EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

coumalic acid
2-pyrone-5-carboxylic acid

Supplier Sponsors

Name:6-oxopyran-3-carboxylic acid
CAS Number: 500-05-0Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:207-899-0
FDA UNII: OB1JPY343G
Nikkaji Web:J9.867A
Beilstein Number:0119747
MDL:MFCD00006644
Molecular Weight:140.09468000
Formula:C6 H4 O4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Melting Point: 207.00 to 208.00 °C. @ 760.00 mm Hg
Boiling Point: 282.00 to 283.00 °C. @ 760.00 mm Hg (est)
Boiling Point: 218.00 °C. @ 120.00 mm Hg
Vapor Pressure:0.001000 mmHg @ 25.00 °C. (est)
Flash Point: 279.00 °F. TCC ( 137.30 °C. ) (est)
logP (o/w): 0.411 (est)
Soluble in:
 alcohol
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Coumalic acid 98%
BOC Sciences
For experimental / research use only.
Coumalic acid >95%
Santa Cruz Biotechnology
For experimental / research use only.
Coumalic Acid
Sigma-Aldrich: Aldrich
For experimental / research use only.
Coumalic acid 97%
TCI AMERICA
For experimental / research use only.
Coumalic Acid >97.0%(GC)(T)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for coumalic acid usage levels up to:
 not for fragrance use.
 
Recommendation for coumalic acid flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):500-05-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :68141
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
6-oxopyran-3-carboxylic acid
Chemidplus:0000500050
 
References:
 6-oxopyran-3-carboxylic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):68141
Pubchem (sid):135024339
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2932.20.4500
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 ageratum conyzoides
Search Trop Picture
 
Synonyms:
 coumalicacid
 cumalic acid
2-oxo-1-phenylpyrrolidine-4-carboxylic acid
6-oxopyran-3-carboxylic acid
6-oxo-6H-pyran-3-carboxylic acid
2-oxopyran-5-carboxylic acid
2-oxo-2H-pyran-5-carboxylic acid
2H-pyran-5-carboxylic acid, 2-oxo
2H-pyran-5-carboxylic acid, 2-oxo-
2-pyrone-5-carboxylic acid
a-pyrone-5-carboxylic acid
alpha-pyrone-5-carboxylic acid
 

Articles:

PubMed:Inhibition of Orobanche crenata seed germination and radicle growth by allelochemicals identified in cereals.
PubMed:The inhibiting activity of areca inflorescence extracts on human low density lipoprotein oxidation induced by cupric ion.
PubMed:Stimulation by caffeic acid, coumalic acid, and corilagin of the germination of resting spores of the clubroot pathogen Plasmodiophora brassicae.
PubMed:Characterization and expression of enzymatically active recombinant filarial prolyl 4-hydroxylase.
PubMed:Time-dependent inactivation of chick-embryo prolyl 4-hydroxylase by coumalic acid. Evidence for a syncatalytic mechanism.
 
Notes:
None found
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