of large conductance Ca2+-activated K+ (BK) channels.
PubMed:Construction of the basic skeleton of ophiobolin A and variecolin.
PubMed:Diels-Alder reaction for tumor pretargeting: in vivo chemistry can boost tumor radiation dose compared with directly labeled antibody.
PubMed:Kinetics study of the reaction of OH radicals with C5-C8 cycloalkanes at 240-340 K using the relative rate/discharge flow/mass spectrometry technique.
PubMed:Highly active catalysts for the transfer dehydrogenation of alkanes: synthesis and application of novel 7-6-7 ring-based pincer iridium complexes.
PubMed:Complexes with hybrid phosphorus-NHC ligands: pincer-type Ir hydrides, dinuclear Ag and Ir and tetranuclear Cu and Ag complexes.
PubMed:Interpreting medium ring canonical conformers by a triangular plane tessellation of the macrocycle.
PubMed:Oxorhenium(V) complexes of quinoline and isoquinoline carboxylic acids--synthesis, structural characterization and catalytic application in epoxidation reactions.
PubMed:Doped graphene as a metal-free carbocatalyst for the selective aerobic oxidation of benzylic hydrocarbons, cyclooctane and styrene.
PubMed:Enzyme-catalyzed synthesis of aliphatic-aromatic oligoamides.
PubMed:The great diversity of HMX conformers: probing the potential energy surface using CCSD(T).
PubMed:Proton-bridge motions in amine conjugate acid ions having intramolecular hydrogen bonds to hydroxyl and amine groups.
PubMed:Oxidation of cycloalkanes by H2O2 using a copper-hemicryptophane complex as a catalyst.
PubMed:Two- and three-dimensional standing waves in a reaction-diffusion system.
PubMed:Exploring the energy landscapes of flexible molecular loops using higher-dimensional continuation.
PubMed:Heterometallic Co(III)4Fe(III)2 Schiff base complex: structure, electron paramagnetic resonance, and alkane oxidation catalytic activity.
PubMed:Improving the affinity and activity of CYP101D2 for hydrophobic substrates.
PubMed:Catalytic hydrogen evolution from a covalently linked dicobaloxime.
PubMed:Attenuated total reflection infrared difference spectroscopy (ATR-IRDS) for quantitative reaction monitoring.
PubMed:Tetradentate Schiff base ligands and their complexes: synthesis, structural characterization, thermal, electrochemical and alkane oxidation.
PubMed:Correlations between conjugation length, macromolecular dynamics, and photophysics of phenylene-vinylene/aliphatic multiblock copolymers.
PubMed:Reactions of OH radicals with C6-C10 cycloalkanes in the presence of NO: isomerization of C7-C10 cycloalkoxy radicals.
PubMed:Synthesis and antimicrobial evaluation of some new cyclooctanones and cyclooctane-based heterocycles.
PubMed:Synthesis of a fluorogenic cyclooctyne activated by Cu-free click chemistry.
PubMed:Membrane labeling and immobilization via copper-free click chemistry.
PubMed:Synthetic studies on dicyclopenta[a,d]cyclooctane terpenoids: construction of the core structure of fusicoccins and ophiobolins on the route involving a Wagner-Meerwein rearrangement.
PubMed:Efficient catalytic cycloalkane oxidation employing a "helmet" phthalocyaninato iron(III) complex.
PubMed:Atmospheric-pressure, liquid-phase, selective aerobic oxidation of alkanes catalysed by metal-organic frameworks.
PubMed:Development of Photocrosslinkable Urethane-Doped Polyester Elastomers for Soft Tissue Engineering.
PubMed:Rh-catalyzed [7 + 1] cycloaddition of buta-1,3-dienylcyclopropanes and CO for the synthesis of cyclooctadienones.
PubMed:Screening of a minimal enriched P450 BM3 mutant library for hydroxylation of cyclic and acyclic alkanes.
PubMed:Synthesis of oligoribonucleic acid conjugates using a cyclooctyne phosphoramidite.
PubMed:Labeling study of avidin by modular method for affinity labeling (MoAL).
PubMed:Topology of cyclo-octane energy landscape.
PubMed:Citric-acid-derived photo-cross-linked biodegradable elastomers.
PubMed:Structure-activity analysis of vinylogous urea inhibitors of human immunodeficiency virus-encoded ribonuclease H.
PubMed:Metalloradical-catalyzed aliphatic carbon-carbon activation of cyclooctane.
PubMed:Synthesis and characterization of a biodegradable elastomer featuring a dual crosslinking mechanism.
PubMed:Solvation shell structure of cyclooctylpyranone in water solvent and its comparative structure, dynamics and dipole moment in HIV protease.
PubMed:Clickable fluorophores for biological labeling--with or without copper.
PubMed:Effects of native organic material and water on sorption properties of reference diesel soot.
PubMed:Zirconium complex of an [OSSO]-type diphenolate ligand bearing trans-1,2-cyclooctanediylbis(thio) core: synthesis, structure, and isospecific 1-hexene polymerization.
PubMed:Ring strain energy in the cyclooctyl system. The effect of strain energy on [3 + 2] cycloaddition reactions with azides.
PubMed:Characterization of sorbent properties of soil organic matter and carbonaceous geosorbents using n-alkanes and cycloalkanes as molecular probes.
PubMed:Transformation of the hexagonal-structure clathrate hydrate of cyclooctane to a low-symmetry form below 167 k.
PubMed:Dual types of spherulites in poly(octamethylene terephthalate) confined in thin-film growth.
PubMed:Tetrazine ligation: fast bioconjugation based on inverse-electron-demand Diels-Alder reactivity.
PubMed:Contiguously substituted cyclooctane polyols. configurational assignments via (1)H NMR correlations and symmetry considerations.
PubMed:Algorithmic dimensionality reduction for molecular structure analysis.
PubMed:Design, synthesis and pharmacological evaluation of hybrid molecules out of quinazolinimines and lipoic acid lead to highly potent and selective butyrylcholinesterase inhibitors with antioxidant properties.
PubMed:Nonelectrical poling in ferroelectric polythioureas.
PubMed:2-Chloro-12-phenyl-6,7,8,9,10,11-hexa-hydro-cyclo-octa-[b]quinoline.
PubMed:Catalytic ring expansion, contraction, and metathesis-polymerization of cycloalkanes.
PubMed:Packing in three cyclooctitol acetates.
PubMed:Studies towards the total synthesis of di- and sesterterpenes with dicyclopenta[a,d]cyclooctane skeletons. Three-component approach to the A/B rings building block.
PubMed:1'-Methylcyclooctane-1-spiro-3'-pyrrolidine-2'-spiro-3''-indoline-2,2''-dione and 1,1'-dimethylpiperidine-3-spiro-3'-pyrrolidine-2'-spiro-3''-indoline-2'',4-dione.
PubMed:A hydrophilic cyclodextrin duplex forming supramolecular assemblies by physical cross-linking of a biopolymer.
PubMed:Cyclooctane tropospheric degradation initiated by reaction with C1 atoms.
PubMed:Synthesis and catalytic properties in olefin epoxidation of novel iron(II) complexes with pyridine-containing macrocycles bearing an aminopropyl pendant arm.
PubMed:Emission switching of ferrocenyl Schiff bases and a representative ruthenium complex in alkaline DMSO: absorption, electrochemical and microstructural studies.
PubMed:Structure-activity relationships of methoctramine-related polyamines as muscarinic antagonist: effect of replacing the inner polymethylene chain with cyclic moieties.
PubMed:Analysis of guazatine mixture by LC and LC-MS and antimycotic activity determination of principal components.
PubMed:Cucurbituril binding of trans-[{PtCl(NH3)2}2(micro-NH2(CH2)8NH2)]2+ and the effect on the reaction with cysteine.
PubMed:Encapsulation of a guest molecule in a strained form: an extended 36-membered dodecanuclear manganese metallamacrocycle that accommodates a cyclooctane in the S4 symmetry conformation.
PubMed:Transition-metal (Ti,V,Cr,Mn,Fe,Co,Cu) containing ordered nanoporous materials: novel heterogeneous catalysts for selective oxidation reactions.
PubMed:Homobivalent quinazolinimines as novel nanomolar inhibitors of cholinesterases with dirigible selectivity toward butyrylcholinesterase.
PubMed:Saturated hydrocarbon-benzene complexes: theoretical study of cooperative CH/pi interactions.
PubMed:From common carbohydrates to enantiopure cyclooctane polyols and glycomimetics via deoxygenative zirconocene ring contraction.
PubMed:Triplet energy back transfer in conjugated polymers with pendant phosphorescent iridium complexes.
PubMed:Supramolecular assemblies of a new series of gemini-type schiff base amphiphiles at the air/water interface: in situ coordination, interfacial nanoarchitectures, and spacer effect.
PubMed:Self-inclusion behavior and circular dichroism of aliphatic chain-linked beta-cyclodextrin-viologen compounds and their reduced forms depending on the side of modification.
PubMed:Three-carbon Dowd-Beckwith ring expansion reaction versus intramolecular 1,5-hydrogen transfer reaction: a theoretical study.
PubMed:Studies toward the total synthesis of vinigrol. synthesis of the octalin ring.
PubMed:Bayesian methods for the conformational classification of eight-membered rings.
PubMed:Europium(II) and ytterbium(II) cyclic organohydroborates with agostic interactions.
PubMed:Enantioselective route from carbohydrates to cyclooctane polyols.
PubMed:Exploratory studies aimed at a synthesis of vinigrol. 2. Attempts to exploit ring-closing metathesis for construction of the central cyclooctane belt.
PubMed:Conformational investigations on analogs of inflammation response inducing chemotactic tripeptide fMLP.
PubMed:Boronic acid based modular fluorescent sensors for glucose.
PubMed:Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties.
PubMed:Phase relationships and thermodynamic interactions of isotactic poly(1-butene) and organic solvent systems.
PubMed:A combined experimental and computational study of dihydrido(phosphinooxazoline)iridium complexes.
PubMed:Effect of surface wettability on the adhesion of proteins.
PubMed:Mechanistic studies of the transfer dehydrogenation of cyclooctane catalyzed by iridium bis(phosphinite) p-XPCP pincer complexes.
PubMed:Alkane oxidation via photochemical excitation of a self-assembled molecular cage.
PubMed:Peptide helices with pendant cycloalkane rings. Characterization of conformations of 1-aminocyclooctane-1-carboxylic acid (Ac8c) residues in peptides.
PubMed:Aromatic vs aliphatic C-H cleavage of alkyl-substituted pyridines by (PNPiPr)Re compounds.
PubMed:Direct investigation of the fate of NAPL contaminations in a hydrating cement matrix by means of magnetic resonance techniques.
PubMed:Iridium bis(phosphinite) p-XPCP pincer complexes: highly active catalysts for the transfer dehydrogenation of alkanes.
PubMed:Europium(II) and ytterbium(II) cyclic organohydroborates: an europium(II) complex with an agostic interaction.
PubMed:The C7-C10 cycloalkanes revisited.
PubMed:Diazacoronand linked beta-cyclodextrin dimer complexes of Brilliant Yellow tetraanion and their sodium(I) analogues.
PubMed:Mechanism of alkane transfer-dehydrogenation catalyzed by a pincer-ligated iridium complex.
PubMed:Bivalent biogenic amine reuptake inhibitors.
PubMed:Evaluation of different formulation studies on air-filled polymeric microcapsules by multivariate analysis.
PubMed:Indigo production by Escherichia coli carrying the phenol hydroxylase gene from Acinetobacter sp strain ST-550 in a water-organic solvent two-phase system.
PubMed:Synthesis and pharmacological activity of fluorescent histamine H1 receptor antagonists related to mepyramine.
PubMed:From hydrocarbons to polyols. Cyclooctatetraene to novel cyclooctitols.
PubMed:Structural characterisation of bisintercalation in higher-order DNA at a junction-like quadruplex.
PubMed:Multiple active intermediates in oxidation reaction catalyzed by synthetic heme-thiolate complex relevant to cytochrome p450.
PubMed:Selective oxidation of cyclooctane to cyclootanone with molecular oxygen in the presence of compressed carbon dioxide.
PubMed:The effect of a hydroxy protecting group on the PtCl2-catalyzed cyclization of dienynes--a novel, efficient, and selective synthesis of carbocycles.
PubMed:Synthesis of enantiomerically pure, highly functionalized, medium-sized carbocycles from carbohydrates: formal total synthesis of (+)-calystegine b(2).
PubMed:A silica monolithic column prepared by the sol-gel process for enantiomeric separation by capillary electrochromatography.
PubMed:Total synthesis of (+/-)-asteriscanolide.
PubMed:Conformational Study of Oxacyclooctan-2-one by Dynamic NMR Spectroscopy and Computational Methods.
PubMed:Flexibility vs Rigidity of Singly and Doubly Tethered Biphenyls: Structure, Dynamic Stereochemistry, and Resolution of Tribenzo[a,c,f]cyclooctane, Tetrabenzo[a,de,h,kl]bicyclo[6.6.0]tetradecane, and Their Alkyl Derivatives.
PubMed:Trapping-mediated dissociative chemisorption of cycloalkanes on Ru(001) and Ir(111): influence of ring strain and molecular geometry on the activation of C-C and C-H bonds.
PubMed:Separation of enantiomers by open capillary electrochromatography on polysiloxane-bonded permethyl-beta-cyclodextrin.
PubMed:Air-filled polymeric microcapsules from emulsions containing different organic phases.
PubMed:Synthesis and structures of heterocyclic azidogallanes [(CH3)ClGaN3]4 and [(CH3)BrGaN3]3 en route to [(CH3)HGaN3]x: an inorganic precursor to GaN.
PubMed:10-Deacetyl baccatin III dimethyl sulfoxide disolvate.
PubMed:A new thioether-ligated iron porphyrin as a model of a protonated form of P450 active site.
PubMed:A [4 + 4] 2-pyridone approach to taxol. 3. Stereocontrol during elaboration of the cyclooctane.
PubMed:Enantiomer separation by capillary electrochromatography on a cyclodextrin-modified monolith.
PubMed:Catalytic oxidation with a non-heme iron complex that generates a low-spin Fe(III)OOH intermediate
PubMed:Test liquids for quantitative MRI measurements of self-diffusion coefficient in vivo.
PubMed:Syntheses and evaluation of amidinobenzofuran derivatives as tryptase inhibitors.
PubMed:Renal targeting of arginine-vasopressin by modification with carbohydrates at the tyrosine side chain.
PubMed:Enantiomer separation by pressure-supported electrochromatography using capillaries packed with Chirasil-Dex polymer-coated silica.
PubMed:Specific renal delivery of sugar-modified low-molecular-weight peptides.
PubMed:Appearance of a stress-response protein, phage-shock protein A, in Escherichia coli exposed to hydrophobic organic solvents.
PubMed:Hydrophilicity of polymers and soft tissue responses: a quantitative analysis.
PubMed:Anti-AIDS agents--XXVI. Structure-activity correlations of gomisin-G-related anti-HIV lignans from Kadsura interior and of related synthetic analogues.
PubMed:Anesthetic and convulsant properties of aromatic compounds and cycloalkanes: implications for mechanisms of narcosis.
PubMed:Regional distribution of rat electroolfactogram.
PubMed:Enantiomer separation using mobile and immobile cyclodextrin derivatives with electromigration.
PubMed:In vivo evaluation of polyurethanes based on novel macrodiols and MDI.
PubMed:Structure-activity relationship studies with symmetric naphthalenesulfonic acid derivatives. Synthesis and influence of spacer and naphthalenesulfonic acid moiety on anti-HIV-1 activity.
PubMed:[Synthesis of N-substituted polymethylene dicarboxamides as inducers of differentiation].
PubMed:Potential anti-AIDS naphthalenesulfonic acid derivatives. Synthesis and inhibition of HIV-1 induced cytopathogenesis and HIV-1 and HIV-2 reverse transcriptase activities.
PubMed:Lecithin organogel as matrix for transdermal transport of drugs.
PubMed:Structure of (+/-)-(1R*,6S*)-1-benzyloxy-8,11,11-trimethyl-6-phenylthiobicyclo [5.3.1 ]undec-7-en-3-one.
PubMed:The structure of (4R*,7R*)-4,10,11,11-tetramethyl-5- oxobicyclo[5.3.1]undec-1(10)-en-4-carbaldehyde.
PubMed:Structure of (+/-)-(1R*,4S*,6S*)-1-benzyloxy-4,8,11,11-tetramethyl-6- phenylthio-bicyclo[5.3.1]undec-7-en-3-one.
PubMed:Photocleavage of DNA and photofootprinting of E. coli RNA polymerase bound to promoter DNA by azido-9-acridinylamines.
PubMed:Solubility in binary solvent systems: 8. Estimation of binary alkane plus p-dioxane solvent nonideality from measured anthracene solubilities.
PubMed:Developmental toxicity of N,N1-bis(dichloroacetyl)-1,8-octamethylene diamine: effects of in utero exposure on the postnatal murine immune system.
PubMed:Cross-linking between histones and DNA following treatment with a series of dimethane sulphonate esters.
PubMed:Outer membrane porin proteins F, P, and D1 of Pseudomonas aeruginosa and PhoE of Escherichia coli: chemical cross-linking to reveal native oligomers.
PubMed:Loss of hepatic monooxygenase activities, glutathione, and 'green pigment' formation after the administration of vinyl-cyclooctane to mice.
PubMed:[Physiological activity of polymethylene and polyoxyethylene bis-(2-amino-1,3-diazepiniuim) iodides].
PubMed:Formation of a polymethylene bis(disulfide) intersubunit cross-link between cysteine-281 residues in rabbit muscle glyceraldehyde-3-phosphate dehydrogenase using octamethylene bis(methane[35S]thiosulfonate).
PubMed:Solubility in binary solvent systems I: Specific versus nonspecific interactions.
PubMed:[Thin-layer chromatographic determination of N,N'-bis-dichloroacetyl-1,8-octamethylene diamine for the elucidation of deceptive strategems in the expertise of paternity].
PubMed:[Hypocholesterolemic effect and lipid protection of the arterial wall by dimethyl-1,1-dioxa-2,8-hydroxyethyl-5-sila-1-aza-5-cyclooctane (T.E.A.S)].
PubMed:[Synthesis of cyclooctane-1,5-dione derivatives (author's transl)].
PubMed:The fixation of complement and the activated first component (C1) of complement by complexes formed between antibody and divalent hapten.
PubMed:Inhibition of fly head acetylcholinesterase by bis-[(m-hydroxyphenyl)-trimethylammonium iodide] esters of polymethylenedicarbamic acids.
PubMed:The metabolism of the octamethylene-1,8-dithiol moiety of bis(O-acetylthiamine)octamethylene-18,-disulfide in rat and man.
PubMed:[Histochemical studies on the psychomotor end plate of the skeletal muscles on the white mouse after administration of the cholinesterase inhibitors BC 16 (hexamethylene-bis-carbaminoylcholine) and BC 47 (octamethylene-bis-carbaminoyl-m-trimethylammoniumphenol)].
PubMed:[Interaction of d-tubocurarine, eserine and depolarizing substances in isolated rat diaphram, studied with octamethylene-biscarbaminoylcholine].
PubMed:The heats of combustion of cyclopentane, cyclohexane, cycloheptane and cyclooctane.
 
Notes:
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